☆ 4.7 Review

The Landscape of Circular RNAs in Cardiovascular Diseases

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Cell Biology

CircCAMTA1 facilitates atrial fibrosis by regulating the miR-214-3p/TGFBR1 axis in atrial fibrillation

Li Zhang et al.

Summary: This study found that circCAMTA1 can promote Ang-II-induced atrial fibrosis by downregulating miR-214-3p, and knockdown of circCAMTA1 can alleviate atrial fibrosis, suggesting that the circCAMTA1/miR-214-3p/TGFBR1 axis may be a novel therapeutic target for AF treatment.

JOURNAL OF MOLECULAR HISTOLOGY (2023)

添加到收藏夹

Article Cell Biology

A novel identified circular RNA, circSnap47, promotes heart failure progression via regulation of miR-223-3p/MAPK axis

Yunkai Wang et al.

Summary: The aim of this study was to investigate the effect of circSnap47 on heart failure and its potential mechanisms. The results showed that silencing circSnap47 increased cell viability, inhibited apoptosis, and alleviated inflammation. Furthermore, circSnap47 silencing relieved heart failure progression by regulating the miR-233/MAPK axis.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2023)

添加到收藏夹

Article Hematology

Propofol inhibits cell apoptosis and inflammatory response in ox-LDL-induced human umbilical vein endothelial cells through the modulation of the circ_0003645/miR-149-3p/TRAF7 axis

Min Chen et al.

Summary: This study investigated the functional mechanism of propofol and circ_0003645 in atherosclerosis (AS). The results showed that propofol protected against cell injury by downregulating circ_0003645 expression and reducing apoptosis and inflammation. circ_0003645 was involved in the regulation of propofol through the miR-149-3p/TRAF7 pathway.

CLINICAL HEMORHEOLOGY AND MICROCIRCULATION (2023)

添加到收藏夹

Article Medical Laboratory Technology

Hsa_circ_0000437 upregulates and promotes disease progression in rheumatic valvular heart disease

Linwen Zhu et al.

Summary: The study found that has_circ_0000437 is highly expressed in RVHD and has diagnostic value. In RVHD, hsa_circ_0000437 can promote cell proliferation and migration while inhibiting apoptosis. This may be due to the interaction of has_circ_0000437 with target miRNA in the cytoplasm affecting the progression of RVHD.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2022)

添加到收藏夹

Article Cell Biology

circRNA is a potential target for cardiovascular diseases treatment

Jie Ju et al.

Summary: circRNAs are a novel class of RNA with closed-loop structures, functioning as sponges for microRNAs and playing important regulatory roles in the development of cardiovascular diseases.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2022)

添加到收藏夹

Article Pediatrics

Bioinformatic analysis of dysregulated circular RNAs in pediatric pulmonary hypertension linked congenital heart disease

Danyan Su et al.

Summary: We identified differentially expressed circRNAs in plasma samples from children with CHD-associated pulmonary arterial hypertension. These circRNAs may be involved in the occurrence and regulation of pulmonary arterial hypertension, and are associated with oxidative phosphorylation and tight junction signaling.

TRANSLATIONAL PEDIATRICS (2022)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Study on the Mechanism of circRNA-0024103 Reducing Endothelial Cell Injury by Regulating miR-363/MMP-10

Yunfei Tian et al.

Summary: Exploring targeted therapeutic approaches for atherosclerosis is of great significance. circRNA-0024103 regulates the biological behaviors of endothelial cells, such as proliferation, apoptosis, migration, and invasion, through the miR-363/MMP-10 axis. This provides a new therapeutic target for the treatment of atherosclerosis.

CONTRAST MEDIA & MOLECULAR IMAGING (2022)

添加到收藏夹

Article Immunology

Circ_0050908 up-regulates TRAF3 by sponging miR-324-5p to aggravate myocardial ischemia-reperfusion injury

Aiping Jin et al.

Summary: This study found that knockdown of circ_0050908 can reduce apoptosis, inflammatory response, and oxidative stress in cardiomyocytes through the miR-324-5p/TRAF3 axis, protecting cardiomyocytes against I/R injury.

INTERNATIONAL IMMUNOPHARMACOLOGY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circ-CBFB exacerbates hypoxia/reoxygenation-triggered cardiomyocyte injury via regulating miR-495-3p in a VDAC1-dependent manner

Yue-e Chen et al.

Summary: This study demonstrates that absence of circ-CBFB offers cardio-protection against H/R-triggered cardiomyocyte injury by relieving apoptosis, oxidative stress, and mitochondria dysfunction through the miR-495-3p/VDAC1 axis.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2022)

添加到收藏夹

Correction Biochemistry & Molecular Biology

circ-CCND1 regulates the CCND1/P53/P21 pathway through sponging miR-138-5p in valve interstitial cells to aggravate aortic valve calcification (July, 10.1007/s13105-022-00907-3, 2022)

Fei Yan et al.

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2022)

添加到收藏夹

Article Cell Biology

CircANKRD12 Is Induced in Endothelial Cell Response to Oxidative Stress

Christine Voellenkle et al.

Summary: Redox imbalance of endothelial cells plays a crucial role in cardiovascular diseases. The study found that circular RNA circANKRD12 was significantly upregulated in endothelial cells exposed to oxidative stress, and its silencing inhibited endothelial cell proliferation and capillary-like structure formation. Furthermore, bioinformatics analysis revealed the enrichment of the p53 and Foxo signaling pathways in the circANKRD12-miRNA-mRNA regulatory network in H2O2-treated endothelial cells.

CELLS (2022)

添加到收藏夹

Review Genetics & Heredity

Circular RNAs: New Players in Cardiomyopathy

Maedeh Bagheri Moghaddam et al.

Summary: Cardiomyopathies are a group of cardiac diseases that lead to heart failure and mortality. Circular RNAs, a novel type of noncoding RNAs with unique structure, have been found to play significant roles in cardiomyopathies and have potential clinical applications.

GENES (2022)

添加到收藏夹

Article Cell Biology

Identifying Candidate Circulating RNA Markers for Coronary Artery Disease by Deep RNA-Sequencing in Human Plasma

Zoe Ward et al.

Summary: We developed a short-read RNA-Seq protocol to detect mRNAs, lncRNAs, and circRNAs in plasma for the discovery of novel markers for coronary artery disease (CAD) and heart failure (HF). We found that circulating levels of multiple coding and non-coding transcripts were altered in association with CAD, including several mitochondrial mRNAs. These findings suggest that circulating levels of these transcripts could potentially be used to identify asymptomatic individuals with established CAD before an acute coronary event.

CELLS (2022)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

CircHSPG2 absence weakens hypoxia-induced dysfunction in cardiomyocytes by targeting the miR-25-3p/PAWR axis

Ying Zhao et al.

Summary: The circRNA heparan sulfate proteoglycan 2 (circHSPG2) has been found to play a crucial regulatory role in hypoxia-induced myocardial infarction (MI). It acts as a sponge for miR-25-3p and positively regulates the expression of pro-apoptotic WT1 regulator (PAWR) by acting as a molecular sponge for miR-25-3p, thereby protecting AC-16 cells from hypoxia-induced dysfunction.

CARDIOVASCULAR DIAGNOSIS AND THERAPY (2022)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

mRNA, lncRNA, and circRNA expression profiles in a new aortic dissection murine model induced by hypoxia and Ang II

Yuanyuan Li et al.

Summary: The study found that there is a significant positive correlation between uric acid and glucose levels and carotid plaque volume, and a significant negative correlation with high-density lipoprotein cholesterol levels.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

添加到收藏夹

Article Critical Care Medicine

Circular RNAs to predict clinical outcome after cardiac arrest

Francesca M. Stefanizzi et al.

Summary: This study identified circulating circRNAs associated with clinical outcome after cardiac arrest, with circNFAT5 potentially aiding in predicting neurological outcome and survival in combination with established biomarkers of cardiac arrest.

INTENSIVE CARE MEDICINE EXPERIMENTAL (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Research paper Hsa_circ_0007478 aggravates NLRP3 inflammasome activation and lipid metabolism imbalance in ox-LDL-stimulated macrophage via miR-765/ EFNA3 axis

Bozhi Ye et al.

Summary: This study found that circular RNA hsa_circ_0007478 was upregulated in ox-LDL-stimulated macrophages, accompanied by reduced miR-765 and increased EFNA3 expression. Silencing of hsa_circ_0007478 or transfection of miR-765 mimics decreased the activation of NLRP3 inflammasome and IL-113 in macrophages. Hsa_circ_0007478 promoted EFNA3 expression by acting as a miR-765 sponge. These findings suggest that hsa_circ_0007478 may play an important role in the inflammatory response and foam cell formation in atherosclerosis.

CHEMICO-BIOLOGICAL INTERACTIONS (2022)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Circular RNA hsa_circ_0000848 Regulates Cardiomyocyte Proliferation and Apoptosis Under Hypoxia via Recruiting ELAVL1 and Stabilizing SMAD7 mRNA

Shuai Cao et al.

Summary: This study confirmed for the first time that the hsa_circ_0000848/ELAV-like RNA-binding protein 1/SMAD family member 7 axis could affect the development of cardiomyocyte cells cultured under hypoxic conditions, indicating that hsa_circ_0000848 might function as a novel biomarker in hypoxic cells, thus laying the groundwork for future study on myocardial infarction.

ANATOLIAN JOURNAL OF CARDIOLOGY (2022)

添加到收藏夹

Article Medical Laboratory Technology

Research on the circular RNA bioinformatics in patients with acute myocardial infarction

Lianli Yin et al.

Summary: Analysis of circRNAs in acute myocardial infarction (AMI) patients revealed 650 differentially expressed circRNAs, including those involved in multiple signaling pathways. These circRNAs are related to various diseases, such as myocardial infarction, coronary heart disease, and hypertension, and may play a role in the pathogenesis of AMI through interaction with microRNAs.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

The roles of non-coding RNAs in vascular calcification and opportunities as therapeutic targets

Juhee Ryu et al.

Summary: This article reviews the role and therapeutic implications of non-coding RNAs (ncRNAs) in vascular calcification (VC). Studies suggest that ncRNAs, including miRNAs, lncRNAs, and circRNAs, play important roles in regulating VC and may be useful in clinical diagnosis and treatment.

PHARMACOLOGY & THERAPEUTICS (2021)

添加到收藏夹

Article Hematology

CircSOD2: A Novel Regulator for Smooth Muscle Proliferation and Neointima Formation

Xiaohan Mei et al.

Summary: The study discovered that circular RNA circSOD2 plays a crucial role in neointima formation following vascular injury by regulating vascular smooth muscle cell (SMC) proliferation through the miR-206/NOTCH3 pathway. circSOD2 serves as a potential therapeutic target for inhibiting the development of proliferative vascular diseases.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Circular RNA CircMAP3K5 Acts as a MicroRNA-22-3p Sponge to Promote Resolution of Intimal Hyperplasia Via TET2-Mediated Smooth Muscle Cell Differentiation

Zhi Zeng et al.

Summary: The study demonstrates that circMAP3K5 acts as a regulator of neointimal hyperplasia by sequestering miR-22-3p to inhibit TET2 expression, and subsequently affecting vascular smooth muscle cell differentiation and proliferation. Targeting the circMAP3K5/miR-22-3p/TET2 axis may offer a potential therapeutic strategy for diseases associated with intimal hyperplasia, including restenosis and atherosclerosis.

CIRCULATION (2021)

添加到收藏夹

Review Medicine, Research & Experimental

CircRNAs open a new era in the study of cardiovascular disease (Review)

Zhikang Yu et al.

Summary: Circular RNAs (circRNAs) are non-coding RNAs widely expressed in mammalian tissues and cells, associated with the physiology and pathology of cardiovascular diseases (CVDs) as effector molecules and biomarkers in the cardiovascular system.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2021)

添加到收藏夹

Article Cell Biology

Analysis of changes in circular RNA expression and construction of ceRNA networks in human dilated cardiomyopathy

Zhenhao Lin et al.

Summary: This study revealed altered expression of cardiac circRNAs in human DCM and explored their potential functions by constructing ceRNA networks. These findings provide a foundation for future studies of circRNAs in DCM.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

添加到收藏夹

Review Cell Biology

Circular RNA in cardiovascular disease: Expression, mechanisms and clinical prospects

Ying Tang et al.

Summary: Circular RNAs (circRNAs) are a group of endogenous non-coding RNAs that widely exist in human tissues, including the heart, and play crucial regulatory roles in cardiovascular diseases (CVDs). They are conserved, stable and have specific spatiotemporal expression, making them potential diagnostic markers or prognostic biomarkers for CVDs.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

添加到收藏夹

Article Medical Laboratory Technology

The microarray identification circular RNA hsa_circ_0105015 up-regulated involving inflammation pathway in essential hypertension

Xin He et al.

Summary: This study identified that the high expression of circRNA hsa_circ_0105015 is associated with inflammatory pathways in Essential hypertension (EH) patients, and the combination with low expression of hsa-miR-637 may indicate vascular inflammation or endothelial dysfunction, serving as a potential biomarker for early diagnosis of EH.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2021)

添加到收藏夹

Article Biochemical Research Methods

Screening for functional circular RNAs using the CRISPR-Cas13 system

Siqi Li et al.

Summary: The study demonstrates that CRISPR-RfxCas13d can effectively discriminate circRNAs from mRNAs and has identified important circRNAs involved in cell growth, such as the pro-proliferative circFAM120A and the regulatory circMan1a2 in mouse embryo preimplantation development.

NATURE METHODS (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Circular RNA PVT1 silencing prevents ischemia-reperfusion injury in rat by targeting microRNA-125b and microRNA-200a

Cheng Luo et al.

Summary: This study found that circPVT1 has a protective role in myocardial infarction and H/R conditions, reducing cardiomyocyte apoptosis and restoring cell proliferation and viability.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

CircSLC8A1 and circNFIX can be used as auxiliary diagnostic markers for sudden cardiac death caused by acute ischemic heart disease

Meihui Tian et al.

Summary: The study found that circNFIX and circSLC8A1, two heart-enriched circRNAs, may have potential as biomarkers for sudden cardiac death caused by acute ischemic heart disease, with good diagnostic performance.

SCIENTIFIC REPORTS (2021)

添加到收藏夹

Article Genetics & Heredity

Identification of Regulatory circRNAs Involved in the Pathogenesis of Acute Myocardial Infarction

Cuimei Zhao et al.

Summary: Through analyzing the blood samples of AMI patients and normal controls, 142 differentially expressed circRNAs were identified. Functional characterization revealed that circRNAs were mainly involved in seven pathways, such as the Runt-related transcription factor-1 (RUNX1) expression and activity-related pathway.

FRONTIERS IN GENETICS (2021)

添加到收藏夹

Article Medicine, Research & Experimental

circGNAQ, a circular RNA enriched in vascular endothelium, inhibits endothelial cell senescence and atherosclerosis progression

Wei-peng Wu et al.

Summary: The study suggests that circGNAQ plays critical roles in endothelial cell senescence and atherosclerosis by acting as a sponge for miR-146a-5p, delaying the aging process in endothelial cells.

MOLECULAR THERAPY-NUCLEIC ACIDS (2021)

添加到收藏夹

Article Cell Biology

CircRNA circ-NNT mediates myocardial ischemia/reperfusion injury through activating pyroptosis by sponging miR-33a-5p and regulating USP46 expression

Xiaomiao Ye et al.

Summary: This study demonstrates the activation of pyroptosis during myocardial ischemia/reperfusion injury and its role in reperfusion injury. Circ-NNT promotes pyroptosis and myocardial I/R injury by acting as a miR-33a-5p sponge to regulate USP46. The circ-NNT -> miR-33a-5p -> USP46 signaling axis may be a potential target for developing cardio-protective agents to improve the clinical outcome of reperfusion therapy.

CELL DEATH DISCOVERY (2021)

添加到收藏夹

Article Genetics & Heredity

Detection of circRNA Biomarker for Acute Myocardial Infarction Based on System Biological Analysis of RNA Expression

Wen Yang et al.

Summary: The study identified new circRNA biomarkers for AMI through biological analyses and validated their effectiveness and efficiency in the diagnosis and therapy of AMI.

FRONTIERS IN GENETICS (2021)

添加到收藏夹

Article Cell Biology

Overexpression of circRNA SNRK targets miR-103-3p to reduce apoptosis and promote cardiac repair through GSK3β/β-catenin pathway in rats with myocardial infarction

Yeqian Zhu et al.

Summary: The upregulation of circSNRK in the heart promotes cardiac survival and functional recovery after myocardial infarction by acting as a miR-103-3p sponge and inducing increased expression of SNRK to regulate cardiomyocyte apoptosis and proliferation. This suggests that circSNRK may be a promising therapeutic target for improving clinical prognosis after myocardial infarction.

CELL DEATH DISCOVERY (2021)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Circular RNAs and Cardiovascular Regeneration

Ling Tang et al.

Summary: circRNAs are a type of stable, abundantly expressed non-coding RNA with cell or tissue specificity, which play important roles in the pathogenesis of cardiovascular diseases. Research on the differential expression of circRNAs in heart tissues and their modes of action may lead to their use as ideal diagnostic biomarkers and effective therapeutic targets.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Construction and investigation of a circRNA-associated ceRNA regulatory network in Tetralogy of Fallot

Haifei Yu et al.

Summary: A total of 276 differentially expressed circRNAs were identified in TOF samples, with 214 upregulated and 62 downregulated circRNAs. By constructing a circRNA-associated ceRNA network based on bioinformatics data, 19 circRNAs, 9 miRNAs, and 34 mRNAs were further screened. Additionally, qPCR results validated a positive correlation between hsa_circ_0007798 and HIF1A, suggesting a potential role in TOF pathogenesis.

BMC CARDIOVASCULAR DISORDERS (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Decoding the complexity of circular RNAs in cardiovascular disease

Amit Kumar Rai et al.

Summary: Circular RNAs (circRNAs) are a newly discovered class of noncoding RNAs found widely in the human heart, with emerging evidence suggesting they play regulatory roles in various cardiovascular diseases. Current understanding of circRNA focuses on their classification, biogenesis, function, stability, degradation mechanisms, and their potential as promising targets for understanding and treating CVD.

PHARMACOLOGICAL RESEARCH (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation

Xue Gong et al.

Summary: This study identified a potentially novel circRNA, circEsyt2, that regulates vascular remodeling by interacting with the protein PCBP1 to control RNA splicing, affecting proliferation and migration of vascular smooth muscle cells and neointima formation in atherosclerotic mouse models.

JOURNAL OF CLINICAL INVESTIGATION (2021)

添加到收藏夹

Review Biochemical Research Methods

Closing the circle: current state and perspectives of circular RNA databases

Marieke Vromman et al.

Summary: Major issues with current circRNA databases include limited content overlap, ambiguous nomenclature, inability to uniquely identify circRNA molecules, and annotations based on presumed circRNA sequences.

BRIEFINGS IN BIOINFORMATICS (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Circular RNA circRNA_000203 aggravates cardiac hypertrophy via suppressing miR-26b-5p and miR-140-3p binding to Gata4

Hui Li et al.

CARDIOVASCULAR RESEARCH (2020)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Circular RNA expression profile and its potential regulative role in human abdominal aortic aneurysm

Min Zhou et al.

BMC CARDIOVASCULAR DISORDERS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Plasma circular RNA hsa_circ_0001445 and coronary artery disease: Performance as a biomarker

David Vilades et al.

FASEB JOURNAL (2020)

添加到收藏夹

Article Genetics & Heredity

Genome-wide profiling reveals atrial fibrillation-related circular RNAs in atrial appendages

Peng-Pai Zhang et al.

GENE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circular RNA Expression Profiles in Plasma from Patients with Heart Failure Related to Platelet Activity

Yeying Sun et al.

BIOMOLECULES (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circ_BMP2K enhances the regulatory effects of miR-455-3p on its target gene SUMO1 and thereby inhibits the activation of cardiac fibroblasts

Lei Zhang et al.

BIOCHEMISTRY AND CELL BIOLOGY (2020)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Role of Circular RNAs in Cardiovascular Disease

Raj Kishore et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2020)

添加到收藏夹

Article Oncology

Comprehensive molecular characterization of circRNA-associated ceRNA network in constrictive pericarditis

Yixin Chen et al.

ANNALS OF TRANSLATIONAL MEDICINE (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

CircANXA2 Promotes Myocardial Apoptosis in Myocardial Ischemia-Reperfusion Injury via Inhibiting miRNA-133 Expression

Liang Zong et al.

BIOMED RESEARCH INTERNATIONAL (2020)

添加到收藏夹

Article Genetics & Heredity

Comprehensive Construction of a Circular RNA-Associated Competing Endogenous RNA Network Identified Novel Circular RNAs in Hypertrophic Cardiomyopathy by Integrated Analysis

Qi Guo et al.

FRONTIERS IN GENETICS (2020)

添加到收藏夹

Article Medicine, Research & Experimental

Circular RNAs in the pathogenesis of atherosclerosis

Qidong Cao et al.

LIFE SCIENCES (2020)

添加到收藏夹

Article Medical Laboratory Technology

Association between circular RNA expression content and severity of coronary atherosclerosis in human coronary artery

Can Hou et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2020)

添加到收藏夹

Article Medicine, Research & Experimental

circPAN3 exerts a profibrotic role via sponging miR-221 through FoxO3/ATG7-activated autophagy in a rat model of myocardial infarction

Fei Li et al.

LIFE SCIENCES (2020)

添加到收藏夹

Article Medicine, Research & Experimental

circRNA Hipk3 Induces Cardiac Regeneration after Myocardial Infarction in Mice by Binding to Notch1 and miR-133a

Xiaoyun Si et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2020)

添加到收藏夹

Review Medicine, Research & Experimental

Rapid Development of Targeting circRNAs in Cardiovascular Diseases

Chao Zhang et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2020)

添加到收藏夹

Review Cell Biology

Circular RNAs: Functions and Clinical Significance in Cardiovascular Disease

Lei Zhang et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

添加到收藏夹

Correction Biotechnology & Applied Microbiology

Expression Profiles and Ontology Analysis of Circular RNAs in a Mouse Model of Myocardial Ischemia/Reperfusion Injury (vol 2020, 2346369, 2020)

Zhaoqing Sun et al.

BIOMED RESEARCH INTERNATIONAL (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

MicroRNA-221-3p promotes pulmonary artery smooth muscle cells proliferation by targeting AXIN2 during pulmonary arterial hypertension

Xiaowei Nie et al.

VASCULAR PHARMACOLOGY (2019)

添加到收藏夹

Article Medical Laboratory Technology

Up-regulation of circular RNA hsa_circ_0037909 promotes essential hypertension

Xingjie Bao et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2019)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Targeting the highly abundant circular RNA circSlc8a1 in cardiomyocytes attenuates pressure overload induced hypertrophy

Tingsen Benson Lim et al.

CARDIOVASCULAR RESEARCH (2019)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Circular RNAs open a new chapter in cardiovascular biology

Simona Aufiero et al.

NATURE REVIEWS CARDIOLOGY (2019)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Identification of circular RNA Hsa_circ_0001879 and Hsa_circ_0004104 as novel biomarkers for coronary artery disease

Laiyuan Wang et al.

ATHEROSCLEROSIS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circ_RUSC2 upregulates the expression of miR-661 target gene SYK and regulates the function of vascular smooth muscle cells

Jingang Sun et al.

BIOCHEMISTRY AND CELL BIOLOGY (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

How are circRNAs translated by non-canonical initiation mechanisms?

Leila Halidou Diallo et al.

BIOCHIMIE (2019)

添加到收藏夹

Article Genetics & Heredity

The Integrative Regulatory Network of circRNA, microRNA, and mRNA in Atrial Fibrillation

Shengyang Jiang et al.

FRONTIERS IN GENETICS (2019)

添加到收藏夹

Article Genetics & Heredity

Upregulation of Circular RNA CircNFIB Attenuates Cardiac Fibrosis by Sponging miR-433

Yujiao Zhu et al.

FRONTIERS IN GENETICS (2019)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Association of circular RNAs and environmental risk factors with coronary heart disease

Yi Sun et al.

BMC CARDIOVASCULAR DISORDERS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

circDLPAG4/HECTD1 mediates ischaemia/reperfusion injury in endothelial cells via ER stress

Lulu Chen et al.

RNA Biology (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis

Venkata Naga Srikanth Garikipati et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Review Cell Biology

Circular RNA in cardiovascular disease

M-Ashraf Altesha et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Circular RNA expression alterations in extracellular vesicles isolated from murine heart post ischemia/reperfusion injury

Xinyu Ge et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2019)

添加到收藏夹

Article Medicine, Research & Experimental

Circular RNAs negatively regulate cancer stem cells by physically binding FMRP against CCAR1 complex in hepatocellular carcinoma

Yan-Jing Zhu et al.

THERANOSTICS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

A potential risk factor of essential hypertension in case-control study: Circular RNA hsa_circ_0037911

Xingjie Bao et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling

Maarten M. G. van den Hoogenhof et al.

CIRCULATION (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis

Maolei Zhang et al.

ONCOGENE (2018)

添加到收藏夹

Article Multidisciplinary Sciences

Engineering circular RNA for potent and stable translation in eukaryotic cells

R. Alexander Wesselhoeft et al.

NATURE COMMUNICATIONS (2018)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Plasma Circular RNAs, Hsa_circRNA_025016, Predict Postoperative Atrial Fibrillation After Isolated Off-Pump Coronary Artery Bypass Grafting

Jian Zhang et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)

添加到收藏夹

Article Cell Biology

Comprehensive analysis of circRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of atnerosclerosis in rabbits

Feng Zhang et al.

AGING-US (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circ-SATB2 upregulates STIM1 expression and regulates vascular smooth muscle cell proliferation and differentiation through miR-939

Yan-yang Mao et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

添加到收藏夹

Review Biochemistry & Molecular Biology

The Biogenesis, Functions, and Challenges of Circular RNAs

Xiang Li et al.

MOLECULAR CELL (2018)

添加到收藏夹

Article Genetics & Heredity

CIRCpedia v2: An Updated Database for Comprehensive Circular RNA Annotation and Expression Comparison

Rui Dong et al.

GENOMICS PROTEOMICS & BIOINFORMATICS (2018)

添加到收藏夹

Review Biochemistry & Molecular Biology

Molecular roles and function of circular RNAs in eukaryotic cells

Lesca M. Holdt et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1

Amaresh C. Panda et al.

NUCLEIC ACIDS RESEARCH (2017)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Circular RNAs in heart failure

Yvan Devaux et al.

EUROPEAN JOURNAL OF HEART FAILURE (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

Ivano Legnini et al.

MOLECULAR CELL (2017)

添加到收藏夹

Article Oncology

Circular RNA expression profile and potential function of hsa_circRNA_101238 in human thoracic aortic dissection

Meisheng Zou et al.

ONCOTARGET (2017)

添加到收藏夹

Article Oncology

Circular RNAs promote TRPM3 expression by inhibiting hsa-miR-130a-3p in coronary artery disease patients

Ren-You Pan et al.

ONCOTARGET (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Peripheral blood circular RNA hsa_circ_0124644 can be used as a diagnostic biomarker of coronary artery disease

Zhenzhou Zhao et al.

SCIENTIFIC REPORTS (2017)

添加到收藏夹

Article Cell Biology

Effect of Circular ANRIL on the Inflammatory Response of Vascular Endothelial Cells in a Rat Model of Coronary Atherosclerosis

Chun-Li Song et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

添加到收藏夹

Review Cell Biology

Nutrition and other lifestyle influences on arterial aging

Thomas J. LaRocca et al.

AGEING RESEARCH REVIEWS (2017)

添加到收藏夹

Article Medicine, Research & Experimental

Circular RNA hsa_circ_0003575 regulates oxLDL induced vascular endothelial cells proliferation and angiogenesis

Chen-Ye Li et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circular RNA hsa_circ_0010729 regulates vascular endothelial cell proliferation and apoptosis by targeting the miR-186/HIF-1α axis

Rui-Ying Dang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)

添加到收藏夹

Article Pharmacology & Pharmacy

Profiling and bioinformatics analyses reveal differential circular RNA expression in hypertensive patients

Na Wu et al.

CLINICAL AND EXPERIMENTAL HYPERTENSION (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

A novel identified circular RNA, circRNA_010567, promotes myocardial fibrosis via suppressing miR-141 by targeting TGF-β1

Bing Zhou et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circular RNA mediates cardiomyocyte death via miRNA-dependent upregulation of MTP18 expression

Kun Wang et al.

CELL DEATH AND DIFFERENTIATION (2017)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

RBM20 Regulates Circular RNA Production From the Titin Gene

Mohsin A. F. Khan et al.

CIRCULATION RESEARCH (2016)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223

Kun Wang et al.

EUROPEAN HEART JOURNAL (2016)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Inflammatory cytokines in atherosclerosis: current therapeutic approaches

Dimitris Tousoulis et al.

EUROPEAN HEART JOURNAL (2016)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Characterization of circular RNAs in human, mouse and rat hearts

Stanislas Werfel et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)

添加到收藏夹

Letter Cardiac & Cardiovascular Systems

Myocardial Infarction-Associated Circular RNA Predicting Left Ventricular Dysfunction

Melanie Vausort et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

William W. Du et al.

NUCLEIC ACIDS RESEARCH (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans

Lesca M. Holdt et al.

NATURE COMMUNICATIONS (2016)

添加到收藏夹

Article Multidisciplinary Sciences

The Circular RNA Cdr1as Promotes Myocardial Infarction by Mediating the Regulation of miR-7a on Its Target Genes Expression

Hai-Hua Geng et al.

PLOS ONE (2016)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Identification and Characterization of Hypoxia-Regulated Endothelial Circular RNA

Jes-Niels Boeckel et al.

CIRCULATION RESEARCH (2015)

添加到收藏夹

Article Medical Laboratory Technology

Using circular RNA as a novel type of biomarker in the screening of gastric cancer

Peifei Li et al.

CLINICA CHIMICA ACTA (2015)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Which heart failure patients profit from natriuretic peptide guided therapy? A meta-analysis from individual patient data of randomized trials

Hans-Peter Brunner-La Rocca et al.

EUROPEAN JOURNAL OF HEART FAILURE (2015)

添加到收藏夹

Article Oncology

Cyclic RNA hsa-circ-000595 regulates apoptosis of aortic smooth muscle cells

Chengfei Zheng et al.

MOLECULAR MEDICINE REPORTS (2015)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Effect of B-type natriuretic peptide-guided treatment of chronic heart failure on total mortality and hospitalization: an individual patient meta-analysis

Richard W. Troughton et al.

EUROPEAN HEART JOURNAL (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

circRNA Biogenesis Competes with Pre-mRNA Splicing

Reut Ashwal-Fluss et al.

MOLECULAR CELL (2014)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Detecting and characterizing circular RNAs

William R. Jeck et al.

NATURE BIOTECHNOLOGY (2014)

添加到收藏夹

Article Multidisciplinary Sciences

Noninvasive in vivo monitoring of tissue-specific global gene expression in humans

Winston Koh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circular Intronic Long Noncoding RNAs

Yang Zhang et al.

MOLECULAR CELL (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Circular RNAs are a large class of animal RNAs with regulatory potency

Sebastian Memczak et al.

NATURE (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circular RNAs are abundant, conserved, and associated with ALU repeats

William R. Jeck et al.

RNA (2013)

添加到收藏夹

Article Genetics & Heredity

Correction: Cell-Type Specific Features of Circular RNA Expression

Julia Salzman et al.

PLoS Genetics (2013)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Pregnenolone Sulphate- and Cholesterol-Regulated TRPM3 Channels Coupled to Vascular Smooth Muscle Secretion and Contraction

Jacqueline Naylor et al.

CIRCULATION RESEARCH (2010)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

MIR-155 AND MIR-221/222 ATTENUATE ANGIOTENSION II INDUCED ENDOTHELIAL INFLAMMATION BY TARGETING ETS-1

Ni Zhu et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

添加到收藏夹

Article Genetics & Heredity

Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk

Christin E. Burd et al.

PLOS GENETICS (2010)

添加到收藏夹

Article Cell Biology

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

Xi Chen et al.

CELL RESEARCH (2008)

添加到收藏夹

Review Multidisciplinary Sciences

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Paul R. Burton et al.

NATURE (2007)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.