The BIGG-REC database makes available all WHO/PAHO evidence informed recommendations

Objectives: To build and maintain a living database of the Pan American Health Organization/World Health Organization (PAHO/ WHO) recommendations developed using Grading of Recommendations Assessment, Development, and Evaluation (GRADE).Study Design and Setting: Guidelines are identified from WHO and PAHO databases. We periodically extract recommendations, according to the health and well-being targets of sustainable development goal 3 (SDG-3).Results: As of March 2022, the International database of GRADE guidelines (https://bigg-rec.bvsalud.org/en) database hosted 2,682 recommendations contained in 285 WHO/PAHO guidelines. Recommendations were classified as follows: communicable diseases (1,581), children's health (1,182), universal health (1,171), sexual and reproductive health (910), noncommunicable diseases (677), maternal health (654), COVID-19 (224), use of psychoactive substances (99), tobacco (14) and road and traffic accidents (16). International database of GRADE guidelines allows searching by SDG-3, condition or disease, type of intervention, institution, year of publication, and age.Conclusion: Recommendation maps provide an important resource for health professionals, organizations and member states that use evidence-informed guidance to make better decisions, providing a source for the adoption or adaptation of recommendations to meet their needs. This one-stop shop database of evidence-informed recommendations built with intuitive functionalities undoubtedly represents a long-needed tool for decision-makers, guideline developers, and the public at large.& COPY; 2023 Pan American Health Organization. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Automated summary

This article describes the establishment and maintenance of a living database of recommendations developed by the PAHO/WHO using the GRADE assessment system. The database provides a valuable resource for health professionals and organizations to make evidence-informed decisions. It allows searching and filtering recommendations by various criteria.