4.5 Review

A review of the efforts to develop muscle and musculoskeletal models for biomechanics in the last 50 years

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Article Biophysics

A 3D model of the soleus reveals effects of aponeuroses morphology and material properties on complex muscle fascicle behavior

Katherine R. Knaus et al.

Summary: The study established an image-based finite element model representing the 3D structure of the soleus muscle and its aponeurosis connective tissue, predicting tissue displacements and fascicle architecture changes. The model's initial architecture and changes during passive lengthening were consistent with in vivo data. Model predictions indicated muscle displacements during active lengthening, with average fascicle strains similar between compartments. Further simulations showed how aponeurosis material properties influenced fascicle architecture changes.

JOURNAL OF BIOMECHANICS (2022)

Article Physiology

The Contributions of Extracellular Matrix and Sarcomere Properties to Passive Muscle Stiffness in Cerebral Palsy

Ryan N. Konno et al.

Summary: Cerebral palsy leads to increased skeletal muscle stiffness due to changes in microstructural components, particularly extracellular matrix volume, sarcomere length, and fiber diameter. Experimental studies have shown variability in the degree of alteration, but increased sarcomere length is a consistent finding. Using a three-dimensional modeling approach, this study isolates the individual effects of microstructural alterations on whole muscle behavior and finds that extracellular matrix volume has the largest impact on muscle stiffness.

FRONTIERS IN PHYSIOLOGY (2022)

Article Biophysics

Modeling muscle function using experimentally determined subject-specific muscle properties

J. M. Wakeling et al.

Summary: In this study, rat muscle force data was used to test the accuracy of Hill-type muscle models, with findings indicating that subject-specific intrinsic properties can reduce errors in simulating cyclic contractions. However, there was no improvement in model performance when focusing on specific anatomical regions of the muscle.

JOURNAL OF BIOMECHANICS (2021)

Article Physiology

The Energy of Muscle Contraction. III. Kinetic Energy During Cyclic Contractions

Stephanie A. Ross et al.

Summary: The study found that increasing muscle size leads to higher kinetic energy per unit volume and greater relative energy stored in the aponeurosis. However, this also results in lower mass-specific work output per cycle, particularly with smaller initial pennation angles. The addition of mass in the muscle model causes non-uniform acceleration, indicating that greater mass contributes to tissue non-uniformity in whole muscle behavior.

FRONTIERS IN PHYSIOLOGY (2021)

Article Multidisciplinary Sciences

The energy of muscle contraction. IV. Greater mass of larger muscles decreases contraction efficiency

Stephanie A. Ross et al.

Summary: The study showed that greater muscle mass resulted in lower contraction efficiency primarily due to lower mass-specific mechanical work per cycle. However, adding a tendon in series with the muscle improved mass-specific work and efficiency per cycle despite higher predicted metabolic cost. This study indicates that muscle mass is an important determinant of whole muscle contraction efficiency.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2021)

Article Multidisciplinary Sciences

Task-dependent recruitment across ankle extensor muscles and between mechanical demands is driven by the metabolic cost of muscle contraction

Adrian K. M. Lai et al.

Summary: The study reveals that the nervous system can recruit motor units within muscles and coordinate different muscles by prioritizing minimizing the metabolic cost of muscle contraction during body movement. This strategy allows for adjustments in muscle activity and force distribution based on various mechanical demands, ultimately controlling muscle function effectively.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2021)

Article Engineering, Biomedical

Ultrasound-Based Optimal Parameter Estimation Improves Assessment of Calf Muscle-Tendon Interaction During Walking

T. Delabastita et al.

ANNALS OF BIOMEDICAL ENGINEERING (2020)

Review Physiology

Titin: A Tunable Spring in Active Muscle

Kiisa Nishikawa

PHYSIOLOGY (2020)

Article Biology

Added mass in rat plantaris muscle causes a reduction in mechanical work

Stephanie A. Ross et al.

JOURNAL OF EXPERIMENTAL BIOLOGY (2020)

Review Biophysics

Sarcomere Length Nonuniformity and Force Regulation in Myofibrils and Sarcomeres

Felipe de Souza Leite et al.

BIOPHYSICAL JOURNAL (2020)

Article Biochemical Research Methods

OpenSim Moco: Musculoskeletal optimal control

Christopher L. Dembia et al.

PLOS COMPUTATIONAL BIOLOGY (2020)

Article Physiology

The Energy of Muscle Contraction. II. Transverse Compression and Work

David S. Ryan et al.

FRONTIERS IN PHYSIOLOGY (2020)

Review Physiology

The Multi-Scale, Three-Dimensional Nature of Skeletal Muscle Contraction

Thomas J. Roberts et al.

PHYSIOLOGY (2019)

Article Biology

Transverse anisotropy in the deformation of the muscle during dynamic contractions

Avleen Randhawa et al.

JOURNAL OF EXPERIMENTAL BIOLOGY (2018)

Article Biochemical Research Methods

A modelling approach for exploring muscle dynamics during cyclic contractions

Stephanie A. Ross et al.

PLOS COMPUTATIONAL BIOLOGY (2018)

Article Multidisciplinary Sciences

Geometric models to explore mechanisms of dynamic shape change in skeletal muscle

Taylor J. M. Dick et al.

ROYAL SOCIETY OPEN SCIENCE (2018)

Article Biochemical Research Methods

OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement

Ajay Seth et al.

PLOS COMPUTATIONAL BIOLOGY (2018)

Article Multidisciplinary Sciences

Metabolic cost underlies task-dependent variations in motor unit recruitment

Adrian K. M. Lai et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2018)

Article Engineering, Biomedical

Evaluation of Direct Collocation Optimal Control Problem Formulations for Solving the Muscle Redundancy Problem

Friedl De Groote et al.

ANNALS OF BIOMEDICAL ENGINEERING (2016)

Article Multidisciplinary Sciences

The effect of intramuscular fat on skeletal muscle mechanics: implications for the elderly and obese

Hadi Rahemi et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2015)

Article Biology

Multidimensional models for predicting muscle structure and fascicle pennation

Avleen Randhawa et al.

JOURNAL OF THEORETICAL BIOLOGY (2015)

Article Biophysics

Muscle force depends on the amount of transversal muscle loading

Tobias Siebert et al.

JOURNAL OF BIOMECHANICS (2014)

Article Biophysics

A phenomenological muscle model to assess history dependent effects in human movement

C. P. McGowan et al.

JOURNAL OF BIOMECHANICS (2013)

Article Engineering, Biomedical

A Muscle's Force Depends on the Recruitment Patterns of Its Fibers

James M. Wakeling et al.

ANNALS OF BIOMEDICAL ENGINEERING (2012)

Article Mathematical & Computational Biology

Spreading out Muscle Mass within a Hill-Type Model: A Computer Simulation Study

Michael Guenther et al.

COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2012)

Article Computer Science, Interdisciplinary Applications

A physiology-based inverse dynamic analysis of human gait using sequential convex programming: a comparative study

F. De Groote et al.

COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING (2012)

Article Biophysics

Regional variations in fascicle curvatures within a muscle belly change during contraction

Ana I. L. Namburete et al.

JOURNAL OF BIOMECHANICS (2012)

Article Biology

Is titin a 'winding filament'? A new twist on muscle contraction

Kiisa C. Nishikawa et al.

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2012)

Article Biochemical Research Methods

Elastic Energy Storage and Radial Forces in the Myofilament Lattice Depend on Sarcomere Length

C. David Williams et al.

PLOS COMPUTATIONAL BIOLOGY (2012)

Article Neurosciences

EMG analysis tuned for determining the timing and level of activation in different motor units

Sabrina S. M. Lee et al.

JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY (2011)

Article Biophysics

Optimality principles for model-based prediction of human gait

Marko Ackermann et al.

JOURNAL OF BIOMECHANICS (2010)

Article Computer Science, Interdisciplinary Applications

A physiology based inverse dynamic analysis of human gait: potential and perspectives

F. De Groote et al.

COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING (2009)

Article Biophysics

Does residual force enhancement increase with increasing stretch magnitudes?

Brandon Hisey et al.

JOURNAL OF BIOMECHANICS (2009)

Review Physiology

Motor unit recruitment for dynamic tasks: current understanding and future directions

Emma F. Hodson-Tole et al.

JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY (2009)

Article Computer Science, Interdisciplinary Applications

Micromechanical modelling of skeletal muscles based on the finite element method

Markus Boel et al.

COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING (2008)

Article Multidisciplinary Sciences

Variable gearing in pennate muscles

Emanuel Azizi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Engineering, Multidisciplinary

Dynamic simulation of human motion: numerically efficient inclusion of muscle physiology by convex optimization

Goele Pipeleers et al.

OPTIMIZATION AND ENGINEERING (2008)

Article Engineering, Biomedical

OpenSim: open-source software to create and analyze dynamic Simulations of movement

Scott L. Delp et al.

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING (2007)

Review Radiology, Nuclear Medicine & Medical Imaging

Image-based musculoskeletal modeling: Applications, advances, and future opportunities

Silvia S. Blemker et al.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2007)

Article Biophysics

Three-dimensional finite element modelling of muscle forces during mastication

Oliver Rohrle et al.

JOURNAL OF BIOMECHANICS (2007)

Article Multidisciplinary Sciences

Muscle fibre recruitment can respond to the mechanics of the muscle contraction

James M. Wakeling et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2006)

Article Engineering, Biomedical

Three-dimensional representation of complex muscle architectures and geometries

SS Blemker et al.

ANNALS OF BIOMEDICAL ENGINEERING (2005)

Article Biophysics

A 3D model of muscle reveals the causes of nonuniform strains in the biceps brachii

SS Blemker et al.

JOURNAL OF BIOMECHANICS (2005)

Article Biology

Finite element modelling of contracting skeletal muscle

CWJ Oomens et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES (2003)

Article Biophysics

Generating dynamic simulations of movement using computed muscle control

DG Thelen et al.

JOURNAL OF BIOMECHANICS (2003)

Article Neurosciences

Effects of contraction history on control and stability in explosive actions

GJC Ettema

JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY (2002)

Article Biophysics

Dynamic optimization of human walking

FC Anderson et al.

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME (2001)

Article Biophysics

Musculo-skeletal loading conditions at the hip during walking and stair climbing

MO Heller et al.

JOURNAL OF BIOMECHANICS (2001)

Article Computer Science, Cybernetics

Muscle contraction history: modified Hill versus an exponential decay model

GJC Ettema et al.

BIOLOGICAL CYBERNETICS (2000)

Article Biology

A finite-element model for the mechanical analysis of skeletal muscles

T Johansson et al.

JOURNAL OF THEORETICAL BIOLOGY (2000)