4.5 Review

Recent advances on the development of graphene-based field-effect transistors, electrochemical biosensors and electrochemiluminescence biosensors

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ELECTROANALYSIS
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WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.202200548

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electrochemical biosensors; electrochemiluminescence biosensors; field-effect transistors; graphene

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Graphene, with its single-atom-layer structure, has sparked tremendous interests in various fields due to its extraordinary mechanical, thermal, chemical and electronic properties. This review focuses on the synthesis method and fabrication strategy of graphene-based materials, as well as the construction and performance of graphene-based biosensors, such as field-effect transistors, electrochemical biosensors, and electrochemiluminescence biosensors. The article also highlights the remaining challenges and future development in this field.
Graphene, a honeycomb lattice of carbon material with single-atom-layer structure, demonstrates extraordinary mechanical, thermal, chemical and electronic properties. Thus, it has sparked tremendous interests in various fields, such as energy storage and conversion devices, field-effect transistors (FET), chemical sensors and biosensors. In this review, we will first focus on the synthesis method of graphene and the fabrication strategy of graphene-based materials. Subsequently, the construction of graphene-based biosensors are introduced, in which three kinds of biosensors are discussed in details, including the FET, electrochemical biosensors and electrochemiluminescence (ECL) biosensors. The performances of the state-of-the-art biosensors on the detection of biomolecules are also displayed. Finally, we also highlight some critical challenges remain to be solved and the development in this field for further research.

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