期刊
DIABETES RESEARCH AND CLINICAL PRACTICE
卷 203, 期 -, 页码 -出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.diabres.2023.110793
关键词
Gestation diabetes mellitus; Maternal obesity in pregnancy; Pregnancy in diabetes; Pregnancy outcome/epidemiology; Australia/epidemiology
A study conducted in a tertiary hospital in Melbourne, Australia found that the prevalence of gestational diabetes mellitus (GDM) has significantly increased according to the IADPSG criteria, accompanied by an increase in type 2 diabetes (T2DM), maternal obesity, and large-for-gestational age (LGA), without improvement in perinatal outcomes.
Background: The International Association of Diabetes in Pregnancy Study Groups (IADPSG) gestational diabetes mellitus (GDM) criteria have been heavily scrutinised with concerns that the consequent GDM prevalence increase has not been associated with improved perinatal outcomes.Aims: At a tertiary hospital in Melbourne, Australia we aimed to evaluate prevalence trends for GDM, type 2 diabetes (T2DM), maternal obesity and large-for-gestational age (LGA) and assess changes in perinatal outcomes following IADPSG criteria uptake in 2015.Methods: A retrospective cohort study of singleton births from 20 weeks' gestation was conducted between 1st January 2011 and 31st December 2020. Maternal characteristics and perinatal outcomes were extracted from medical records.Results: 52,795 pregnancies were included. GDM prevalence increased 2.7 times from 8.9% in 2011 to 23.7% in 2020 and increased annually by 8.59% (95%CI 7.77, 9.42). The rate of T2DM increased annually by 11.69% (95%CI 7.72, 16.67). Obesity prevalence increased annually by 3.18% (95%CI 2.58, 3.78). Induction of labour (IOL) prevalence increased annually by 8.35% (95%CI 5.69, 11.06). LGA prevalence remained unchanged. Increasing maternal obesity was the major contributing factor for LGA prevalence.Conclusions: From 2011 to 2020 GDM, obesity and T2DM prevalence increased significantly, with associated increased IOL, without change in LGA rates. Prospective studies are required to explore interactions between GDM, obesity, LGA and obstetric interventions.
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