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JOURNAL OF RHEUMATOLOGY (2016)
A proof-of-concept study with the tyrosine kinase inhibitor nilotinib in spondyloarthritis
Jacqueline E. Paramarta et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2016)
ERAP1 reduces accumulation of aberrant and disulfide-linked forms of HLA-B27 on the cell surface
Tri M. Tran et al.
MOLECULAR IMMUNOLOGY (2016)
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity
Calliope A. Dendrou et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
IL-17-producing γδ T cells enhance bone regeneration
Takehito Ono et al.
NATURE COMMUNICATIONS (2016)
Sexual Dimorphism in the Th17 Signature of Ankylosing Spondylitis
Eric Gracey et al.
ARTHRITIS & RHEUMATOLOGY (2016)
Interleukin-23-Dependent/T Cells Produce Interleukin-17 and Accumulate in the Enthesis, Aortic Valve, and Ciliary Body in Mice
Annika Reinhardt et al.
ARTHRITIS & RHEUMATOLOGY (2016)
Type 3 innate lymphoid cells producing IL-17 and IL-22 are expanded in the gut, in the peripheral blood, synovial fluid and bone marrow of patients with ankylosing spondylitis
Francesco Ciccia et al.
ANNALS OF THE RHEUMATIC DISEASES (2015)
Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity
Patrick R. Burkett et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
The emerging role of resident memory T cells in protective immunity and inflammatory disease
Chang Ook Park et al.
NATURE MEDICINE (2015)
Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis
Dominique Baeten et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
Adrian Cortes et al.
NATURE COMMUNICATIONS (2015)
Axial spondyloarthritis
Joachim Sieper et al.
NATURE REVIEWS DISEASE PRIMERS (2015)
Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis
T. J. Kenna et al.
GENES AND IMMUNITY (2015)
The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains
Zhiyong Zhang et al.
PLOS ONE (2015)
Combined Inhibition of Tumor Necrosis Factor α and Interleukin-17 As a Therapeutic Opportunity in Rheumatoid Arthritis Development and Characterization of a Novel Bispecific Antibody
Jens A. A. Fischer et al.
ARTHRITIS & RHEUMATOLOGY (2015)
High prevalence of anti-CD74 antibodies specific for the HLA class II-associated invariant chain peptide (CLIP) in patients with axial spondyloarthritis
X. Baraliakos et al.
ANNALS OF THE RHEUMATIC DISEASES (2014)
Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation
Francesco Ciccia et al.
ANNALS OF THE RHEUMATIC DISEASES (2014)
Serum levels of novel noggin and sclerostin-immune complexes are elevated in ankylosing spondylitis
Florence W. L. Tsui et al.
ANNALS OF THE RHEUMATIC DISEASES (2014)
CX3CR1+ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22
Randy S. Longman et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
The IL-17A-Producing CD8+ T-Cell Population in Psoriatic Lesional Skin Comprises Mucosa-Associated Invariant T Cells and Conventional T Cells
Marcel B. M. Teunissen et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2014)
Functionally distinct ERAP1 allotype combinations distinguish individuals with Ankylosing Spondylitis
Emma Reeves et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Endoplasmic Reticulum Degradation-Enhancing α-Mannosidase-like Protein 1 Targets Misfolded HLA-B27 Dimers for Endoplasmic Reticulum-Associated Degradation
David B. Guiliano et al.
ARTHRITIS & RHEUMATOLOGY (2014)
Interleukin-23 Mediates the Intestinal Response to Microbial β-1,3-Glucan and the Development of Spondyloarthritis Pathology in SKG Mice
Helen Benham et al.
ARTHRITIS & RHEUMATOLOGY (2014)
Effects of interleukin-17A on osteogenic differentiation of isolated human mesenchymal stem cells
Bilal Osta et al.
FRONTIERS IN IMMUNOLOGY (2014)
Role of PI3K/Akt and mTOR complexes in Th17 cell differentiation
Shigenori Nagai et al.
INOSITOL PHOSPHOLIPID SIGNALING IN PHYSIOLOGY AND DISEASE (2013)
One-year follow-up of ankylosing spondylitis patients responding to rituximab treatment and re-treated in case of a flare
In-Ho Song et al.
ANNALS OF THE RHEUMATIC DISEASES (2013)
Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results of a randomised placebo-controlled trial (ABILITY-1)
Joachim Sieper et al.
ANNALS OF THE RHEUMATIC DISEASES (2013)
KIR3DL2 Binds to HLA-B27 Dimers and Free H Chains More Strongly than Other HLA Class I and Promotes the Expansion of T Cells in Ankylosing Spondylitis
Isabel Wong-Baeza et al.
JOURNAL OF IMMUNOLOGY (2013)
Neuronal IL-17 receptor upregulates TRPV4 but not TRPV1 receptors in DRG neurons and mediates mechanical but not thermal hyperalgesia
Gisela Segond von Banchet et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2013)
Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial
Iain B. McInnes et al.
LANCET (2013)
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
Adrian Cortes et al.
NATURE GENETICS (2013)
MECHANISMS OF DISEASE JAKs and STATs in Immunity, Immunodeficiency, and Cancer
John J. O'Shea et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Spinal interleukin-17 promotes thermal hyperalgesia and NMDA NR1 phosphorylation in an inflammatory pain rat model
Xianze Meng et al.
PAIN (2013)
Decreased Th17 and Th1 cells in the peripheral blood of patients with early non-radiographic axial spondyloarthritis: a marker of disease activity in HLA-B27+ patients
Maria-Belen Bautista-Caro et al.
RHEUMATOLOGY (2013)
The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09
Alberto Cauli et al.
RHEUMATOLOGY (2013)
Recognition of self and altered self by T cells in autoimmunity and allergy
Lei Yin et al.
PROTEIN & CELL (2013)
Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis
Nigil Haroon et al.
ANNALS OF THE RHEUMATIC DISEASES (2012)
Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis
Troy Noordenbos et al.
ARTHRITIS AND RHEUMATISM (2012)
Interleukin-17 Sensitizes Joint Nociceptors to Mechanical Stimuli and Contributes to Arthritic Pain Through Neuronal Interleukin-17 Receptors in Rodents
Frank Richter et al.
ARTHRITIS AND RHEUMATISM (2012)
Enrichment of Circulating Interleukin-17-Secreting Interleukin-23 Receptor-Positive γ/δ T Cells in Patients with Active Ankylosing Spondylitis
Tony J. Kenna et al.
ARTHRITIS AND RHEUMATISM (2012)
β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice
Merja Ruutu et al.
ARTHRITIS AND RHEUMATISM (2012)
IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells
Jonathan P. Sherlock et al.
NATURE MEDICINE (2012)
Epidemiology of Spondyloarthritis
Carmen Stolwijk et al.
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA (2012)
Functional differences between human NKp44(-) and NKp44(+) RORC+ innate lymphoid cells
Kerim Hoorweg et al.
FRONTIERS IN IMMUNOLOGY (2012)
Noggin
Carola Krause et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
Th17 Cells Expressing KIR3DL2+ and Responsive to HLA-B27 Homodimers Are Increased in Ankylosing Spondylitis
Paul Bowness et al.
JOURNAL OF IMMUNOLOGY (2011)
Analysis of IL-17(+) cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response
Heiner Appel et al.
ARTHRITIS RESEARCH & THERAPY (2011)
Invariant Natural Killer T Cells Are Natural Regulators of Murine Spondylarthritis
Peggy Jacques et al.
ARTHRITIS AND RHEUMATISM (2010)
Different Response to Rituximab in Tumor Necrosis Factor Blocker-Naive Patients With Active Ankylosing Spondylitis and in Patients in Whom Tumor Necrosis Factor Blockers Have Failed A Twenty-Four-Week Clinical Trial
I. -H. Song et al.
ARTHRITIS AND RHEUMATISM (2010)
Analysis of JAK2 and STAT3 polymorphisms in patients with ankylosing spondylitis in Chinese Han population
Chao Chen et al.
CLINICAL IMMUNOLOGY (2010)
IL-17 Contributes to Angiogenesis in Rheumatoid Arthritis
Sarah R. Pickens et al.
JOURNAL OF IMMUNOLOGY (2010)
The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes
Shinya Sakaguchi et al.
NATURE IMMUNOLOGY (2010)
IL-17 mediates articular hypernociception in antigen-induced arthritis in mice
Larissa G. Pinto et al.
PAIN (2010)
Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression
Jane C. Goodall et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Association of Variants at 1q32 and STAT3 with Ankylosing Spondylitis Suggests Genetic Overlap with Crohn's Disease
Patrick Danoy et al.
PLOS GENETICS (2010)
New criteria for inflammatory back pain in patients with chronic back pain: a real patient exercise by experts from the Assessment of SpondyloArthritis international Society (ASAS)
J. Sieper et al.
ANNALS OF THE RHEUMATIC DISEASES (2009)
Altered Skeletal Expression of Sclerostin and Its Link to Radiographic Progression in Ankylosing Spondylitis
Heiner Appel et al.
ARTHRITIS AND RHEUMATISM (2009)
Spondylarthritis in HLA-B27/Human β2-Microglobulin-Transgenic Rats Is Not Prevented by Lack of CD8
Joel D. Taurog et al.
ARTHRITIS AND RHEUMATISM (2009)
HLA-B27 Misfolding and the Unfolded Protein Response Augment Interleukin-23 Production and Are Associated With Th17 Activation in Transgenic Rats
Monica L. Delay et al.
ARTHRITIS AND RHEUMATISM (2009)
Efficacy and Safety of Golimumab in Patients With Ankylosing Spondylitis Results of a Randomized, Double-Blind, Placebo-Controlled, Phase III Trial
Robert D. Inman et al.
ARTHRITIS AND RHEUMATISM (2008)
Lack of short-term efficacy of rituximab upon symptoms of ankylosing spondylitis treated for an associated vasculitis
Daniel Wendling et al.
JOINT BONE SPINE (2008)
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
Melanie Newport et al.
NATURE GENETICS (2007)
The concept of a Synovio-Entheseal complex and its implications for understanding joint inflammation and damage in psoriatic arthritis and beyond
Dennis McGonagle et al.
ARTHRITIS AND RHEUMATISM (2007)
Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide
Simon Kollnberger et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
IL-17A acts via p38 MAPK to increase stability of TNF-β-induced IL-8 mRNA in human ASM
S Henness et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)
Expansion and enhanced survival of natural killer cells expressing the killer immunoglobulin-like receptor KIR3DL2 in spondylarthritis
AT Chan et al.
ARTHRITIS AND RHEUMATISM (2005)
HLA-B27 misfolding in transgenic rats is associated with activation of the unfolded protein response
MJ Turner et al.
JOURNAL OF IMMUNOLOGY (2005)
HLA-B27-Restricted CD8+T Cell Response to Cartilage-Derived Self Peptides in Ankylosing Spondylitis
Pamir Atagunduz et al.
ARTHRITIS AND RHEUMATISM (2005)
Efficacy and safety of infliximab in patients with ankylosing spondylitis - Results of a randomized, placebo-controlled trial (ASSERT)
D van der Heijde et al.
ARTHRITIS AND RHEUMATISM (2005)
Lymphoblastoid cells express HLA-1327 homodimers both intracellularly and at the cell surface following endosomal recycling
LA Bird et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Immunohistological study of entheses in spondyloarthropathies: comparison in rheumatoid arthritis and osteoarthritis
L Laloux et al.
ANNALS OF THE RHEUMATIC DISEASES (2001)
The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate
K Yasutomo et al.
NATURE (2000)
Quantitative analyses of sacroiliac biopsies in spondyloarthropathies: T cells and macro phages predominate in early and active sacroiliitis - cellularity correlates with the degree of enhancement detected by magnetic resonance imaging
M Bellow et al.
ANNALS OF THE RHEUMATIC DISEASES (2000)
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