4.7 Article

STAT5A modulates gastric cancer progression via upregulation of CD44

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Circular RNA circPPP6R3 upregulates CD44 to promote the progression of clear cell renal cell carcinoma via sponging miR-1238-3p

Zhiliang Chen et al.

Summary: circPPP6R3 is a highly expressed circular RNA in clear cell renal cell carcinoma (ccRCC), and it is associated with the severity and progression of the disease. It interacts with miR-1238-3p and upregulates the expression of CD44, promoting cancer cell proliferation and metastasis. This study provides new insights into biomarkers and potential therapeutic approaches for ccRCC.

CELL DEATH & DISEASE (2022)

Article Oncology

Loss of STAT5A promotes glucose metabolism and tumor growth through miRNA-23a-AKT signaling in hepatocellular carcinoma

Yabo Jiang et al.

Summary: The study identified that increased expression of miR-23a in HCC tissues is associated with worse survival, and miR-23a negatively regulates STAT5A to activate AKT signaling, leading to accelerated tumor growth. This indicates that the miR-23a-STAT5A-AKT signaling pathway plays a critical role in altering glucose metabolism in HCC and may provide new opportunities for effective therapy.

MOLECULAR ONCOLOGY (2021)

Article Gastroenterology & Hepatology

Global Burden of 5 Major Types of Gastrointestinal Cancer

Melina Arnold et al.

GASTROENTEROLOGY (2020)

Article Biochemistry & Molecular Biology

Expression of DEC2 enhances chemosensitivity by inhibiting STAT5A in gastric cancer

Hongyu Li et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2019)

Review Oncology

The biology and role of CD44 in cancer progression: therapeutic implications

Chen Chen et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)

Review Oncology

Stem cell fate in cancer growth, progression and therapy resistance

Nikki K. Lytle et al.

NATURE REVIEWS CANCER (2018)

Article Biochemistry & Molecular Biology

Resistance to HSP90 inhibition involving loss of MCL1 addiction

S. Busacca et al.

ONCOGENE (2016)

Article Biochemistry & Molecular Biology

CD44: More than a mere stem cell marker

I. Morath et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2016)

Article Cell & Tissue Engineering

Different Levels of Twist1 Regulate Skin Tumor Initiation, Stemness, and Progression

Benjamin Beck et al.

CELL STEM CELL (2015)

Article Cell & Tissue Engineering

Concise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic Target

Yongmin Yan et al.

STEM CELLS TRANSLATIONAL MEDICINE (2015)

Review Biotechnology & Applied Microbiology

Therapeutic modulators of STAT signalling for human diseases

Gabriella Miklossy et al.

NATURE REVIEWS DRUG DISCOVERY (2013)

Article Oncology

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

Xiaoxian Li et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2008)