Subannular repair for secondary mitral regurgitation: a step towards peaceful conversations

Article Cardiac & Cardiovascular Systems

Subannular repair in secondary mitral regurgitation with restricted leaflet motion during systole

Jonas Pausch et al.

Summary: This study evaluated the safety and efficacy of standardised subannular repair for treating ventricular secondary mitral regurgitation (Carpentier type IIIb) through a 1-year follow-up. The results showed that subannular repair successfully reduced mitral leaflet tethering, leading to improved survival, cardiac function, and a reduced rate of mitral regurgitation.

HEART (2023)

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Article Medicine, General & Internal

Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation

Gregg W. Stone et al.

Summary: Data from a 5-year follow-up of outcomes after transcatheter edge-to-edge repair of severe mitral regurgitation in patients with heart failure demonstrate that this procedure, in addition to medical therapy, leads to lower rates of hospitalization for heart failure and all-cause mortality compared to medical therapy alone.

NEW ENGLAND JOURNAL OF MEDICINE (2023)

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Article Cardiac & Cardiovascular Systems

Clinical impact of changes in mitral regurgitation severity after medical therapy optimization in heart failure

Matteo Pagnesi et al.

Summary: This study evaluated the evolution and impact of mitral regurgitation (MR) in heart failure patients after guideline-recommended medical therapy (GRMT). The results showed that ACEi/ARB up-titration and a left ventricular ejection fraction (LVEF) ≥ 50% were associated with MR improvement, while the presence of moderate-severe MR after GRMT was associated with worse outcomes.

CLINICAL RESEARCH IN CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Delayed hospitalisation for heart failure after transcatheter repair or medical treatment for secondary mitral regurgitation: a landmark analysis of the MITRA-FR trial

Guillaume Leurent et al.

Summary: In the 12-month landmark analysis of the MITRA-FR trial, the rate of heart failure hospitalizations between 12 and 24 months was approximately half in patients treated with TMVR on top of GDMT compared to those treated with GDMT alone, but this difference did not reach statistical significance due to a low number of events.

EUROINTERVENTION (2022)

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Article Cardiac & Cardiovascular Systems

Angiotensin Receptor Neprilysin Inhibitor for Functional Mitral Regurgitation PRIME Study

Duk-Hyun Kang et al.

CIRCULATION (2019)

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Article Cardiac & Cardiovascular Systems

Evolution of Functional Mitral Regurgitation and Prognosis in Medically Managed Heart Failure Patients With Reduced Ejection Fraction

Riwa Nasser et al.

JACC-HEART FAILURE (2017)

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Article Medicine, General & Internal

Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation

D. Goldstein et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

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Subannular repair for secondary mitral regurgitation: a step towards peaceful conversations

相关参考文献

Subannular repair in secondary mitral regurgitation with restricted leaflet motion during systole

Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation

Clinical impact of changes in mitral regurgitation severity after medical therapy optimization in heart failure

Delayed hospitalisation for heart failure after transcatheter repair or medical treatment for secondary mitral regurgitation: a landmark analysis of the MITRA-FR trial

Angiotensin Receptor Neprilysin Inhibitor for Functional Mitral Regurgitation PRIME Study

Evolution of Functional Mitral Regurgitation and Prognosis in Medically Managed Heart Failure Patients With Reduced Ejection Fraction

Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation

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