相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin
Ashley J. Russo et al.
NATURE IMMUNOLOGY (2021)
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation
Zhiya Deng et al.
CELL DEATH & DISEASE (2021)
Melatonin Ameliorates LPS-Induced Testicular Nitro-oxidative Stress (iNOS/TNFα) and Inflammation (NF-kB/COX-2) via Modulation of SIRT-1
Jitendra Kumar et al.
REPRODUCTIVE SCIENCES (2021)
Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway
Yue Li et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)
D-mannose suppresses macrophage IL-1β production
Simone Torretta et al.
NATURE COMMUNICATIONS (2020)
Minocycline promotes cardiomyocyte mitochondrial autophagy and cardiomyocyte autophagy to prevent sepsis-induced cardiac dysfunction by Akt/mTOR signaling
Erfei Zhang et al.
APOPTOSIS (2019)
circ-Sirt1 controls NF-B activation via sequence-specific interaction and enhancement of SIRT1 expression by binding to miR-132/212 in vascular smooth muscle cells
Peng Kong et al.
NUCLEIC ACIDS RESEARCH (2019)
Connexin-43-dependent ATP release mediates macrophage activation during sepsis
Michel Dosch et al.
ELIFE (2019)
Reduction of SIRT1 blunts the protective effects of ischemic post-conditioning in diabetic mice by impairing the Akt signaling pathway
Mingge Ding et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)
Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis
MacRae F. Linton et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
EP300 and SIRT1/6 Co-Regulate Lapatinib Sensitivity Via Modulating FOXO3-Acetylation and Activity in Breast Cancer
Zimam Mahmud et al.
CANCERS (2019)
Distinct functions of AKT isoforms in breast cancer: a comprehensive review
Nico Hinz et al.
CELL COMMUNICATION AND SIGNALING (2019)
Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming
Agnes L. C. Ong et al.
AGEING RESEARCH REVIEWS (2018)
The PI3K/AKT signaling pathway in regulatory T-cell development, stability, and function
Saige L. Pompura et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2018)
Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer
Nikos Koundouros et al.
FRONTIERS IN ONCOLOGY (2018)
Sirtuins and Immuno-Metabolism of Sepsis
Xianfeng Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Immunoadjuvant therapy in sepsis: novel strategies for immunosuppressive sepsis coming down the pike
Eizo Watanabe et al.
ACUTE MEDICINE & SURGERY (2018)
Current therapies and targets for type 2 diabetes mellitus
Dinesh K. Chellappan et al.
PANMINERVA MEDICA (2018)
Histone acetyltransferase p300/CBP inhibitor C646 blocks the survival and invasion pathways of gastric cancer cell lines
Ya-Mei Wang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
The critical role of Akt in cardiovascular function
Prasanna Abeyrathna et al.
VASCULAR PHARMACOLOGY (2015)
The N-Terminal Domain of SIRT1 Is a Positive Regulator of Endogenous SIRT1-Dependent Deacetylation and Transcriptional Outputs
Fiorella Ghisays et al.
CELL REPORTS (2015)
SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia
Daniel Sasca et al.
BLOOD (2014)
Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways
Dexi Zhou et al.
CELLULAR SIGNALLING (2014)
Regulation of Akt Signaling by Sirtuins Its Implication in Cardiac Hypertrophy and Aging
Vinodkumar B. Pillai et al.
CIRCULATION RESEARCH (2014)
Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65
Shohei Shinozaki et al.
SCIENCE SIGNALING (2014)
Posttranslational regulation of Akt in human cancer
Chia-Hsin Chan et al.
CELL AND BIOSCIENCE (2014)
Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders
Anu Kauppinen et al.
CELLULAR SIGNALLING (2013)
An overview of the crosstalk between inflammatory processes and metabolic dysregulation during diabetic cardiomyopathy
Xavier Palomer et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)
Severe Sepsis and Septic Shock REPLY
Derek C. Angus et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
The ways and means that fine tune Sirt1 activity
Javier R. Revollo et al.
TRENDS IN BIOCHEMICAL SCIENCES (2013)
The inflammatory response in sepsis
Markus Bosmann et al.
TRENDS IN IMMUNOLOGY (2013)
Severe Sepsis and Septic Shock
Derek C. Angus et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Macrophage plasticity and polarization: in vivo veritas
Antonio Sica et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
Alicia Arranz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Akt signalling in health and disease
Ingeborg Hers et al.
CELLULAR SIGNALLING (2011)
The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy
Nagalingam R. Sundaresan et al.
SCIENCE SIGNALING (2011)
Protective and pathogenic functions of macrophage subsets
Peter J. Murray et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Regulation of Akt signaling activation by ubiquitination
Wei-Lei Yang et al.
CELL CYCLE (2010)
Posttranslational modifications of NF-kappa B: Another layer of regulation for NF-kappa B signaling pathway
Bo Huang et al.
CELLULAR SIGNALLING (2010)
Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-α production in cultured macrophage cell lines
Zheng Shen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
Jesse J. Smith et al.
BMC SYSTEMS BIOLOGY (2009)
Gene-specific control of the TLR-induced inflammatory response
Simmie L. Foster et al.
CLINICAL IMMUNOLOGY (2009)
The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs
Ariadne Androulidaki et al.
IMMUNITY (2009)
The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation
Wei-Lei Yang et al.
SCIENCE (2009)
Exploring the full spectrum of macrophage activation
David M. Mosser et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B
MP Scheid et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
High-resolution structure of the pleckstrin homology domain of protein kinase B/Akt bound to phosphatidylinositol (3,4,5)-trisphosphate
CC Thomas et al.
CURRENT BIOLOGY (2002)