(Fe3O4@SiO2/GO-NH2-CoII NPs): A Novel and Efficient Nanomagnetic Heterogeneous Cobalt Catalysis in the Sonogashira and Heck-Mizoroki Coupling Reactions

A Co(II) complex (Fe3O4@SiO2/GO-NH2-Co-II NPs) immobilized on a magnetic graphene oxide nanocomposite was efficiently synthesized and characterized by a variety of techniques, including XRD, FT-IR, SEM/EDX, TEM, VSM, TGA and AAS. Then, the catalytic activity of this new Fe3O4@SiO2/GO-NH2-Co-II complex was examined in the Sonogashira cross-coupling reaction and Heck-Mizoroki coupling reaction. The Pd/Cu-free Sonogashira cross-coupling reaction of different aryl halides and terminal alkynes was achieved in the presence of Fe3O4@SiO2/GO-NH2-Co-II NPs under reflux in ethanol, and the corresponding products were obtained successfully in good to high yields. In addition, Heck-Mizoroki cross-coupling reactions of various aryl halides by using Fe3O4@SiO2/GO-NH2-Co-II and Et3N under reflux in DMSO afforded the desired products in good to high yields. This heterogeneous catalyst can be recovered using a magnet and reused several times without obvious loss of catalytic activity.

Automated summary

A Co(II) complex immobilized on a magnetic graphene oxide nanocomposite was synthesized and characterized by various techniques. The catalytic activity of this complex in Sonogashira cross-coupling reaction and Heck-Mizoroki coupling reaction was examined. The results showed that the complex exhibited high catalytic activity and could be easily recovered and reused.