期刊
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
卷 14, 期 1, 页码 177-187出版社
SPRINGER
DOI: 10.1007/s13738-016-0968-x
关键词
Domino Knoevenagel hetero-Diels-Alder; Pyranoquinolinones; 1,3-Dicarbonyls
资金
- University of Tehran
An efficient catalyst-free synthesis of novel annulated hybrid derivatives of two known scaffolds, dihydroquinolinone and pyranopyranone, pyranopyrimidinedione, pyranocoumarin or chromenone is described. N-(2-Formylphenyl)-N-methylcinnamamides underwent a one-pot domino Knoevenagel hetero-Diels-Alder reaction with dimedone, N,N-dimethylbarbituric acid, 1,3-indanedione, 4-hydroxycoumarins and 4-hydroxy-6-methyl-2H-pyran-2-one in water, affording the desired tetra and pentacyclic pyranoquinolinones in excellent yields.
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