Natural mycotoxin contamination in dog food: A review on toxicity and detoxification methods

Nowadays, the companion animals (dogs or other pets) are considered as members of the family and have established strong emotional relationships with their owners. Dogs are long lived compared to food animals, so safety, adequacy, and efficacy of dog food is of great importance for their health. Cereals, cereal by-products as well as feedstuffs of plant origin are commonly employed food resources in dry food, yet are potential ingredients for mycotoxins contamination, so dogs are theoretically more vulnerable to exposure when consumed daily. Aflatoxins (AF), deoxynivalenol (DON), fumonisins (FUM), ochratoxin A (OTA), and zearalenone (ZEA) are the most frequent mycotoxins that might present in dog food and cause toxicity on the growth and metabolism of dogs. An understanding of toxicological effects and detoxification methods (physical, chemical, or biological approaches) of mycotoxins will help to improve commercial ped food quality, reduce harm and minimize exposure to dogs. Herein, we outline a description of mycotoxins detected in dog food, toxicity and clinical findings in dogs, as well as methods applied in mycotoxins detoxification. This review aims to provide a reference for future studies involved in the evaluation of the risk, preventative strategies, and clear criteria of mycotoxins for minimizing exposure, reducing harm, and preventing mycotoxicosis in dog.

Automated summary

Nowadays, companion animals such as dogs have become integral members of families and form strong emotional bonds with their owners. Ensuring the safety and nutritional adequacy of dog food is crucial for their health and well-being. However, common ingredients in dry dog food, such as cereals and plant-based feedstuffs, can potentially be contaminated with mycotoxins, which can adversely affect dogs' growth and metabolism. This review provides an overview of the mycotoxins found in dog food, their toxicity to dogs, and different detoxification methods. The aim is to serve as a reference for future studies in evaluating risk, implementing preventive strategies, and setting clear criteria for mycotoxins to minimize exposure, reduce harm, and prevent mycotoxicosis in dogs.