期刊
CURRENT ORGANIC SYNTHESIS
卷 20, 期 8, 页码 838-869出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1570179420666230316094435
关键词
Quinazoline; quinazolinone; anti-tubercular activity; SAR; heterocycles; drug
Multiple drugs based on heterocyclic molecules have been developed for treating various symptoms. Quinazoline and quinazolinone derivatives exhibit extensive pharmacological and biological characteristics, including their potency as anti-tubercular agents. This review summarizes the reported anti-tubercular drugs designed using quinazoline and quinazolinone derivatives.
Multiple potential drugs have been developed based on the heterocyclic molecules for the treatment of different symptoms. Among the existing heterocyclic molecules, quinazoline and quinazolinone derivatives have been found to exhibit extensive pharmacological and biological characteristics. One significant property of these molecules is their potency as anti-tubercular agents. Thus, both quinazoline and quinazolinone derivatives are modified using different functional groups as substituents for investigating their anti-tubercular activities. We present a summary of the reported anti-tubercular drugs, designed using quinazoline and quinazolinone derivatives, in this review.
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