☆ 4.6 Review

European Association of Urology-American Society of Clinical Oncology Collaborative Guideline on Penile Cancer: 2023 Update

EUROPEAN UROLOGY (2023)

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Review Dermatology

The management of penile intraepithelial neoplasia (PeIN): clinical and histological features and treatment of 345 patients and a review of the literature

G. Kravvas et al.

Summary: This study describes the clinical and histological characteristics, treatments, and outcomes of 345 patients with PeIN. The majority of patients had PeIN alone, with a small percentage progressing to PSCC. HPV and lichen sclerosus were common associated factors. Most patients required surgical intervention, while topical treatments showed limited efficacy.

JOURNAL OF DERMATOLOGICAL TREATMENT (2022)

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Article Andrology

Neoadjuvant chemotherapy for patients with locally advanced penile cancer: an updated evidence

Xian-Yan-Ling Yi et al.

Summary: This study synthesized 14 published studies and found that patients with locally advanced penile cancer who achieved an objective response to neoadjuvant chemotherapy (NAC) had better survival outcomes. The taxane-platinum (TP) regimen group performed better than the nontaxane-platinum (NTP) regimen group, but had more frequent toxicity. Further studies are needed to confirm these findings.

ASIAN JOURNAL OF ANDROLOGY (2022)

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Article Urology & Nephrology

High diagnostic accuracy of inguinal ultrasonography and fine-needle aspiration followed by dynamic sentinel lymph node biopsy in men with impalpable and palpable inguinal lymph nodes

Esther W. C. Lee et al.

Summary: Inguinal ultrasound and fine-needle aspiration followed by dynamic sentinel lymph node biopsy (DSNB) can accurately stage patients with both impalpable and palpable inguinal lymph nodes, providing logistical and surgical advantages.

BJU INTERNATIONAL (2022)

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Article Urology & Nephrology

Incidence of penile intraepithelial neoplasia and treatment strategies in Sweden 2000-2019

Sinja Kristiansen et al.

Summary: The incidence of penile intraepithelial neoplasia (PeIN) in Sweden has doubled over a period of 20 years. Complications were three times more common in laser surgery compared to local surgery. There has been an increase in the use of local surgery and treatment with imiquimod and topical 5-fluorouracil (5-FU) over time.

BJU INTERNATIONAL (2022)

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Article Urology & Nephrology

Clinicopathological predictors of finding additional inguinal lymph node metastases in penile cancer patients after positive dynamic sentinel node biopsy: a European multicentre evaluation

Hielke M. de Vries et al.

Summary: This study aimed to develop a predictive model using DSNB characteristics to identify penile cancer patients in whom inguinal lymph node dissection (ILND) can be omitted. The study found that a small but clinically important group of patients still had additional lymph node metastases (LNM) after ILND. However, the DSNB characteristics did not improve the accuracy of selecting which lymph nodes can be omitted from ILND. Therefore, completion ILND is still necessary for all patients with positive DSNB.

BJU INTERNATIONAL (2022)

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Meeting Abstract Oncology

Clinical results of PERICLES: A phase II trial investigating atezolizumab plus /- radiotherapy for advanced squamous cell carcinoma of the penis.

Hielke Martijn de Vries et al.

JOURNAL OF CLINICAL ONCOLOGY (2022)

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Article Multidisciplinary Sciences

Comparison of different surgical methods and strategies for inguinal lymph node dissection in patients with penile cancer

Yanxiang Shao et al.

Summary: This study compared the clinical feasibility and oncological outcome of different surgical techniques for inguinal lymphadenectomy (ILND) in patients with penile cancer. The results showed that laparoscopic ILND had a shorter hospital stay and lower wound healing delay rate compared to open surgery. However, laparoscopic ILND had a longer drainage time. There were no significant differences in intraoperative parameters, complications, and survival between the two groups. Saphenous vein preservation had limited value in reducing complications. Delayed lymphadenectomy may be a more reasonable option for ILND.

SCIENTIFIC REPORTS (2022)

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Review Urology & Nephrology

Treatment Options and Outcomes for Men with Penile Intraepithelial Neoplasia: A Systematic Review

Allaudin Issa et al.

Summary: Penile intraepithelial neoplasia (PeIN) is a rare skin condition that has the potential to progress to invasive penile cancer. Treatment options include topical agents and surgical treatments, with varying response rates and recurrence rates. Surgery has lower recurrence rates, but topical agents may have side effects.

EUROPEAN UROLOGY FOCUS (2022)

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Article Urology & Nephrology

Incidence and risk factor analysis of complications after sentinel node biopsy for penile cancer

Lieke Wever et al.

Summary: The study aims to determine the incidence and types of complications after dynamic sentinel node biopsy (DSNB) in patients with penile cancer (PeCa) and identify risk factors for postoperative complications. The results showed that DSNB is associated with a considerable risk of postoperative mild-to-moderate complications, and the probability of complications increases with the number of removed lymph nodes.

BJU INTERNATIONAL (2022)

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Article Urology & Nephrology

Patterns of recurrence in penile cancer: Implications for surveillance strategies

A. Arora et al.

EUROPEAN UROLOGY (2022)

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Article Oncology

Lymphovascular and perineural invasion are risk factors for inguinal lymph node metastases in men with T1G2 penile cancer

Christian D. Fankhauser et al.

Summary: The purpose of this study was to analyze the risk of inguinal lymph node (ILN) metastases in T1G2 penile cancer, stratified by lymphovascular invasion (LVI), perineural invasion (PNI), and tumor size. The results showed that despite being clinically node negative, approximately one out of ten men with T1G2 overall and one out of four men with either LVI + or PNI + still had ILN metastases. Therefore, invasive ILN staging should be strongly recommended in T1G2 patients with LVI + or PNI +, but must be discussed in patients with T1G2 with LVI- or PNI-.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2022)

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Review Oncology

Effectiveness and safety of adjuvant chemotherapy compared to neoadjuvant chemotherapy in patients with penile cancer and positive lymph nodes regarding overall survival and free disease survival: a systematic review and meta-analysis

Juan Fernando Paz Rojas et al.

Summary: The study evaluated the effectiveness of adjuvant chemotherapy compared with neoadjuvant chemotherapy in terms of overall survival and progression-free survival in node-positive penile cancer patients. The results showed no difference in overall survival, but a better response in progression-free survival with adjuvant chemotherapy. More studies with adequate design are needed to provide stronger recommendations.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2022)

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Review Urology & Nephrology

The 2022 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours

Holger Moch et al.

Summary: The fifth edition of the WHO classification of urogenital tumours has made significant revisions, including the introduction of molecular-driven renal tumour classification and simplification of the morphologic classification of penile squamous cell carcinomas. A new chapter has also been added for tumours of the scrotum. The main nomenclature for testicular tumours remains the same, but there have been changes in some terms.

EUROPEAN UROLOGY (2022)

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Review Urology & Nephrology

Immune-based therapies in penile cancer

Vidhu B. Joshi et al.

Summary: Penile cancer is a rare malignancy with limited therapeutic options. Immune-based therapies, including immune-checkpoint blockade, vaccines, and adoptive T cell therapies, have shown potential for treating advanced penile cancer. Various immune cells have been found to infiltrate penile cancer tumors, and immune markers and HPV-status have prognostic value. However, there is limited evidence regarding the safety and efficacy of immune-based therapies in penile cancer, and further research is needed.

NATURE REVIEWS UROLOGY (2022)

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Article Public, Environmental & Occupational Health

Global Pattern and Trends in Penile Cancer Incidence: Population-Based Study

Leiwen Fu et al.

Summary: Penile cancer is on the rise in many countries, particularly in Europe. Measures to lower the risk of penile cancer, such as improving penile hygiene and promoting male human papillomavirus vaccination, may be necessary to reduce the burden of the disease on society.

JMIR PUBLIC HEALTH AND SURVEILLANCE (2022)

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Review Urology & Nephrology

Advances in penile-sparing surgical approaches

Karl H. Pang et al.

Summary: This article reviews the oncological and functional outcomes of penile-preserving surgery (PPS) in the treatment of penile cancer, and introduces different penile-sparing approaches and their outcomes. PPS is now the standard of care in specialist centres for distal tumours not involving the corpus cavernosa.

ASIAN JOURNAL OF UROLOGY (2022)

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Review Urology & Nephrology

What Is the Most Effective Management of the Primary Tumor in Men with Invasive Penile Cancer: A Systematic Review of the Available Treatment Options and Their Outcomes

Vasileios I. Sakalis et al.

Summary: The study assessed the effectiveness of different treatments for penile cancer. The results showed that penile-sparing surgery and amputative surgery had similar recurrence rates, but amputative surgery had a negative impact on sexual function. Penile-sparing surgery and radiotherapy had a higher risk of local recurrence, but preserved sexual function and quality of life better. Laser and Moh's micrographic surgery were suitable for smaller lesions.

EUROPEAN UROLOGY OPEN SCIENCE (2022)

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Article Urology & Nephrology

Saphenous-sparing Ascending Video Endoscopic Inguinal Lymph Node Dissection Using a Leg Approach: Surgical Technique and Perioperative and Pathological Outcomes

Christian D. Fankhauser et al.

Summary: VEILND-AS+ has a longer operation time but a shorter hospital stay compared to oILND, offering a possibly lower risk of skin necrosis and wound breakdown. Further improvements in the VEILND-AS+ technique are required to reduce complications associated with dead space and injury to lymphatic vessels.

EUROPEAN UROLOGY OPEN SCIENCE (2022)

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Article Urology & Nephrology

Human Papilloma Virus (HPV) status may impact treatment outcomes in patients with pre-cancerous penile lesions (an eUROGEN Study)

Sophie Ashley et al.

Summary: Penile intra-epithelial neoplasia (PeIN) is a precursor to penile cancer, with patients often presenting with red patches or lesions on the penis. Patients with p16+ disease have longer disease-free survival, and those who receive immunotherapy tend to have better responses, although approximately 14% of patients progress to invasive disease.

INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH (2021)

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Article Urology & Nephrology

Predictors of local recurrence and its impact on survival after glansectomy for penile cancer: time to challenge the dogma?

Eduard Roussel et al.

Summary: Pathological T3 stage and presence of high-grade disease were identified as independent predictors of LR after glansectomy for primary pSCC. LR stratification into risk groups based on the number of risk factors present showed significantly different LR development risk. LR was significantly associated with poor overall survival and cancer-specific survival, challenging the dogma of using organ-sparing surgery whenever possible.

BJU INTERNATIONAL (2021)

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Article Urology & Nephrology

Long-term multicentre experience of adjuvant radiotherapy for pN3 squamous cell carcinoma of the penis

Michael Ager et al.

Summary: The study presented long-term adjuvant radiotherapy outcomes in patients with pN3 squamous cell carcinoma of the penis treated at two UK centres. Results showed better survival outcomes with the application of a standard radiotherapy protocol, suggesting a role for adjuvant radiotherapy in managing patients with pN3 SCCp.

BJU INTERNATIONAL (2021)

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Article Urology & Nephrology

Patterns of Recurrence Following Inguinal Lymph Node Dissection for Penile Cancer: Optimizing Surveillance Strategies

Nicholas H. Chakiryan et al.

Summary: This study found that 31.9% of pSCC patients experienced post-ILND recurrence, which was associated with high pN staging. Over 95% of distant, inguinal, and pelvic recurrences occurred within 48 months post-ILND. Local recurrences occurred over a longer timeline, highlighting the necessity of long-term surveillance of the primary site.

JOURNAL OF UROLOGY (2021)

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Article Urology & Nephrology

Phallus Preservation in Penile Cancer Surgery: Patient-reported Aesthetic & Functional Outcomes

Stefanie M. Croghan et al.

Summary: This study assessed patient-reported outcomes of oncoplastic penile reconstruction and found that the majority of patients were satisfied with the appearance of their genitalia and urinary function, with some patients also recovering sexual function. The results of this study strongly support the use of phallus-preserving strategies in eligible patients undergoing penile cancer surgery.

UROLOGY (2021)

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Article Urology & Nephrology

The role of primary inguinal surgical debulking for locally advanced penile cancer followed by reconstruction with myocutaneous flap

Leandro Koifman et al.

Summary: This study evaluated surgical complications and oncological outcomes of patients with locally advanced penile cancer undergoing PRISD and MPFR. Surgery may provide temporary local disease control but has limited impact on long-term survival. Surgical treatment with adjuvant chemotherapy is associated with improved overall survival.

INTERNATIONAL BRAZ J UROL (2021)

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Article Medicine, General & Internal

Penile cancer

Anita Thomas et al.

Summary: Penile squamous cell carcinoma is a rare cancer that affects men in African, Asian, and South American regions, with potential links to HPV infection. Treatment options include local therapy, surgery, and radiotherapy, with advanced cases requiring multimodal management.

NATURE REVIEWS DISEASE PRIMERS (2021)

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Meeting Abstract Oncology

Nivolumab in pretreated metastatic penile squamous cell carcinoma: Results of the penile cohort from the French AcSe prospective program

D. Pouessel et al.

ANNALS OF ONCOLOGY (2021)

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Review Urology & Nephrology

Centralization and Equitable Care in Rare Urogenital Malignancies: The Case for Penile Cancer

Jakob K. Jakobsen et al.

Summary: Centralization of specialized care for rare cancers, such as penile cancer, can lead to improved patient outcomes by providing access to a wider team of specialists and reducing system delays. However, patients may need to travel greater distances to receive care at expert centers, where treatment by experienced surgeons can result in better outcomes.

EUROPEAN UROLOGY FOCUS (2021)

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Article Surgery

Comparative study of perioperative and survival outcomes after video endoscopic inguinal lymphadenectomy (VEIL) and open inguinal lymph node dissection (O-ILND) in the management of inguinal lymph nodes in carcinoma of the penis

Yuvaraja B. Thyavihally et al.

Summary: In the comparison between open inguinal lymph node dissection and video endoscopic inguinal lymphadenectomy in patients with carcinoma of the penis, the latter showed fewer wound-related complications and equivalent survival outcomes, making it a viable alternative option for inguinal lymph node dissection.

JOURNAL OF ROBOTIC SURGERY (2021)

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Review Urology & Nephrology

Systematic Review and Meta-Analysis-Is there a Benefit in Using Neoadjuvant Systemic Chemotherapy for Locally Advanced Penile Squamous Cell Carcinoma?

Mounsif Azizi et al.

JOURNAL OF UROLOGY (2020)

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Article Urology & Nephrology

Adjuvant radiation compares favorably to chemotherapy in patients with carcinoma penis and nodal positivity restricted to groin

Jiten Jaipuria et al.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2020)

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Article Urology & Nephrology

Oncological and Functional Outcomes After Organ-Sparing Plastic Reconstructive Surgery for Penile Cancer

Jaime Perez et al.

UROLOGY (2020)

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Article Urology & Nephrology

DaPeCa-4: outcome in penile cancer patients with N3 disease due to extra nodal extension treated with surgery and chemo-irradiation

Sophia Liff Maibom et al.

SCANDINAVIAN JOURNAL OF UROLOGY (2020)

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Article Urology & Nephrology

Hybrid Indocyanine Green-99mTc-nanocolloid for Single-photon Emission Computed Tomography and Combined Radio- and Fluorescence-guided Sentinel Node Biopsy in Penile Cancer: Results of 740 Inguinal Basins Assessed at a Single Institution

Paolo Dell'Oglio et al.

EUROPEAN UROLOGY (2020)

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Article Oncology

Incidence trends and survival outcomes of penile squamous cell carcinoma: evidence from the Surveillance, Epidemiology and End Results population-based data

Feng Qi et al.

ANNALS OF TRANSLATIONAL MEDICINE (2020)

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Article Urology & Nephrology

Frozen section analysis for organ-conserving surgery in penile cancer: Assessing oncological outcomes and trends of local recurrence

T. Ellul et al.

JOURNAL OF CLINICAL UROLOGY (2020)

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Article Oncology

Adherence to guideline recommendations for lymph node dissection in squamous cell carcinoma of the penis: Effect on survival and complication rates

Francesco A. Mistretta et al.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2019)

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Article Urology & Nephrology

Penile intraepithelial neoplasia: Nomenclature, incidence and progression to malignancy in the Netherlands

Robert J. Hoekstra et al.

INTERNATIONAL JOURNAL OF UROLOGY (2019)

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Review Oncology

Prevalence of human papillomavirus DNA and p16INK4a in penile cancer and penile intraepithelial neoplasia: a systematic review and meta-analysis

Tina Bech Olesen et al.

LANCET ONCOLOGY (2019)

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Article Urology & Nephrology

Surgical and Oncological Outcomes in Patients After Vascularised Flap Reconstruction for Locoregionally Advanced Penile Cancer

Sarah R. Ottenhof et al.

EUROPEAN UROLOGY FOCUS (2019)

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Article Andrology

Long-term outcomes for penile cancer patients presenting with advanced N3 disease requiring a myocutaneous flap reconstruction or primary closure-a retrospective single centre study

Hussain M. Alnajjar et al.

TRANSLATIONAL ANDROLOGY AND UROLOGY (2019)

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Article Oncology

Trends in incidence, mortality and survival of penile squamous cell carcinoma in Norway 1956-2015

Bo T. Hansen et al.

INTERNATIONAL JOURNAL OF CANCER (2018)

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Article Urology & Nephrology

A study into the association between local recurrence rates and surgical resection margins in organ-sparing surgery for penile squamous cell cancer

Denosshan Sri et al.

BJU INTERNATIONAL (2018)

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Article Oncology

Long-term evaluation of urinary, sexual, and quality of life outcomes after brachytherapy for penile carcinoma

Dimitri Gambachidze et al.

BRACHYTHERAPY (2018)

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Article Oncology

A Comparative study of two types of organ-sparing surgeries for early stage penile cancer: Wide local excision vs partial penectomy

Xiang Wan et al.

EJSO (2018)

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Article Urology & Nephrology

Comparing Outcomes of Robotic and Open Inguinal Lymph Node Dissection in Patients with Carcinoma of the Penis

Amitabh Singh et al.

JOURNAL OF UROLOGY (2018)

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Article Oncology

Laser ablation as monotherapy for penile squamous cell carcinoma: A multi-center cohort analysis

Dominic H. Tang et al.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2018)

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Article Surgery

Minimizing Post-operative Complications of Groin Dissection Using Modified Skin Bridge Technique: A Single-Centre Descriptive Study Showing Post-operative and Early Oncological Outcomes

Mukur Dipi Ray et al.

WORLD JOURNAL OF SURGERY (2018)

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Article Oncology

Cross-Sectional Patient-Reported Outcome Measuring of Health-Related Quality of Life With Establishment of Cancer- and Treatment-Specific Functional and Symptom Scales in Patients With Penile Cancer

Desiree Louise Draeger et al.

CLINICAL GENITOURINARY CANCER (2018)

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Article Urology & Nephrology

First-line therapy with dacomitinib, an orally available pan-HER tyrosine kinase inhibitor, for locally advanced or metastatic penile squamous cell carcinoma: results of an open-label, single-arm, single-centre, phase 2 study

Andrea Necchi et al.

BJU INTERNATIONAL (2018)

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Review Dermatology

Imiquimod in the treatment of penile intraepithelial neoplasia: An update

Kristyn Deen et al.

AUSTRALASIAN JOURNAL OF DERMATOLOGY (2017)

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Article Oncology

Bilateral pelvic lymph node dissection for Chinese patients with penile cancer: a multicenter collaboration study

Zai-Shang Li et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2017)

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Article Oncology

Assessment of quality of life in patients surgically treated for penile cancer: Impact of aggressiveness in surgery

Roman Sosnowski et al.

EUROPEAN JOURNAL OF ONCOLOGY NURSING (2017)

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Editorial Material Urology & Nephrology

Need for Evidence and Consensus on Laser Treatment for Management of Select Primary Penile Tumors

Andrew Leone et al.

EUROPEAN UROLOGY (2017)

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Review Urology & Nephrology

Organ Sparing Surgery for Penile Cancer: A Systematic Review

Mohamed H. Kamel et al.

JOURNAL OF UROLOGY (2017)

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Article Urology & Nephrology

Delay to Inguinal Lymph Node Dissection Greater than 3 Months Predicts Poorer Recurrence-Free Survival for Patients with Penile Cancer

Juan Chipollini et al.

JOURNAL OF UROLOGY (2017)

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Review Andrology

Updates on the epidemiology and risk factors for penile cancer

Antoin Douglawi et al.

TRANSLATIONAL ANDROLOGY AND UROLOGY (2017)

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Article Oncology

The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population-based to a more personalized approach to cancer staging

Mahul B. Amin et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2017)

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Article Urology & Nephrology

DaPeCa-2: Implementation of fast-track clinical pathways for penile cancer shortens waiting time and accelerates the diagnostic process - A comparative before-and-after study in a tertiary referral centre in Denmark

Jakob Kristian Jakobsen et al.

SCANDINAVIAN JOURNAL OF UROLOGY (2016)

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Review Urology & Nephrology

Radiocolloid-based dynamic sentinel lymph node biopsy in penile cancer with clinically negative inguinal lymph node: an updated systematic review and meta-analysis

Zi-jun Zou et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY (2016)

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Article Urology & Nephrology

Role of Penile Doppler US in the Preoperative Assessment of Penile Squamous Cell Carcinoma Patients: Results From a Large Prospective Multicenter European Study

Giorgio Bozzini et al.

UROLOGY (2016)

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Article Urology & Nephrology

Predicting postoperative complications of inguinal lymph node dissection for penile cancer in an international multicentre cohort

Jared M. Gopman et al.

BJU INTERNATIONAL (2015)

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Article Oncology

Neoadjuvant Taxane-Based Combination Chemotherapy in Patients With Advanced Penile Cancer

Rosa S. Djajadiningrat et al.

CLINICAL GENITOURINARY CANCER (2015)

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Article Urology & Nephrology

Prophylactic Pelvic Lymph Node Dissection in Patients with Penile Cancer

Rosa S. Djajadiningrat et al.

JOURNAL OF UROLOGY (2015)

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Article Medical Laboratory Technology

Pathological factors, behavior, and histological prognostic risk groups in subtypes of penile squamous cell carcinomas (SCC)

Diego F. Sanchez et al.

SEMINARS IN DIAGNOSTIC PATHOLOGY (2015)

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Article Urology & Nephrology

Sarcopenia as a predictor of complications in penile cancer patients undergoing inguinal lymph node dissection

Pranav Sharma et al.

WORLD JOURNAL OF UROLOGY (2015)

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Article Oncology

Phase II study of docetaxel, cisplatin, and fluorouracil in patients with distantly metastatic penile cancer as first-line chemotherapy

Sheng Zhang et al.

ONCOTARGET (2015)

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Article Urology & Nephrology

Organ-sparing reconstructive surgery in penile cancer: initial experiences at two Swedish referral centres

Ulf Hakansson et al.

SCANDINAVIAN JOURNAL OF UROLOGY (2015)

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Article Urology & Nephrology

Epidermal growth factor receptor-targeted therapy in locally advanced or metastatic squamous cell carcinoma of the penis

Bradley C. Carthon et al.

BJU INTERNATIONAL (2014)

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Article

50 Has centralisation of penile cancer services in the United Kingdom improved survival?

B.E. Ayres et al.

EUROPEAN UROLOGY SUPPLEMENTS (2014)

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Review Oncology

Role of Radiation Therapy in Palliative Care of the Patient With Cancer

Stephen T. Lutz et al.

JOURNAL OF CLINICAL ONCOLOGY (2014)

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Article Pathology

Does the width of the surgical margin of safety or premalignant dermatoses at the negative surgical margin affect outcome in surgically treated penile cancer?

Sven Gunia et al.

JOURNAL OF CLINICAL PATHOLOGY (2014)

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Article Urology & Nephrology

Quality of Life for Patients Treated for Penile Cancer

Jacobien M. Kieffer et al.

JOURNAL OF UROLOGY (2014)

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Article Urology & Nephrology

The Relationship between Characteristics of Inguinal Lymph Nodes and Pelvic Lymph Node Involvement in Penile Squamous Cell Carcinoma: A Single Institution Experience

Giovanni Lughezzani et al.

JOURNAL OF UROLOGY (2014)

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Article Urology & Nephrology

Epidermal Growth Factor Receptor-targeted Therapy in Squamous Cell Carcinoma of the Penis: A Report of 3 Cases

Alev Brown et al.

UROLOGY (2014)

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Article Oncology

Phase II trial of docetaxel, cisplatin and 5FU chemotherapy in locally advanced and metastatic penis cancer (CRUK/09/001)

S. Nicholson et al.

BRITISH JOURNAL OF CANCER (2013)

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Article Urology & Nephrology

Early Wound Complications After Inguinal Lymphadenectomy in Penile Cancer: A Historical Cohort Study and Risk-factor Analysis

Martijn M. Stuiver et al.

EUROPEAN UROLOGY (2013)

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Article Urology & Nephrology

Endoscopic Inguinofemoral Lymphadenectomy-Extended Follow-up

Christian Schwentner et al.

JOURNAL OF ENDOUROLOGY (2013)

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Article Urology & Nephrology

Radical Open Inguinal Lymphadenectomy for Penile Carcinoma: Surgical Technique, Early Complications and Late Outcomes

Leandro Koifman et al.

JOURNAL OF UROLOGY (2013)

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Article Urology & Nephrology

Fascia Lata Preservation During Inguinal Lymphadenectomy for Penile Cancer: Rationale and Outcome

Kai Yao et al.

UROLOGY (2013)

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Article Urology & Nephrology

The risk factors for the presence of pelvic lymph node metastasis in penile squamous cell carcinoma patients with inguinal lymph node dissection

Jian-Ye Liu et al.

WORLD JOURNAL OF UROLOGY (2013)

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Article Urology & Nephrology

Cisplatin and 5-fluorouracil in inoperable, stage IV squamous cell carcinoma of the penis

Giuseppe Di Lorenzo et al.

BJU INTERNATIONAL (2012)

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Article Urology & Nephrology

Treatment of Carcinoma In Situ of the Glans Penis with Topical Chemotherapy Agents

Hussain M. Alnajjar et al.

EUROPEAN UROLOGY (2012)

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Article Oncology

Detection of inguinal lymph node involvement in penile squamous cell carcinoma by 18F-fluorodeoxyglucose PET/CT: A prospective single-center study

Boris Schlenker et al.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2012)

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Article Urology & Nephrology

Role of paclitaxel and platinum-based adjuvant chemotherapy in high-risk penile cancer

Vanita Noronha et al.

UROLOGY ANNALS (2012)

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Article Urology & Nephrology

Paclitaxel in Pretreated Metastatic Penile Cancer: Final Results of a Phase 2 Study

Giuseppe Di Lorenzo et al.

EUROPEAN UROLOGY (2011)

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Article Urology & Nephrology

Glans Resurfacing for the Treatment of Carcinoma In Situ of the Penis: Surgical Technique and Outcomes

Majid Shabbir et al.

EUROPEAN UROLOGY (2011)

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Article Oncology

Proof of Activity of Anti-Epidermal Growth Factor Receptor-Targeted Therapy for Relapsed Squamous Cell Carcinoma of the Penis

Andrea Necchi et al.

JOURNAL OF CLINICAL ONCOLOGY (2011)

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Article Urology & Nephrology

Prognostic Factors for Occult Inguinal Lymph Node Involvement in Penile Carcinoma and Assessment of the High-Risk EAU Subgroup: A Two-Institution Analysis of 342 Clinically Node-Negative Patients

Niels M. Graafland et al.

EUROPEAN UROLOGY (2010)

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Article Oncology

Neoadjuvant Paclitaxel, Ifosfamide, and Cisplatin Chemotherapy for Metastatic Penile Cancer: A Phase II Study

Lance C. Pagliaro et al.

JOURNAL OF CLINICAL ONCOLOGY (2010)

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Article Urology & Nephrology

Controversies in Ilioinguinal Lymphadenectomy

P. K. Hegarty et al.

UROLOGIC CLINICS OF NORTH AMERICA (2010)

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Article Urology & Nephrology

Prospective evaluation of hybrid 18F-fluorodeoxyglucose positron emission tomography/computed tomography in staging clinically node-negative patients with penile carcinoma

Joost A. P. Leijte et al.

BJU INTERNATIONAL (2009)

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Article Urology & Nephrology

Scanning with 18F-FDG-PET/CT for Detection of Pelvic Nodal Involvement in Inguinal Node-Positive Penile Carcinoma

Niels M. Graafland et al.

EUROPEAN UROLOGY (2009)

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Article Oncology

Impact of delay in inguinal lymph node dissection in patients with carcinoma of penis

A Mandhani et al.

INDIAN JOURNAL OF CANCER (2009)

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Article Urology & Nephrology

Non-invasive and minimally invasive staging of regional lymph nodes in penile cancer

Ben Hughes et al.

WORLD JOURNAL OF UROLOGY (2009)

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Article Radiology, Nuclear Medicine & Medical Imaging

The diagnostic accuracy of CT and MRI in the staging of pelvic lymph nodes in patients with prostate cancer:: a meta-analysis

A. M. Hovels et al.

CLINICAL RADIOLOGY (2008)

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Review Urology & Nephrology

Functional imaging in penile cancer: PET/computed tomography, MRI, and sentinel lymph node biopsy

Ullrich G. Mueller-Lisse et al.

CURRENT OPINION IN UROLOGY (2008)

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Article Urology & Nephrology

Recurrence patterns of squamous cell carcinoma of the penis: Recommendations for follow-up based on a two-centre analysis of 700 patients

Joost A. P. Leijte et al.

EUROPEAN UROLOGY (2008)

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Article Urology & Nephrology

Treatment-seeking, aspects of sexual activity and life satisfaction in men with laser-treated penile carcinoma

Elisabet Skeppner et al.

EUROPEAN UROLOGY (2008)

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Article Urology & Nephrology

The role of magnetic resonance imaging in the local staging of penile cancer

Oliver Kayes et al.

EUROPEAN UROLOGY (2007)

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Article Urology & Nephrology

Neoadjuvant chemotherapy followed by aggressive surgical consolidation for metastatic penile squamous cell carcinoma

Carlos Bermejo et al.

JOURNAL OF UROLOGY (2007)

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Article Urology & Nephrology

Pelvic lymph node dissection for penile carcinoma: Extent of inguinal lymph node involvement as an indicator for pelvic lymph node involvement and survival

Anne P. Lont et al.

JOURNAL OF UROLOGY (2007)

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Article Oncology

Presence of high-risk human papillomavirus DNA in penile carcinoma predicts favorable outcome in survival

Anne P. Lont et al.

INTERNATIONAL JOURNAL OF CANCER (2006)

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Article Urology & Nephrology

Patients with penile carcinoma benefit from immediate resection of clinically occult lymph node metastases

BK Kroon et al.

JOURNAL OF UROLOGY (2005)

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Article Gastroenterology & Hepatology

Primary and secondary malignancies of the penis: ultrasound features

M Bertolotto et al.

ABDOMINAL IMAGING (2005)

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Article Urology & Nephrology

Complications of inguinal and pelvic lymphadenectomy for squamous cell carcinoma of the penis: A contemporary series

BA Nelson et al.

JOURNAL OF UROLOGY (2004)

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Article Urology & Nephrology

Long-term followup of penile carcinoma treated with penectomy and bilateral modified inguinal lymphadenectomy

CAL D'Ancona et al.

JOURNAL OF UROLOGY (2004)

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Article Urology & Nephrology

Morbidity of inguinal lymphadenectomy for invasive penile carcinoma

O Bouchot et al.

EUROPEAN UROLOGY (2004)

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Article Urology & Nephrology

Contemporary morbidity from lymphadenectomy for penile squamous cell carcinoma: The M.D. Anderson Cancer Center experience

R Bevan-Thomas et al.

JOURNAL OF UROLOGY (2002)

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