☆ 4.8 Letter

Antibiotic use and inflammatory bowel disease: number needed to harm?

GUT (2023)

Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study

Adam S. Faye et al.

Summary: This study used Danish nationwide registries to investigate the association between antibiotic exposure and the risk of inflammatory bowel disease (IBD). The results showed that antibiotic exposure was associated with an increased risk of IBD, especially in individuals aged 40 years and older. The risk was highest within 1-2 years after antibiotic exposure and with the use of antibiotics targeting gastrointestinal pathogens.

GUT (2023)

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Article Gastroenterology & Hepatology

Trends in Biochemical Parameters, Healthcare Resource and Medication Use in the 5 Years Preceding IBD Diagnosis: A Health Maintenance Organization Cohort Study

Nathaniel A. Cohen et al.

Summary: This retrospective study analyzed changes in healthcare resource utilization, medication use, and laboratory results in the years before diagnosis in patients with inflammatory bowel disease (IBD). The findings suggest that there are significant changes in laboratory parameters, healthcare resource utilization, and medication use during the 5-year period preceding IBD diagnosis.

DIGESTIVE DISEASES AND SCIENCES (2023)

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Article Gastroenterology & Hepatology