Safety and immunogenicity of the ChAdOx1, MVA-MERS-S, and GLS-5300 DNA MERS-CoV vaccines

Article Medicine, General & Internal

Homologous and Heterologous Covid-19 Booster Vaccinations

R. L. Atmar et al.

Summary: This study investigated the efficacy of homologous and heterologous booster vaccines in adults who had completed a primary Covid-19 vaccine regimen. The results showed that both types of booster vaccines were safe and immunogenic.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Review Public, Environmental & Occupational Health

Safety, Immunogenicity, and Efficacy of COVID-19 Vaccines in Adolescents, Children, and Infants: A Systematic Review and Meta-Analysis

Yuxuan Du et al.

Summary: The safety, immunogenicity, and efficacy of COVID-19 vaccines in the population aged 0-17 years are acceptable. More research is needed, especially in children under 3 years of age.

FRONTIERS IN PUBLIC HEALTH (2022)

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Article Multidisciplinary Sciences

Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome

Anahita Fathi et al.

Summary: A booster vaccination with MVA-MERS-S is safe and significantly improves immunity to the Middle East Respiratory Syndrome coronavirus.

NATURE COMMUNICATIONS (2022)

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Review Biotechnology & Applied Microbiology

Seroconversion rate after COVID-19 vaccination in patients with solid cancer: A systematic review and meta-analysis

Juntao Yin et al.

Summary: Compared with healthy individuals, COVID-19 vaccines demonstrate favorable immunogenicity and efficacy in patients with solid cancer. The second dose is associated with significantly improved seroconversion, although it is slightly lower in patients with solid cancer compared with healthy individuals.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2022)

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Article Immunology

Immunogenicity of High-Dose MVA-Based MERS Vaccine Candidate in Mice and Camels

Naif Khalaf Alharbi et al.

Summary: This study reported the immunogenicity of high-dose MVA-MERS vaccine in mice and camels. The results showed that MVA-MERS vaccine induced strong antibody responses, including neutralizing antibodies, in both mice and camels. These findings contribute to the further development and evaluation of this vaccine as a potential approach to reduce MERS-CoV transmission.

VACCINES (2022)

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Letter Medicine, General & Internal

BNT162b2 Vaccine Booster and Covid-19 Mortality

Thomas Rohban

Summary: In a real-world data analysis, researchers found that adults aged 50 or above who received a booster shot of the Pfizer-BioNTech vaccine at least 5 months after their second dose had 90% lower mortality due to Covid-19 compared to those who did not receive a booster. The study suggests that reports on all-cause mortality would have been helpful in improving our understanding of the booster effect.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Letter Medicine, General & Internal