Assessment of antimicrobial activity of chitosan/silver nanoparticles hydrogel and cryogel microspheres

This research investigates the synthesis and characterization of hydrogel and cryogel microspheres that are doped with green synthesised silver nanoparticles (CS-AgNPs). Also, the study assesses the antibacterial activity of hydrogel and cryogel microspheres by comparing them with commercial antibiotics. The porous structure of CS and the adequate dispersion of AgNPs were confirmed by SEM and EDX techniques, respectively. The disk diffusion method and the optical density measurement (OD600) confirm the outstanding antimicrobial activity of CS-AgNPs hydrogel and cryogel microspheres in comparison to antibiotics for both Gram-positive and Gram-negative bacteria. The CS-AgNPs microspheres demonstrate promising antimicrobial and biocompatible agents for medical field applications.

Automated summary

This study focuses on synthesizing and characterizing hydrogel and cryogel microspheres doped with green synthesized silver nanoparticles (CS-AgNPs). The antimicrobial activity of these microspheres is compared with commercial antibiotics. SEM and EDX techniques confirm the porous structure of CS and the dispersion of AgNPs, respectively. The results show that CS-AgNPs microspheres exhibit superior antimicrobial activity to antibiotics against both Gram-positive and Gram-negative bacteria. CS-AgNPs microspheres are promising as antimicrobial and biocompatible agents for medical applications.