相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity
Nan Shen et al.
FOOD CHEMISTRY (2022)
Epigallocatechin-3-gallate hinders metabolic coupling to suppress colorectal cancer malignancy through targeting aerobic glycolysis in cancer-associated fibroblasts
Shuhai Chen et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2022)
Genistein-Opportunities Related to an Interesting Molecule of Natural Origin
Ewa Garbiec et al.
MOLECULES (2022)
Targeting cancer metabolism in the era of precision oncology
Zachary E. Stine et al.
NATURE REVIEWS DRUG DISCOVERY (2022)
Antihyperglycemic effect of an anthocyanin, cyanidin-3-O-glucoside, is achieved by regulating GLUT-1 via the Wnt/β-catenin-WISP1 signaling pathway
Xiang Ye et al.
FOOD & FUNCTION (2022)
Upregulation of CD36, a Fatty Acid Translocase, Promotes Colorectal Cancer Metastasis by Increasing MMP28 and Decreasing E-Cadherin Expression
James Drury et al.
CANCERS (2022)
The Relationship of Redox With Hallmarks of Cancer: The Importance of Homeostasis and Context
Faliang Xing et al.
FRONTIERS IN ONCOLOGY (2022)
Prostate cancer treatment costs increase more rapidly than for any other cancer-how to reverse the trend?
J. Ellinger et al.
EPMA JOURNAL (2022)
Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care
Alena Mazurakova et al.
EPMA JOURNAL (2022)
Bioavailability of Hesperidin and Its Aglycone Hesperetin-Compounds Found in Citrus Fruits as a Parameter Conditioning the Pro-Health Potential (Neuroprotective and Antidiabetic Activity)-Mini-Review
Kamil Wdowiak et al.
NUTRIENTS (2022)
Anti-prostate cancer protection and therapy in the framework of predictive, preventive and personalised medicine - comprehensive effects of phytochemicals in primary, secondary and tertiary care
Alena Mazurakova et al.
EPMA JOURNAL (2022)
Chemoprevention of Prostate Cancer Cells by Vitamin C plus Quercetin: role of Nrf2 in Inducing Oxidative Stress
Ali Abbasi et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2021)
Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway
Bo Pang et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2021)
FV-429 enhances the efficacy of paclitaxel in NSCLC by reprogramming HIF-1α-modulated FattyAcid metabolism
Yongjian Guo et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2021)
Serine, glycine and one-carbon metabolism in cancer (Review)
Sijing Pan et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2021)
Cancer Focus Lipid metabolism and cancer
Xueli Bian et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2021)
Genetic ablation of FASN attenuates the invasive potential of prostate cancer driven by Pten loss
Debora C. Bastos et al.
JOURNAL OF PATHOLOGY (2021)
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy
Mylene Tajan et al.
NATURE COMMUNICATIONS (2021)
Antitumor Effect of Morusin via G1 Arrest and Antiglycolysis by AMPK Activation in Hepatocellular Cancer
Ah-Reum Cho et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Flavonoids Targeting HIF-1: Implications on Cancer Metabolism
Marek Samec et al.
CANCERS (2021)
How cancer cells remodel lipid metabolism: strategies targeting transcription factors
Do-Won Jeong et al.
LIPIDS IN HEALTH AND DISEASE (2021)
Dietary Luteolin: A Narrative Review Focusing on Its Pharmacokinetic Properties and Effects on Glycolipid Metabolism
Zhenyu Wang et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)
Current methodologies to refine bioavailability, delivery, and therapeutic efficacy of plant flavonoids in cancer treatment
Cijo George Vazhappilly et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2021)
Fine-Tuning Lipid Metabolism by Targeting Mitochondria-Associated Acetyl-CoA-Carboxylase 2 in BRAF(V600E) Papillary Thyroid Carcinoma
Veronica Valvo et al.
THYROID (2021)
Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo
Tiago De Oliveira et al.
CANCERS (2021)
Mitochondrial impairments in aetiopathology of multifactorial diseases: common origin but individual outcomes in context of 3P medicine
Lenka Koklesova et al.
EPMA JOURNAL (2021)
Flavonoids-Macromolecules Interactions in Human Diseases with Focus on Alzheimer, Atherosclerosis and Cancer
Dana Atrahimovich et al.
ANTIOXIDANTS (2021)
Isoangustone A induces autophagic cell death in colorectal cancer cells by activating AMPK signaling
Shunan Tang et al.
FITOTERAPIA (2021)
Role of Flavonoids as Epigenetic Modulators in Cancer Prevention and Therapy
Nishat Fatima et al.
FRONTIERS IN GENETICS (2021)
Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer
Ser Yue Loo et al.
SCIENCE ADVANCES (2021)
Glutathione in the Brain
Koji Aoyama
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Flavonoids against non-physiologic inflammation attributed to cancer initiation, development, and progression-3PM pathways
Peter Kubatka et al.
EPMA JOURNAL (2021)
Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person
Lenka Koklesova et al.
EPMA JOURNAL (2021)
CPT2 down-regulation promotes tumor growth and metastasis through inducing ROS/NFkB pathway in ovarian cancer
Xiaohong Zhang et al.
TRANSLATIONAL ONCOLOGY (2021)
Antibacterial activity and mechanism of plant flavonoids to gram-positive bacteria predicted from their lipophilicities
Ganjun Yuan et al.
SCIENTIFIC REPORTS (2021)
Flavonoids as an effective sensitizer for anti-cancer therapy: insights into multi-faceted mechanisms and applicability towards individualized patient profiles
Alena Liskova et al.
EPMA JOURNAL (2021)
SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis
Lei Feng et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2021)
Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity
Haejin Yoon et al.
MOLECULAR CELL (2021)
The Therapeutic Effects and Mechanisms of Quercetin on Metabolic Diseases: Pharmacological Data and Clinical Evidence
Huan Yi et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)
The Pro-Health Benefits of Morusin Administration-An Update Review
Anita Panek-Krzysko et al.
NUTRIENTS (2021)
Epigenetic Alterations Upstream and Downstream of p53 Signaling in Colorectal Carcinoma
Maja T. Tomicic et al.
CANCERS (2021)
Cholesterol Metabolic Reprogramming in Cancer and Its Pharmacological Modulation as Therapeutic Strategy
Isabella Giacomini et al.
FRONTIERS IN ONCOLOGY (2021)
Targeting ACLY Attenuates Tumor Growth and Acquired Cisplatin Resistance in Ovarian Cancer by Inhibiting the PI3K-AKT Pathway and Activating the AMPK-ROS Pathway (vol 11, 642229, 2021)
Xuan Wei et al.
FRONTIERS IN ONCOLOGY (2021)
Caution, normal BMI: health risks associated with potentially masked individual underweight-EPMA Position Paper 2021
Olga Golubnitschaja et al.
EPMA JOURNAL (2021)
Myricetin: A comprehensive review on its biological potentials
Muhammad Imran et al.
FOOD SCIENCE & NUTRITION (2021)
The Effects of Quercetin on the Gene Expression of Arginine Metabolism Key Enzymes in Human Embryonic Kidney 293 Cells
Saleh Jamehdor et al.
JUNDISHAPUR JOURNAL OF NATURAL PHARMACEUTICAL PRODUCTS (2021)
The ins and outs of serine and glycine metabolism in cancer
Shauni L. Geeraerts et al.
NATURE METABOLISM (2021)
A minireview of quercetin: from its metabolism to possible mechanisms of its biological activities
Hande Gul Ulusoy et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2020)
Flavonoid GL-V9 induces apoptosis and inhibits glycolysis of breast cancer via disrupting GSK-3β-modulated mitochondrial binding of HKII
Yongjian Guo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2020)
Nuclear Factor Erythroid 2-Related Factor 2 in Regulating Cancer Metabolism
Katarina Smolkova et al.
ANTIOXIDANTS & REDOX SIGNALING (2020)
Reprogramming of fatty acid metabolism in cancer
Nikos Koundouros et al.
BRITISH JOURNAL OF CANCER (2020)
Greasing the Wheels of the Cancer Machine: The Role of Lipid Metabolism in Cancer
Marteinn Thor Snaebjornsson et al.
CELL METABOLISM (2020)
Apoptosis Induced by (-)-Epicatechin in Human Breast Cancer Cells is Mediated by Reactive Oxygen Species
Fernando Pereyra-Vergara et al.
MOLECULES (2020)
MicroRNA-195 Functions as a Tumor Suppressor by Directly Targeting Fatty Acid Synthase in Malignant Meningioma
Lai-Rong Song et al.
WORLD NEUROSURGERY (2020)
Arginine deprivation: a potential therapeutic for cancer cell metastasis? A review
Houssam Al-Koussa et al.
CANCER CELL INTERNATIONAL (2020)
NRF2 as a regulator of cell metabolism and inflammation in cancer
Feng He et al.
CARCINOGENESIS (2020)
Synthesis and evaluation of designed PKC modulators for enhanced cancer immunotherapy
Clayton Hardman et al.
NATURE COMMUNICATIONS (2020)
Effect of Hesperidin on Cardiovascular Disease Risk Factors: The Role of Intestinal Microbiota on Hesperidin Bioavailability
Anna Mas-Capdevila et al.
NUTRIENTS (2020)
Anticancer effects of epigallocatechin-3-gallate nanoemulsion on lung cancer cells through the activation of AMP-activated protein kinase signaling pathway
Bing-Huei Chen et al.
SCIENTIFIC REPORTS (2020)
Genoprotective activities of plant natural substances in cancer and chemopreventive strategies in the context of 3P medicine
Lenka Koklesova et al.
EPMA JOURNAL (2020)
Targeting apoptosis in cancer therapy
Benedito A. Carneiro et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2020)
Quercetin overcomes colon cancer cells resistance to chemotherapy by inhibiting solute carrier family 1, member 5 transporter
Yuanyuan Zhou et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2020)
Flavonoids against the Warburg phenotype-concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism
Marek Samec et al.
EPMA JOURNAL (2020)
Metabolic Reprogramming of Chemoresistant Cancer Cells and the Potential Significance of Metabolic Regulation in the Reversal of Cancer Chemoresistance
Xun Chen et al.
METABOLITES (2020)
Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma
Jiao Feng et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
Inhibitors of Fatty Acid Synthesis and Oxidation as Potential Anticancer Agents in Colorectal Cancer Treatment
Paulina Mozolewska et al.
ANTICANCER RESEARCH (2020)
Targeting Lipid Metabolism in Liver Cancer
Malak Alannan et al.
BIOCHEMISTRY (2020)
Hexokinase inhibition using D-Mannoheptulose enhances oncolytic newcastle disease virus-mediated killing of breast cancer cells
Ahmed Ghdhban Al-Ziaydi et al.
CANCER CELL INTERNATIONAL (2020)
FABP5 as a novel molecular target in prostate cancer
Saoirse Elizabeth O'Sullivan et al.
DRUG DISCOVERY TODAY (2020)
Implications of flavonoids as potential modulators of cancer neovascularity
Alena Liskova et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2020)
The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis
Marek Samec et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2020)
ACLY: A biomarker of recurrence in breast cancer
Yue Chen et al.
PATHOLOGY RESEARCH AND PRACTICE (2020)
Upregulation of CPT1A is essential for the tumor-promoting effect of adipocytes in colon cancer
Xiaopeng Xiong et al.
CELL DEATH & DISEASE (2020)
Antiviral Properties of Flavonoids and Delivery Strategies
Paolino Ninfali et al.
NUTRIENTS (2020)
Dissecting the Crosstalk between NRF2 Signaling and Metabolic Processes in Cancer
Janine M. DeBlasi et al.
CANCERS (2020)
Enhanced fatty acid oxidation mediated by CPT1C promotes gastric cancer progression
Tianyi Chen et al.
JOURNAL OF GASTROINTESTINAL ONCOLOGY (2020)
Toxicological Screening of Four Bioactive Citroflavonoids: In Vitro, In Vivo, and In Silico Approaches
Rolffy Ortiz-Andrade et al.
MOLECULES (2020)
PKM2 Promotes Breast Cancer Progression by Regulating Epithelial Mesenchymal Transition
Hui Xiao et al.
ANALYTICAL CELLULAR PATHOLOGY (2020)
Hemistepsin A suppresses colorectal cancer growth through inhibiting pyruvate dehydrogenase kinase activity
Ling Jin et al.
SCIENTIFIC REPORTS (2020)
Lipid Regulatory Proteins as Potential Therapeutic Targets for Ovarian Cancer in Obese Women
Jing Yang et al.
CANCERS (2020)
The NRF2, Thioredoxin, and Glutathione System in Tumorigenesis and Anticancer Therapies
Morana Jaganjac et al.
ANTIOXIDANTS (2020)
Lipid Metabolism and Resistance to Anticancer Treatment
Nicolas Germain et al.
BIOLOGY-BASEL (2020)
Alterations of Lipid Metabolism in Cancer: Implications in Prognosis and Treatment
Lara P. Fernandez et al.
FRONTIERS IN ONCOLOGY (2020)
Cell-free nucleic acid patterns in disease prediction and monitoring-hype or hope?
Adriana Torres Crigna et al.
EPMA JOURNAL (2020)
Important Flavonoids and Their Role as a Therapeutic Agent
Asad Ullah et al.
MOLECULES (2020)
Myricetin bioactive effects: moving from preclinical evidence to potential clinical applications
Yasaman Taheri et al.
BMC COMPLEMENTARY MEDICINE AND THERAPIES (2020)
Down-Regulation of Hypoxia-Inducible Factor-I alpha and Downstream Glucose Transporter Protein Gene by beta-elemene Enhancing the Radiosensitivity of Lung Adenocarcinoma Transplanted Tumor
Wenbo Wu et al.
ONCOTARGETS AND THERAPY (2020)
Synergistic Effect of 3-Bromopyruvate in Combination with Rapamycin Impacted Neuroblastoma Metabolism by Inhibiting Autophagy
Lei Gan et al.
ONCOTARGETS AND THERAPY (2020)
Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma
James S. Lally et al.
CELL METABOLISM (2019)
The Therapeutic Potential of Apigenin
Bahare Salehi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Green tea-induced epigenetic reactivation of tissue inhibitor of matrix metalloproteinase-3 suppresses prostate cancer progression through histone-modifying enzymes
Gauri Deb et al.
MOLECULAR CARCINOGENESIS (2019)
Luteolin, a flavonoid, as an anticancer agent: A review
Muhammad Imran et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Citrus peel flavonoids improve lipid metabolism by inhibiting miR-33 and miR-122 expression in HepG2 cells
Dongxiao Su et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2019)
The role of dietary phytochemicals in the carcinogenesis via the modulation of miRNA expression
Marek Samec et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2019)
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma
Jiao Feng et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Quercetin Inhibits the Proliferation of Glycolysis-Addicted HCC Cells by Reducing Hexokinase 2 and Akt-mTOR Pathway
Hongyan Wu et al.
MOLECULES (2019)
Glut 1 in Cancer Cells and the Inhibitory Action of Resveratrol as A Potential Therapeutic Strategy
Angara Zambrano et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
Swati Dabral et al.
NATURE COMMUNICATIONS (2019)
A Possible Mechanism: Genistein Improves Metabolism and Induces White Fat Browning Through Modulating Hypothalamic Expression of Ucn3, Depp, and Stc1
Liyuan Zhou et al.
FRONTIERS IN ENDOCRINOLOGY (2019)
DNA Methylation Status in Cancer Disease: Modulations by Plant-Derived Natural Compounds and Dietary Interventions
Karin Jasek et al.
BIOMOLECULES (2019)
Fluvastatin Inhibits HMG-CoA Reductase and Prevents Non-Small Cell Lung Carcinogenesis
Tianshun Zhang et al.
CANCER PREVENTION RESEARCH (2019)
ACLY facilitates colon cancer cell metastasis by CTNNB1
Jun Wen et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Alternating consumption of β-glucan and quercetin reduces mortality in mice with colorectal cancer
Jiamei Qi et al.
FOOD SCIENCE & NUTRITION (2019)
Improvement strategies for the oral bioavailability of poorly water-soluble flavonoids: An overview
Juanjuan Zhao et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)
Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism
Alex J. Bott et al.
CELL REPORTS (2019)
Flavonoids as Natural Anti-Inflammatory Agents Targeting Nuclear Factor-Kappa B (NFκB) Signaling in Cardiovascular Diseases: A Mini Review
Ker Woon Choy et al.
FRONTIERS IN PHARMACOLOGY (2019)
Liposomes actively recognizing the glucose transporter GLUT1 and integrin αvβ3 for dual-targeting of glioma
Qiuyi Fu et al.
ARCHIV DER PHARMAZIE (2019)
The Role of Nrf2 Activity in Cancer Development and Progression
Alina-Andreea Zimta et al.
CANCERS (2019)
The Effects and Mechanisms of Cyanidin-3-Glucoside and Its Phenolic Metabolites in Maintaining Intestinal Integrity
Jijun Tan et al.
ANTIOXIDANTS (2019)
Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods
J. Ferlay et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Quercetin inhibition of SREBPs and ChREBP expression results in reduced cholesterol and fatty acid synthesis in C6 glioma cells
Fabrizio Damiano et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2019)
Silibinin inhibits endometrial carcinoma via blocking pathways of STAT3 activation and SREBP1-mediated lipid accumulation
Zhengzheng Shi et al.
LIFE SCIENCES (2019)
Fluctuations of Histone Chemical Modifications in Breast, Prostate, and Colorectal Cancer: An Implication of Phytochemicals as Defenders of Chromatin Equilibrium
Marek Samec et al.
BIOMOLECULES (2019)
Molecular Mechanisms of Action of Genistein in Cancer: Recent Advances
Hardeep Singh Tuli et al.
FRONTIERS IN PHARMACOLOGY (2019)
Xanthohumol inhibits colorectal cancer cells via downregulation of Hexokinases II-mediated glycolysis
Wenbin Liu et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)
The expanded role of fatty acid metabolism in cancer: new aspects and targets
Ming Chen et al.
PRECISION CLINICAL MEDICINE (2019)
Acyl-CoA synthetase short-chain family member 2 (ACSS2) is regulated by SREBP-1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells
Huifen Xu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
Targeting Glutamine Metabolism for Cancer Treatment
Yeon-Kyung Choi et al.
BIOMOLECULES & THERAPEUTICS (2018)
Flavonoid metabolism: the interaction of metabolites and gut microbiota
Kaeko Murota et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2018)
Mutant p53 in breast cancer: potential as a therapeutic target and biomarker
Michael J. Duffy et al.
BREAST CANCER RESEARCH AND TREATMENT (2018)
NRF2 and the Hallmarks of Cancer
Montserrat Rojo de la Vega et al.
CANCER CELL (2018)
Acetyl-CoA Synthetase 2 Promotes Cell Migration and Invasion of Renal Cell Carcinoma by Upregulating Lysosomal-Associated Membrane Protein 1 Expression
Lv Yao et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Quercetin suppresses the mobility of breast cancer by suppressing glycolysis through Akt-mTOR pathway mediated autophagy induction
Lijun Jia et al.
LIFE SCIENCES (2018)
Targeting the PI3K pathway in cancer: are we making headway?
Filip Janku et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Novel anti-obesity effects of beer hops compound xanthohumol: role of AMPK signaling pathway
Janaiya S. Samuels et al.
NUTRITION & METABOLISM (2018)
Downregulation of CPT2 promotes tumorigenesis and chemoresistance to cisplatin in hepatocellular carcinoma
Meihua Lin et al.
ONCOTARGETS AND THERAPY (2018)
Nobiletin Inhibits CD36-Dependent Tumor Angiogenesis, Migration, Invasion, and Sphere Formation Through the Cd36/Stat3/Nf-Kb Signaling Axis
Nipin Sp et al.
NUTRIENTS (2018)
Polyphenols in Colorectal Cancer: Current State of Knowledge including Clinical Trials and Molecular Mechanism of Action
Md Nur Alam et al.
BIOMED RESEARCH INTERNATIONAL (2018)
Fatty acid oxidation: An emerging facet of metabolic transformation in cancer
Yibao Ma et al.
CANCER LETTERS (2018)
Potential Anti-inflammatory Effects of Hesperidin from the Genus Citrus
Silvia Tejada et al.
CURRENT MEDICINAL CHEMISTRY (2018)
Granulin A Synergizes with Cisplatin to Inhibit the Growth of Human Hepatocellular Carcinoma
Gan Qiao et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol
Shi-You Jiang et al.
NATURE COMMUNICATIONS (2018)
Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic Targets
Vera Miranda-Goncalves et al.
FRONTIERS IN GENETICS (2018)
Plant natural modulators in breast cancer prevention: status quo and future perspectives reinforced by predictive, preventive, and personalized medical approach
Sona Uramova et al.
EPMA JOURNAL (2018)
Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models
Ran Wei et al.
FOOD & FUNCTION (2018)
Lipid metabolism reprogramming and its potential targets in cancer
Chunming Cheng et al.
CANCER COMMUNICATIONS (2018)
Roles of membrane lipids in the organization of epithelial cells: Old and new problems
Junichi Ikenouchi
TISSUE BARRIERS (2018)
Therapeutic l-asparaginase: upstream, downstream and beyond
Andre Moreni Lopes et al.
CRITICAL REVIEWS IN BIOTECHNOLOGY (2017)
Arginine-Dual Roles as an Onconutrient and Immunonutrient
Vance L. Albaugh et al.
JOURNAL OF SURGICAL ONCOLOGY (2017)
Cancer metabolism: a therapeutic perspective
Ubaldo E. Martinez-Outschoorn et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance
Jorge S. Burns et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Apigenin Restrains Colon Cancer Cell Proliferation via Targeted Blocking of Pyruvate Kinase M2-Dependent Glycolysis
Shuhua Shan et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)
Plant flavonoids in cancer chemoprevention: role in genome stability
Vazhappilly Cijo George et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2017)
(-)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice
Yu-Fei Yao et al.
LIFE SCIENCES (2017)
Emerging roles of lipid metabolism in cancer metastasis
Xiangjian Luo et al.
MOLECULAR CANCER (2017)
Modulating the therapeutic response of tumours to dietary serine and glycine starvation
Oliver D. K. Maddocks et al.
NATURE (2017)
Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis
Rodrigo Romero et al.
NATURE MEDICINE (2017)
Chrysin loaded nanostructured lipid carriers (NLCs) triggers apoptosis in MCF-7 cancer cells by inhibiting the Nrf2 pathway
Mehdi Sabzichi et al.
PROCESS BIOCHEMISTRY (2017)
Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1α-modulated fatty acid metabolism
Ting Ni et al.
CELL DEATH & DISEASE (2017)
The role of quercetin and vitamin C in Nrf2-dependent oxidative stress production in breast cancer cells
Zohreh Mostafavi-Pour et al.
ONCOLOGY LETTERS (2017)
Suppression of Nrf2 Activity by Chestnut Leaf Extract Increases Chemosensitivity of Breast Cancer Stem Cells to Paclitaxel
Yaejin Woo et al.
NUTRIENTS (2017)
Apigenin sensitizes BEL-7402/ADM cells to doxorubicin through inhibiting miR-101/Nrf2 pathway
Ai-Mei Gao et al.
ONCOTARGET (2017)
Apigenin in cancer therapy: anti-cancer effects and mechanisms of action
Xiaohui Yan et al.
CELL AND BIOSCIENCE (2017)
Luteolin: A Flavonoid that Has Multiple Cardio-Protective Effects and Its Molecular Mechanisms
Yuanyuan Luo et al.
FRONTIERS IN PHARMACOLOGY (2017)
Identification of Epigallocatechin-3-Gallate as an Inhibitor of Phosphoglycerate Mutase 1
Xiaoguang Li et al.
FRONTIERS IN PHARMACOLOGY (2017)
The Warburg effect as an adaptation of cancer cells to rapid fluctuations in energy demand
Tamir Epstein et al.
PLOS ONE (2017)
Membrane lipids and cell signaling
Hannah Sunshine et al.
CURRENT OPINION IN LIPIDOLOGY (2017)
Examination of carnitine palmitoyltransferase 1 abundance in white adipose tissue: implications in obesity research
Jaycob D. Warfel et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2017)
Serum low-density lipoprotein and low-density lipoprotein expression level at diagnosis are favorable prognostic factors in patients with small-cell lung cancer (SCLC)
Ting Zhou et al.
BMC CANCER (2017)
Anti-angiogenesis for cancer revisited: Is there a role for combinations with immunotherapy?
Rakesh R. Ramjiawan et al.
ANGIOGENESIS (2017)
Mycoepoxydiene suppresses HeLa cell growth by inhibiting glycolysis and the pentose phosphate pathway
Kehua Jin et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2017)
Glutamine Metabolism in Cancer: Understanding the Heterogeneity
Ahmad A. Cluntun et al.
TRENDS IN CANCER (2017)
Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells
Lei Tao et al.
BIOCHEMICAL PHARMACOLOGY (2017)
FV-429 induces apoptosis and inhibits glycolysis by inhibiting Akt-mediated phosphorylation of hexokinase II in MDA-MB-231 cells
Yuxin Zhou et al.
MOLECULAR CARCINOGENESIS (2016)
Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG)
Neha Atulkumar Singh et al.
NUTRITION JOURNAL (2016)
Xanthohumol improves dysfunctional glucose and lipid metabolism in diet-induced obese C57BL/6J mice
Cristobal L. Miranda et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2016)
Luteolin Inhibits Proliferation and Induces Apoptosis of Human Placental Choriocarcinoma Cells by Blocking the PI3K/AKT Pathway and Regulating Sterol Regulatory Element Binding Protein Activity
Whasun Lim et al.
BIOLOGY OF REPRODUCTION (2016)
Anti-diabetic effects of luteolin and luteolin-7-O-glucoside on KK-Ay mice
Yanqing Zang et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2016)
Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer
V. Coothankandaswamy et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress
De Huang et al.
CELL RESEARCH (2016)
Luteolin induces cholangiocarcinoma cell apoptosis through the mitochondrial-dependent pathway mediated by reactive oxygen species
Natthawan Kittiratphatthana et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2016)
Soy Isoflavone Genistein-Mediated Downregulation of miR-155 Contributes to the Anticancer Effects of Genistein
Columba de la Parra et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2016)
MicroRNA-1207-5p inhibits hepatocellular carcinoma cell growth and invasion through the fatty acid synthase-mediated Akt/mTOR signalling pathway
Gang Zhao et al.
ONCOLOGY REPORTS (2016)
Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer
Angel Diaz-Lagares et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
The Dual Roles of NRF2 in Cancer
Silvia Menegon et al.
TRENDS IN MOLECULAR MEDICINE (2016)
SCD1 is associated with tumor promotion, late stage and poor survival in lung adenocarcinoma
Jun Huang et al.
ONCOTARGET (2016)
Genistein mediates the selective radiosensitizing effect in NSCLC A549 cells via inhibiting methylation of the keap1 gene promoter region
Xiongxiong Liu et al.
ONCOTARGET (2016)
Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis
Marta Anna Kowalik et al.
ONCOTARGET (2016)
MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4
Candice Sun Hong et al.
CELL REPORTS (2016)
High expression of Fatty Acid-Binding Protein 5 promotes cell growth and metastatic potential of colorectal cancer cells
Koichiro Kawaguchi et al.
FEBS OPEN BIO (2016)
Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Theraphy
Eric C. Woolf et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2016)
Fundamentals of cancer metabolism
Ralph J. DeBerardinis et al.
SCIENCE ADVANCES (2016)
In Vitro Antioxidant versus Metal Ion Chelating Properties of Flavonoids: A Structure-Activity Investigation
Sabri Ahmed Cherrak et al.
PLOS ONE (2016)
Flavonoids: an overview
A. N. Panche et al.
JOURNAL OF NUTRITIONAL SCIENCE (2016)
Targeting cancer metabolism at the plasma membrane by limiting amino acid access through SLC6A14
Alison N. McCracken et al.
BIOCHEMICAL JOURNAL (2015)
Luteolin as an anti-inflammatory and neuroprotective agent: A brief review
Seyed Fazel Nabavi et al.
BRAIN RESEARCH BULLETIN (2015)
Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
Zachary T. Schug et al.
CANCER CELL (2015)
Calycosin and Genistein Induce Apoptosis by Inactivation of HOTAIR/p-Akt Signaling Pathway in Human Breast Cancer MCF-7 Cells
Jian Chen et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)
The acetyl-CoA carboxylase enzyme: a target for cancer therapy?
Chao Wang et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2015)
Fatty acid synthase overexpression: target for therapy and reversal of chemoresistance in ovarian cancer
Dirk O. Bauerschlag et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K
Rupert Courtnay et al.
MOLECULAR BIOLOGY REPORTS (2015)
The Chemopreventive Effect of the Dietary Compound Kaempferol on the MCF-7 Human Breast Cancer Cell Line Is Dependent on Inhibition of Glucose Cellular Uptake
Claudia Azevedo et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2015)
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH
Jihye Yun et al.
SCIENCE (2015)
p53 mutations in colorectal cancer- molecular pathogenesis and pharmacological reactivation
Xiao-Lan Li et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2015)
Epigallocatechin Gallate: A Review of Its Beneficial Properties to Prevent Metabolic Syndrome
Samuel Legeay et al.
NUTRIENTS (2015)
Targeting AMPK for cancer prevention and treatment
Weidong Li et al.
ONCOTARGET (2015)
Epigenetic activities of flavonoids in the prevention and treatment of cancer
Christian Busch et al.
CLINICAL EPIGENETICS (2015)
Luteolin Attenuates Hepatic Steatosis and Insulin Resistance Through the Interplay Between the Liver and Adipose Tissue in Mice with Diet-Induced Obesity
Eun-Young Kwon et al.
DIABETES (2015)
Luteolin inhibits the Nrf2 signaling pathway and tumor growth in vivo
Song Chian et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Regulation of GLUT Transporters by Flavonoids in Androgen-Sensitive and -Insensitive Prostate Cancer Cells
Pedro Gonzalez-Menendez et al.
ENDOCRINOLOGY (2014)
Fisetin Inhibits Human Melanoma Cell Invasion through Promotion of Mesenchymal to Epithelial Transition and by Targeting MAPK and NFκB Signaling Pathways
Harish Chandra Pal et al.
PLOS ONE (2014)
Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1
Dhanya K. Nambiar et al.
ONCOTARGET (2014)
Cancer cells incorporate and remodel exogenous palmitate into structural and oncogenic signaling lipids
Sharon M. Louie et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)
Apigenin sensitizes doxorubicin-resistant hepatocellular carcinoma BEL-7402/ADM cells to doxorubicin via inhibiting PI3K/Akt/Nrf2 pathway
Ai-Mei Gao et al.
CARCINOGENESIS (2013)
Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells
Yong Yang et al.
CELL BIOCHEMISTRY AND FUNCTION (2013)
Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway
Ai-Mei Gao et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2013)
Fatty Acid Synthase Inhibition by Amentoflavone Suppresses HER2/neu (erbB2) Oncogene in SKBR3 Human Breast Cancer Cells
Jin Sun Lee et al.
PHYTOTHERAPY RESEARCH (2013)
Chemistry and Biological Activities of Flavonoids: An Overview
Shashank Kumar et al.
SCIENTIFIC WORLD JOURNAL (2013)
Flavonoids as dietary regulators of nuclear receptor activity
Yishai Avior et al.
FOOD & FUNCTION (2013)
Flavonoid Bioavailability and Attempts for Bioavailability Enhancement
Surangi H. Thilakarathna et al.
NUTRIENTS (2013)
The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics
Pedro M. R. Cruz et al.
FRONTIERS IN PHARMACOLOGY (2013)
Ketone body utilization drives tumor growth and metastasis
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2012)
c-Myc and Cancer Metabolism
Donald M. Miller et al.
CLINICAL CANCER RESEARCH (2012)
Diverse mechanisms of growth inhibition by luteolin, resveratrol, and quercetin in MIA PaCa-2 cells: a comparative glucose tracer study with the fatty acid synthase inhibitor C75
Diane M. Harris et al.
METABOLOMICS (2012)
Association of FABP5 Expression With Poor Survival in Triple-Negative Breast Cancer Implication for Retinoic Acid Therapy
Rong-Zong Liu et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation
Mireille Belanger et al.
CELL METABOLISM (2011)
The role of p53 in cell metabolism
Xing-ding Zhang et al.
ACTA PHARMACOLOGICA SINICA (2010)
Inhibitory effects of four plants flavonoids extracts on fatty acid synthase
Jun CHEN et al.
JOURNAL OF ENVIRONMENTAL SCIENCES (2009)
Epigallocatechin gallate supplementation alleviates diabetes in rodents
Swen Wolfram et al.
JOURNAL OF NUTRITION (2006)
Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity
K Brusselmans et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Flavonoids: Antioxidants or signalling molecules?
RJ Williams et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Genistein-induced changes in gene expression in Panc 1 cells at physiological concentrations of genistein
JF Bai et al.
PANCREAS (2004)
Potential toxicity of flavonoids and other dietary phenolics: Significance for their chemopreventive and anticancer properties
G Galati et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Potential health impacts of excessive flavonoid intake
CF Skibola et al.
FREE RADICAL BIOLOGY AND MEDICINE (2000)