4.7 Article

Immunosuppressive Polymeric Nanoparticles Targeting Dendritic Cells Alleviate Lupus Disease in Fcgr2b-/- Mice by Mediating Antigen-Specific Immune Tolerance

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Immunology

PD-1 and ICOS counter-regulate tissue resident regulatory T cell development and IL-10 production during flu

Michael C. McGee et al.

Summary: This study characterized the development and molecular features of tissue resident regulatory T cells (TR-Treg cells) during repetitive heterosubtypic influenza infections. The results showed that lung tissue resident Treg cells accumulated and expressed high levels of co-inhibitory and co-stimulatory receptors after primary and secondary infections. The PD-1 and ICOS signaling pathways counter-regulated the expansion and IL-10 production of TR-Treg cells during secondary influenza infection. Furthermore, the virus-specific TR-Treg cell response displayed distinct kinetics compared to conventional CD4(+) tissue resident memory T cells during secondary flu infection.

FRONTIERS IN IMMUNOLOGY (2022)

Article Chemistry, Multidisciplinary

Effective gene delivery into primary dendritic cells using synthesized PDMAEMA-iron oxide nanocubes

C. Saengruengrit et al.

Summary: The study developed a gene delivery system using magnetic iron oxide nanocubes (MCs) coated with cationic polymer to target primary dendritic cells, demonstrating efficient gene delivery and promising potential for cell-based immunotherapy.

MATERIALS TODAY CHEMISTRY (2021)

Review Nanoscience & Nanotechnology

Inducing immune tolerance with dendritic cell-targeting nanomedicines

Anna Cifuentes-Rius et al.

Summary: Induced tolerogenic dendritic cells offer a promising immunotherapy for autoimmune diseases, with nanomedicine presenting an alternative approach to overcome cost and customization limitations. By targeting dendritic cells with nanoparticles, this technology has the potential to address critical issues in organ transplantation and prevalent autoimmune disorders.

NATURE NANOTECHNOLOGY (2021)

Article Pharmacology & Pharmacy

Effect of Dexamethasone-Loaded PLGA Nanoparticles on Oral Mucositis Induced by 5-Fluorouracil

Susana Barbosa Ribeiro et al.

Summary: Oral mucositis, characterized by severe ulcers in the oral region from chemotherapy, lacks effective therapy. Dexamethasone-loaded nanoparticles showed therapeutic effects in a hamster model, reducing inflammation, oxidative stress, and modulating gene expression.

PHARMACEUTICS (2021)

Review Immunology

Dendritic Cell Regulation of T Helper Cells

Xiangyun Yin et al.

Summary: Dendritic cells play a crucial role in sensing the microenvironment and shaping the adaptive immune response. They consist of several subsets that regulate T lymphocyte differentiation and determine distinct CD4(+) T helper cell differentiation outcomes. The intrinsic properties of DC subsets, local tissue microenvironments, and interactions with other immune cells contribute to Th cell differentiation during homeostasis and inflammation.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 39 (2021)

Article Nanoscience & Nanotechnology

Induction of antigen-specific immune tolerance using biodegradable nanoparticles containing antigen and dexamethasone

Sang-Hyun Kim et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Review Immunology

The Complex Association of FcγRIIb With Autoimmune Susceptibility

J. Sjef Verbeek et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Immunology

Dendritic cell subsets in T cell programming: location dictates function

S. C. Eisenbarth

NATURE REVIEWS IMMUNOLOGY (2019)

Article Dermatology

Skin-Specific CD301b+ Dermal Dendritic Cells Drive IL-17-Mediated Psoriasis-Like Immune Response in Mice

Tae-Gyun Kim et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2018)

Article Immunology

Mechanisms of Tolerance induction by Dendritic Cells In Vivo

Hitoshi Hasegawa et al.

FRONTIERS IN IMMUNOLOGY (2018)

Review Biotechnology & Applied Microbiology

Regulatory T cells in the treatment of disease

Amir Sharabi et al.

NATURE REVIEWS DRUG DISCOVERY (2018)

Article Medicine, General & Internal

Systemic lupus erythematosus

Arvind Kaul et al.

NATURE REVIEWS DISEASE PRIMERS (2016)

Article Multidisciplinary Sciences

Functional Modulation of Regulatory T Cells by IL-2

Byung-In Moon et al.

PLOS ONE (2015)

Article Biophysics

PLGA-lipid liposphere as a promising platform for oral delivery of proteins

Tongtong Ma et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2014)

Review Biophysics

Biodegradable polymeric nanoparticles based drug delivery systems

Avnesh Kumari et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2010)

Article Multidisciplinary Sciences

A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus

Lisa C. Willcocks et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Chemistry, Multidisciplinary

Nonviral Vectors for Gene Delivery

Meredith A. Mintzer et al.

CHEMICAL REVIEWS (2009)

Article Materials Science, Multidisciplinary

Synthesis, characterization, and controllable drug release of pH-sensitive hybrid magnetic nanoparticles

Lilin Zhou et al.

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2009)

Article Immunology

Nanoparticles target distinct dendritic cell populations according to their size

Vania Manolova et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2008)

Article Polymer Science

PMMA colloid particles armored by clay layers with PDMAEMA polymer brushes

Jian Zhang et al.

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY (2008)

Article Pharmacology & Pharmacy

M-cell targeted biodegradable PLGA nanoparticles for oral immunization against hepatitis B

Prem N. Gupta et al.

JOURNAL OF DRUG TARGETING (2007)

Article Immunology

Dexamethasone induces IL-10-producing monocyte-derived dendritic cells with durable immaturity

CQ Xia et al.

SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2005)

Article Chemistry, Multidisciplinary

Colloidally stable amphibious nanocrystals derived from poly {[2-(dimethylamino)ethyl] methaerylate} capping

HW Duan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)