期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 24, 期 5, 页码 -出版社
MDPI
DOI: 10.3390/ijms24054965
关键词
silkworm strain; cocoon; silk fibroin; degumming; structural characteristics; mechanical properties
This study investigated the structural characteristics and properties of silkworm cocoons and silk fibroins (SFs) from ten different silkworm strains. The morphological structure of the cocoons varied depending on the silkworm strains. The degumming ratio of silk ranged from 22.8% to 28%, and the solution viscosities of SFs showed a 12-fold difference. The mechanical properties of the regenerated SF film were significantly influenced by the silkworm strains.
Silk has attracted the attention of researchers as a biomedical and cosmetic material because of its good biocompatibility and cytocompatibility. Silk is produced from the cocoons of silkworms, which have various strains. In this study, silkworm cocoons and silk fibroins (SFs) were obtained from ten silkworm strains, and their structural characteristics and properties were examined. The morphological structure of the cocoons depended on the silkworm strains. The degumming ratio of silk ranged from 22.8% to 28% depending on the silkworm strains. The highest and lowest solution viscosities of SF were shown by 9671 and 9153, respectively, showing a 12-fold difference. The silkworm strains of 9671, KJ5, and I-NOVI showed a two-fold higher work of ruptures for the regenerated SF film than 181 and 2203, indicating that the silkworm strains considerably influence the mechanical properties of the regenerated SF film. Regardless of the silkworm strain, all silkworm cocoons showed good cell viability, making them suitable candidates for advanced functional biomaterials.
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