☆ 4.5 Review

Associated factors for postoperative delirium following major abdominal surgery: A systematic review and meta-analysis

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2023)

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Summary: This integrative review aimed to synthesize specific comorbidities that can contribute to the development of post-operative delirium in older adult cardiac surgical patients. The study identified several comorbidities, including diabetes mellitus, atrial fibrillation, depression, impaired olfaction, pre-existing cerebrovascular disease, pre-existing cardiovascular disease, insomnia, and frailty. The results strongly indicated a link between comorbidities and the development of post-operative delirium in older adult cardiac surgical patients.

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Summary: Low levels of IGF-1 are significantly associated with postoperative delirium in abdominal surgical samples, high levels of C-RP are associated with delirium in acute orthopaedic and elective abdominal operations, and IL-6 serves as a significant predictor for delirium in various surgical conditions postoperatively.

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Article Anesthesiology

Development and validation of a risk score for predicting postoperative delirium after major abdominal surgery by incorporating preoperative risk factors and surgical Apgar score

Guan-Hua Li et al.

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Risk Factors for Delirium after Vascular Surgery: A Systematic Review and Meta-Analysis

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Qi-hong Shen et al.

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Risk factors for postoperative delirium after elective major abdominal surgery in elderly patients: A cohort study

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Use of medicines that may precipitate delirium prior to hospitalisation in older Australians with delirium: An observational study

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INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2018)

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Low peripheral levels of insulin growth factor-1 are associated with high incidence of delirium among elderly patients: A systematic review and meta-analysis

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Neopterin and Mini-Mental State Examination scores, two independent risk factors for postoperative delirium in elderly patients with open abdominal surgery

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Risk Factors for Postoperative Delirium in Abdominal Surgery: A Proposal of a Postoperative Delirium Risk Score in Abdominal Surgery

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DIGESTIVE SURGERY (2017)

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Review Surgery

Systematic review and meta-analysis of risk factors for postoperative delirium among older patients undergoing gastrointestinal surgery

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Insulin-Like Growth Factor-1, a Potential Predicative Biomarker for Postoperative Delirium Among Elderly Patients with Open Abdominal Surgery

Huachun Shen et al.

CURRENT PHARMACEUTICAL DESIGN (2016)

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Lack of Association between Pre-Operative Insulin-Like Growth Factor-1 and the Risk of Post-Operative Delirium in Elderly Chinese Patients

Che-Sheng Chu et al.

PSYCHIATRY INVESTIGATION (2016)

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Risk Factors and Outcomes for Postoperative Delirium after Major Surgery in Elderly Patients

Jelle W. Raats et al.

PLOS ONE (2015)

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The impact of intra- and postoperative albumin levels as a biomarker of delirium after cardiopulmonary bypass: Results of an exploratory study

Andreas Baranyi et al.

PSYCHIATRY RESEARCH (2012)

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Boukje Koebrugge et al.

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