相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Phoneutria nigriventer Tx3-3 peptide toxin reduces fibromyalgia symptoms in mice
Claudia Pedron et al.
NEUROPEPTIDES (2021)
Migraine: Calcium Channels and Glia
Marta Kowalska et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Neuroprotective effects of the CTK 01512-2 toxin against neurotoxicity induced by 3-nitropropionic acid in rats
Flavia Tasmin Techera Antunes et al.
NEUROTOXICOLOGY (2021)
Protective effect of a spider recombinant toxin in a murine model of Huntington's disease
Julliane V. Joviano-Santos et al.
NEUROPEPTIDES (2021)
Advances in venom peptide drug discovery: where are we at and where are we heading?
Taylor B. Smallwood et al.
EXPERT OPINION ON DRUG DISCOVERY (2021)
Analgesic effects of Phα1β toxin: a review of mechanisms of action involving pain pathways
Juliana Figueira da Silva et al.
JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES (2021)
Pain-related toxins in scorpion and spider venoms: a face to face with ion channels
Sylvie Diochot
JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES (2021)
Recombinant peptide derived from the venom the Phoneutria nigriventer spider relieves nociception by nerve deafferentation
Flavia Tasmin Techera Antunes et al.
NEUROPEPTIDES (2020)
Phoneutria toxin PnTx3-5 inhibits TRPV1 channel with antinociceptive action in an orofacial pain model
Elizete Maria Rita Pereira et al.
NEUROPHARMACOLOGY (2020)
Analgesic effects of the CTK 01512-2 toxin in different models of orofacial pain in rats
Emanuelle Sistherenn Caminski et al.
PHARMACOLOGICAL REPORTS (2020)
From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery
Karla de Castro Figueiredo Bordon et al.
FRONTIERS IN PHARMACOLOGY (2020)
The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises
Srinivasa N. Raja et al.
PAIN (2020)
Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Theo Vos et al.
LANCET (2020)
Analgesic and side effects of intravenous recombinant Phα1β
Flavia Karine Rigo et al.
JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES (2020)
HNTX-III Alleviates Inflammatory and Neuropathic Pain in Animal Models
Yu Liu et al.
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2019)
Versatile spider venom peptides and their medical and agricultural applications
Natalie J. Saez et al.
TOXICON (2019)
Mechanically Activated Piezo Channels Mediate Touch and Suppress Acute Mechanical Pain Response in Mice
Mingmin Zhang et al.
CELL REPORTS (2019)
Phα1β Spider Toxin Reverses Glial Structural Plasticity Upon Peripheral Inflammation
Helia Tenza-Ferrer et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Spider Venom: Components, Modes of Action, and Novel Strategies in Transcriptomic and Proteomic Analyses
Nicolas Langenegger et al.
TOXINS (2019)
Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin
Hui Xu et al.
CELL (2019)
Animal Venom Peptides as a Treasure Trove for New Therapeutics Against Neurodegenerative Disorders
Xinwang Yang et al.
CURRENT MEDICINAL CHEMISTRY (2019)
Engineering Nav1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics
Justin K. Murray et al.
ACS CHEMICAL BIOLOGY (2019)
The NA(v)1.7 blocker protoxin II reduces burn injury-induced spinal nociceptive processing
Jose Vicente Torres-Perez et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2018)
Neuroprotective Effects of Psalmotoxin-1, an Acid-Sensing Ion Channel (ASIC) Inhibitor, in Ischemia Reperfusion in Mouse Eyes
Adnan Dibas et al.
CURRENT EYE RESEARCH (2018)
Structural Characterization and Disulfide Assignment of Spider Peptide Phα1β by Mass Spectrometry
Kelly L. Wormwood et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2018)
Beneficial Effects of the Calcium Channel Blocker CTK 01512-2 in a Mouse Model of Multiple Sclerosis
Rodrigo B. M. Silva et al.
MOLECULAR NEUROBIOLOGY (2018)
Calcium Channels, Synaptic Plasticity, and Neuropsychiatric Disease
Evanthia Nanou et al.
NEURON (2018)
Direct evidence for high affinity blockade of NaV1.6 channel subtype by huwentoxin-IV spider peptide, using multiscale functional approaches
Tania C. Goncalves et al.
NEUROPHARMACOLOGY (2018)
Pharmacological characterization of potent and selective Nav1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V
Bryan D. Moyer et al.
PLOS ONE (2018)
Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors
Tania Chernov-Rogan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
GpTx-1 and [Ala(5), Phe(6), Leu(26), Arg(28)]GpTx-1, two peptide Na(V)1.7 inhibitors: analgesic and tolerance properties at the spinal level
Chao Chen et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis
Bin Wu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Neuroprotective effects of inhibitors of Acid-Sensing ion channels (ASICs) in optic nerve crush model in rodents
Dorota L. Stankowska et al.
CURRENT EYE RESEARCH (2018)
The peptide Phα1β, from spider venom, acts as a TRPA1 channel antagonist with antinociceptive effects in mice
Raquel Tonello et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Acid-sensing ion channel (ASIC) structure and function: Insights from spider, snake and sea anemone venoms
Ben Cristofori-Armstrong et al.
NEUROPHARMACOLOGY (2017)
Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a
Irene R. Chassagnon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Pathology of Neurodegenerative Diseases
Brittany N. Dugger et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor
M. Flinspach et al.
SCIENTIFIC REPORTS (2017)
Disease Modifying Effects of the Spider Toxin Parawixin2 in the Experimental Epilepsy Model
Livea Dornela Godoy et al.
TOXINS (2017)
The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant
Sassan Rahnama et al.
PLOS ONE (2017)
Effect of the spider toxin Tx3-3 on spinal processing of sensory information in naive and neuropathic rats: an in vivo electrophysiological study
Gerusa D. Dalmolin et al.
PAIN REPORTS (2017)
Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4
Constanza Alcaino et al.
CHANNELS (2017)
CADD Modeling of Multi-Target Drugs Against Alzheimer's Disease
Pravin Ambure et al.
CURRENT DRUG TARGETS (2017)
Neuroprotective Effects of Paeoniflorin on 6-OHDA-Lesioned Rat Model of Parkinson's Disease
Xiao-Su Gu et al.
NEUROCHEMICAL RESEARCH (2016)
Antinociceptive effect of a novel armed spider peptide Tx3-5 in pathological pain models in mice
Sara M. Oliveira et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
The Phoneutria nigriventer spider toxin, PnTx4-5-5, promotes neuronal survival by blocking NMDA receptors
Flavia R. Silva et al.
TOXICON (2016)
Prevalence of chronic pain in the UK: a systematic review and meta-analysis of population studies
A. Fayaz et al.
BMJ OPEN (2016)
PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina
Nancy Scardua Binda et al.
TOXINS (2016)
Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain
Jennifer R. Deuis et al.
TOXINS (2016)
Sustained inhibition of the NaV1.7 sodium channel by engineered dimers of the domain II binding peptide GpTx-1
Justin K. Murray et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a
Claudia A. McCarthy et al.
NEUROPHARMACOLOGY (2015)
Spinal blockage of P/Q- or N-type voltage-gated calcium channels modulates functional and symptomatic changes related to haemorrhagic cystitis
R. B. M. Silva et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Phα1β, a Peptide from the Venom of the Spider Phoneutria Nigriventer Shows Antinociceptive Effects after Continuous Infusion in a Neuropathic Pain Model in Rats
Fernanda Rosa et al.
ANESTHESIA AND ANALGESIA (2014)
More Than a Pore: Ion Channel Signaling Complexes
Amy Lee et al.
JOURNAL OF NEUROSCIENCE (2014)
Action of Phα1β, a Peptide From the Venom of the Spider Phoneutria nigriventer, on the Analgesic and Adverse Effects Caused by Morphine in Mice
Raquel Tonello et al.
JOURNAL OF PAIN (2014)
Effects of the calcium channel blockers Phα1β and ω-conotoxin MVIIA on capsaicin and acetic acid-induced visceral nociception in mice
Danuza Montijo Diniz et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2014)
Analgesic Effects of Huwentoxin-IV on Animal Models of Inflammatory and Neuropathic Pain
Yu Liu et al.
PROTEIN AND PEPTIDE LETTERS (2014)
Two tarantula venom peptides as potent and differential NaV channels blockers
Ronit S. Cherki et al.
TOXICON (2014)
Block of T-type calcium channels by protoxins I and II
Chris Bladen et al.
MOLECULAR BRAIN (2014)
Synthesis and Analgesic Effects of μ-TRTX-Hhn1b on Models of Inflammatory and Neuropathic Pain
Yu Liu et al.
TOXINS (2014)
Spider peptide Phα1β induces analgesic effect in a model of cancer pain
Flavia Karine Rigo et al.
CANCER SCIENCE (2013)
Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
Michael H. Yan et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Structure and Function of Hainantoxin-III, a Selective Antagonist of Neuronal Tetrodotoxin-sensitive Voltage-gated Sodium Channels Isolated from the Chinese Bird Spider Ornithoctonus hainana
Zhonghua Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Potency optimization of Huwentoxin-IV on hNav1.7: A neurotoxin TTX-S sodium-channel antagonist from the venom of the Chinese bird-eating spider Selenocosmia huwena
Jefferson D. Revell et al.
PEPTIDES (2013)
Effect of ω-conotoxin MVIIA and Phα1β on paclitaxel-induced acute and chronic pain
Flavia K. Rigo et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2013)
Major channels involved in neuropsychiatric disorders and therapeutic perspectives
Paola Imbrici et al.
Frontiers in Genetics (2013)
The Mechanosensitive Ion Channel Piezo1 Is Inhibited by the Peptide GsMTx4
Chilman Bae et al.
BIOCHEMISTRY (2011)
The Antinociceptive Efficacy of HWTX-I Epidurally Administered in Rheumatoid Arthritis Rats
Z. Wen Tao et al.
INTERNATIONAL JOURNAL OF SPORTS MEDICINE (2011)
Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death
Thomas W. Sherwood et al.
JOURNAL OF NEUROSCIENCE (2011)
Antinociceptive effect of Brazilian armed spider venom toxin Tx3-3 in animal models of neuropathic pain
Gerusa Duarte Dalmolin et al.
PAIN (2011)
PHONEUTRIA SPIDER TOXINS BLOCK ISCHEMIA-INDUCED GLUTAMATE RELEASE AND NEURONAL DEATH OF CELL LAYERS OF THE RETINA
Rafael Mourao Agostini et al.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2011)
From Toxins Targeting Ligand Gated Ion Channels to Therapeutic Molecules
Adak Nasiripourdori et al.
TOXINS (2011)
Identification of a Calcium Permeable Human Acid-sensing Ion Channel 1 Transcript Variant
Erin N. Hoagland et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Nociceptors: the sensors of the pain pathway
Adrienne E. Dubin et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Ion channels as novel therapeutic targets in the treatment of pain
Alistair Mathie
JOURNAL OF PHARMACY AND PHARMACOLOGY (2010)
Spider-Venom Peptides as Therapeutics
Natalie J. Saez et al.
TOXINS (2010)
Phoneutria Spider Toxins Block Ischemia-Induced Glutamate Release, Neuronal Death, and Loss of Neurotransmission in Hippocampus
Ana Cristina do Nascimento Pinheiro et al.
HIPPOCAMPUS (2009)
TRPC1 and TRPC6 Channels Cooperate with TRPV4 to Mediate Mechanical Hyperalgesia and Nociceptor Sensitization
Nicole Alessandri-Haber et al.
JOURNAL OF NEUROSCIENCE (2009)
Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain II voltage sensor in the closed configuration
Yucheng Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
ProTx-II, a Selective Inhibitor of Nav1.7 Sodium Channels, Blocks Action Potential Propagation in Nociceptors
William A. Schmalhofer et al.
MOLECULAR PHARMACOLOGY (2008)
Tx3-4 a toxin from the venom of spider Phoneutria nigriventer blocks calcium channels associated with exocytosis
Celio Jose de Castro et al.
NEUROSCIENCE LETTERS (2008)
A tarantula spider toxin, GsMTx4, reduces mechanical and neuropathic pain
Seung Pyo Park et al.
PAIN (2008)
Analgesic effect in rodents of native and recombinant Phα1β toxin, a high-voltage-activated calcium channel blocker isolated from armed spider venom
Alessandra H. Souza et al.
PAIN (2008)
The cross channel activities of spider neurotoxin huwentoxin-I on rat dorsal root ganglion neurons
Meichi Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Permeating protons contribute to tachyphylaxis of the acid-sensing ion channel (ASIC) 1a
Xuanmao Chen et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Isolation and characterization of Jingzhaotoxin-V, a novel neurotoxin from the venom of the spider Chilobrachys jingzhao
Xiongzhi Zeng et al.
TOXICON (2007)
ProTx-1 and ProTx-II: Gating modifiers of voltage-gated sodium channels
Birgit T. Priest et al.
TOXICON (2007)
Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia
Giuseppe Pignataro et al.
BRAIN (2007)
Nonclinical safety of ziconotide: An intrathecal analgesic of a new pharmaceutical class
Michael J. Skov et al.
INTERNATIONAL JOURNAL OF TOXICOLOGY (2007)
A century of Alzheimer's disease
Michel Goedert et al.
SCIENCE (2006)
A common mechanism underlies stretch activation and receptor activation of TRPC6 channels
Maria A. Spassova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Interaction of acid-sensing ion channel (ASIC) 1 with the tarantula toxin psalmotoxin 1 is state dependent
XM Chen et al.
JOURNAL OF GENERAL PHYSIOLOGY (2006)
Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death
J Gao et al.
NEURON (2005)
Inhibition of high voltage-activated calcium channels by spider toxin PnTx3-6
LB Vieira et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Antinociceptive effects of intrathecally administered huwentoxin-I, a selective N-type calcium channel blocker, in the formalin test in conscious rats
JQ Chen et al.
TOXICON (2005)
An overview of peptide toxins from the venom of the Chinese bird spider Selenocosmia huwena Wang [=Ornithoctonus huwena (Wang)]
SP Liang
TOXICON (2004)
Intrathecal ziconotide in the treatment of refractory pain in patients with cancer or AIDS - A randomized controlled trial
PS Staats et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)
Neuroprotection in ischemia: Blocking calcium-permeable acid-sensing ion channels
ZG Xiong et al.
CELL (2004)
3-Nitropropionic acid-induced neurotoxicity - assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy
AL Brownell et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Inhibition of neuronal tetrodotoxin-sensitive Na+ channels by two spider toxins:: hainantoxin-III and hainantoxin-IV
XC Xiao et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2003)
Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels
P Escoubas et al.
PROTEIN SCIENCE (2003)
PnTx3-6 a spider neurotoxin inhibits K+-evoked increase in [Ca2+]i and Ca2+-dependent glutamate release in synaptosomes
LB Vieira et al.
NEUROCHEMISTRY INTERNATIONAL (2003)
Two tarantula peptides inhibit activation of multiple sodium channels
RE Middleton et al.
BIOCHEMISTRY (2002)
Function and solution structure of huwentoxin-IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena
K Peng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Phoneutria nigriventer venom:: A cocktail of toxins that affect ion channels
MV Gomez et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2002)
Phoneutria nigriventer ω-phonetoxin IIA blocks the Cav2 family of calcium channels and interacts with ω-conotoxin-binding sites
RG Dos Santos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The effect of Huwentoxin-I on Ca2+ channels in differentiated NG108-15 cells, a patch-clamp study
K Peng et al.
TOXICON (2001)
Spider neurotoxins block the β scorpion toxin-induced calcium uptake in rat brain cortical synaptosomes
DM Miranda et al.
BRAIN RESEARCH BULLETIN (2001)
Purification and amino acid sequence of a highly insecticidal toxin from the venom of the Brazilian spider Phoneutria nigriventer which inhibits NMDA-evoked currents in rat hippocampal neurones
SG de Figueiredo et al.
TOXICON (2001)
Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels
P Escoubas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Inhibition of glutamate uptake by Tx3-4 is dependent on the redox state of cysteine residues
HJ Reis et al.
NEUROREPORT (2000)
Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels
TM Suchyna et al.
JOURNAL OF GENERAL PHYSIOLOGY (2000)
Inhibition of neuronal high-voltage activated calcium channels by the omega-Phoneutria nigriventer Tx3-3 peptide toxin
RM Leao et al.
NEUROPHARMACOLOGY (2000)