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Mixed Germ Cell Tumor with a Yolk Sac Tumor Component in the Medulla Oblongata of a 50-year-old Patient: A Case Report and Literature Review

期刊

INTERNAL MEDICINE
卷 62, 期 6, 页码 915-921

出版社

JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.9447-22

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germ cell tumor; yolk sac tumor; medulla oblongata

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Yolk sac tumor (YST) is a rare brain tumor that mainly affects patients under 30 years old, with the most common sites being the pineal and suprasellar regions. YSTs in the medulla oblongata are extremely rare and can be difficult to diagnose due to their uncommon growth patterns. They have a poor prognosis, but this case study presents a 50-year-old woman who remained tumor-free during an 18-month follow-up.
Yolk sac tumor (YST) is a rare primary brain tumor that occurs almost exclusively in patients under 30 years old. Intracranial germ cell tumors are most frequently located in the pineal and suprasellar region. Me-dulla oblongata YSTs are particularly rare. Extragonadal YSTs may be difficult to diagnose because of their characteristics, such as the rarity and variety of growth patterns. Furthermore, they are known to have a very poor prognosis. We herein report a case of YST of the medulla oblongata in a 50-year-old woman. She was followed up for 18 months without any tumor recurrence.

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