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Functionalization of electrospun nanofiber for biomedical application

期刊

JOURNAL OF APPLIED POLYMER SCIENCE
卷 140, 期 23, 页码 -

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WILEY
DOI: 10.1002/app.53906

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biomedical applications; cancer therapy; drug delivery; nanofibers; tissue engineering; wound healing

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For centuries, nanofibers have been fabricated by converting polymeric materials into nanofibers with tunable properties and have shown great potential in various biomedical applications. In recent years, advances in nanotechnology have enabled the formation of electrospun nanofibers with customizable geometries and release properties. These nanofibers exhibit unique structural characteristics, such as a large surface-to-volume ratio and interconnected pores, which make them suitable for a wide range of healthcare, energy, and environmental applications. This review focuses on the recent advances in electrospun nanofibers for biomedical applications, including therapeutic delivery, tissue engineering, wound healing, and cancer research.
For centuries, nanofibers have been fabricated by converting polymeric materials into nanofibers with tunable mixtures, dimensions, pore structure, and interface properties. Nanofibers include many benefits for transporting drug substances with various biomedical applications. Electrospun nanofibers with customizable geometries and release properties are readily formed due to advances in nanotechnology. The structural characteristics of the electrospun nanofibers/nano yarns are tremendous owing to their large surface-to-volume ratio, interconnected pores, lightweight and permeability, which helps in their wide applications in the health care, energy and environmental aspects of research. The present review focuses on the recent advances in electrospun nanofibers for biomedical applications. Further, this review will examine nanofiber uses in therapeutic delivery and tissue engineering. Additionally, the potential biomedical applications of nanofibers in wound healing and cancer research are reviewed.

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