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Review
Biochemistry & Molecular Biology
Prabir Kumar Kulabhusan et al.
Summary: Viral infections can be fatal to humans and animals, and early detection is crucial for effective treatment. Current detection methods face challenges in sensitivity and quantification of the virus. Aptamers, synthetic binding molecules, show promise in viral detection with their stability and adaptability. This review discusses advances in aptamer-based viral detection platforms, including electrochemical, optical, and colorimetric methods for detecting viruses like SARS-Cov-2. Aptamers could revolutionize the design of high-throughput biosensors for viruses and other biomedical applications in the future.
CURRENT MEDICINAL CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Adrianna Maria Piasek et al.
Summary: Cancer diseases, particularly skin cancers, pose a significant health threat. Early diagnosis is crucial for effective treatment, and aptamers offer novel possibilities in this area by specifically binding cancer biomarkers. They are increasingly used as diagnostic probes in imaging and targeted therapy. This review highlights the recent advances achieved in skin cancer diagnostics and treatment through the combination of aptamers with basic or modern technologies.
CURRENT MEDICINAL CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Sayali Upasham et al.
Summary: In the past decade, researchers have explored electrochemical sensing to create wearable platforms for point-of-use applications. These platforms can track clinically relevant biomarkers and assess the user's health comprehensively. Aptamer-based sensing is gaining popularity due to its operational advantages such as stability, sensitivity, and label-free detection. This paper provides an overview of the current state of electrochemical aptasensing, focusing on the detection of biomarkers for lifestyle and chronic disease monitoring and discussing the challenges and prospects in this field.
CURRENT MEDICINAL CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Ajinkya Nene et al.
Summary: Black phosphorus nanostructures, including nanosheets, quantum dots, and other particles, have gained significant interest due to their high surface area, photothermal conversion efficacy, excellent biocompatibility, and high charge carrier mobility. These properties make them promising candidates for biosensing platforms and other applications such as drug delivery, data storage devices, and sensing devices.
CURRENT MEDICINAL CHEMISTRY
(2023)
Review
Medical Laboratory Technology
Ahmad Mobed et al.
Summary: Parkinson's disease is a critical disorder affecting the elderly worldwide, with over six million people impacted. Advances in electrochemical techniques offer promising tools for PD diagnosis and monitoring.
CLINICA CHIMICA ACTA
(2021)
Article
Medicine, Research & Experimental
Robert M. Califf
EXPERIMENTAL BIOLOGY AND MEDICINE
(2018)
Article
Chemistry, Analytical
Zhou Ling et al.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2011)
