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Ji-Hye Yoon et al.
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Takuya Konno et al.
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High nigral iron deposition in LRRK2 and Parkin mutation carriers using R2*relaxometry
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C-Y Chen et al.
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Dejun Yang et al.
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Dependence of Leucine-rich Repeat Kinase 2 (LRRK2) Kinase Activity on Dimerization
Saurabh Sen et al.
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Sneha Ramesh et al.
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Gene and protein signatures in sporadic Parkinson's disease and a novel genetic model of PD
Silvia A. Mandel et al.
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The familial parkinsonism gene LRRK2 regulates neurite process morphology
David MacLeod et al.
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Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells
J Riemer et al.
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Striatal 6-hydroxydopamine induces apoptosis of nigral neurons in the adult rat
MJ Martí et al.
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