Sarcopenia: A new route on the map for risk stratification in inflammatory bowel disease

Article Gastroenterology & Hepatology

Sarcopenia is a negative predictive factor for endoscopic remission in patients with Crohn's disease treated with biologics

Mauro Grova et al.

Summary: This study investigates the role of sarcopenia in predicting outcomes in patients with Crohn's disease. The results show that sarcopenia is associated with a lower rate of endoscopic remission after 12 months of therapy and is considered a predictor of lack of endoscopic remission.

DIGESTIVE AND LIVER DISEASE (2023)

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Review Gastroenterology & Hepatology

ECCO Topical Review: Roadmap to Optimal Peri-Operative Care in IBD

Shaji Sebastian et al.

Summary: This article provides expert consensus practice recommendations for peri-operative care in patients with inflammatory bowel diseases (IBD) to optimize surgical outcomes.

JOURNAL OF CROHNS & COLITIS (2023)

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Article Gastroenterology & Hepatology

Sarcopenia Is More Prevalent Among Inflammatory Bowel Disease Patients Undergoing Surgery and Predicts Progression to Surgery Among Medically Treated Patients

James P. Campbell et al.

Summary: Sarcopenia is more prevalent in IBD patients undergoing surgery and predicts the need for surgery in patients starting new biologic therapy. Low albumin and BMI were similar between cohorts, suggesting a unique role for sarcopenia as a relevant clinical marker of lean muscle mass depletion for surgically and medically treated IBD patients.

INFLAMMATORY BOWEL DISEASES (2022)

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Review Gastroenterology & Hepatology

Dietary management of adults with IBD - the emerging role of dietary therapy

Jessica A. Fitzpatrick et al.

Summary: Diet plays a significant role in the management of inflammatory bowel disease (IBD), and dietitians are essential members of the IBD team. This review outlines a four-step approach for dietitians in assessing and managing the diet of IBD patients.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2022)

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Article Nutrition & Dietetics

Impact of Sarcopenia on Clinical Outcomes in a Cohort of Caucasian Active Crohn's Disease Patients Undergoing Multidetector CT-Enterography

Olga Maria Nardone et al.

Summary: This study aims to assess the impact of sarcopenia on clinical outcomes in patients with active CD and investigate its prevalence and predictors. Sarcopenia was observed in a high percentage of Caucasian patients with active CD and was associated with an increased rate of infections.

NUTRIENTS (2022)

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Article Nutrition & Dietetics

Combination of sarcopenia and high visceral fat predict poor outcomes in patients with Crohn's disease

Gurasis Boparai et al.

Summary: In Crohn's disease patients, sarcopenia and visceral fat have significant impact on predicting surgery and disease outcomes. The combination of these parameters has a more detrimental effect on patient outcomes.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2021)

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Review Immunology

Inflammatory Bowel Diseases and Sarcopenia: The Role of Inflammation and Gut Microbiota in the Development of Muscle Failure

Olga Maria Nardone et al.

Summary: Sarcopenia, characterized by muscle mass and function loss, poses a significant health burden in industrialized countries. Factors such as aging, inflammation, mitochondrial dysfunction, and insulin resistance contribute to its pathogenesis. Recent studies show that gut microbiota play a crucial role in the development of muscle failure in inflammatory bowel disease patients.

FRONTIERS IN IMMUNOLOGY (2021)

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Review Gastroenterology & Hepatology