☆ 4.7 Review

Research Progress of Nanomedicine-Based Mild Photothermal Therapy in Tumor

INTERNATIONAL JOURNAL OF NANOMEDICINE (2023)

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Photodynamic therapy induces human esophageal carcinoma cell pyroptosis by targeting the PKM2/caspase-8/caspase-3/GSDME axis

Lisha Li et al.

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A Crystalline Three-Dimensional Covalent Organic Framework with Flexible Building Blocks

Xiaoling Liu et al.

Summary: By incorporating flexible building blocks into the construction of 3D COFs, interesting breathing behavior can be achieved, and smart materials with reversible shape transformation properties can be fabricated.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

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Engineering precision nanoparticles for drug delivery

Michael J. Mitchell et al.

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Single-Atom Catalysts for Nanocatalytic Tumor Therapy

Xiangyu Lu et al.

Summary: This article reviews the latest advances in nanocatalytic tumor therapy, focusing on the remarkable achievements of single-atom catalysts (SACs) in several different treatment modalities, as well as the attention on catalytic nanoplatform construction and catalytic mechanism. Challenges still remain for the future design and engineering of SACs for tumor therapy.

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Summary: Photothermal therapy shows promise in tumor treatment, but has limitations such as light penetration constraints. By combining PTT with chemotherapy using TCPP-Iso combined nanoparticles, synergistic effects in killing cancer cells were achieved at a relatively mild temperature with minimal toxicity to normal tissue cells.

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Which is Better for Nanomedicines: Nanocatalysts or Single-Atom Catalysts?

Mengyang Zhao et al.

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Advances in identification and selection of personalized neoantigen/T-cell pairs for autologous adoptive T cell therapies

Florian Kast et al.

Summary: Personalized adoptive cell therapies (ACT) targeting neoantigens involve identifying suitable personal targets (neoantigens), selecting T cells or their T cell receptors (TCRs) specific for these neoantigens, and expanding the selected T cell population or generating sufficient number of TCR modified T cells. The challenges and approaches to identifying neoantigens and selecting neoantigen-reactive T cells for use in ACT are discussed in this review.

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Synergistic Cancer Photochemotherapy via Layered Double Hydroxide-Based Trimodal Nanomedicine at Very Low Therapeutic Doses

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NIR-Actuated Remote Activation of Ferroptosis in Target Tumor Cells through a Photothermally Responsive Iron-Chelated Biopolymer Nanoplatform

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Hsp90 inhibitor-loaded IR780 micelles for mitochondria-targeted mild-temperature photothermal therapy in xenograft models of human breast cancer

Tao Zhang et al.

Summary: A novel photosensitizer with mitochondrial targeting based on IR780 iodide and a heat shock protein 90 inhibitor (BIIB021) was synthesized, showing promising potential for reducing cell tolerance to heat and enhancing the effect of mitochondria-targeted mild-temperature photothermal therapy.

CANCER LETTERS (2021)

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Article Nanoscience & Nanotechnology

Photothermal nanofibres enable safe engineering of therapeutic cells

Ranhua Xiong et al.

Summary: Photothermal nanofibres embedded with iron oxide nanoparticles can deliver effector macromolecules to different types of cells without causing cellular toxicity or diminishing therapeutic potency, showing promise for safe and efficient production of engineered cells for therapeutic applications.

NATURE NANOTECHNOLOGY (2021)

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Review Biochemistry & Molecular Biology

mRNA vaccine for cancer immunotherapy

Lei Miao et al.

Summary: mRNA vaccines have emerged as a promising platform for cancer immunotherapy, showcasing high potency, safe administration, rapid development potentials, and cost-effective manufacturing. However, challenges such as stability, innate immunogenicity, and inefficient in vivo delivery restrict their applications. In addressing these challenges, structural modifications and formulation methods are being researched to enhance the anti-tumor immune response.

MOLECULAR CANCER (2021)

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Article Chemistry, Multidisciplinary

Nanoengineered CAR-T Biohybrids for Solid Tumor Immunotherapy with Microenvironment Photothermal-Remodeling Strategy

Ze Chen et al.

Summary: This study demonstrates a nanoengineered CAR-T strategy using a nano-photosensitizer to enhance solid tumor therapy by modulating the tumor microenvironment. The engineered CAR-T biohybrids retain the original CAR-T cell activities while possessing fluorescent tracing and microenvironment remodeling abilities, ultimately boosting immunotherapy for solid tumors.

SMALL (2021)

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Article Engineering, Biomedical

Redox responsive nanoparticle encapsulating black phosphorus quantum dots for cancer theranostics

Haolin Chen et al.

Summary: The study developed a biodegradable and biocompatible black phosphorus-based nanoagent for cancer diagnosis and therapy. This nanoagent has excellent photothermal properties and drug delivery capacity, serving as a novel therapeutic platform with low dosage and side effects. Both the polymer and BPQD are degradable, indicating this platform is a rare PT-OCT agent that is completely biodegradable.

BIOACTIVE MATERIALS (2021)

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Article Nanoscience & Nanotechnology

A Nucleic Acid/Gold Nanorod-Based Nanoplatform for Targeted Gene Editing and Combined Tumor Therapy

Wantao Tang et al.

Summary: A facile strategy for constructing an sgRNA/Cas9 complex co-assembled nanoplatform for targeted gene editing and combined tumor therapy was reported. The multifunctional nanoplatform with active cell targeting group and nuclear targeting peptide efficiently internalized and targeted transported, achieving endogenous gene editing of tumor-associated gene PLK1. This multifunctional nanocarrier provides a new strategy for the development of combined tumor therapy.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Engineering, Biomedical

Mild hyperthermia promotes immune checkpoint blockade-based immunotherapy against metastatic pancreatic cancer using size-adjustable nanoparticles

Qianwen Yu et al.

Summary: The combination of mild hyperthermia and immune checkpoint blockade treatment effectively suppressed tumor growth and metastasis; size-adjustable nanoparticles have great potential in improving cancer treatment outcomes.

ACTA BIOMATERIALIA (2021)

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Article Chemistry, Multidisciplinary

A Systematic Strategy of Combinational Blow for Overcoming Cascade Drug Resistance via NIR-Light-Triggered Hyperthermia

Lingna Wang et al.

Summary: A systematic combination strategy utilizing near-infrared light-triggered hyperthermia, combined with cisplatin, was proposed to overcome drug resistance. The strategy showed significant efficacy in inhibiting the growth of multidrug-resistant lung cancer in both in vitro and in vivo studies.

ADVANCED MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Single-Atom Pd Nanozyme for Ferroptosis-Boosted Mild-Temperature Photothermal Therapy

Mengyu Chang et al.

Summary: Photothermal therapy (PTT) is a promising tumor therapeutic modality, but minimizing damage to healthy tissues while maximizing efficiency is crucial. Utilizing a single-atom nanozyme (SAzyme) can improve the effectiveness of mild PTT by promoting ferroptosis.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

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Review Pharmacology & Pharmacy

Nanomedicine potentiates mild photothermal therapy for tumor ablation

Zijun Jiang et al.

Summary: Photothermal therapy has made great progress in non-invasive cancer treatment, with mild temperature PTT showing potential to overcome traditional treatment limitations. However, cancer cells' resistance to heat may lead to insufficient therapy, necessitating synergistic treatments to enhance efficacy.

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

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Article Chemistry, Multidisciplinary

Combination of MAPK inhibition with photothermal therapy synergistically augments the anti-tumor efficacy of immune checkpoint blockade

Xiaowei Liu et al.

Summary: The research demonstrates the advantage of photothermal-targeted-immune triple combinatorial regimen in treating tumors that are clinically unresectable multifocal and lack T-cell infiltration.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Chemistry, Multidisciplinary

NIR-II Absorbing Semiconducting Polymer-Triggered Gene-Directed Enzyme Prodrug Therapy for Cancer Treatment

Xun Zhang et al.

Summary: This study demonstrates the precise regulation of gene-directed enzyme prodrug therapy (GDEPT) for cancer treatment using a near-infrared II (NIR-II) absorbing semiconducting polymer (PBDTQ) to remotely activate the heat-shock protein 70 (HSP70) promoter. By leveraging this approach, noninvasive remote control for treating various types of cancers could be achieved with minimized collateral damage and nontargeted side effects.

SMALL (2021)

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Article Multidisciplinary Sciences

Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors

Baharak Bahmani et al.

Summary: This study explores the potential of using platelet membrane-coated nanoparticles for localized delivery of TLR agonists in tumor immunotherapy. The results demonstrate enhanced local immune activation, complete tumor regression in colorectal tumor models, and protection against tumor re-challenges. Moreover, intratumoral delivery of TLR agonists also shows efficacy in delaying tumor growth and inhibiting metastasis in aggressive breast cancer models.

NATURE COMMUNICATIONS (2021)

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Article Engineering, Biomedical

Enhanced tumour penetration and prolonged circulation in blood of polyzwitterion-drug conjugates with cell-membrane affinity

Siqin Chen et al.

Summary: Conjugates of small-molecule anticancer drugs with a polyzwitterion that has negligible interaction with proteins and weak interaction with phospholipids can effectively eradicate large tumours and patient-derived tumour xenografts in mice by facilitating their transcytosis-mediated extravasation and infiltration into tumours, showcasing potential for translational anticancer nanomedicines.

NATURE BIOMEDICAL ENGINEERING (2021)

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Review Multidisciplinary Sciences

Low-Temperature Photothermal Therapy: Strategies and Applications

Xiulin Yi et al.

Summary: This study summarises strategies for achieving low-temperature PTT using nanomaterials, introduces the synthesis, characteristics, and applications of these nanoplatforms, and discusses the synergistic cancer therapeutic effect of combining PTT with other treatment modalities.

RESEARCH (2021)

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Article Nanoscience & Nanotechnology

1T-Phase Dirac Semimetal PdTe2 Nanoparticles for Efficient Photothermal Therapy in the NIR-II Biowindow

Jingjing Luo et al.

Summary: The study successfully synthesized PdTe2 nanoparticles with excellent photothermal properties, encapsulated in DSPE-PEG to achieve high photothermal conversion efficiency and tumor inhibition effects. Under NIR-II laser irradiation, efficient tumor treatment of NIR-II photothermal nanoagents was achieved.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Nanoscience & Nanotechnology

Self-promoted Albumin-Based Nanoparticles for Combination Therapy against Metastatic Breast Cancer via a Hyperthermia-Induced Platelet Bridge

Wei Zhao et al.

Summary: This study developed a photothermal therapy strategy using activated platelets as bridges to enhance drug delivery efficacy for inhibiting the growth of primary tumors and metastasis in metastatic cancer treatment. By utilizing mitochondrial targeting, platelet targeting, and metastasis-EPR effects, the constructed nanoplatform effectively improved drug accumulation and inhibited tumor growth and metastasis.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Nanoscience & Nanotechnology

Biocompatible Ruthenium Single-Atom Catalyst for Cascade Enzyme-Mimicking Therapy

Wenyu Wang et al.

Summary: This study successfully constructed Ru single-atom enzymes with superior activity and stability by using carbon dots as the carrier material, leading to a lethal effect on cancer cells. The Ru single-atom enzymes exhibit excellent peroxidase-like activity, activating H2O2 to produce reactive oxygen species that cause damage to cancer cells.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Nanoscience & Nanotechnology

Cancer Cytomembrane-Cloaked Prussian Blue Nanoparticles Enhance the Efficacy of Mild-Temperature Photothermal Therapy by Disrupting Mitochondrial Functions of Cancer Cells

Pei Wang et al.

Summary: Researchers have developed a nanosystem for mild-temperature photothermal therapy by using modified nanoparticles, achieving efficient treatment of cancer cells by disrupting ATP production. This innovative approach shows significant potential for various biomedical applications.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Chemistry, Multidisciplinary

Hypoxia-Responsive Gene Editing to Reduce Tumor Thermal Tolerance for Mild-Photothermal Therapy

Xueqing Li et al.

Summary: This study develops a hypoxia-responsive nanocomposite for mild-photothermal therapy through gene editing in tumors. The technology has the potential to enhance tumor ablation efficiency and reduce damage to surrounding healthy tissues.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

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Article Chemistry, Multidisciplinary

A Titanium Nitride Nanozyme for pH-Responsive and Irradiation-Enhanced Cascade-Catalytic Tumor Therapy

Jiaming Liu et al.

Summary: The study found that nitrogen doping significantly enhanced the peroxidase activity of titanium-based nanozymes, and further improved the catalytic activity of nanozymes under near-infrared laser irradiation. By using TLGp, combining pH-responsive GOx-mediated H2O2 self-supply, nitrogen doping, and irradiation-enhanced enzymatic activity of titanium nitride nanoparticles, along with mild photothermal therapy, effective tumor inhibition with minimal side effects in vivo was achieved.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

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Article Engineering, Biomedical

NIR-II fluorescence imaging guided tumor-specific NIR-II photothermal therapy enhanced by starvation mediated thermal sensitization strategy

Yeneng Dai et al.

Summary: The study proposed a tumor-specific enhanced NIR-II PTT strategy through starvation-mediated thermal sensitization, using a semiconducting polymer and glycolysis inhibitor 2DG encapsulated into folate modified liposomes. By targeting and triggering NIR-II photothermal effect, spatial-temporal release of 2DG was achieved and enhanced the tumor thermal sensitivity towards PTT.

BIOMATERIALS (2021)

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Article Chemistry, Multidisciplinary

Heat/pH-boosted release of 5-fluorouracil and albumin-bound paclitaxel from Cu-doped layered double hydroxide nanomedicine for synergistical chemo-photo-therapy of breast cancer

Jianping Liu et al.

Summary: A novel nanomedicine has been developed for combination breast cancer therapy, which shows high efficacy in nearly eliminating tumors with minimal side effects.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Chemistry, Multidisciplinary

Controlled CRISPR-Cas9 Ribonucleoprotein Delivery for Sensitized Photothermal Therapy

Chao Chen et al.

Summary: A near-infrared light-triggered thermo-responsive copper sulfide multifunctional nanotherapeutic platform was developed for controlled release of CRISPR-Cas9 ribonucleoprotein and doxorubicin, showing potential for synergistic combination therapy in cancer treatment.

SMALL (2021)

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Article Chemistry, Multidisciplinary

NIR-II Excitation Phototheranostic Nanomedicine for Fluorescence/Photoacoustic Tumor Imaging and Targeted Photothermal-Photonic Thermodynamic Therapy

Yeneng Dai et al.

Summary: This study presents a second near infrared light excitation phototheranostic nanomedicine for the treatment of triple-negative breast cancer, integrating multiple functional components for precise diagnosis and effective therapy through targeting, localization, and multimodal imaging.

SMALL (2021)

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Article Engineering, Biomedical

Multifunctional Hybrid Hydrogel Enhanced Antitumor Therapy through Multiple Destroying DNA Functions by a Triple-Combination Synergistic Therapy

Jiamin Zhang et al.

Summary: A multifunctional hybrid hydrogel has been developed for efficient cancer therapy by damaging DNA self-repair functions and enhancing the therapeutic effects of brachytherapy.

ADVANCED HEALTHCARE MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Enzyme-Loaded pH-Sensitive Photothermal Hydrogels for Mild-temperature-mediated Combinational Cancer Therapy

Jindong Xia et al.

Summary: This study introduces a constructed hydrogel with a pH-sensitive photothermal effect for combinational cancer therapy, releasing GOx to consume glucose in tumors and suppressing heat shock protein expression to enable mild NIR-II PTT. The method not only inhibits tumor growth significantly in a breast cancer murine model but also completely prevents lung metastasis.

FRONTIERS IN CHEMISTRY (2021)

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Article Chemistry, Multidisciplinary

Two step promotion of a hot tumor immune environment by gold decorated iron oxide nanoflowers and light-triggered mild hyperthermia

Alba Nicolas-Boluda et al.

Summary: This study reveals that gold decorated iron oxide nanoflowers (GIONF) can significantly impact the tumor immune environment, promoting recruitment of monocytes and creating a pro-inflammatory anti-tumor microenvironment. Furthermore, mild hyperthermia treatment also leads to an increase in CD8+ T lymphocytes and pro-inflammatory cytokines in addition to GIONF effects.

NANOSCALE (2021)

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Article Materials Science, Biomaterials

Covalent organic framework based nanoagent for enhanced mild-temperature photothermal therapy

Qiaoqiao Sun et al.

Summary: A nanoagent called COF-GA was designed to enhance photothermal therapy against cancer at low temperatures by inhibiting HSP90, effectively killing tumor cells. The agent can increase the temperature of tumor tissue under laser irradiation, leading to significant suppression of tumor growth.

BIOMATERIALS SCIENCE (2021)

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Article Medicine, Research & Experimental

A platelet-mimicking theranostic platform for cancer interstitial brachytherapy

Meng Lyu et al.

Summary: This study developed a biomimetic nanotheranostic platform to enhance the efficacy of interstitial brachytherapy (BT) for cancer. By utilizing the targeting capabilities of nanoparticles, the treatment successfully evaded immune clearance and specifically accumulated in tumor tissues, resulting in improved therapeutic outcomes.

THERANOSTICS (2021)

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Article Chemistry, Multidisciplinary

A multifunctional nanodiamond-based nanoplatform for the enhanced mild-temperature photothermal/chemo combination therapy of triple negative breast cancer via an autophagy regulation strategy

Xinyue Cui et al.

Summary: This study demonstrated the construction of a nanodiamond-based nanoplatform for enhanced mild-temperature photothermal/chemo combination therapy against TNBC by inhibiting autophagy, which could weaken therapeutic resistance and improve anti-tumor efficacy both in vitro and in vivo. Additionally, the nanoplatform could be used for fluorescence and photoacoustic imaging, showing its potential as a theranostic tool.

NANOSCALE (2021)

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Article Medicine, Research & Experimental

Silicon nanowires decorated with platinum nanoparticles were applied for photothermal-enhanced sonodynamic therapy

Lina Sun et al.

Summary: The developed Si-Pt NCs exhibit strong sonodynamic therapy and chemodynamic therapy effects, with a higher therapeutic efficacy. Taking advantage of the mesoporous structure, the mild photothermal effect further enhances the combined cancer therapy of SDT and CDT provided by Si-Pt NCs.

THERANOSTICS (2021)

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Article Nanoscience & Nanotechnology

Ultrafast Low-Temperature Photothermal Therapy Activates Autophagy and Recovers Immunity for Efficient Antitumor Treatment

Xiangyu Deng et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Nanoscience & Nanotechnology

Virus-Like Fe3O4@Bi2S3 Nanozymes with Resistance-Free Apoptotic Hyperthermia-Augmented Nanozymitic Activity for Enhanced Synergetic Cancer Therapy

Yajie Zhao et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Engineering, Biomedical

Mitochondria-acting nanomicelles for destruction of cancer cells via excessive mitophagy/autophagy-driven lethal energy depletion and phototherapy

Ya-Xuan Zhu et al.

BIOMATERIALS (2020)

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Article Engineering, Biomedical

Dual-stimuli responsive nanotheranostics for mild hyperthermia enhanced inhibition of Wnt/β-catenin signaling

Tao Feng et al.

BIOMATERIALS (2020)

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Review Biotechnology & Applied Microbiology

The approved gene therapy drugs worldwide: from 1998 to 2019

Cui-Cui Ma et al.

BIOTECHNOLOGY ADVANCES (2020)

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Article Chemistry, Multidisciplinary

Reactive Oxygen Correlated Chemiluminescent Imaging of a Semiconducting Polymer Nanoplatform for Monitoring Chemodynamic Therapy

Youjuan Wang et al.

NANO LETTERS (2020)

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Review Cell Biology

Ferroptosis: past, present and future

Jie Li et al.

CELL DEATH & DISEASE (2020)

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Article Nanoscience & Nanotechnology

Brome mosaic virus-like particles as siRNA nanocarriers for biomedical purposes

Alfredo Nunez-Rivera et al.

BEILSTEIN JOURNAL OF NANOTECHNOLOGY (2020)

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Review Pharmacology & Pharmacy

Nanoparticle cancer vaccines: Design considerations and recent advances

Jingjing Liu et al.

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

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Article Chemistry, Multidisciplinary

A Heterojunction Structured WO2.9-WSe2 Nanoradiosensitizer Increases Local Tumor Ablation and Checkpoint Blockade Immunotherapy upon Low Radiation Dose

Xinghua Dong et al.

ACS NANO (2020)

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Article Chemistry, Multidisciplinary

A Porous Au@Rh Bimetallic Core-Shell Nanostructure as an H2O2-Driven Oxygenerator to Alleviate Tumor Hypoxia for Simultaneous Bimodal Imaging and Enhanced Photodynamic Therapy

Jinping Wang et al.

ADVANCED MATERIALS (2020)

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Article Materials Science, Biomaterials

Low-Temperature Trigger Nitric Oxide Nanogenerators for Enhanced Mild Photothermal Therapy

Chaoqun You et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

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Article Chemistry, Multidisciplinary

Hyperthermia-Triggered On-Demand Biomimetic Nanocarriers for Synergetic Photothermal and Chemotherapy

Gao Junbin et al.

ADVANCED SCIENCE (2020)

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Article Nanoscience & Nanotechnology

Fever-Inducible Lipid Nanocomposite for Boosting Cancer Therapy through Synergistic Engineering of a Tumor Microenvironment

Ding Qu et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Review Pharmacology & Pharmacy

Dancing with reactive oxygen species generation and elimination in nanotheranostics for disease treatment

Zijian Zhou et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

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Article Engineering, Biomedical

Polydopamine-coated nucleic acid nanogel for siRNA-mediated low-temperature photothermal therapy

Fei Ding et al.

BIOMATERIALS (2020)

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Article Biotechnology & Applied Microbiology

Biodegradable hollow mesoporous organosilica nanotheranostics (HMON) for multi-mode imaging and mild photo-therapeutic-induced mitochondrial damage on gastric cancer

Weihong Guo et al.

JOURNAL OF NANOBIOTECHNOLOGY (2020)

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Article Chemistry, Multidisciplinary

Smart gold nanocages for mild heat -triggered drug release and breaking chemoresistance

Huamei He et al.

JOURNAL OF CONTROLLED RELEASE (2020)

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Article Chemistry, Multidisciplinary

A Glucose/Oxygen-Exhausting Nanoreactor for Starvation- and Hypoxia-Activated Sustainable and Cascade Chemo-Chemodynamic Therapy

Yuxin Guo et al.

SMALL (2020)

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Article Multidisciplinary Sciences

Preparation of TiH1.924 nanodots by liquid-phase exfoliation for enhanced sonodynamic cancer therapy

Fei Gong et al.

NATURE COMMUNICATIONS (2020)

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Article Nanoscience & Nanotechnology

Enhanced radiotherapy using photothermal therapy based on dual-sensitizer of gold nanoparticles with acid-induced aggregation

Yumin Zhang et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2020)

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Article Multidisciplinary Sciences

Preparation of parenteral nanocrystal suspensions of etoposide from the excipient free dry state of the drug to enhance in vivo antitumoral properties

Brice Martin et al.

SCIENTIFIC REPORTS (2020)

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Article Materials Science, Biomaterials

A multimodal imaging-guided nanoreactor for cooperative combination of tumor starvation and multiple mechanism-enhanced mild temperature phototherapy

Jin Cao et al.

BIOMATERIALS SCIENCE (2020)

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Article Chemistry, Multidisciplinary

Mitochondria-targeting NO gas nanogenerator for augmenting mild photothermal therapy in the NIR-II biowindow

Canchen Wu et al.

CHEMICAL COMMUNICATIONS (2020)

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Review Immunology

A guide to cancer immunotherapy: from T cell basic science to clinical practice

Alex D. Waldman et al.

NATURE REVIEWS IMMUNOLOGY (2020)

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Article Chemistry, Multidisciplinary

NIR-controlled HSP90 inhibitor release from hollow mesoporous nanocarbon for synergistic tumor photothermal therapy guided by photoacoustic imaging

Jiaxin Sun et al.

NANOSCALE (2020)

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Article Materials Science, Biomaterials

Mild-heat-inducible sequentially released liposomal complex remodels the tumor microenvironment and reinforces anti-breast-cancer therapy

Yue Qin et al.

BIOMATERIALS SCIENCE (2020)

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Review Chemistry, Multidisciplinary

Two-dimensional covalent organic frameworks with hierarchical porosity

Rong-Ran Liang et al.

CHEMICAL SOCIETY REVIEWS (2020)

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Article Materials Science, Biomaterials

Ultralow-intensity near infrared light synchronously activated collaborative chemo/photothermal/photodynamic therapy

Renlu Han et al.

BIOMATERIALS SCIENCE (2020)

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Review Chemistry, Multidisciplinary

Multifunctional sonosensitizers in sonodynamic cancer therapy

Subin Son et al.

CHEMICAL SOCIETY REVIEWS (2020)

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Review Chemistry, Multidisciplinary

Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer

Yijing Liu et al.

CHEMICAL SOCIETY REVIEWS (2019)

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Review Biotechnology & Applied Microbiology

Gene therapy targeting haematopoietic stem cells for inherited diseases: progress and challenges

Marina Cavazzana et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

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Article Chemistry, Multidisciplinary

Water-Dispersible Candle Soot-Derived Carbon Nano-Onion Clusters for Imaging-Guided Photothermal Cancer Therapy

Wei Sun et al.

SMALL (2019)

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Article Multidisciplinary Sciences

Facile syntheses of conjugated polymers for photothermal tumour therapy

Peiyao Chen et al.

NATURE COMMUNICATIONS (2019)

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Article Biotechnology & Applied Microbiology

Smart nanoplatform for sequential drug release and enhanced chemo-thermal effect of dual drug loaded gold nanorod vesicles for cancer therapy

Falian Zhu et al.

JOURNAL OF NANOBIOTECHNOLOGY (2019)

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Article Chemistry, Multidisciplinary

Divergent Synthesis of Chiral Covalent Organic Frameworks

Li-Ke Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Review Biochemistry & Molecular Biology

Modulatory effects of curcumin on heat shock proteins in cancer: A promising therapeutic approach

Fatemeh Forouzanfar et al.

BIOFACTORS (2019)

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Article Engineering, Biomedical

Melanin-like nanoparticles decorated with an autophagy-inducing peptide for efficient targeted photothermal therapy

Zhengjie Zhou et al.

BIOMATERIALS (2019)

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Article Chemistry, Multidisciplinary

Photothermal therapy mediated by phase-transformation nanoparticles facilitates delivery of anti-PD1 antibody and synergizes with antitumor immunotherapy for melanoma

Ni Zhang et al.

JOURNAL OF CONTROLLED RELEASE (2019)

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Article Chemistry, Multidisciplinary

A Multifunctional Biodegradable Nanocomposite for Cancer Theranostics

Jianrong Wu et al.

ADVANCED SCIENCE (2019)

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Article Nanoscience & Nanotechnology

InSe Nanosheets for Efficient NIR-II-Responsive Drug Release

Chi Huang et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

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Article Chemistry, Multidisciplinary

Nanoclustered Cascaded Enzymes for Targeted Tumor Starvation and Deoxygenation-Activated Chemotherapy without Systemic Toxicity

Yinchu Ma et al.

ACS NANO (2019)

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Article Pharmacology & Pharmacy

pH-activated heat shock protein inhibition and radical generation enhanced NIR luminescence imaging-guided photothermal tumour ablation

Shuang Wang et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Article Chemistry, Multidisciplinary

NIR-Responsive Polypeptide Nanocomposite Generates NO Gas, Mild Photothermia, and Chemotherapy to Reverse Multidrug-Resistant Cancer

Yue Ding et al.

NANO LETTERS (2019)

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Article Biotechnology & Applied Microbiology

Mesoporous gold nanoparticles for photothermal controlled anticancer drug delivery

Lingling Zhang et al.

NANOMEDICINE (2019)

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Article Nanoscience & Nanotechnology

Enzyme-activatable polymer-drug conjugate augments tumour penetration and treatment efficacy

Quan Zhou et al.

NATURE NANOTECHNOLOGY (2019)

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Article Chemistry, Multidisciplinary

Molecular Targeting-Mediated Mild-Temperature Photothermal Therapy with a Smart Albumin-Based Nanodrug

Ge Gao et al.

SMALL (2019)

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Article Multidisciplinary Sciences

Bioinspired lipoproteins-mediated photothermia remodels tumor stroma to improve cancer cell accessibility of second nanoparticles

Tao Tan et al.

NATURE COMMUNICATIONS (2019)

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Article Engineering, Biomedical

Biomodal Tumor-Targeted and Redox-Responsive Bi2Se3 Hollow Nanocubes for MSOT/CT Imaging Guided Synergistic Low-Temperature Photothermal Radiotherapy

Yilin Song et al.

ADVANCED HEALTHCARE MATERIALS (2019)

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Article Chemistry, Multidisciplinary

被撤回的出版物: Nanoscale Metal-Organic Framework Mediates Radical Therapy to Enhance Cancer Immunotherapy (Retracted article. See vol. 9, pg. 755, 2023)

Kaiyuan Ni et al.

CHEM (2019)

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Article Nanoscience & Nanotechnology

Localized Free Radicals Burst Triggered by NIR-II Light for Augmented Low-Temperature Photothermal Therapy

Boshu Ouyang et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

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Article Chemistry, Multidisciplinary

Construction of Dually Responsive Nanotransformers with Nanosphere-Nanofiber-Nanosphere Transition for Overcoming the Size Paradox of Anticancer Nanodrugs

Hao-Ran Jia et al.

ACS NANO (2019)

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Article Chemistry, Multidisciplinary

Nanoscale Covalent Organic Framework for Combinatorial Antitumor Photodynamic and Photothermal Therapy

Qun Guan et al.

ACS NANO (2019)

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Article Chemistry, Multidisciplinary

Mo2C-Derived Polyoxometalate for NIR-II Photoacoustic Imaging-Guided Chemodynamic/Photothermal Synergistic Therapy

Gongyuan Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Article Engineering, Biomedical

Bismuth embedded silica nanoparticles loaded with autophagy suppressant to promote photothermal therapy

Tong Chen et al.

BIOMATERIALS (2019)

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Article Multidisciplinary Sciences

Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy

Liping Huang et al.

NATURE COMMUNICATIONS (2019)

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Article Chemistry, Multidisciplinary

Multifunctional Two-Dimensional Core-Shell MXene@Gold Nanocomposites for Enhanced Photo-Radio Combined Therapy in the Second Biological Window

Wantao Tang et al.

ACS NANO (2019)

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Article Engineering, Biomedical

Near-infrared light-controllable on-demand antibiotics release using thermo-sensitive hydrogel-based drug reservoir for combating bacterial infection

Ge Gao et al.

BIOMATERIALS (2019)

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Review Biochemistry & Molecular Biology

Hsp90 and Hsp70 chaperones: Collaborators in protein remodeling

Olivier Genest et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

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Review Materials Science, Biomaterials

Production, surface modification and biomedical applications of nanodiamonds: A sparkling tool for theranostics

Hussain Tinwala et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

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Review Biotechnology & Applied Microbiology

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

Jerome Galon et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

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Review Biotechnology & Applied Microbiology

Delivery technologies for cancer immunotherapy

Rachel S. Riley et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

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Article Medicine, General & Internal

Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Stephen J. Schuster et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Article Chemistry, Multidisciplinary

Efficient Near Infrared Light Triggered Nitric Oxide Release Nanocomposites for Sensitizing Mild Photothermal Therapy

Xiao Zhang et al.

ADVANCED SCIENCE (2019)

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Article Nanoscience & Nanotechnology

Biocompatible Heat-Shock Protein Inhibitor-Delivered Flowerlike Short-Wave Infrared Nanoprobe for Mild Temperature-Driven Highly Efficient Tumor Ablation

Anqi Jiang et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

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Article Chemistry, Multidisciplinary

Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells

Qian Chen et al.

ADVANCED MATERIALS (2019)

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Article Nanoscience & Nanotechnology

DL-Menthol Loaded Polypyrrole Nanoparticles as a Controlled Diclofenac Delivery Platform for Sensitizing Cancer Cells to Photothermal Therapy

Yan Ma et al.

ACS APPLIED BIO MATERIALS (2019)

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Article Materials Science, Biomaterials

Achieving traceless ablation of solid tumors without recurrence by mild photothermal-chemotherapy of triple stimuli-responsive polymer-drug conjugate nanoparticles

Chang Du et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

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Article Medicine, Research & Experimental

A near-infrared light-controlled smart nanocarrier with reversible polypeptide-engineered valve for targeted fluorescence-photoacoustic bimodal imaging-guided chemo-photothermal therapy

Cheng Li et al.

THERANOSTICS (2019)

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Article Materials Science, Biomaterials

Dual drug-paired polyprodrug nanotheranostics reverse multidrug resistant cancers via mild photothermal-cocktail chemotherapy

Chang Du et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

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Article Chemistry, Multidisciplinary

Upconversion-mediated ZnFe2O4 nanoplatform for NIR-enhanced chemodynamic and photodynamic therapy

Shuming Dong et al.

CHEMICAL SCIENCE (2019)

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Review Cell Biology

Regulation of heat shock transcription factors and their roles in physiology and disease

Rocio Gomez-Pastor et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

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Article Nanoscience & Nanotechnology

Intelligent MoS2 Nanotheranostic for Targeted and Enzyme-/pH-/NIR-Responsive Drug Delivery To Overcome Cancer Chemotherapy Resistance Guided by PET Imaging

Xinghua Dong et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

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Article Chemistry, Multidisciplinary

All-in-One Theranostic Nanoagent with Enhanced Reactive Oxygen Species Generation and Modulating Tumor Microenvironment Ability for Effective Tumor Eradication

Yang Liu et al.

ACS NANO (2018)

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Review Chemistry, Multidisciplinary

Stimuli-Responsive NO Release for On-Demand Gas-Sensitized Synergistic Cancer Therapy

Wenpei Fan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

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Review Engineering, Biomedical

Overcoming obstacles in the tumor microenvironment: Recent advancements in nanoparticle delivery for cancer theranostics

Marta Overchuk et al.

BIOMATERIALS (2018)

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Review Oncology

The Platelet Lifeline to Cancer: Challenges and Opportunities

Monika Haemmerle et al.

CANCER CELL (2018)

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Review Chemistry, Multidisciplinary

Catalytic chemistry of glucose oxidase in cancer diagnosis and treatment

Lian-Hua Fu et al.

CHEMICAL SOCIETY REVIEWS (2018)

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Article Chemistry, Multidisciplinary

Biodegradable MoOx nanoparticles with efficient near-infrared photothermal and photodynamic synergetic cancer therapy at the second biological window

Wenyan Yin et al.

NANOSCALE (2018)

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Review Multidisciplinary Sciences

CAR T cell immunotherapy for human cancer

Carl H. June et al.

SCIENCE (2018)

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Review Multidisciplinary Sciences

Cancer immunotherapy using checkpoint blockade

Antoni Ribas et al.

SCIENCE (2018)

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Article Chemistry, Multidisciplinary

Synergized Multimodal Therapy for Safe and Effective Reversal of Cancer Multidrug Resistance Based on Low-Level Photothermal and Photodynamic Effects

Luming Xu et al.

SMALL (2018)

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Article Oncology

A correlation study of fluorouracil pharmacodynamics with clinical efficacy and toxicity

Ece Esin et al.

TUMORI JOURNAL (2018)

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Article Medicine, Research & Experimental

Mesoporous Carbon Nanospheres as a Multifunctional Carrier for Cancer Theranostics

Libo Zhou et al.

THERANOSTICS (2018)

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Article Materials Science, Biomaterials

Platinum nanoworms for imaging-guided combined cancer therapy in the second near-infrared window

Qingxi Ma et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

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Article Pharmacology & Pharmacy

Gold nanorods together with HSP inhibitor-VER-155008 micelles for colon cancer mild-temperature photothermal therapy

Xichuan Tang et al.

ACTA PHARMACEUTICA SINICA B (2018)

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Article Oncology

A correlation study of fluorouracil pharmacodynamics with clinical efficacy and toxicity

Ece Esin et al.

TUMORI JOURNAL (2018)

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Article Engineering, Biomedical

Multifunctional melanin-like nanoparticles for bone-targeted chemo-photothermal therapy of malignant bone tumors and osteolysis

Yitong Wang et al.

BIOMATERIALS (2018)

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Review Chemistry, Multidisciplinary

Predicting the impact of structural diversity on the performance of nanodiamond drug carriers

A. S. Barnard

NANOSCALE (2018)

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Article Multidisciplinary Sciences

Hyperthermia induces therapeutic effectiveness and potentiates adjuvant therapy with non-targeted and targeted drugs in an in vitro model of human malignant melanoma

T. Mantso et al.

SCIENTIFIC REPORTS (2018)

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Article Engineering, Biomedical

Bi2S3-Tween 20 Nanodots Loading PI3K Inhibitor, LY294002, for Mild Photothermal Therapy of LoVo Cells In Vitro and In Vivo

Li Song et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Article Materials Science, Biomaterials

A chloroquine-loaded Prussian blue platform with controllable autophagy inhibition for enhanced photothermal therapy

Yan Ma et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

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Review Medicine, General & Internal

DNA repair pathways and cisplatin resistance: an intimate relationship

Clarissa Ribeiro Reily Rocha et al.

CLINICS (2018)

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Article Chemistry, Multidisciplinary

Crosslinked self-assembled nanoparticles for chemo-sonodynamic combination therapy favoring antitumor, antimetastasis management and immune responses

Mengrui Liu et al.

JOURNAL OF CONTROLLED RELEASE (2018)

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Review Oncology

Role of platelets and platelet receptors in cancer metastasis

Martin Schlesinger

JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)

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Article Multidisciplinary Sciences

Nanodiamond autophagy inhibitor allosterically improves the arsenical-based therapy of solid tumors

Zhifen Cui et al.

NATURE COMMUNICATIONS (2018)

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Article Multidisciplinary Sciences

Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy

Kaiyuan Ni et al.

NATURE COMMUNICATIONS (2018)

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Review Oncology

Revisiting the role of ABC transporters in multidrug-resistant cancer

Robert W. Robey et al.

NATURE REVIEWS CANCER (2018)

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Article Cell Biology

NUPR1 maintains autolysosomal efflux by activating SNAP25 transcription in cancer cells

Yanchao Mu et al.

AUTOPHAGY (2018)

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Review Immunology

Towards personalized, tumour-specific, therapeutic vaccines for cancer

Zhuting Hu et al.

NATURE REVIEWS IMMUNOLOGY (2018)

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Article Immunology

Improving immune-vascular crosstalk for cancer immunotherapy

Yuhui Huang et al.

NATURE REVIEWS IMMUNOLOGY (2018)

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Article Chemistry, Multidisciplinary

A mitochondria-targeting photothermogenic nanozyme for MRI-guided mild photothermal therapy

Kangqiang Qiu et al.

CHEMICAL COMMUNICATIONS (2018)

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Review Cell Biology

Autophagy pathway: Cellular and molecular mechanisms

Li Yu et al.

AUTOPHAGY (2018)

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Article Chemistry, Multidisciplinary

Facile Supramolecular Approach to Nucleic-Acid-Driven Activatable Nanotheranostics That Overcome Drawbacks of Photodynamic Therapy

Xingshu Li et al.

ACS NANO (2018)

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Review Oncology

Circulating and disseminated tumour cells - mechanisms of immune surveillance and escape

Malte Mohme et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2017)

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Review Materials Science, Biomaterials

Two-dimensional transition metal dichalcogenide nanomaterials for combination cancer therapy

Linji Gong et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

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Review Oncology

Cancer nanomedicine: progress, challenges and opportunities

Jinjun Shi et al.

NATURE REVIEWS CANCER (2017)

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Article Engineering, Biomedical

Autophagy inhibition enabled efficient photothermal therapy at a mild temperature

Zhengjie Zhou et al.

BIOMATERIALS (2017)

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Article Oncology

Prediction of severe toxicity in adult patients under treatment with 5-fluorouracil: a prospective cohort study

Carolina Vazquez et al.

ANTI-CANCER DRUGS (2017)

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Review Oncology

Targeting autophagy in cancer

Jean M. Mulcahy Levy et al.

NATURE REVIEWS CANCER (2017)

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Review Chemistry, Multidisciplinary

Cellular uptake of nanoparticles: journey inside the cell

Shahed Behzadi et al.

CHEMICAL SOCIETY REVIEWS (2017)

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Review Biochemistry & Molecular Biology

Molecular definitions of autophagy and related processes

Lorenzo Galluzzi et al.

EMBO JOURNAL (2017)

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Review Biochemistry & Molecular Biology

Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future

Nicholas McGranahan et al.

CELL (2017)

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Article Chemistry, Multidisciplinary

Overcoming the Heat Endurance of Tumor Cells by Interfering with the Anaerobic Glycolysis Metabolism for Improved Photothermal Therapy

Wei-Hai Chen et al.

ACS NANO (2017)

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Article Chemistry, Multidisciplinary

Gold-Nanoclustered Hyaluronan Nano-Assemblies for Photothermally Maneuvered Photodynamic Tumor Ablation

Hwa Seung Han et al.

ACS NANO (2016)

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Article Chemistry, Multidisciplinary

Continuous Cavitation Designed for Enhancing Radiofrequency Ablation via a Special Radiofrequency Solidoid Vaporization Process

Kun Zhang et al.

ACS NANO (2016)

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Article Chemistry, Multidisciplinary

A Multifunctional Platform for Tumor Angiogenesis-Targeted Chemo-Thermal Therapy Using Polydopamine-Coated Gold Nanorods

Lu Zhang et al.

ACS NANO (2016)

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Article Chemistry, Multidisciplinary

Mild Hyperthermia Induced by Gold Nanorod-Mediated Plasmonic Photothermal Therapy Enhances Transduction and Replication of Oncolytic Adenoviral Gene Delivery

Bo-Kyeong Jung et al.

ACS NANO (2016)

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Article Chemistry, Multidisciplinary

Gd-Hybridized Plasmonic Au-Nanocomposites Enhanced Tumor-Interior Drug Permeability in Multimodal Imaging-Guided Therapy

Jing Wang et al.

ADVANCED MATERIALS (2016)

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Article Oncology

Cancer treatment and survivorship statistics, 2016

Kimberly D. Miller et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2016)

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Article Oncology

Cetuximab delivery and antitumor effects are enhanced by mild hyperthermia in a xenograft mouse model of pancreatic cancer

Ryoichi Miyamoto et al.

CANCER SCIENCE (2016)

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Article Oncology

Enterocutaneous fistula in patients with peritoneal malignancy following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: Incidence, management and outcomes

Sarah J. Valle et al.

SURGICAL ONCOLOGY-OXFORD (2016)

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Article Medicine, Research & Experimental

Novel Cs-Based Upconversion Nanoparticles as Dual-Modal CT and UCL Imaging Agents for Chemo-Photothermal Synergistic Therapy

Yuxin Liu et al.

THERANOSTICS (2016)

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Article Engineering, Biomedical

Multifunctional WS2@Poly(ethylene imine) Nanoplatforms for Imaging Guided Gene-Photothermal Synergistic Therapy of Cancer

Chunfang Zhang et al.

ADVANCED HEALTHCARE MATERIALS (2016)

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Review Oncology

Targeting metastasis

Patricia S. Steeg

NATURE REVIEWS CANCER (2016)

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Article Chemistry, Multidisciplinary

Self-Assembled Autophagy-Inducing Polymeric Nanoparticles for Breast Cancer Interference In-Vivo

Yi Wang et al.

ADVANCED MATERIALS (2015)

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Article Chemistry, Multidisciplinary

NIR-Responsive On-Demand Release of CO from Metal Carbonyl-Caged Graphene Oxide Nanomedicine

Qianjun He et al.

ADVANCED MATERIALS (2015)

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Review Hematology

Platelets at the interface of thrombosis, inflammation, and cancer

Aime T. Franco et al.

BLOOD (2015)

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Article Chemistry, Multidisciplinary

MSN-Mediated Sequential Vascular-to-Cell Nuclear-Targeted Drug Delivery for Efficient Tumor Regression

Limin Pan et al.

ADVANCED MATERIALS (2014)

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Article Chemistry, Multidisciplinary

Passive versus Active Tumor Targeting Using RGD- and NGR-Modified Polymeric Nanomedicines

Sijumon Kunjachan et al.

NANO LETTERS (2014)

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Review Oncology

Therapeutic vaccines for cancer: an overview of clinical trials

Ignacio Melero et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2014)

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Article Multidisciplinary Sciences

Platelets guide the formation of early metastatic niches

Myriam Labelle et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

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Review Oncology

Drug Resistance in Cancer: An Overview

Genevieve Housman et al.

CANCERS (2014)

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Article Cell Biology

Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis

Andrija Finka et al.

CELL STRESS & CHAPERONES (2013)

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Review Oncology

Development of artemisinin compounds for cancer treatment

Henry C. Lai et al.

INVESTIGATIONAL NEW DRUGS (2013)

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Article Oncology

Adenovirus-mediated tissue-targeted expression of the CDglyTk gene for the treatment of breast cancer

Guo-qiang Su et al.

MOLECULAR MEDICINE REPORTS (2012)

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Review Biochemistry & Molecular Biology

Molecular mechanisms of cisplatin resistance

L. Galluzzi et al.

ONCOGENE (2012)

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Review Oncology

DNA repair dysregulation from cancer driver to therapeutic target

Nicola J. Curtin

NATURE REVIEWS CANCER (2012)

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Article Oncology

Toward Curative Treatment of Peritoneal Carcinomatosis From Nonovarian Origin by Cytoreductive Surgery Combined With Perioperative Intraperitoneal Chemotherapy A Multi-Institutional Study of 1290 Patients

Olivier Glehen et al.

CANCER (2010)

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Review Biochemistry & Molecular Biology

The Heat Shock Response: Life on the Verge of Death

Klaus Richter et al.

MOLECULAR CELL (2010)

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Review Biochemistry & Molecular Biology

The Molecular Mechanism of Action of Artemisinin-The Debate Continues

Paul M. O'Neill et al.

MOLECULES (2010)

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Review Biotechnology & Applied Microbiology

Targeting mitochondria for cancer therapy

Simone Fulda et al.

NATURE REVIEWS DRUG DISCOVERY (2010)

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Article Multidisciplinary Sciences

Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis

L Borsig et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

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Review Oncology

Role of the heat shock response and molecular chaperones in oncogenesis and cell death

C Jolly et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)

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