Synthesis, characterization, and assessment of chitosan-nanomatrix enriched with antifungal formulation against biodeterioration of active ingredients of selected herbal raw materials

Article Chemistry, Applied

A stem-loop like aptasensor for sensitive detection of aflatoxin based on graphene oxide/AuNPs nanocomposite platform

Mehdi Dadmehr et al.

Summary: A specific aptasensor for aflatoxin B1 (AFB1) detection was developed in this study, which showed high sensitivity and selectivity for detecting AFB1 in food samples.

FOOD CHEMISTRY (2023)

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Article Food Science & Technology

Aflatoxins in stored maize, maize flours, and stiff porridge consumed in schools: A case study of Dodoma region, Tanzania

Mariamu Kibwana et al.

Summary: This study aimed to evaluate the levels of total aflatoxins in stored maize, maize flour, and stiff porridge consumed in schools in Dodoma Region. The results showed that the samples of stored maize, maize flour, and stiff porridge were contaminated with aflatoxins at levels that exceeded the Maximum Tolerable Level (MTL), putting consumers at risk of aflatoxin hazards.

FOOD CONTROL (2023)

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Article Biochemistry & Molecular Biology

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

Mihaly Varadi et al.

Summary: AlphaFold DB is an openly accessible database with high-accuracy protein-structure predictions, powered by DeepMind's AlphaFold v2.0. It provides programmatic access to a vast number of predicted structures and is expanding to cover more sequences.

NUCLEIC ACIDS RESEARCH (2022)

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Article Biochemistry & Molecular Biology

Antibacterial and antibiofilm activities of chitosan nanoparticles loaded with Ocimum basilicum L. essential oil

Mingdi Cai et al.

Summary: This study demonstrates that encapsulating basil essential oil into chitosan nanoparticles can enhance its physical stability and also exhibit strong antibacterial and antibiofilm capacities.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

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Article Food Science & Technology

Nanoencapsulated plant-based antifungal formulation against the Aspergillus flavus and aflatoxin B1 contamination: Unraveling the biochemical and molecular mechanism of action

Akshay Kumar et al.

Summary: This study reports the efficacy of a nano-encapsulated plant-based antifungal formulation (Ne-CGT) in controlling Aspergillus flavus and AFB1 contamination. Ne-CGT exhibited enhanced antifungal and AFB1 activity compared to its free form. Furthermore, Ne-CGT effectively preserved the nutrition properties of the crops.

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2022)

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Article Engineering, Environmental

Unravelling the pathways of air plasma induced aflatoxin B1 degradation and detoxification

Natasa Hojnik et al.

Summary: Aflatoxins, particularly AFB(1), are a major dietary risk factor for humans, with the WHO identifying it as a potent carcinogen. This study demonstrates an efficient targeted degradation of AFB(1) using non-equilibrium plasma, with detailed mechanisms elucidated through sensitive analytical methods. The approach not only renders AFB(1) harmless in a short amount of time, but also outperforms other non-thermal methods like UV irradiation.

JOURNAL OF HAZARDOUS MATERIALS (2021)

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Review Medicine, Research & Experimental

Exploring the multifocal role of phytochemicals as immunomodulators

Tapan Behl et al.

Summary: The well-functioning immune system of the host body is crucial for maintaining normal physiological and immunological functions, as well as the internal environment. Balancing immunity enhances defense mechanisms against infections, diseases, and unwanted pathogens to prevent hypersensitivity reactions and immune-related diseases. Recent interest in the immune system as a significant target for toxicity has increased due to exposure to chemicals, drugs, and environmental pollutants. Various factors such as sex, age, stress, malnutrition, alcohol, genetic variability, lifestyles, environmental pollutants, and chemotherapy exposure can alter immune responses. Immunomodulation involves modifying immune responses through induction, amplification, attenuation, or inhibition. Phytochemicals, including glycosides, alkaloids, phenolic acids, flavonoids, saponins, tannins, sterols, and sterolins, play a key role in modulating favorable immune responses.

BIOMEDICINE & PHARMACOTHERAPY (2021)

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Article Biochemistry & Molecular Biology

Encapsulation of essential oils using cinnamic acid grafted chitosan nanogel: Preparation, characterization and antifungal activity

Stephanne Yonara Barbosa de Carvalho et al.

Summary: This study developed a cinnamic acid grafted chitosan nanogel capable of encapsulating essential oils and exhibiting antifungal activity, which shows potential application in controlling dermatophytosis.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Article Biochemistry & Molecular Biology

Chitosan nanoparticles encapsulating lemongrass (Cymbopogon commutatus) essential oil: Physicochemical, structural, antimicrobial and in-vitro release properties

Maral Soltanzadeh et al.

Summary: This study successfully encapsulated lemongrass essential oil into chitosan nanoparticles, forming a novel nanocomposite with antimicrobial activity and thermal stability.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Article Infectious Diseases

Nanoencapsulated Essential Oils with Enhanced Antifungal Activity for Potential Application on Agri-Food, Material and Environmental Fields

Magdalena Kapustova et al.

Summary: Nanotechnology, specifically nanoencapsulation of plant essential oils with antifungal activity, shows promise in overcoming resistance in fungal species. The essential oil nanosystems exhibited lower MIC and MFC values compared to pure essential oils, indicating their potential as ecofriendly alternatives to synthetic products.

ANTIBIOTICS-BASEL (2021)

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Article Food Science & Technology

Fabrication, Characterization, and Antifungal Assessment of Jasmine Essential Oil-Loaded Chitosan Nanomatrix Against Aspergillus flavus in Food System

Anupam Kujur et al.

Summary: The study investigated the antifungal and AFB(1) inhibitory efficacy of Jasmine essential oil-loaded in chitosan nanoparticles against Aspergillus flavus. The encapsulation efficiency and loading capacity were optimized with a 1:1 ratio of chitosan: JEO. JEO-NP showed enhanced antifungal activity and free radical scavenging, and protected maize seeds from fungal growth and aflatoxin contamination.

FOOD AND BIOPROCESS TECHNOLOGY (2021)

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Article Biochemistry & Molecular Biology

Chitosan packaging functionalized with Cinnamodendron dinisii essential oil loaded zein: A proposal for meat conservation

Leandra Oliveira Xavier et al.

Summary: The nanoencapsulation of Cinnamodendron dinisii Schwanke essential oil using zein as wall material resulted in stable and homogeneous nanoparticles with antioxidant and antimicrobial activity, which was effective in preserving ground beef by stabilizing deterioration reactions and maintaining color.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Article Biochemistry & Molecular Biology

Pesticidal efficacy, mode of action and safety limits profile of essential oils based nanoformulation against Callosobruchus chinensis and Aspergillus flavus

Amrita Yadav et al.

Summary: The study investigated the pesticidal efficacy, mode of action, and safety limit profile of an essential oils-based formulation and its nanoformulation against insects, fungi, and aflatoxin B1 production. Nanoencapsulation of the formulation showed a significant synergistic effect in inhibiting pests, fungi, and aflatoxin production. Various approaches were used to explore the detailed mode of pesticidal action and safety limit profile.

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY (2021)

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Review Biochemistry & Molecular Biology

Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and Cancer

Nishat Fatima et al.

Summary: Oxygen is essential for respiration but excess can have harmful effects. Oxidative stress leads to membrane disruption and is associated with cancer and aging. Plant-based phytochemicals are being explored as alternative treatments.

ANTIOXIDANTS (2021)

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Article Integrative & Complementary Medicine

The Synergistic Effect of Three Essential Oils against Bacteria Responsible for the Development of Lithiasis Infection: An Optimization by the Mixture Design

Rabie Kachkoul et al.

Summary: This study investigates the chemical composition and synergistic effect of essential oils from Eucalyptus camaldulensis, Mentha pulegium, and Rosmarinus officinalis against Proteus mirabilis, Klebsiella pneumoniae, and Staphylococcus aureus. Results show significant antibacterial efficacy, particularly with Mentha pulegium and Eucalyptus camaldulensis showing the best inhibition zones against the bacterial strains. The findings suggest the importance of these essential oils in treating urinary tract infections caused by resistant bacterial strains.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2021)

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Article Food Science & Technology

Antimicrobial combined action of Mentha pulegium, Ormenis mixta and Mentha piperita essential oils against S. aureus, E. coli and C. tropicalis: Application of mixture design methodology

Marwa Chraibi et al.

Summary: The study used experimental design methodology (mixture design) and microdilution assay to investigate interactions between active compounds from three Moroccan essential oils against S. aureus, E. coli, and C. tropicalis. The research found synergistic effects between M. piperita and M. pulegium essential oils and predicted optimal mixtures for combating bacterial and fungal infections. This suggests that essential oil combinations could be useful in addressing microbial drug resistance and as natural food preservatives.

LWT-FOOD SCIENCE AND TECHNOLOGY (2021)

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Article Biochemistry & Molecular Biology

Encapsulation of Bunium persicum essential oil using chitosan nanopolymer: Preparation, characterization, antifungal assessment, and thermal stability

Amrita Yadav et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

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Article Chemistry, Applied

Chitosan nanoparticles loaded with clove essential oil: Characterization, antioxidant and antibacterial activities

Milad Hadidi et al.

CARBOHYDRATE POLYMERS (2020)

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Article Food Science & Technology

Antifungal and aflatoxin B1 inhibitory efficacy of nanoencapsulated Pelargonium graveolens L. essential oil and its mode of action

Anupam Kujur et al.

LWT-FOOD SCIENCE AND TECHNOLOGY (2020)

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Article Food Science & Technology

Assessing the antifungal and aflatoxin B1 inhibitory efficacy of nanoencapsulated antifungal formulation based on combination of Ocimum spp. essential oils

Akshay Kumar et al.

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2020)

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Article Chemistry, Applied

Improving the antifungal activity of clove essential oil encapsulated by chitosan nanoparticles

Nayeresadat Hasheminejad et al.

FOOD CHEMISTRY (2019)

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Article Chemistry, Applied

Nanoencapsulated plant-based bioactive formulation against food-borne molds and aflatoxin B1 contamination: Preparation, characterization and stability evaluation in the food system

Akshay Kumar et al.

FOOD CHEMISTRY (2019)

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Article Biochemistry & Molecular Biology

Preparation, characterization and anti-aflatoxigenic activity of chitosan packaging films incorporated with turmeric essential oil

Zheyu Li et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

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Article Agricultural Engineering

Antifungal and antiaflatoxinogenic activities of Carum carvi L., Coriandrum sativum L. seed essential oils and their major terpene component against Aspergillus flavus

Salma Lasram et al.

INDUSTRIAL CROPS AND PRODUCTS (2019)

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Article Biochemical Research Methods

New spectrophotometric assay for assessments of catalase activity in biological samples

Mahmoud Hussein Hadwan et al.

ANALYTICAL BIOCHEMISTRY (2018)

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Article Pharmacology & Pharmacy

Combined treatment of Thymus vulgaris L., Rosmarinus officinalis L. and Myrtus communis L. essential oils against Salmonella typhimurium: Optimization of antibacterial activity by mixture design methodology

Mouhcine Fadil et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2018)

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Article Food Science & Technology

Nanoencapsulation: An efficient technology to boost the antimicrobial potential of plant essential oils in food system

Bhanu Prakash et al.

FOOD CONTROL (2018)

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Article Chemistry, Applied

Mechanisms of antifungal and anti-aflatoxigenic properties of essential oil derived from turmeric (Curcuma longa L.) on Aspergillus flavus

Yichen Hu et al.

FOOD CHEMISTRY (2017)

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Article Food Science & Technology

Physicochemical characterization of chitosan nanoparticles and nanocapsules incorporated with lime essential oil and their antibacterial activity against food-borne pathogens

M. E. Sotelo-Boyas et al.

LWT-FOOD SCIENCE AND TECHNOLOGY (2017)

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Review Pharmacology & Pharmacy

The Microbial Quality Aspects and Decontamination Approaches for the Herbal Medicinal Plants and Products: An in-Depth Review

Daniela Dal Molim Ghisleni et al.

CURRENT PHARMACEUTICAL DESIGN (2016)

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Article Food Science & Technology

Assessment of preservative potential of Cinnamomum zeylanicum Blume essential oil against food borne molds, aflatoxin B1 synthesis, its functional properties and mode of action

S. Kiran et al.

INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2016)

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Article Nanoscience & Nanotechnology

Enhanced Antifungal Effect of Chitosan/Pepper Tree (Schinus molle) Essential Oil Bionanocomposites on the Viability of Aspergillus parasiticus Spores

Ana Guadalupe Luque-Alcaraz et al.

JOURNAL OF NANOMATERIALS (2016)

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Review Food Science & Technology

Plant essential oils as food preservatives to control moulds, mycotoxin contamination and oxidative deterioration of agri-food commodities - Potentials and challenges

Bhanu Prakash et al.

FOOD CONTROL (2015)

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Article Biotechnology & Applied Microbiology

Efficacy of Caesulia axillaris, Cymbopogon khasans and Cymbopogon martinii essential oils as plant based preservatives against degradation of raw materials of Andrographis paniculata by fungal spoilage

Prashant Kumar Mishra et al.

INTERNATIONAL BIODETERIORATION & BIODEGRADATION (2015)

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Article Agriculture, Multidisciplinary

Assessment of Toxicity, Antifeedant Activity, and Biochemical Responses in Stored-Grain Insects Exposed to Lethal and Sublethal Doses of Gaultheria procumbens L. Essential Oil

S. Kiran et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2015)

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Article Multidisciplinary Sciences

Structural mechanism of ergosterol regulation by fungal sterol transcription factor Upc2

Huiseon Yang et al.

NATURE COMMUNICATIONS (2015)

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Article Biotechnology & Applied Microbiology

Role of Oxidative Stress in Sclerotial Differentiation and Aflatoxin B1 Biosynthesis in Aspergillus flavus

Konstantinos Grintzalis et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2014)

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Article Chemistry, Applied

Two-step method for encapsulation of oregano essential oil in chitosan nanoparticles: Preparation, characterization and in vitro release study

Seyed Fakhreddin Hosseini et al.

CARBOHYDRATE POLYMERS (2013)

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Article Biotechnology & Applied Microbiology

Assessing essential oil components as plant-based preservatives against fungi that deteriorate herbal raw materials

Prashant Kumar Mishra et al.

INTERNATIONAL BIODETERIORATION & BIODEGRADATION (2013)

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Review Oncology

Population attributable risk of aflatoxin-related liver cancer: Systematic review and meta-analysis

Yan Liu et al.

EUROPEAN JOURNAL OF CANCER (2012)

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Article Chemistry, Applied

The control of Aspergillus flavus with Cinnamomum jensenianum Hand-Mazz essential oil and its potential use as a food preservative

Jun Tian et al.

FOOD CHEMISTRY (2012)

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Article Food Science & Technology

Assessment of some essential oils as food preservatives based on antifungal, antiaflatoxin, antioxidant activities and in vivo efficacy in food system

Bhanu Prakash et al.

FOOD RESEARCH INTERNATIONAL (2012)

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Article Biotechnology & Applied Microbiology

EFFICACY OF ESSENTIAL OIL COMBINATION OF CURCUMA LONGA L. AND ZINGIBER OFFICINALE ROSC. AS A POSTHARVEST FUNGITOXICANT, AFLATOXIN INHIBITOR AND ANTIOXIDANT AGENT

Bhanu Prakash et al.

JOURNAL OF FOOD SAFETY (2012)

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Article Food Science & Technology

Hydrodistillation of Essential Oil from Cymbopogon flexuosus

Jigisha K. Parikh et al.

INTERNATIONAL JOURNAL OF FOOD ENGINEERING (2011)

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Article Environmental Sciences

Global Burden of Aflatoxin-Induced Hepatocellular Carcinoma: A Risk Assessment

Yan Liu et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2010)

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Article Food Science & Technology

Efficacy of chemically characterized Piper betle L. essential oil against fungal and aflatoxin contamination of some edible commodities and its antioxidant activity

Bhanu Prakash et al.

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2010)

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Article Biochemistry & Molecular Biology

Antifungal Activity of the Essential Oil of Illicium verum Fruit and Its Main Component trans-Anethole

Yongfu Huang et al.

MOLECULES (2010)

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Article Biochemical Research Methods

Application of Biolog FF MicroPlate for substrate utilization and metabolite profiling of closely related fungi

Maya Prakash Singh

JOURNAL OF MICROBIOLOGICAL METHODS (2009)

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Article Ecology

Fungal contamination of raw materials of some herbal drugs and recommendation of Cinnamomum camphora oil as herbal fungitoxicant

Priyanka Singh et al.

MICROBIAL ECOLOGY (2008)

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Article Microbiology

Effects of Cymbopogon citratus L. essential oil on the growth, morphogenesis and aflatoxin production of Aspergillus flavus ML2-strain

G. A. Hellal et al.

JOURNAL OF BASIC MICROBIOLOGY (2007)

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Review Food Science & Technology

Essential oils: their antibacterial properties and potential applications in foods - a review

S Burt

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2004)

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Article Agriculture, Multidisciplinary

OM emulsification for the self-aggregation and nanoparticle formation of linoleic acid-modified chitosan in the aqueous system

XG Chen et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2003)

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Article Agriculture, Multidisciplinary

Antioxidant activity and phenolic compounds in selected herbs

W Zheng et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2001)

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Synthesis, characterization, and assessment of chitosan-nanomatrix enriched with antifungal formulation against biodeterioration of active ingredients of selected herbal raw materials

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