A multisociety Delphi consensus statement on new fatty liver disease nomenclature

Article Gastroenterology & Hepatology

AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease

Mary E. Rinella et al.

HEPATOLOGY (2023)

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Review Medicine, General & Internal

The EASL-Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality

Tom H. Karlsen et al.

LANCET (2022)

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Editorial Material Gastroenterology & Hepatology

Expert Panel Review to Compare FDA and EMA Guidance on Drug Development and Endpoints in Nonalcoholic Steatohepatitis

Rohit Loomba et al.

GASTROENTEROLOGY (2022)

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Article Gastroenterology & Hepatology

Knowledge of liver fibrosis stage among adults with NAFLD/NASH improves adherence to lifestyle changes

Patrizia Carrieri et al.

Summary: This study found that unawareness about fibrosis stage and poor adherence to lifestyle adjustments are common among individuals with NAFLD/NASH. It also identified a higher risk of unawareness and poor adherence among those with obesity. Improving patient-provider communication and implementing educational programs may help address these issues.

LIVER INTERNATIONAL (2022)

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Article Gastroenterology & Hepatology

From NAFLD to MAFLD: Implications of a Premature Change in Terminology

Zobair M. Younossi et al.

Summary: The article discusses the proposal to rename NAFLD to MAFLD, highlighting the shortcomings of the new term and warning that changing the name without a comprehensive understanding may have negative implications for the field. The recommendation is to establish a true international consensus group to assess the impact and consequences of the terminology change and make recommendations based on available evidence to move the field forward.

HEPATOLOGY (2021)

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Letter Gastroenterology & Hepatology

Dual aetiology fatty liver disease: A recently proposed term associated with potential pitfalls

Christophe Moreno et al.

JOURNAL OF HEPATOLOGY (2021)

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Article Gastroenterology & Hepatology

Assessment of hepatic steatosis by controlled attenuation parameter using the M and XL probes: an individual patient data meta-analysis

David Petroff et al.

Summary: This study conducted an individual patient data meta-analysis to evaluate the diagnostic properties of hepatic steatosis using CAP. Results showed that optimal cutoffs for CAP varied according to different etiologies of liver disease. While CAP may not adequately grade steatosis in patients with NAFLD, it can effectively identify significant steatosis in patients with viral hepatitis.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2021)

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Review Gastroenterology & Hepatology

Diagnosis and management of secondary causes of steatohepatitis

Roman Liebe et al.

Summary: The term NAFLD was originally used to describe hepatic fat deposition in association with the metabolic syndrome. Secondary causes of fatty liver disease should be considered during diagnosis and treatment to halt disease progression, while genetic variants may play a role in the development and progression of liver diseases.

JOURNAL OF HEPATOLOGY (2021)

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Article Gastroenterology & Hepatology

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis-2021 update

Annalisa Berzigotti et al.

Summary: The article provides the latest update to the EASL Clinical Practice Guidelines on the use of non-invasive tests for assessing liver disease severity and prognosis, with a focus on topics with relevant evidence published in the last 5 years.

JOURNAL OF HEPATOLOGY (2021)

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Article Multidisciplinary Sciences

Preparing, conducting, and analyzing Delphi surveys: Cross-disciplinary practices, new directions, and advancements

Daniel Beiderbeck et al.

Summary: The Delphi method is a scientific approach to organizing and structuring expert discussions to generate insights on controversial topics with limited information. Its publication frequency has been increasing in various disciplines, especially in recent decades. With the rising uncertainty caused by rapid technological and social change globally, collective expert opinions and assessments are likely to become more valuable.

METHODSX (2021)

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Article Gastroenterology & Hepatology