Disaggregated Nano-Hydroxyapatite (DnHAP) with Inhibitory Effects on Biofilms and Demineralization

Review Dentistry, Oral Surgery & Medicine

The use of hydroxyapatite toothpaste to prevent dental caries

Kelsey O'Hagan-Wong et al.

Summary: This narrative review aims to summarize recent findings on the remineralization potential of HAP toothpaste in vitro, in situ, and in vivo, as well as other applications in dentistry.

ODONTOLOGY (2022)

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Review Dentistry, Oral Surgery & Medicine

Expert consensus on dental caries management

Lei Cheng et al.

Summary: Dental caries is a chronic oral disease that poses a significant threat to human health. Despite efforts by dentists and researchers, the prevalence of dental caries remains high. Establishing a clinical difficulty assessment system for caries prevention and management based on diagnosis and classification is crucial. Dentists should conduct oral examinations and create dental records during each visit. Personalized treatment plans, based on caries risk assessment and lesion activity, are necessary to restore oral microecological balance, control caries progression, and restore the structure and function of the affected teeth. Follow-up visits should be conducted based on personalized caries management. This expert consensus focuses on caries risk assessment, treatment difficulty assessment, and dental caries treatment plans, which are essential components of caries management throughout the life cycle.

INTERNATIONAL JOURNAL OF ORAL SCIENCE (2022)

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Article Dentistry, Oral Surgery & Medicine

Cross-Kingdom Cell-to-Cell Interactions in Cariogenic Biofilm Initiation

S. X. Wan et al.

Summary: The study revealed differences in binding forces between S. gordonii and S. mutans with Candida albicans, with the latter exhibiting significantly enhanced binding forces when the fungal surface is coated with extracellular glucans. This enhanced binding affinity led to the formation of larger structures during early biofilm initiation and ultimately resulted in the dominance of S. mutans in the 3-species biofilm model under cariogenic conditions.

JOURNAL OF DENTAL RESEARCH (2021)

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Article Multidisciplinary Sciences

Impact of a toothpaste with microcrystalline hydroxyapatite on the occurrence of early childhood caries: a 1-year randomized clinical trial

Elzbieta Paszynska et al.

Summary: The study found that toothpaste with microcrystalline hydroxyapatite is not inferior to fluoride toothpaste in preventing caries in children, demonstrating non-inferiority of the hydroxyapatite toothpaste.

SCIENTIFIC REPORTS (2021)

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Article Chemistry, Multidisciplinary

Hydroxyapatite-Based Solution as Adjunct Treatment for Biofilm Management: An In Situ Study

Cintia M. G. Nobre et al.

Summary: The study found that using hydroxyapatite solution as a mouthwash can effectively reduce biofilm coverage, showing comparable results to chlorhexidine treated samples, without altering the viability of microorganisms.

NANOMATERIALS (2021)

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Article Dentistry, Oral Surgery & Medicine