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A Historical Review of the Total Synthesis of Natural Products Developed in Portugal

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WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.202300193

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alkaloids; cyclitols; natural products; quinic acid; total synthesis

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This review summarizes the synthetic strategies developed by several research groups in Portugal for the total synthesis of bioactive natural products, including alkaloids, cyclitols, fatty alcohols, phenylpropanoic acids, gamma-butyrolactones, xanthones, and nucleosides.
Total synthesis of natural products is an important discipline of organic chemistry that has enabled the development of new synthetic methods and strategies for the preparation and study of the structure and reactivity of complex naturally occurring products. In this review we summarize the synthetic strategies developed in Portugal by several research groups for the synthesis of bioactive natural products including alkaloids, cyclitols, fatty alcohols, phenylpropanoic acids, gamma-butyrolactones, xanthones and nucleosides.

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