期刊
JOURNAL OF COLLOID AND INTERFACE SCIENCE
卷 635, 期 -, 页码 456-465出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jcis.2022.12.132
关键词
Biomimetic material; Proteinosome aggregations; Collective behavior; Enzyme immobilization
Compared with individuals, proteinosomes aggregations show superior characteristics including accelerated settling velocity, survival by sacrificing outside members, resistance to negative pressure phagocytosis, and enhanced enzyme utilization rate. The construction and application of proteinosomes aggregations contribute to advancing the functionality of life-like assembled biomaterial.
Compared with the individuals, the collective behavior of biotic communities could show certain superior characteristics. Inspired by this idea and based on the conjugation between phenylboronic acid-grafted mesoporous silica nanoparticles and the polysaccharide functionalized membrane of proteinosomes, a type of proteinosomes-based aggregations was constructed. We demonstrated the emergent characteris-tics of proteinosomes aggregations including accelerated settling velocity and population surviving by sacrificing outside members for the inside. Moreover, this kind of hand in hand architecture provided the proteinosomes aggregations with the characteristic of resistance to the negative pressure phagocyto-sis of micropipette, as well as enhancing utilization rate of the encapsulated enzymes. Overall, it is anticipated that the construction and application of proteinosomes aggregations could contribute to advance the functionality of life-like assembled biomaterial in another way.(c) 2022 Elsevier Inc. All rights reserved.
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