☆ 4.7 Review

Mesoporous Silica Nanoparticles as a Potential Nanoplatform: Therapeutic Applications and Considerations

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Nanoscience & Nanotechnology

Combined Anti-Angiogenic and Anti-Inflammatory Nanoformulation for Effective Treatment of Ocular Vascular Diseases

Jianguo Sun et al.

Summary: In this study, a dual-drug nanocomposite formulation was developed for the treatment of ocular vascular diseases. The formulation, CBC-MCC@hMSN(SM) complex, effectively suppressed angiogenesis and inflammatory responses both in vitro and in vivo. A single intraocular injection of this complex showed sustained efficacy for up to 6 months in treating diabetes-induced retinal vascular dysfunction and choroidal neovascularization.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2023)

添加到收藏夹

Review Pharmacology & Pharmacy

Nanomedicine-based commercial formulations: current developments and future prospects

Raj Kumar Thapa et al.

Summary: In recent decades, there has been a significant increase in the number of nanomedicine-based formulations, which offer controlled/targeted drug delivery, increased efficacy, and reduced toxicity, making them ideal for treating complex diseases like cancer. This review focuses on the development of nanomedicine-based formulations, approved nanomedicines, challenges in development, and future prospects.

JOURNAL OF PHARMACEUTICAL INVESTIGATION (2023)

添加到收藏夹

Article Chemistry, Multidisciplinary

Chitosan/alginate bionanocomposites adorned with mesoporous silica nanoparticles for bone tissue engineering

Satar Yousefiasl et al.

Summary: The regeneration of oral and craniofacial bone defects imposes a global health burden, and conventional therapies have limitations, highlighting the need for unique treatment strategies like tissue engineering. Mesoporous silica nanoparticles (MSNs) were found to enhance the mechanical strength of scaffolds without decreasing porosity. The MSN-containing scaffolds exhibited desirable swelling behaviors, low hydrolytic degradation, and no cytotoxicity. Therefore, Alg/Chit/MSN30 scaffolds are considered promising for bone tissue regeneration.

JOURNAL OF NANOSTRUCTURE IN CHEMISTRY (2023)

添加到收藏夹

Review Pharmacology & Pharmacy

Multifunctional lipidic nanocarriers for effective therapy of glioblastoma: recent advances in stimuli-responsive, receptor and subcellular targeted approaches

Manasa Manjunath Hegde et al.

Summary: In-depth research on lipid-based nanoparticles for GBM drug delivery is essential for advancing neuro-oncology research and improving outcomes in brain tumor patients. These nanoparticles show potential for both passive and active drug targeting, crossing or bypassing the BBB while minimizing toxicity and enhancing pharmacological parameters. However, further studies are needed to fully understand and utilize these nanocarriers for the treatment of GBM.

JOURNAL OF PHARMACEUTICAL INVESTIGATION (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Effects of lipid nanoparticles on physicochemical properties, cellular uptake, and lymphatic uptake of 6-methoxflavone

Suji Ryu et al.

Summary: This study aimed to investigate the effect of solid lipid nanoparticles (SLN) and nanostructured lipid carrier (NLC) on the lymphatic uptake of 6-methoxyflavone (6MF). The results showed that SLN and NLC could improve the oral bioavailability and sustained therapeutic effect of 6MF. The composition of lipid matrix affected the physicochemical properties and release profiles of 6MF. Encapsulation of 6MF in lipid nanoparticles enhanced its cellular uptake. In vivo lymphatic uptake studies in rats revealed that SLN and NLC significantly improved the lymphatic uptake of 6MF.

JOURNAL OF PHARMACEUTICAL INVESTIGATION (2022)

添加到收藏夹

Article Neurosciences

Polysorbate-coated mesoporous silica nanoparticles as an efficient carrier for improved rivastigmine brain delivery

Samaneh Fateh Basharzad et al.

Summary: This study developed a highly biocompatible nanosystem to deliver drugs to the brain, overcoming the blood-brain barrier and improving drug efficiency.

BRAIN RESEARCH (2022)

添加到收藏夹

Article Chemistry, Physical

Nitric oxide-driven nanomotors with bowl-shaped mesoporous silica for targeted thrombolysis

Yingfang Tao et al.

Summary: In this study, bowl-shaped silica nanomotors were designed to target the thrombus surface by modifying arginine-glycine-aspartic acid (RGD) polypeptide, and simultaneously loading l-arginine (LA) and thrombolytic drug urokinase (UK). These nanomotors can improve the drug utilization rate at the thrombus site by generating nitric oxide (NO), while eliminating reactive oxygen species and reducing oxidative stress in inflammatory endothelial cells.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Current approaches of nanomedicines in the market and various stage of clinical translation

Xiaoting Shan et al.

Summary: Compared with traditional drug therapy, nanomedicines have shown intriguing biological features that enhance therapeutic efficiency and reduce toxicity. This review provides an overview of currently launched or in-clinical-trial nanomedicines, highlighting the diversified trends in carrier types, applied indications, and mechanisms of action. Additionally, the review presents the applications of nanomedicines in the prevention, diagnosis, and treatment of various diseases, such as cancer, infections, blood disorders, cardiovascular diseases, immuno-associated diseases, and nervous system diseases. The article also offers considerations and perspectives for the research and development of nanomedicines to facilitate their translation into clinical practice.

ACTA PHARMACEUTICA SINICA B (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Dexamethasone-Loaded Radially Mesoporous Silica Nanoparticles for Sustained Anti-Inflammatory Effects in Rheumatoid Arthritis

Sang Jun Kim et al.

Summary: This study proposes radially mesoporous silica nanoparticles as a carrier for dexamethasone, achieving sustained anti-inflammatory effects in rheumatoid arthritis. The nanoparticles demonstrate high-capacity loading and sustained release of the drug, resulting in improved delivery efficiency compared to traditional silica nanoparticles. In vivo evaluation confirms the sustained anti-inflammatory effects and cartilage recovery in a rat model of the disease.

PHARMACEUTICS (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Combining Mg-Zn-Ca Bulk Metallic Glass with a Mesoporous Silica Nanocomposite for Bone Tissue Engineering

Yun Shin Chu et al.

Summary: Mg-Zn-Ca bulk metallic glass (BMG) is a promising orthopedic fixation implant due to its biodegradability and biocompatibility. In this study, Osteogenic growth peptide (OGP) containing mesoporous silica nanoparticles (MSNs) were combined with BMG materials to promote bone regeneration.

PHARMACEUTICS (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Stimuli-responsive nanoassemblies for targeted delivery against tumor and its microenvironment

Chin Siew Sia et al.

Summary: This review discusses the application and design requirements of nanoassemblies in tumor-targeted diagnosis and therapy, describing the characteristics of the tumor microenvironment and multiple barriers that need to be overcome for successful drug delivery.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2022)

添加到收藏夹

Review Chemistry, Physical

Recent trends in mesoporous silica nanoparticles of rode-like morphology for cancer theranostics: A review

Saman Sargazi et al.

Summary: The shape of nanoparticles is crucial for drug delivery efficiency. Rod-shaped mesoporous silica nanoparticles (RMSNs) have shown advantages over spherical MSNs in targeted drug delivery. RMSNs have desirable properties such as biocompatibility, low toxicity, large surface area, and stability, making them a perfect nanostructure. They have been utilized in various applications including bioimaging, cancer treatment, and drug/gene delivery.

JOURNAL OF MOLECULAR STRUCTURE (2022)

添加到收藏夹

Article Chemistry, Analytical

Detection of viruses by probe-gated silica nanoparticles directly from swab samples

Bilge Guvenc Tuna et al.

Summary: This study presents a direct and fast detection method for the CoV-2 genome in nose-throat swab samples, without the need for further processing. The method utilizes fluorescein-loaded mesoporous silica nanoparticles with specific gene sequence probes on their surface, which are released upon hybridization with the target viral genome.

TALANTA (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Influence of Critical Parameters on Cytotoxicity Induced by Mesoporous Silica Nanoparticles

Amirsadra Ahmadi et al.

Summary: This study statistically analyzed the factors influencing the biocompatibility and toxicity of Mesoporous Silica Nanoparticles (MSNs) in the past five years, including physicochemical properties, experimental conditions, and other experimental parameters.

NANOMATERIALS (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction

Han Li et al.

Summary: This study developed a targeted drug delivery system to deliver Notoginsenoside R1 (NGR1) to the infarcted myocardium, improving cardiac function and angiogenesis. The mechanism of NGR1 in myocardial protection was found to involve the AKT, MAPK, and Hippo signaling pathways.

REDOX BIOLOGY (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Hyaluronic Acid-Functionalized Mesoporous Silica Nanoparticles Loading Simvastatin for Targeted Therapy of Atherosclerosis

Kechen Song et al.

Summary: In this study, an enzyme-responsive and macrophage-targeting drug delivery system was constructed for precise treatment of atherosclerosis. The results showed that the system had high drug loading efficiency and enzyme-responsive release, as well as robust targeting, anti-inflammatory, and anti-foaming effects, with low cytotoxicity and excellent hemocompatibility.

PHARMACEUTICS (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Progress and recent trends in photodynamic therapy with nanoparticles

Kiyon Rhew et al.

Summary: This review discusses the progress and trends in nanoplatform-based photodynamic therapy (PDT) for various cancers and infectious diseases. The combination of nanotechnology and PDT has shown improved therapeutic efficacy and reduced side effects. However, more safety data are needed for these innovative strategies to advance into clinical trials.

JOURNAL OF PHARMACEUTICAL INVESTIGATION (2022)

添加到收藏夹

Article Chemistry, Analytical

Variations in in vitro toxicity of silica nanoparticles according to scaffold type in a 3D culture system using a micropillar/microwell chip platform

In Young Kim et al.

Summary: In this study, the cytotoxicity of SiO2 nanoparticles was compared in different cell culture systems and scaffold materials. The results showed that the cytotoxicity of SiO2 nanoparticles can be influenced by both the culture system and scaffold type.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

添加到收藏夹

Article Chemistry, Analytical

Simultaneous detection of two ovarian cancer biomarkers in human serums with biotin-enriched dendritic mesoporous silica nanoparticles-labeled multiplex lateral flow immunoassay

Hao Liu et al.

Summary: In this study, a novel BDMSNs-MLFIA method was developed for simultaneous detection of ovarian cancer biomarkers CA125 and HE4, showing high accuracy and sensitivity. This method is of great significance for improving the accuracy of ovarian cancer diagnosis and the survival rate of patients.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Curcumin-Loaded Mesoporous Silica Nanoparticles Dispersed in Thermo-Responsive Hydrogel as Potential Alzheimer Disease Therapy

Tais de Cassia Ribeiro et al.

Summary: This study investigated the use of curcumin-loaded mesoporous silica nanoparticles (MSN-CCM) and a thermo-responsive hydrogel for the treatment of Alzheimer's disease (AD). The results showed that the MSN-CCM and hydrogel had excellent properties and high permeation values. In vivo studies confirmed the potential of the hydrogel-MSN-CCM formulation in reverting cognitive deficits in an AD model.

PHARMACEUTICS (2022)

添加到收藏夹

Article Chemistry, Physical

Non-ionic surfactants As co-templates to control the mesopore diameter of hollow mesoporous silica nanoparticles for drug delivery applications

Ngoc Hoi Nguyen et al.

Summary: This study aims to use non-ionic surfactants as co-templates with Cetrimonium bromide to control the mesopore diameter of hollow mesoporous silica nanoparticles (HMSN), and evaluate its influence through various experiments and analysis. The results of this study are of great importance in the field of drug delivery.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2022)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Synaptic Acid Encapsulated with Selenium-Mesoporous Silica Nanocomposite: A Potential Drug in Treating Cardiovascular Disease

Xiuping Bi et al.

Summary: A new drug delivery system using a nanocomposite was developed to enhance therapeutic potential in treating cardiovascular disease. The stable and sustainable drug release capacity of the nanocomposite reduced reactive oxygen species stress and showed promising effects in lowering low-density lipoprotein levels. Overall, this novel drug delivery platform exhibited no side effects and has the potential to improve treatment outcomes for cardiovascular disease.

JOURNAL OF CLUSTER SCIENCE (2021)

添加到收藏夹

Article Biophysics

Targeted delivery of curcumin in breast cancer cells via hyaluronic acid modified mesoporous silica nanoparticle to enhance anticancer efficiency

Shatadal Ghosh et al.

Summary: Curcumin, a natural antioxidant, was delivered through Mesoporous silica nanoparticles to enhance its anticancer efficacy by targeting cancer cells with hyaluronic acid. The synthesized nanohybrid showed cell death in MDA-MB-231 cells and decreased tumor volume in tumor-bearing mice by inducing ROS, cell cycle arrest, and modulation of apoptotic pathways. Overall, the study found that the nanohybrid had increased anticancer efficacy compared to free curcumin.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

添加到收藏夹

Article Chemistry, Physical

Hierarchical dual-porous hydroxyapatite doped dendritic mesoporous silica nanoparticles based scaffolds promote osteogenesis in vitro and in vivo

Chang Lei et al.

Summary: This study demonstrates the fabrication of hydroxyapatite-dendritic mesoporous silica nanoparticles based scaffolds for bone regeneration, showing excellent biocompatibility and osteogenic potential both in vitro and in vivo. The hierarchical pore structure of the scaffolds provides a promising approach for bone tissue engineering.

NANO RESEARCH (2021)

添加到收藏夹

Article Instruments & Instrumentation

A safety, tolerability, and pharmacokinetic study of a novel simvastatin silica-lipid hybrid formulation in healthy male participants

Tahlia R. Meola et al.

Summary: The study demonstrated that SLH formulations significantly enhanced the bioavailability of SIM, particularly SIMA, compared to a commercial formulation. SLH formulations have the potential for dose reduction and improving the bioavailability of poorly water-soluble drugs.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2021)

添加到收藏夹

Article Engineering, Biomedical

Nanoceria provides antioxidant and osteogenic properties to mesoporous silica nanoparticles for osteoporosis treatment

Alessandra Pinna et al.

Summary: Ce@MSNs, as ROS-scavenger nanoceria, showed potential in treating osteoporosis by inducing mineralisation in pre-osteoblasts and exhibiting antioxidant capability without altering cell viability significantly. The nanoparticles also stimulated cell proliferation and osteogenic responses, indicating their potential for treating diseases caused by oxidative stress.

ACTA BIOMATERIALIA (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Safe Nanoparticles: Are We There Yet?

Wided Najahi-Missaoui et al.

Summary: The field of nanotechnology has rapidly grown over the past two decades, leading to the emergence of nanoparticles as promising tools in various applications. However, questions about the toxicity and safety of nanoparticles remain unanswered, despite efforts to understand them. Several approaches to minimize and prevent nanoparticle toxicity have been identified through research.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Synthesis and Characterization of Mesoporous Mg- and Sr-Doped Nanoparticles for Moxifloxacin Drug Delivery in Promising Tissue Engineering Applications

Georgia K. Pouroutzidou et al.

Summary: Mesoporous silica-based nanoparticles (MSNs) co-doped with Ca, Mg and Sr were synthesized and characterized, showing promising drug loading properties and promoting bone formation and cell proliferation in simulated body fluid. The study also assessed their drug release profiles and biological effects on human periodontal ligament fibroblasts.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Article Engineering, Biomedical

Surface functionalized mesoporous silica nanoparticles for intravitreal application of tacrolimus

Mayara Rodrigues Brandao Paiva et al.

Summary: The study successfully incorporated tacrolimus into functionalized silica nanoparticles, which showed good biocompatibility in vitro and on chorioallantoic membrane (CAM) in vivo. Intravitreal injection of MSNAPTES TAC nanoparticles did not cause any adverse effects on rat eyes, suggesting its safety for ocular drug delivery.

JOURNAL OF BIOMATERIALS APPLICATIONS (2021)

添加到收藏夹

Article Materials Science, Biomaterials

Biodegradable nanocarriers based on chitosan-modified mesoporous silica nanoparticles for delivery of methotrexate for application in breast cancer treatment

Zahra Shakeran et al.

Summary: Nanocarriers, specifically mesoporous silica nanoparticles (MSNs), have shown great potential in delivering hydrophobic drugs like methotrexate (MTX) to tumor spaces. Surface-modified MSNs were loaded with MTX and studied for their drug release, cellular uptake and cytotoxic effects on breast cancer cells, showing promising results at a low dose.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Mesoporous silica incorporated PCL/Curcumin nanofiber for wound healing application

Saranya Rathinavel et al.

Summary: The composite nanoscaffold prepared through electrospinning shows potential for wound healing therapy, with high biocompatibility and antimicrobial properties, excellent cell adhesion, and achieving a 99% scar-less wound healing rate within 21 days in in vivo experiments.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

添加到收藏夹

Article Chemistry, Applied

Biocompatibility and internalization assessment of bare and functionalised mesoporous silica nanoparticles

Iris Garrido-Cano et al.

Summary: Mesoporous silica nanoparticles (MSNs) are efficiently internalized by human cells, with uptake mechanisms differing among cell types and particles. These biocompatible materials do not induce ROS/RNS production, nor affect mitochondrial membrane potential or cell cycle within cells.

MICROPOROUS AND MESOPOROUS MATERIALS (2021)

添加到收藏夹

Article Chemistry, Physical

Silica-based microspheres with aluminum-iron oxide shell for diagnosis and cancer treatment

M. Todea et al.

Summary: Monodispersed silica-based microspheres were prepared by hydrolysis and condensation of tetraethoxysilane, and core-shell samples were produced with iron oxide embedded in the shell for contrast enhancement in magnetic resonance imaging and local cancer treatment. SEM/TEM analysis confirmed the spherical shape of silica particles and the distribution of the shell.

JOURNAL OF MOLECULAR STRUCTURE (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Effect of Quercetin-Loaded Mesoporous Silica Nanoparticles on Myocardial Ischemia-Reperfusion Injury in Rats and Its Mechanism

Chen-Jie Liu et al.

Summary: The study demonstrated that mesoporous silica nanoparticles loaded with quercetin can significantly improve myocardial ischemia-reperfusion injury in rats by activating the JAK2/STAT3 pathway, inhibiting cell apoptosis and oxidative stress, reducing myocardial infarction size, improving ventricular remodeling, and promoting cardiac function recovery.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

添加到收藏夹

Article Chemistry, Physical

Engineering of dendritic mesoporous silica nanoparticles for efficient delivery of water-insoluble paclitaxel in cancer therapy

Chao Deng et al.

Summary: This study developed an intelligent nanocarrier drug delivery system that can highly load water-insoluble drugs and possess desirable tumor-targeting properties for cancer therapy. The nanocarriers exhibit accumulation ability on tumor cells both in vitro and in vivo, showing great promise for the efficient delivery of hydrophobic drugs and tumor treatment.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

添加到收藏夹

Article Chemistry, Applied

Mesoporous silica nanoparticle: Heralding a brighter future in cancer nanomedicine

Milad Abbasi et al.

Summary: In recent years, clinical oncology has been focused on designing targeted delivery technologies to optimize the medical response to tumor disease by delivering antitumor medicines and diagnostic agents to tumor sites. Localized delivery of medicines and diagnostic agents is essential to enhance treatment effectiveness and minimize adverse effects in cancer therapy.

MICROPOROUS AND MESOPOROUS MATERIALS (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

pH-dependent delivery of chlorhexidine from PGA grafted mesoporous silica nanoparticles at resin-dentin interface

Zohaib Akram et al.

Summary: The study synthesized and characterized chlorhexidine-loaded mesoporous silica nanoparticles grafted with poly-L-glycolic acid, and tested their in vitro drug release, cytotoxicity, and antimicrobial capacity in different pH environments. The experimental nanoparticles demonstrated low cytotoxicity and high antibacterial efficacy, showing potential for use in adhesive and restorative dentistry.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

添加到收藏夹

Article Engineering, Biomedical

Hollow Mesoporous Silica Nanoparticles Gated by Chitosan-Copper Sulfide Composites as Theranostic Agents for the Treatment of Breast Cancer

Shiwei Niu et al.

Summary: The study encapsulated the anticancer drug doxorubicin (DOX) in chitosan (CS)-modified hollow mesoporous silica nanoparticles (HMSNs), with CuS nanodots generating energy under near infrared laser (NIR) irradiation to accelerate drug release, achieving targeted drug delivery to the tumor microenvironment while demonstrating excellent photothermal therapy and dual-imaging properties.

ACTA BIOMATERIALIA (2021)

添加到收藏夹

Article Engineering, Biomedical

Effective and safe delivery of GLP-1AR and FGF-21 plasmids using amino-functionalized dual-mesoporous silica nanoparticles in vitro and in vivo

Shan Geng et al.

Summary: The use of amino-functionalized and embedded dual-mesoporous silica nanoparticles (N-EDMSNs) to simultaneously carry liraglutide and FGF-21 resulted in significant biological effects in high-fat diet fed mice, including reduced food intake, body weight, and blood glucose, increased energy expenditure and improved hepatic insulin resistance.

BIOMATERIALS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Preparation and in-vitro evaluation of mesoporous biogenic silica nanoparticles obtained from rice and wheat husk as a biocompatible carrier for anti-cancer drug delivery

Sahar Porrang et al.

Summary: Mesoporous silica nanocarriers were synthesized from natural sources such as rice and wheat husk and their morphological and physicochemical properties were investigated. The drug release behavior showed higher efficiency at acidic pH values, especially for nanocarriers synthesized by discrete mode. The Dox-loaded nanocarriers exhibited high-efficiency anticancer effect on the MCF-7 cell line within acceptable toxicity limits and apoptosis induction.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

添加到收藏夹

Editorial Material Nanoscience & Nanotechnology

Clinical translation of silica nanoparticles

Taskeen Iqbal Janjua et al.

Summary: Silica nanoparticles have shown promising safety, efficacy, and viability in clinical trials for various biomedical applications such as oral drug delivery, diagnostics, and therapy, indicating their potential in the field.

NATURE REVIEWS MATERIALS (2021)

添加到收藏夹

Article Engineering, Environmental

Subacute toxicity of mesoporous silica nanoparticles to the intestinal tract and the underlying mechanism

Yu-Di Deng et al.

Summary: This study investigated the subacute toxicity of mesoporous silica nanoparticles (MSNs) in mice and found that they induced intestinal oxidative stress, apoptosis in colonic epithelial cells, mitochondrial damage, and alterations in intestinal flora composition. Additionally, MSNs affected the expression of metabolites involved in various metabolic pathways. These results suggest that the subacute toxicity of MSNs is mainly due to intestinal damage.

JOURNAL OF HAZARDOUS MATERIALS (2021)

添加到收藏夹

Article Chemistry, Analytical

Nanoplatform based on GSH-responsive mesoporous silica nanoparticles for cancer therapy and mitochondrial targeted imaging

Hang He et al.

Summary: The study developed a mitochondrial-targeted drug delivery system which can release drugs in a GSH-dependent manner and achieve near-infrared fluorescence imaging of mitochondria. This system shows promising activity in anti-tumor therapy.

MICROCHIMICA ACTA (2021)

添加到收藏夹

Article Medicine, General & Internal

Use of Ultrasmall Core-Shell Fluorescent Silica Nanoparticles for Image-Guided Sentinel Lymph Node Biopsy in Head and Neck Melanoma A Nonrandomized Clinical Trial

Daniella Karassawa Zanoni et al.

Summary: This nonrandomized clinical trial evaluates whether an ultrasmall, molecularly targeted core-shell silica nanoparticle can safely and reliably identify optically avid SLNs in head and neck melanoma during fluorescence-guided biopsy. The study found that nanoparticle-based fluorescence-guided SLN biopsy in head and neck melanoma was feasible and safe, offering promise for improving lymphatic mapping and SLN biopsy procedures.

JAMA NETWORK OPEN (2021)

添加到收藏夹

Article Engineering, Biomedical

Carboxyl-functionalized mesoporous silica nanoparticles for the controlled delivery of poorly water-soluble non-steroidal anti-inflammatory drugs

Kaijun Gou et al.

Summary: This study aimed to investigate the delivery of poorly water-soluble non-steroidal antiinflammatory drugs (NSAIDs) by carboxyl-functionalized mesoporous silica nanoparticles (MSN-COOH) with high specific surface area. The results showed that MSN-COOH had high drug loading capacity and exhibited good in vitro drug release properties, leading to improved bioavailability and strong anti-inflammatory effects in vivo.

ACTA BIOMATERIALIA (2021)

添加到收藏夹

Article Chemistry, Applied

Chitosan-glucuronic acid conjugate coated mesoporous silica nanoparticles: A smart pH-responsive and receptor-targeted system for colorectal cancer therapy

Reema Narayan et al.

Summary: The study developed glycosylated pH-sensitive mesoporous silica nanoparticles for targeting colorectal cancer, which showed high drug loading capacity and controlled drug release, demonstrating promising antitumor efficacy in vitro with reduced toxicity.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹

Article Chemistry, Physical

Tannic acid/Fe3+complex coated mesoporous silica nanoparticles for controlled drug release and combined chemo-photothermal therapy

Qiao Shi et al.

Summary: A tannic acid/Fe3+ complex coated mesoporous silica nanoparticle (MSN-pTA) for combinational chemo-photothermal therapy was developed, showing high drug loading efficiency and stability. In animal studies, the nanoparticle combined with laser treatment demonstrated significant anti-tumor efficacy, highlighting its potential for cancer treatment.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment

Alba Garcia-Fernandez et al.

Summary: The new mesoporous silica nanoparticles-based nanodevice can target lung inflammation and reduce cytokine levels, showing promising anti-inflammatory effects in an ALI mouse model, which could be used for improving ALI treatment methods.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Nanotechnology based drug delivery system: Current strategies and emerging therapeutic potential for medical science

Tarun Sahu et al.

Summary: Nanotechnology, particularly in the field of nanomedicine, has been recognized as a key technology for improving healthcare strategies, especially in drug delivery. Living cells play crucial roles in biological activities, and nanotechnology has been widely utilized in the medical industry with significant potential for future developments in human health.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Osteoporosis Remission and New Bone Formation with Mesoporous Silica Nanoparticles

Patricia Mora-Raimundo et al.

Summary: Nanotechnology plays a crucial role in the treatment of osteoporosis by delivering siRNA through mesoporous silica nanoparticles, promoting bone formation and improving bone microarchitecture, effectively treating osteoporosis.

ADVANCED SCIENCE (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Ru(II) Polypyridine Complex-Functionalized Mesoporous Silica Nanoparticles as Photosensitizers for Cancer Targeted Photodynamic Therapy

Johannes Karges et al.

Summary: Mesoporous silica nanoparticles conjugated with folic acid can achieve better cancer cell targeted treatment, showing high potential for application.

ACS APPLIED BIO MATERIALS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Near-infrared inorganic nanomaterial-based nanosystems for photothermal therapy

Yufei Wang et al.

Summary: This review focuses on the latest developments of inorganic nanomaterials in photothermal therapy, including the light-to-heat conversion mechanism, common types of inorganic nanomaterials, and the strategy of developing multifunctional nano-platforms.

NANOSCALE (2021)

添加到收藏夹

Article Materials Science, Biomaterials

Design and Development of Sustained Release Vildagliptin-Loaded Silica Nanoparticles for Enhancing Oral Bioavailability

Nitin Rajendra Shirsath et al.

Summary: This study involved the design, optimization, and development of vildagliptin-loaded silica nanoparticles for sustained drug delivery. By utilizing a response surface methodology, the study successfully reduced the problem of frequent dosing and improved the oral bioavailability of vildagliptin.

BIONANOSCIENCE (2021)

添加到收藏夹

Review Medicine, Research & Experimental

Nanotechnology and its use in imaging and drug delivery (Review)

Serjay Sim et al.

Summary: Nanotechnology exploits the unique properties of materials at the nanoscale, and has gained popularity in various industries. Nanomedicine, the application of nanotechnology in medicine and healthcare, has been used to combat common diseases with recent advances in imaging and drug delivery.

BIOMEDICAL REPORTS (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Mesoporous silica nanoparticles functionalized with folic acid for targeted release Cis-Pt to glioblastoma cells

Emma Ortiz-Islas et al.

Summary: This study reported the preparation, characterization, and drug release study of mesoporous silica nanoparticles functionalized with folic acid for targeted release of Cis-Pt to kill glioblastoma cancer cells. The MNPSiO2 showed high surface area, large pore size, and proper functionalization, with Higuchi model fitting better to the experimental results. The MNPSiO2-FA were highly biocompatible and enhanced the cytotoxic effect of Cis-Pt.

REVIEWS ON ADVANCED MATERIALS SCIENCE (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

One-Pot Synthesis of pH-Responsive Eudragit-Mesoporous Silica Nanocomposites Enable Colonic Delivery of Glucocorticoids for the Treatment of Inflammatory Bowel Disease

Zhi Qu et al.

Summary: The study proposes a smart drug delivery system using functionalized mesoporous silica nanoparticles and pH-responsive polymer to improve the release efficiency and reduce systemic side effects of oral glucocorticoids. Results show that this system can release drugs at colonic pH and demonstrate therapeutic efficacy in a mouse colitis model. Coated nanoparticles significantly decrease cytokine expression in the proximal colon, indicating colonic delivery effectiveness.

ADVANCED THERAPEUTICS (2021)

添加到收藏夹

Article Biophysics

Multi-stimuli responsive mesoporous silica-coated carbon nanoparticles for chemo-photothermal therapy of tumor

Hongyan Lu et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Effects of miR-26a on Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by a Mesoporous Silica Nanoparticle - PEI - Peptide System

Jia Yan et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Superiority of L-tartaric Acid Modified Chiral Mesoporous Silica Nanoparticle as a Drug Carrier: Structure, Wettability, Degradation, Bio-Adhesion and Biocompatibility

Beibei Hu et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

添加到收藏夹

Article Optics

Lanthanide-sensitized luminescence and chemiluminescence in the systems containing most often used medicines; a review

Malgorzata Kaczmarek

JOURNAL OF LUMINESCENCE (2020)

添加到收藏夹

Article Chemistry, Applied

Fabrication and characterization of bioactive chitosan microspheres incorporated with mesoporous silica nanoparticles for biomedical applications

A. M. Hezma et al.

JOURNAL OF POROUS MATERIALS (2020)

添加到收藏夹

Article Medicine, Research & Experimental

Folic acid (FA)-conjugated mesoporous silica nanoparticles combined with MRP-1 siRNA improves the suppressive effects of myricetin on non-small cell lung cancer (NSCLC)

Song Yinxue et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Incorporation of dexamethasone-loaded mesoporous silica nanoparticles into mineralized porous biocomposite scaffolds for improving osteogenic activity

Xiaojun Zhou et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Article Chemistry, Physical

Super-assembled core-shell mesoporous silica-metal-phenolic network nanoparticles for combinatorial photothermal therapy and chemotherapy

Bo Yang et al.

NANO RESEARCH (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Intra-articular delivery of celastrol by hollow mesoporous silica nanoparticles for pH-sensitive anti-inflammatory therapy against knee osteoarthritis

Tian Jin et al.

JOURNAL OF NANOBIOTECHNOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Highly ordered functionalized mesoporous silicate nanoparticles reinforced poly (lactic acid) gatekeeper surface for infection treatment

Mostafa F. Abdelbar et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Article Materials Science, Multidisciplinary

Reactive oxygen species-sensitive thioketal-linked mesoporous silica nanoparticles as drug carrier for effective antibacterial activity

Jinsong Li et al.

MATERIALS & DESIGN (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Improvement of mesoporous silica nanoparticles: A new approach in the administration of NSAIDS

Elena Ortega et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

添加到收藏夹

Review Materials Science, Multidisciplinary

Role of mesoporous silica nanoparticles for the drug delivery applications

Baranya Murugan et al.

MATERIALS RESEARCH EXPRESS (2020)

添加到收藏夹

Review Nanoscience & Nanotechnology

Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications

Jonas G. Croissant et al.

NATURE REVIEWS MATERIALS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Colchicine mesoporous silica nanoparticles/hydrogel composite loaded cotton patches as a new encapsulator system for transdermal osteoarthritis management

Amina L. Mohamed et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Controlled Tyrosine Kinase Inhibitor Delivery to Liver Cancer Cells by Gate-Capped Mesoporous Silica Nanoparticles

Mahsa Sedighi et al.

ACS APPLIED BIO MATERIALS (2020)

添加到收藏夹

Article Materials Science, Multidisciplinary

Development of glycyrrhizin-conjugated, chitosan-coated, lysine-embedded mesoporous silica nanoparticles for hepatocyte-targeted liver tissue regeneration

Yung-Te Hou et al.

MATERIALIA (2020)

添加到收藏夹

Article Engineering, Biomedical

Design and fabrication of electrospun SBA-15-incorporated PVA with curcumin: a biomimetic nanoscaffold for skin tissue engineering

Saranya Rathinavel et al.

BIOMEDICAL MATERIALS (2020)

添加到收藏夹

Review Engineering, Environmental

Mesoporous silica nanoparticles: Synthesis, pharmaceutical applications, biodistribution, and biosafety assessment

Fatemeh Farjadian et al.

CHEMICAL ENGINEERING JOURNAL (2019)

添加到收藏夹

Review Nanoscience & Nanotechnology

A review of small molecules and drug delivery applications using gold and iron nanoparticles

Hossein Jahangirian et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Codelivery of Plasmid and Curcumin with Mesoporous Silica Nanoparticles for Promoting Neurite Outgrowth

Cheng-Shun Cheng et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Review Pharmacology & Pharmacy

New insights towards mesoporous silica nanoparticles as a technological platform for chemotherapeutic drugs delivery

Rafael M. Sabio et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enzyme-/Redox-Responsive Mesoporous Silica Nanoparticles Based on Functionalized Dopamine as Nanocarriers for Cancer Therapy

Dandan Zhu et al.

ACS OMEGA (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Ratiometric Imaging of the in Situ pH Distribution of Biofilms by Use of Fluorescent Mesoporous Silica Nanosensors

Stephanie Fulaz et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Review Pharmacology & Pharmacy

Solid Lipid Nanoparticles: A Promising Nanomaterial in Drug Delivery

Kuldeep Rajpoot

CURRENT PHARMACEUTICAL DESIGN (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Gold nanoshell-localized photothermal ablation of prostate tumors in a clinical pilot device study

Ardeshir R. Rastinehad et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Mesoporous Silica Nanoparticles Trigger Liver and Kidney Injury and Fibrosis Via Altering TLR4/NF-κB, JAK2/STAT3 and Nrf2/HO-1 Signaling in Rats

Ayman M. Mahmoud et al.

BIOMOLECULES (2019)

添加到收藏夹

Review Pharmacology & Pharmacy

Nanocarrier-based systems for targeted and site specific therapeutic delivery

Joydeb Majumder et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

添加到收藏夹

Article Engineering, Biomedical

Lectin-conjugated pH-responsive mesoporous silica nanoparticles for targeted bone cancer treatment

Marina Martinez-Carmona et al.

ACTA BIOMATERIALIA (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

I-131 doping of silver nanoparticles platform for tumor theranosis guided drug delivery

Tamer M. Sake et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2018)

添加到收藏夹

Article Nanoscience & Nanotechnology

Targeted delivery of anti-miR-155 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy

Yang Li et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Mesoporous silicate nanoparticles/3D nanofibrous scaffold-mediated dual-drug delivery for bone tissue engineering

Qingqing Yao et al.

JOURNAL OF CONTROLLED RELEASE (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Etoposide encapsulated functionalized mesoporous silica nanoparticles: Synthesis, characterization and effect of functionalization on dissolution kinetics in simulated and biorelevant media

Seema Saroj et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2018)

添加到收藏夹

Article Chemistry, Applied

Chitosan grafted into mesoporous silica nanoparticles as benznidazol carrier for Chagas diseases treatment

Egidio Paulo Francisco Nhavene et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2018)

添加到收藏夹

Article Engineering, Biomedical

Biological Stimulus-Driven Assembly/Disassembly of Functional Nanoparticles for Targeted Delivery, Controlled Activation, and Bioelimination

Xi Hu et al.

ADVANCED HEALTHCARE MATERIALS (2018)

添加到收藏夹

Article Cell Biology

Sustained Release of IGF-1 by 3D Mesoporous Scaffolds Promoting Cardiac Stem Cell Migration and Proliferation

Yuning Sun et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)

添加到收藏夹

Review Biotechnology & Applied Microbiology

The toxicity of silica nanoparticles to the immune system

Liangjiao Chen et al.

NANOMEDICINE (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Mesoporous silica nanoparticles engineered for ultrasound-induced uptake by cancer cells

Juan L. Paris et al.

NANOSCALE (2018)

添加到收藏夹

Proceedings Paper Materials Science, Multidisciplinary

Nanotechnology and Nanomedicine: Start small, think big

Saeid Kargozar et al.

MATERIALS TODAY-PROCEEDINGS (2018)

添加到收藏夹

Article Chemistry, Applied

Multifunctional mesoporous silica nanoparticles for cancer-targeted, controlled drug delivery and imaging

Luiza Baptista de Oliveira Freitas et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2017)

添加到收藏夹

Article Nanoscience & Nanotechnology

Lectin-functionalized mesoporous silica nanoparticles for endoscopic detection of premalignant colonic lesions

Nai-Tzu Chen et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2017)

添加到收藏夹

Article Materials Science, Biomaterials

Gelatin-functionalized mesoporous silica nanoparticles with sustained release properties for intracameral pharmacotherapy of glaucoma

Yu-Te Liao et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Plasmonic photothermal therapy of atherosclerosis with nanoparticles: long-term outcomes and safety in NANOM-FIM trial

Alexander N. Kharlamov et al.

FUTURE CARDIOLOGY (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Multifunctional silica nanoparticles as a promising theranostic platform for biomedical applications

Zhigang Xu et al.

MATERIALS CHEMISTRY FRONTIERS (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Degradability and Clearance of Silicon, Organosilica, Silsesquioxane, Silica Mixed Oxide, and Mesoporous Silica Nanoparticles

Jonas G. Croissant et al.

ADVANCED MATERIALS (2017)

添加到收藏夹

Article Nanoscience & Nanotechnology

Nanotherapeutics of PTEN Inhibitor with Mesoporous Silica Nanocarrier Effective for Axonal Outgrowth of Adult Neurons

Min Soo Kim et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

添加到收藏夹

Article Pharmacology & Pharmacy

Ordered mesoporous silica to enhance the bioavailability of poorly water-soluble drugs: Proof of concept in man

Katarina Bukara et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2016)

添加到收藏夹

Article Engineering, Biomedical

Programmed packaging of mesoporous silica nanocarriers for matrix metalloprotease 2-triggered tumor targeting and release

Zhen Zou et al.

BIOMATERIALS (2015)

添加到收藏夹

Article Pharmacology & Pharmacy

Surface functionalized mesoporous silica nanoparticles as an effective carrier for epirubicin delivery to cancer cells

Mohammad Yahya Hanafi-Bojd et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2015)

添加到收藏夹

Review Chemistry, Multidisciplinary

Applications of Magnetic Nanoparticles in Targeted Drug Delivery System

Xianbo Mou et al.

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Silica-gold nanoparticles for atheroprotective management of plaques: results of the NANOM-FIM trial

Alexander N. Kharlamov et al.

NANOSCALE (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Single-micelle-templated synthesis of hollow silica nanospheres with tunable pore structures

Yingyu Li et al.

RSC ADVANCES (2015)

添加到收藏夹

Review Pharmacology & Pharmacy

Mesoporous silica nanoparticles in target drug delivery system: A review

Charu Bharti et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION (2015)

添加到收藏夹

Review Chemistry, Multidisciplinary

Hollow-Structured Mesoporous Materials: Chemical Synthesis, Functionalization and Applications

Yongsheng Li et al.

ADVANCED MATERIALS (2014)

添加到收藏夹

Article Chemistry, Applied

Hollow mesoporous silica nanoparticles with tunable shell thickness and pore size distribution for application as broad-ranging pH nanosensor

Chieh-Jui Tsou et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2014)

添加到收藏夹

Article Cell Biology

Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

Evan Phillips et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

添加到收藏夹

Article Instruments & Instrumentation

First in man bioavailability and tolerability studies of a silica-lipid hybrid (Lipoceramic) formulation: a Phase I study with ibuprofen

Angel Tan et al.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2014)

添加到收藏夹

Review Chemistry, Multidisciplinary

Metabolism of Nanomaterials in Vivo: Blood Circulation and Organ Clearance

Bing Wang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2013)

添加到收藏夹

Review Pharmacology & Pharmacy

Inorganic nanosystems for therapeutic delivery: Status and prospects

Chang Soo Kim et al.

ADVANCED DRUG DELIVERY REVIEWS (2013)

添加到收藏夹

Review Chemistry, Multidisciplinary

Porous Nanosized Particles: Preparation, Properties, and Applications

Valentin Valtchev et al.

CHEMICAL REVIEWS (2013)

添加到收藏夹

Review Chemistry, Multidisciplinary

Synthesis of mesoporous silica nanoparticles

Si-Han Wu et al.

CHEMICAL SOCIETY REVIEWS (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Nanocarriers for Anticancer Drugs - New Trends in Nanomedicine

Jana Drbohlavova et al.

CURRENT DRUG METABOLISM (2013)

添加到收藏夹

Review Chemistry, Multidisciplinary

Biocompatibility of engineered nanoparticles for drug delivery

Sheva Naahidi et al.

JOURNAL OF CONTROLLED RELEASE (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Folic acid-functionalized mesoporous silica nanospheres hybridized with AIE luminogens for targeted cancer cell imaging

Zilong Wang et al.

NANOSCALE (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Collagen gel combined with mesoporous nanoparticles loading nerve growth factor as a feasible therapeutic three-dimensional depot for neural tissue engineering

Jae Ho Lee et al.

RSC ADVANCES (2013)

添加到收藏夹

Review Chemistry, Multidisciplinary

Magnetic mesoporous silica-based core/shell nanoparticles for biomedical applications

Nikola Z. Knezevic et al.

RSC ADVANCES (2013)

添加到收藏夹

Article Cell & Tissue Engineering

Silica-based mesoporous nanoparticles for controlled drug delivery

Sooyeon Kwon et al.

JOURNAL OF TISSUE ENGINEERING (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Near-Infrared Light-Triggered, Targeted Drug Delivery to Cancer Cells by Aptamer Gated Nanovehicles

Xinjian Yang et al.

ADVANCED MATERIALS (2012)

添加到收藏夹

Review Chemistry, Multidisciplinary

Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery

Fangqiong Tang et al.

ADVANCED MATERIALS (2012)

添加到收藏夹

Review Chemistry, Medicinal

Biocompatibility of Mesoporous Silica Nanoparticles

Tewodros Asefa et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2012)

添加到收藏夹

Review Nanoscience & Nanotechnology

Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging

Suphiya Parveen et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2012)

添加到收藏夹

Review Chemistry, Physical

A Review: Fundamental Aspects of Silicate Mesoporous Materials

Zeid A. ALOthman

MATERIALS (2012)

添加到收藏夹

Review Chemistry, Multidisciplinary

Theranostic Nanoparticles Engineered for Clinic and Pharmaceutics

Xiaowei Ma et al.

ACCOUNTS OF CHEMICAL RESEARCH (2011)

添加到收藏夹

Article Chemistry, Physical

Synthesis and characterization of pore size-tunable magnetic mesoporous silica nanoparticles

Jixi Zhang et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2011)

添加到收藏夹

Article Chemistry, Multidisciplinary

In Vivo Biodistribution and Clearance Studies Using Multimodal Organically Modified Silica Nanoparticles

Rajiv Kumar et al.

ACS NANO (2010)

添加到收藏夹

Review Chemistry, Multidisciplinary

Modern Views on Desilicification: Biosilica and Abiotic Silica Dissolution in Natural and Artificial Environments

Hermann Ehrlich et al.

CHEMICAL REVIEWS (2010)

添加到收藏夹

Article Chemistry, Multidisciplinary

Impacts of Mesoporous Silica Nanoparticle Size, Pore Ordering, and Pore Integrity on Hemolytic Activity

Yu-Shen Lin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

添加到收藏夹

Article Chemistry, Multidisciplinary

Synthesis of hollow silica nanospheres with a microemulsion as the template

Yu-Shen Lin et al.

CHEMICAL COMMUNICATIONS (2009)

添加到收藏夹

Review Chemistry, Multidisciplinary

Mesoporous materials for encapsulating enzymes

Chia-Hung Lee et al.

NANO TODAY (2009)

添加到收藏夹

Review Polymer Science

Thermo-sensitive polymeric micelles based on poly(N-isopropylacrylamide) as drug carriers

Hua Wei et al.

PROGRESS IN POLYMER SCIENCE (2009)

添加到收藏夹

Review Pharmacology & Pharmacy

Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers

Igor I. Slowing et al.

ADVANCED DRUG DELIVERY REVIEWS (2008)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Silica-based multimodal/multifunctional nanoparticles for bioimaging and biosensing applications

Padmavathy Tallury et al.

NANOMEDICINE (2008)

添加到收藏夹

Article Chemistry, Multidisciplinary

Simple synthesis of functionalized superparamagnetic magnetite/silica core/shell nanoparticles and their application as magnetically separable high-performance biocatalysts

Jinwoo Lee et al.

SMALL (2008)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Mesoporous silica nanomaterial-based biotechnological and biomedical delivery systems

Supratim Giri et al.

NANOMEDICINE (2007)

添加到收藏夹

Review Chemistry, Multidisciplinary

Synthesis and functionalization of a mesoporous silica nanoparticle based on the sol-gel process and applications in controlled release

Brian G. Trewyn et al.

ACCOUNTS OF CHEMICAL RESEARCH (2007)

添加到收藏夹

Article Chemistry, Physical

Mesoporous silica spheres as supports for enzyme immobilization and encapsulation

YJ Wang et al.

CHEMISTRY OF MATERIALS (2005)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.