Production of iron-peptide complexes from spent yeast for nutraceutical industry

Iron (Fe) deficiencies are a major health condition concern and over the years many so-lutions in the form of Fe supplementation have been investigated. Organic Fe-complexes are the most promising for Fe deficiencies remediation. The aim of present study was to value peptide rich waste streams from & beta;-glucan and mannan production from spent yeast (Gpep and Mpep, respectively) as Fe-peptide complexes for Fe supplementation. These waste streams were first subjected to ultrafiltration treatment before assessing the ca-pacity of these fractions to complex Fe was evaluated, without, and with nitrogen. Results have shown that Gpep > 1 kDa was the best fraction with a optimal pH of 6.0 and a time of 30 min. The resulting Fe-peptide complex was characterized using powder XDR, fluores-cence, FTIR, SEM and Mastersizer Laser Diffraction. Results have shown that Gpep and Mpep waste streams have potential application as Fe supplementation in the form of Fe peptide complexes.& COPY; 2023 The Author(s). Published by Elsevier Ltd on behalf of Institution of Chemical Engineers. This is an open access article under the CC BY license (http://creative-commons.org/licenses/by/4.0/).

Automated summary

This study focused on evaluating the potential of peptide-rich waste streams from β-glucan and mannan production from spent yeast as iron-peptide complexes for iron supplementation. The waste streams were treated with ultrafiltration and their ability to complex iron was assessed. The results showed that Gpep > 1 kDa fraction had the best capacity for iron complexation at pH 6.0 and a time of 30 min. The iron-peptide complex was characterized using various techniques. The results suggest that Gpep and Mpep waste streams have potential as iron supplementation in the form of iron-peptide complexes.