Electrochemical sensing monitoring of blood lactic acid levels in sweat during exhaustive exercise

Carbohydrate anaerobic metabolism in the human body produces lactic acid, which is of great importance in the diagnosis and treatment of diseases and the scientific management of sports. Consequently, the development of a rapid, low-cost, and disposable lactate sensor is essential. To this end, a graphene-modified lactate sensor was created. This work concluded with the optimization of the sensor's operating parameters and the evaluation of its performance under the optimal conditions. Following the testing, the proposed lactic acid sensor demonstrated high sensitivity, excellent consistency and linearity, with a linear detection range of 3-32 mM. The detection limit was determined to be 1.4 mM, the lowest value achieved. The current performance of the biosensor is reaching its peak when presented with physiological sweat lactate concentration. To monitor sweat lactate concentration, wearable electronic devices with high precision were incorporated to provide real-time remote monitoring. By engaging in exhaustive physical exercise, the amount of sweat lactate can be determined.

Automated summary

Carbohydrate anaerobic metabolism produces lactic acid in the human body, which plays a crucial role in disease diagnosis, treatment, and sports management. Therefore, the development of a fast, low-cost, and disposable lactate sensor is essential. Researchers created a graphene-modified lactate sensor and optimized its operating parameters. The sensor exhibited high sensitivity, excellent consistency, and linearity, with a linear detection range of 3-32 mM and a detection limit of 1.4 mM, the lowest ever achieved. Wearable electronic devices were utilized for real-time remote monitoring of sweat lactate concentration.