期刊
INVESTIGATIVE RADIOLOGY
卷 58, 期 10, 页码 746-753出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RLI.0000000000000983
关键词
gadolinium-based contrast agents; artificial intelligence; deep learning; dosage; brain MRI; cardiac MRI
Brain and cardiac MRIs are important noninvasive imaging tools that can provide clinical information. Artificial intelligence has been explored as a method to synthesize virtual contrast MR images without the need for gadolinium-based contrast agents. Further research is needed to make these AI solutions feasible and reliable.
Brain and cardiac MRIs are fundamental noninvasive imaging tools, which can provide important clinical information and can be performed without or with gadolinium-based contrast agents (GBCAs), depending on the clinical indication. It is currently a topic of debate whether it would be feasible to extract information such as standard gadolinium-enhanced MRI while injecting either less or no GBCAs. Artificial intelligence (AI) is a great source of innovation in medical imaging and has been explored as a method to synthesize virtual contrast MR images, potentially yielding similar diagnostic performance without the need to administer GBCAs. If possible, there would be significant benefits, including reduction of costs, acquisition time, and environmental impact with respect to conventional contrast-enhanced MRI examinations. Given its promise, we believe additional research is needed to increase the evidence to make these AI solutions feasible, reliable, and robust enough to be integrated into the clinical framework. Here, we review recent AI studies aimed at reducing or replacing gadolinium in brain and cardiac imaging while maintaining diagnostic image quality.
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