☆ 4.7 Article

Elucidation of binding mechanism of rhodanine derivative P4OC on bovine serum albumin

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemistry & Molecular Biology

Spectroscopic investigations on fungal aspartic protease as target of gallic acid

Ziaul Hasan et al.

Summary: In this study, the interaction between gallic acid (GA) and Aspartic fungal protease (PepA) was investigated using biophysical and in silico approaches. The results showed that GA strongly binds to PepA, leading to structural disruption and inhibition of its activity. However, the binding of GA to Human Serum albumin (HSA) was moderate and did not cause structural disruption.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

添加到收藏夹

Review Biochemistry & Molecular Biology

Systematic interaction of plasma albumin with the efficacy of chemotherapeutic drugs

Liuchunyang Yu et al.

Summary: Albumin, as the most abundant plasma protein, plays a crucial role in the transport and efficacy of chemotherapeutic drugs. It affects drug outcomes, toxicity, tumor proliferation, and metabolism by binding to exogenous and endogenous ligands, such as fatty acids. Additionally, albumin-based carriers are utilized for anti-tumor drug delivery.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2022)

添加到收藏夹

Review Medicine, Research & Experimental

Review of anticancer potentials and structure-activity relationships (SAR) of rhodanine derivatives

Lim Ju Yin et al.

Summary: Rhodanine is a privileged scaffold in medicinal chemistry with significant potential for cancer treatment, demonstrating broad biological activities and structural diversification for effective drug discovery. Rhodanine-derived compounds have shown promising anticancer activity while maintaining low cytotoxicity, highlighting their value for future cancer drug development.

BIOMEDICINE & PHARMACOTHERAPY (2022)

添加到收藏夹

Article Chemistry, Applied

Studies on the interactions of theaflavin-3,3′-digallate with bovine serum albumin: Multi-spectroscopic analysis and molecular docking

Xia Yu et al.

Summary: By utilizing various experimental techniques such as fluorescence spectroscopy and UV-vis absorption spectroscopy, the interaction mechanism between theaflavin-3,3'-digallate (TFDG) and bovine serum albumin (BSA) was studied, demonstrating that hydrophobic interactions and hydrogen bonds play a dominant role in their interaction. This research provides the possibility for further development of nanoparticles with superior biochemical properties and potential exploration of BSA as a transport carrier for TFDG.

FOOD CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Effects of Myristate on the Induced Circular Dichroism Spectra of Aripiprazole Bound to Human Serum Albumin: A Structural-Chemical Investigation

Kenshiro Hirata et al.

Summary: The study found that myristate can affect the induced circular dichroism spectra of aripiprazole bound to human serum albumin, and can displace aripiprazole molecules from albumin.

ACS OMEGA (2022)

添加到收藏夹

Article Chemistry, Physical

Mechanistic competitive binding interaction study between olmutinib and colchicine with model transport protein using spectroscopic and computer simulation approaches

Tanveer A. Wani et al.

Summary: This study investigated the binding and displacement interaction of olmutinib and colchicine with bovine serum albumin (BSA) using spectroscopic and molecular simulation methods. The presence of either drug influenced their binding to BSA, with olmutinib showing a higher binding capacity. These findings are important for understanding the pharmacological effects of these drugs in the body.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Multi-spectroscopic studies of the interaction of new synthesized platin complex with human carrier protein of serum albumin

Azadeh Mohammadgholi et al.

Summary: The study investigated the interaction of a new synthesized Pt [iso]2 complex with HSA using fluorescence and circular dichroic methods at two different temperatures. The analysis revealed that a static mechanism played a key role in fluorescence quenching, with one binding site for the complex at both temperatures. The secondary structure of the protein did not significantly change in the presence of the Pt [iso]2 complex, but thermal stability was reduced, highlighting the potential impact on drug design.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2021)

添加到收藏夹

Article Spectroscopy

Spectroscopic and molecular modelling study of binding mechanism of bovine serum albumin with phosmet

Afreen Jahan Rahman et al.

Summary: Phosmet exerts its neurotoxicity by inhibiting acetylcholinesterase, while the binding interactions with bovine serum albumin (BSA) influenced the free concentration of Phosmet. The study confirmed non-covalent binding interactions between Phosmet and BSA.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2021)

添加到收藏夹

Article Chemistry, Physical

Spectroscopic studies of binding interactions of 2-chloroethylphenyl sulphide with bovine serum albumin

Afreen Jahan Rahman et al.

Summary: In this study, the binding interaction between CEPS and BSA was investigated using various techniques, showing a complex binding and changes in the microenvironment of BSA's fluorescence groups. The binding is driven by non-covalent interactions and thermodynamic parameters, suggesting it is enthalpy-driven and spontaneous in nature.

JOURNAL OF MOLECULAR LIQUIDS (2021)

添加到收藏夹

Article Chemistry, Applied

Studying the interaction mechanism between bovine serum albumin and lutein dipalmitate: Multi-spectroscopic and molecular docking techniques

Xin Qi et al.

Summary: The interaction between lutein dipalmitate and BSA was found to be static with a binding stoichiometry of 1:1. Thermodynamic study and molecular docking confirmed that lutein dipalmitate spontaneously bound to BSA through hydrogen bonds, van der Waals forces, and hydrophobic interactions. The addition of lutein dipalmitate led to a decrease in the alpha-helix content of BSA, as observed through CD analysis.

FOOD HYDROCOLLOIDS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

HPTLC analysis of Fumaria parviflora (Lam.) methanolic extract of whole plant

Anjali Bhargava et al.

Summary: The study found that the methanolic extract of the whole plant of F. parviflora contains a diverse range of phytochemicals, which may contribute to its therapeutic value, supporting its traditional use in India.

FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

In vitro studies of potent aldose reductase inhibitors: Synthesis, characterization, biological evaluation and docking analysis of rhodanine-3-hippuric acid derivatives

Stephen Kumar Celestina et al.

BIOORGANIC CHEMISTRY (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

A Review on Applications of Computational Methods in Drug Screening and Design

Xiaoqian Lin et al.

MOLECULES (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Role of pharmacokinetic consideration for the development of drug delivery systems: A historical overview

Mitsuru Hashida

ADVANCED DRUG DELIVERY REVIEWS (2020)

添加到收藏夹

Article Spectroscopy

Binding interaction of potent HIV-1 NNRTIs, amino-oxy-diarylquinoline with the transport protein using spectroscopic and molecular docking

Suwicha Patnin et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Multi-spectroscopic investigation, molecular docking and molecular dynamic simulation of competitive interactions between flavonoids (quercetin and rutin) and sorafenib for binding to human serumalbumin

Nawaf A. Alsaif et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Article Spectroscopy

Spectroscopic evaluation of Zn (II) complexes with drug analogues: Interactions with BSA and the pH effect on the drug-Zn (II) system

Manolis C. Vlasiou et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Synthesis, structure and characterization of new dithiocarbazate-based mixed ligand oxidovanadium(iv) complexes: DNA/HSA interaction, cytotoxic activity and DFT studies

Atanu Banerjee et al.

NEW JOURNAL OF CHEMISTRY (2020)

添加到收藏夹

Letter Biochemistry & Molecular Biology

Molecular binding mechanism of 5-hydroxy-1-methylpiperidin-2-one with human serum albumin

Sangilimuthu Alagar Yadav et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2018)

添加到收藏夹

Article Chemistry, Applied

Interactions of different polyphenols with bovine serum albumin using fluorescence quenching and molecular docking

Mihaela Skrt et al.

FOOD CHEMISTRY (2012)

添加到收藏夹

Article Biochemistry & Molecular Biology

Interaction between a potent corticosteroid drug - Dexamethasone with bovine serum albumin and human serum albumin: A fluorescence quenching and fourier transformation infrared spectroscopy study

P. N. Naik et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2010)

添加到收藏夹

Article Biochemistry & Molecular Biology

Betulinic acid binding to human serum albumin: A study of protein conformation and binding affinity

Rajagopal Subramanyam et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2009)

添加到收藏夹

Article Chemistry, Multidisciplinary

Self-Assembly of Ibuprofen and Bovine Serum Albumin-Dextran Conjugates Leading to Effective Loading of the Drug

Juan Li et al.

LANGMUIR (2009)

添加到收藏夹

Article Optics

Modification of single molecule fluorescence near metallic nanostructures

Yi Fu et al.

LASER & PHOTONICS REVIEWS (2009)

添加到收藏夹

Article Spectroscopy

Molecular simulation of the interaction between novel type rhodanine derivative probe and bovine serum albumin

Jinghua Yu et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2009)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.