☆ 4.8 Article

Antiviral therapy substantially reduces HCC risk in patients with chronic hepatitis B infection in the indeterminate phase

HEPATOLOGY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Gastroenterology & Hepatology

Liver Complications in Untreated Treatment-Ineligible versus Treated Treatment-Eligible Patients with Hepatitis B

Daniel Q. Huang et al.

Summary: The aim of this study was to determine whether current practice guidelines adequately identify CHB patients who will benefit from antiviral therapy. Through a retrospective cohort study, we found that patients who do not meet treatment criteria have twice the risk of developing cirrhosis and hepatocellular carcinoma compared to patients who are eligible and treated.

DIGESTIVE DISEASES (2023)

添加到收藏夹

Article Gastroenterology & Hepatology

Global burden of liver cancer in males and females: Changing etiological basis and the growing contribution of NASH

Darren Jun Hao Tan et al.

Summary: This study estimated sex differences in the burden of liver cancer globally and found that males have a higher burden. However, the incidence and death rates of NASH-associated liver cancer in females approach that of males.

HEPATOLOGY (2023)

添加到收藏夹

Article Gastroenterology & Hepatology

Natural History and Hepatocellular Carcinoma Risk in Untreated Chronic Hepatitis B Patients With Indeterminate Phase

Daniel Q. Huang et al.

Summary: This study found that a significant proportion of patients with chronic hepatitis B are in the indeterminate phase. Of these patients, around half remain indeterminate and one-fifth transition to the immune active phase. The risk of hepatocellular carcinoma is significantly higher in persistently indeterminate CHB patients, particularly in those aged 45 years and older.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Treatment Algorithm for Managing Chronic Hepatitis B Virus Infection in the United States: 2021 Update

Paul Martin et al.

Summary: This study introduces the latest management algorithm for chronic hepatitis B (CHB). The algorithm aims to assist physicians in managing CHB while new antiviral strategies are being developed. The recommendations are based on scientific literature, clinical experience, and expert consensus, and the study identifies areas of continued debate and research needs.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2022)

添加到收藏夹

Article Cell Biology

Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer

Daniel Q. Huang et al.

Summary: Liver cancer epidemiology is changing due to factors such as increasing alcohol consumption, rising obesity rates, and advancements in hepatitis B and C treatment. The Global Burden of Disease study estimated global and regional trends in liver cancer burden, revealing a 25% increase in liver cancer deaths between 2010 and 2019. Non-alcoholic steatohepatitis (NASH) and alcohol were found to have the fastest growing death rates, while hepatitis B and C showed declines. Urgent measures are needed globally to address metabolic risk factors and slow the growing burden of NASH-associated liver cancer, particularly in the Americas.

CELL METABOLISM (2022)

添加到收藏夹

Article Medicine, General & Internal

Risk of Hepatocellular Carcinoma With Tenofovir vs Entecavir Treatment for Chronic Hepatitis B Virus A Reconstructed Individual Patient Data Meta-analysis

Darren Jun Hao Tan et al.

Summary: This study conducted a reconstructed individual patient data meta-analysis to provide robust estimates for the comparative hepatocellular carcinoma (HCC) risk between patients receiving tenofovir or entecavir. The results showed that tenofovir was associated with decreased HCC incidence compared with entecavir. However, there was no significant difference in the analysis of clinical cohort studies. The mean time to HCC development was slightly longer for patients receiving tenofovir compared to those receiving entecavir in administrative database studies.

JAMA NETWORK OPEN (2022)

添加到收藏夹

Review Gastroenterology & Hepatology

Should Treatment Indications for Chronic Hepatitis B Be Expanded?

Wen-Juei Jeng et al.

Summary: Current treatment for chronic hepatitis B virus (HBV) does not eradicate the virus, requiring long-term maintenance for most patients. Expanding treatment to certain patient populations, such as immune tolerant patients and those with evidence of liver disease, is supported by available evidence. However, data supporting treatment expansion for confirmed inactive carriers and other immune tolerant patients is lacking. New therapies that can achieve HBsAg loss in a high percentage of patients after a finite course of treatment may allow for more liberal HBV treatment indications in the future.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

添加到收藏夹

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

添加到收藏夹

Review Gastroenterology & Hepatology

Estimating the proportion of people with chronic hepatitis B virus infection eligible for hepatitis B antiviral treatment worldwide: a systematic review and meta-analysis

Mingjuan Tan et al.

Summary: Many people with chronic HBV infection worldwide may be eligible for treatment, but the proportion of those who are actually eligible is not high. Future studies should focus more on reporting treatment eligibility in order to improve global treatment coverage.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis-2021 update

Annalisa Berzigotti et al.

Summary: The article provides the latest update to the EASL Clinical Practice Guidelines on the use of non-invasive tests for assessing liver disease severity and prognosis, with a focus on topics with relevant evidence published in the last 5 years.

JOURNAL OF HEPATOLOGY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

Chronic Hepatitis B Prevalence Among Foreign-Born and US-Born Adults in the United States, 1999-2016

Michael H. Le et al.

HEPATOLOGY (2020)

添加到收藏夹

Article Immunology

Real-World Effectiveness From the Asia Pacific Rim Liver Consortium for HBV Risk Score for the Prediction of Hepatocellular Carcinoma in Chronic Hepatitis B Patients Treated With Oral Antiviral Therapy

Hwai- Yang et al.

JOURNAL OF INFECTIOUS DISEASES (2020)

添加到收藏夹

Review Microbiology

Hepatitis B Virus: Advances in Prevention, Diagnosis, and Therapy

Mindie H. Nguyen et al.

CLINICAL MICROBIOLOGY REVIEWS (2020)

添加到收藏夹

Review Gastroenterology & Hepatology

Hepatitis B: Who to treat? A critical review of international guidelines

Daniel Q. Huang et al.

LIVER INTERNATIONAL (2020)

添加到收藏夹

Article Medicine, General & Internal

Diagnosis Rates of Chronic Hepatitis B in Privately Insured Patients in the United States

Eiichi Ogawa et al.

JAMA NETWORK OPEN (2020)

添加到收藏夹

Article Immunology

Reduced Incidence of Hepatocellular Carcinoma in Cirrhotic and Noncirrhotic Patients With Chronic Hepatitis B Treated With Tenofovir-A Propensity Score-Matched Study

Mindie H. Nguyen et al.

JOURNAL OF INFECTIOUS DISEASES (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

The risk of hepatocellular carcinoma among chronic hepatitis B virus-infected patients outside current treatment criteria

Dong Hyun Sinn et al.

JOURNAL OF VIRAL HEPATITIS (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

Poor Adherence to Guidelines for Treatment of Chronic Hepatitis B Virus Infection at Primary Care and Referral Practices

Vy H. Nguyen et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases

Jorge A. Marrero et al.

HEPATOLOGY (2018)

添加到收藏夹

Article Gastroenterology & Hepatology

Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance

Norah A. Terrault et al.

HEPATOLOGY (2018)

添加到收藏夹

Article Gastroenterology & Hepatology

EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection

JOURNAL OF HEPATOLOGY (2017)

添加到收藏夹

Review Multidisciplinary Sciences

Comparison of diagnostic accuracy of magnetic resonance elastography and Fibroscan for detecting liver fibrosis in chronic hepatitis B patients: A systematic review and meta-analysis

Huanming Xiao et al.

PLOS ONE (2017)

添加到收藏夹

Article Gastroenterology & Hepatology

AASLD guidelines for treatment of chronic hepatitis B

Norah A. Terrault et al.

HEPATOLOGY (2016)

添加到收藏夹

Article Gastroenterology & Hepatology

Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update

S. K. Sarin et al.

HEPATOLOGY INTERNATIONAL (2016)

添加到收藏夹

Article Medicine, General & Internal

Lower liver cancer risk with antiviral therapy in chronic hepatitis B patients with normal to minimally elevated ALT and no cirrhosis

Joseph K. Hoang et al.

MEDICINE (2016)

添加到收藏夹

Article Gastroenterology & Hepatology

Association of Nucleos(t)ide Analogue Therapy With Reduced Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B-A Nationwide Cohort Study

Chun-Ying Wu et al.

GASTROENTEROLOGY (2014)

添加到收藏夹

Article Gastroenterology & Hepatology

Entecavir Treatment Reduces Hepatic Events and Deaths in Chronic Hepatitis B Patients With Liver Cirrhosis

Grace Lai-Hung Wong et al.

HEPATOLOGY (2013)

添加到收藏夹

Article Gastroenterology & Hepatology

Long-Term Entecavir Treatment Reduces Hepatocellular Carcinoma Incidence in Patients With Hepatitis B Virus Infection

Tetsuya Hosaka et al.

HEPATOLOGY (2013)

添加到收藏夹

Article Gastroenterology & Hepatology

Meta-analysis: treatment of hepatitis B infection reduces risk of hepatocellular carcinoma

J. J. Y. Sung et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2008)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.