4.1 Article

PTD-FGF2 Attenuates Elastase Induced Emphysema in Mice and Alveolar Epithelial Cell Injury

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Cell & Tissue Engineering

Emerging role of exosomes in the pathology of chronic obstructive pulmonary diseases; destructive and therapeutic properties

Hadi Rajabi et al.

Summary: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally, mainly due to chronic inflammation and pathological remodeling leading to decreased life span. Recent studies have found that immune cell-derived exosomes play a negative role in the pathogenesis of COPD.

STEM CELL RESEARCH & THERAPY (2022)

Review Respiratory System

Extracellular vesicles and chronic obstructive pulmonary disease (COPD): a systematic review

Nancy Gomez et al.

Summary: This systematic review examines the role of extracellular vesicles (EVs) in the pathogenesis and diagnosis of Chronic Obstructive Pulmonary Disease (COPD). The research found that EVs are involved in the mechanism of COPD pathogenesis, derived from various cell types and containing modified levels of miRNAs. The findings suggest that EVs could be a potential method for COPD diagnosis and progress monitoring.

RESPIRATORY RESEARCH (2022)

Article Multidisciplinary Sciences

Different expression of circulating microRNA profile and plasma SP-D in Tibetan COPD patients

Xue-feng Shi et al.

Summary: This study identifies distinct miRNA signatures in Tibetan COPD patients that could be used as diagnostic biomarkers or describe differential molecular mechanisms. Functional analysis of the target genes of differentially expressed miRNAs showed their influence on cell morphogenesis and signaling pathways. Age, plasma miRNA, and SP-D mRNA expression were found to be correlated with COPD risk factors.

SCIENTIFIC REPORTS (2022)

Review Immunology

Cellular and functional heterogeneity of the airway epithelium

Jordan D. Davis et al.

Summary: This article discusses the cellular and functional heterogeneity along the airway epithelium, as well as how this knowledge can be used to design more effective targeted therapeutics.

MUCOSAL IMMUNOLOGY (2021)

Article Genetics & Heredity

Identifying miRNA-mRNA Networks Associated With COPD Phenotypes

Yonghua Zhuang et al.

Summary: The study utilized Sparse Multiple Canonical Correlation Network to integrate miRNA and RNA sequencing data, identifying miRNA-mRNA networks associated with COPD-related phenotypes, showing that partial covariate adjustment can improve network identification.

FRONTIERS IN GENETICS (2021)

Article Cell Biology

Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury

Derek C. Liberti et al.

Summary: Fgfr2 signaling plays a crucial role in maintaining the fate of AT2 cells during lung alveolus regeneration, balancing proliferation and differentiation processes. Cell division and differentiation are uncoupled during alveolar regeneration.

CELL REPORTS (2021)

Review Biochemistry & Molecular Biology

Neutrophil Elastase and Chronic Lung Disease

Judith A. Voynow et al.

Summary: NE plays a role in chronic inflammatory airway diseases and can affect the airway environment, inducing airway remodeling and disrupting epithelial repair.

BIOMOLECULES (2021)

Review Pharmacology & Pharmacy

Kinase inhibitors in the treatment of obstructive pulmonary diseases

Amy E. Defnet et al.

CURRENT OPINION IN PHARMACOLOGY (2020)

Review Cell Biology

RNA delivery by extracellular vesicles in mammalian cells and its applications

Killian O'Brien et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Article Multidisciplinary Sciences

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

Masahiro Yoshida et al.

NATURE COMMUNICATIONS (2019)

Article Respiratory System

Quantitative lung morphology: semi-automated measurement of mean linear intercept

George Crowley et al.

BMC PULMONARY MEDICINE (2019)

Review Physiology

Cell Death in the Lung: The ApoptosisNecroptosis Axis

Maor Sauler et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 81 (2019)

Review Physiology

Cellular senescence in the lung across the age spectrum

Pavan Parikh et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2019)

Review Medicine, General & Internal

Chronic obstructive pulmonary disease: MicroRNAs and exosomes as new diagnostic and therapeutic biomarkers

Jafar Salimian et al.

JOURNAL OF RESEARCH IN MEDICAL SCIENCES (2018)

Article Multidisciplinary Sciences

MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology

Florence Sonneville et al.

NATURE COMMUNICATIONS (2017)

Review Pharmacology & Pharmacy

Role of Proteases in Chronic Obstructive Pulmonary Disease

Kailash C. Pandey et al.

FRONTIERS IN PHARMACOLOGY (2017)

Article Biochemistry & Molecular Biology

Fibroblast Growth Factor 2 Is Required for Epithelial Recovery, but Not for Pulmonary Fibrosis, in Response to Bleomycin

Robert D. Guzy et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2015)

Article Respiratory System

Unravelling the complexity of COPD by microRNAs: it's a small world after all

Emmanuel T. Osei et al.

EUROPEAN RESPIRATORY JOURNAL (2015)

Article Medicine, General & Internal

Chronic obstructive pulmonary disease

Peter J. Barnes et al.

NATURE REVIEWS DISEASE PRIMERS (2015)

Article Physiology

CCN1 secretion and cleavage regulate the lung epithelial cell functions after cigarette smoke

Hyung-Geun Moon et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)

Article Biotechnology & Applied Microbiology

Extracellular vesicles: biology and emerging therapeutic opportunities

Samir EL Andaloussi et al.

NATURE REVIEWS DRUG DISCOVERY (2013)

Review Medicine, Research & Experimental

Pathogenesis of chronic obstructive pulmonary disease

Rubin M. Tuder et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Article Critical Care Medicine

MicroRNA Expression in Induced Sputum of Smokers and Patients with Chronic Obstructive Pulmonary Disease

Geert R. Van Pottelberge et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Biochemistry & Molecular Biology

Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-γ

Byung-Jae Lee et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2011)

Article Biochemistry & Molecular Biology

Elevated miR-155 Promotes Inflammation in Cystic Fibrosis by Driving Hyperexpression of Interleukin-8

Sharmistha Bhattacharyya et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biotechnology & Applied Microbiology

Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung

Alberto Izzotti et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2011)

Article Critical Care Medicine

Reduced miR-146a Increases Prostaglandin E2 in Chronic Obstructive Pulmonary Disease Fibroblasts

Tadashi Sato et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)

Article Biochemistry & Molecular Biology

MicroRNA: Biogenesis, Function and Role in Cancer

Leigh-Ann MacFarlane et al.

CURRENT GENOMICS (2010)

Article Biochemistry & Molecular Biology

The Cytokine Network in Chronic Obstructive Pulmonary Disease

Peter J. Barnes

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2009)

Article Multidisciplinary Sciences

MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium

Frank Schembri et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Immunology

Immunology of asthma and chronic obstructive pulmonary disease

Peter J. Barnes

NATURE REVIEWS IMMUNOLOGY (2008)

Article Critical Care Medicine

Alveolar cell senescence in patients with pulmonary emphysema

Takao Tsuji et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)

Review Respiratory System

Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema

Ingel K. Demedts et al.

RESPIRATORY RESEARCH (2006)

Article Biochemistry & Molecular Biology

Cell-cell communication in heterocellular cultures of alveolar epithelial cells

BE Isakson et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2003)