4.3 Article

Biochemical characterization and mutational studies of endonuclease Q from the hyperthermophilic euryarchaeon Thermococcus gammatolerans

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Genetics & Heredity

Biochemical characterization and mutational studies of a novel 3-meth-lyadenine DNA glycosylase II from the hyperthermophilic Thermococcus gammatolerans

Donghao Jiang et al.

Summary: This study reports the biochemical characterization and catalytic mechanism of Tg-AlkA from the hyperthermophilic and radioresistant euryarchaeon Thermococcus gammatolerans. Tg-AlkA is a bi-functional glycosylase with distinct features, and mutational studies reveal crucial catalytic residues and conformational flexibility.

DNA REPAIR (2021)

Article Multidisciplinary Sciences

Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q

Ke Shi et al.

Summary: EndoQ repairs DNA mutations caused by deamination through cleaving the DNA backbone with selectivity depending on DNA distortion and hydrogen bonds with deaminated bases. The enzyme clamps down on a sharply bent DNA substrate with a zinc-binding and C-terminal helical domain swing motion, shaping a deep active-site pocket for accommodating the extruded deaminated base.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Article Multidisciplinary Sciences

Highly accurate protein structure prediction with AlphaFold

John Jumper et al.

Summary: Proteins are essential for life, and accurate prediction of their structures is a crucial research problem. Current experimental methods are time-consuming, highlighting the need for accurate computational approaches to address the gap in structural coverage. Despite recent progress, existing methods fall short of atomic accuracy in protein structure prediction.

NATURE (2021)

Review Biochemistry & Molecular Biology

Archaeal DNA Repair Mechanisms

Craig J. Marshall et al.

BIOMOLECULES (2020)

Article Biochemistry & Molecular Biology

Biochemical characterization of a thermostable endonuclease V from the hyperthermophilic euryarchaeon Thermococcus barophilus Ch5

Yuxiao Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Biochemistry & Molecular Biology

Crystal structure of the novel lesion-specific endonuclease PfuEndoQ from Pyrococcus furiosus

Ken-ichi Miyazono et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Biochemistry & Molecular Biology

A functional endonuclease Q exists in the bacterial domain: identification and characterization of endonuclease Q from Bacillus pumilus

Miyako Shiraishi et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2017)

Article Multidisciplinary Sciences

Cytosine deamination and the precipitous decline of spontaneous mutation during Earth's history

Charles A. Lewis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

PCNA is involved in the EndoQ-mediated DNA repair process in Thermococcales

Miyako Shiraishi et al.

SCIENTIFIC REPORTS (2016)

Review Oncology

DNA repair, genome stability and cancer: a historical perspective

Penny A. Jeggo et al.

NATURE REVIEWS CANCER (2016)

Article Biochemistry & Molecular Biology

EndoQ and EndoV work individually for damaged DNA base repair in Pyrococcus furiosus

Sonoko Ishino et al.

BIOCHIMIE (2015)

Article Biochemistry & Molecular Biology

A novel endonuclease that may be responsible for damaged DNA base repair in Pyrococcus furiosus

Miyako Shiraishi et al.

NUCLEIC ACIDS RESEARCH (2015)

Review Genetics & Heredity

Base excision repair in Archaea: Back to the future in DNA repair

Stefano Grasso et al.

DNA REPAIR (2014)

Review Biochemistry & Molecular Biology

Endonuclease V: an unusual enzyme for repair of DNA deamination

Weiguo Cao

CELLULAR AND MOLECULAR LIFE SCIENCES (2013)

Article Cell Biology

Alternative Excision Repair Pathways

Akira Yasui

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Article Cell Biology

Base Excision Repair

Hans E. Krokan et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Review Microbiology

Genetics techniques for Thermococcus kodakarensis

Travis H. Hileman et al.

FRONTIERS IN MICROBIOLOGY (2012)

Review Cell Biology

The role of endogenous and exogenous DNA damage and mutagenesis

EC Friedberg et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2004)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Review Biochemistry & Molecular Biology

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

A Sancar et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2004)

Article Microbiology

Thermococcus gammatolerans sp nov., a hyperthermophilic archaeon from a deep-sea hydrothermal vent that resists ionizing radiation

E Jolivet et al.

INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY (2003)

Review Biochemistry & Molecular Biology

Repair of deaminated bases in DNA

YW Kow

FREE RADICAL BIOLOGY AND MEDICINE (2002)

Article Multidisciplinary Sciences

Genetic fidelity under harsh conditions:: Analysis of spontaneous mutation in the thermoacidophilic archaeon Sulfolobus acidocaldarius

DW Grogan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)