☆ 4.5 Editorial Material

Treating major depressive disorder with mixed features

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2023)

Effectiveness and safety of intravenous valproate in agitation: a systematic review

Olivola Miriam et al.

Summary: Intravenous valproate appears to be effective in reducing agitation in psychiatric patients and generally safe compared to other neuroleptics or antiepileptics. However, the evidence is still not strong as it relies mainly on open-label studies or case series.

PSYCHOPHARMACOLOGY (2022)

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Editorial Material Clinical Neurology

Mechanisms of action of anti-bipolar drugs

Tadafumi Kato

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2022)

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Review Gerontology

Trazodone: a multifunctional antidepressant. Evaluation of its properties and real-world use

Alessandro Cuomo et al.

Summary: Trazodone is effective in treating Major Depressive Disorder, especially in elderly patients and those with neurological comorbidities. It has various formulations and dosages can be tailored to individual patient characteristics. Common side effects include somnolence, dizziness, constipation, and blurred vision, but overall it is well tolerated and can improve symptoms of depression, anxiety, and insomnia.

JOURNAL OF GERONTOLOGY AND GERIATRICS (2021)

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Review Neurosciences