4.8 Review

Cyclen-based artificial nucleases: Three decades of development (1989-2022). Part a - Hydrolysis of phosphate esters

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Pharmacology & Pharmacy

A Comprehensive Review on Fused Heterocyclic as DNA Intercalators: Promising Anticancer Agents

Vikas Sharma et al.

Summary: This review summarizes small organic molecules that bind to DNA through intercalation and cleaving to exert anti-tumor activity, with a focus on the structure-activity relationships, cytotoxicity data, binding data and future perspectives of medicinal compounds. The advancement in spectroscopic techniques studying DNA interactions provides valuable insights into structure-activity relationships. The introduction of fused heterocyclic agents with DNA interacting features from a medicinal standpoint is discussed in detail in this comprehensive review.

CURRENT PHARMACEUTICAL DESIGN (2021)

Editorial Material Chemistry, Physical

Molecular Recognition

Tiddo Jonathan Mooibroek et al.

CHEMPHYSCHEM (2021)

Article Chemistry, Multidisciplinary

Mercury 4.0: from visualization to analysis, design and prediction

Clare F. Macrae et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2020)

Article Chemistry, Inorganic & Nuclear

Chelators and metal complex stability for radiopharmaceutical applications

Nkemakonam C. Okoye et al.

RADIOCHIMICA ACTA (2019)

Review Chemistry, Multidisciplinary

Manipulating extracellular tumour pH: an effective target for cancer therapy

Guanyu Hao et al.

RSC ADVANCES (2018)

Review Chemistry, Medicinal

1,8-Naphthalimide based DNA intercalators and anticancer agents. A systematic review from 2007 to 2017

Mateusz D. Tomczyk et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)

Article Chemistry, Physical

[(H2O) Zn(Imidazole)n]2+: the vital roles of coordination number and geometry in Zn-OH2 acidity and catalytic hydrolysis

Douglas P. Linder et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2018)

Article Multidisciplinary Sciences

Systems analysis of intracellular pH vulnerabilities for cancer therapy

Erez Persi et al.

NATURE COMMUNICATIONS (2018)

Article Chemistry, Multidisciplinary

Update on Phosphate and Charged Post-Translationally Modified Amino Acid Parameters in the GROMOS Force Field

Christian Margreitter et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2017)

Article Biochemistry & Molecular Biology

Zinc complex of tryptophan appended 1,4,7,10-tetraazacyclododecane as potential anticancer agent: Synthesis and evaluation

Anupriya Adhikari et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2017)

Article Chemistry, Inorganic & Nuclear

A Bisamide Derivative of [Mn(1,4-DO2A)] - Solution Thermodynamic, Kinetic, and NMR Relaxometric Studies

Attila Forgacs et al.

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (2016)

Article Chemistry, Inorganic & Nuclear

Cleavage of short oligoribonucleotides by a Zn2+ binding multi-nucleating azacrown conjugate

Maarit Laine et al.

INORGANICA CHIMICA ACTA (2016)

Article Chemistry, Inorganic & Nuclear

Phosphate Diester Cleavage, DNA Interaction and Cytotoxic Activity of a Bimetallic Bis(1,4,7-triazacyclononane) Zinc Complex

Diego Montagner et al.

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (2014)

Review Pathology

Illustrating the interplay between the extracellular matrix and microRNAs

Anna M. Piccinini et al.

INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2014)

Article Biochemistry & Molecular Biology

Ligand effect and cooperative role of metal ions on the DNA cleavage efficiency of mono and binuclear Cu(II) macrocyclic ligands complexes

Nataraj Chitrapriya et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2014)

Article Chemistry, Inorganic & Nuclear

Synthesis, Characterization, and Activity of Cyclotriphosphazene-Cyclene Conjugates

Jin-Hui Wang et al.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS (2013)

Editorial Material Multidisciplinary Sciences

Watching DNA breath one molecule at a time

Jingyi Fei et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Chemistry, Multidisciplinary

Analysis of Enzymatic Transacylase Bronsted Studies with Application to the Ribosome

David A. Kingery et al.

ACCOUNTS OF CHEMICAL RESEARCH (2012)

Editorial Material Cell Biology

Autophagy on acid

Jonathan W. Wojtkowiak et al.

AUTOPHAGY (2012)

Article Biochemical Research Methods

Metal-Free DNA Linearized Nuclease Based on PASP-Polyamine Conjugates

Chao Li et al.

BIOCONJUGATE CHEMISTRY (2012)

Article Chemistry, Multidisciplinary

Vesicles and Micelles from Amphiphilic Zinc(II)-Cyclen Complexes as Highly Potent Promoters of Hydrolytic DNA Cleavage

Benjamin Gruber et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Review Oncology

Dysregulated pH: a perfect storm for cancer progression

Bradley A. Webb et al.

NATURE REVIEWS CANCER (2011)

Article Chemistry, Multidisciplinary

Artificial Transcription Factors which Mediate Double-Strand DNA Cleavage

Chao Li et al.

CHEMISTRY-A EUROPEAN JOURNAL (2010)

Review Biochemistry & Molecular Biology

What makes an enzyme promiscuous?

Ann Babtie et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Metal complexes of modified cyclen as catalysts for hydrolytic restriction of plasmid DNA

Joel A. Krauser et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2010)

Article Chemistry, Multidisciplinary

Catalytic hydrolysis of phosphate diester (BNPP) and plasmid DNA by mononuclear macrocyclic polyamine metal complexes

Qing Xiang Xiang et al.

CHINESE CHEMICAL LETTERS (2009)

Article Chemistry, Medicinal

Hydrolytic cleavage of DNA by urea-bridged macrocyclic polyamines

Jing Li et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Proteolytic activity of Co(III) complex of 1-oxa-4,7,10-triazacyclododecane: a new catalytic center for peptide-cleavage agents

Hye Mi Kim et al.

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Synthesis of a novel linear polymer of a macrocyclic polyamine copper (II) complex and its interaction with plasmid DNA

Yong-Zhe Xiang et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2009)

Article Chemistry, Multidisciplinary

New Macrocyclic Terbium(III) Complex for Use in RNA Footprinting Experiments

Matthew J. Belousoff et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Article Biochemistry & Molecular Biology

Synthesis, DNA binding and cleavage activities of the copper (II) complexes of estrogen-macrocyclic polyamine conjugates

Xin-Bin Yang et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Comparative Enzymology in the Alkaline Phosphatase Superfamily to Determine the Catalytic Role of an Active-Site Metal Ion

Jesse G. Zalatan et al.

JOURNAL OF MOLECULAR BIOLOGY (2008)

Article Chemistry, Multidisciplinary

Tethered Dinuclear Europium(III) Macrocyclic Catalysts for the Cleavage of RNA

Kido Nwe et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

Article Spectroscopy

Studies of interaction between a new synthesized minor-groove targeting artificial nuclease and DNA

Qiang Yin et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2007)

Article Chemistry, Medicinal

HeLa cells apoptosis induced by 1,7-dimethyl-1,4,7,10-tetraazacyclododecane

Li Yang et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)

Article Biochemistry & Molecular Biology

Chiral multinuclear macrocyclic polyamine complexes: Synthesis, characterization and their interaction with plasmid DNA

Yu-Guo Fang et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2007)

Article Chemistry, Multidisciplinary

Studies on a novel minor-groove targeting artificial nuclease: Synthesis and DNA binding behavior

Yin Qiang et al.

CHEMICAL RESEARCH IN CHINESE UNIVERSITIES (2007)

Article Chemistry, Inorganic & Nuclear

(Cyclen- and cyclam-pyridine)copper complexes:: The role of the pyridine moiety in CuII and CuI stabilisation

Sanae El Ghachtouli et al.

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

The conjugates of uracil-cyclen Zn(II) complexes: Synthesis, characterization, and their interaction with plasmid DNA

Chuan-Qin Xia et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2006)

Review Chemistry, Multidisciplinary

The catalytic mechanisms of binuclear metallohydrolases

Natasa Mitic et al.

CHEMICAL REVIEWS (2006)

Article Chemistry, Medicinal

DNA hydrolysis promoted by 1,7-dimethyl-1,4,7,10-tetraazacyclododecane

SH Wan et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)

Article Chemistry, Inorganic & Nuclear

Encapsulation of metal cations and anions within the cavity of bis(1,4,7-triazacyclononane) receptors

C Bazzicalupi et al.

DALTON TRANSACTIONS (2006)

Article Chemistry, Multidisciplinary

Tuning the properties of cyclen based lanthanide complexes for phosphodiester hydrolysis; the role of basic cofactors

Ann-Marie Fanning et al.

CHEMICAL COMMUNICATIONS (2006)

Article Biochemistry & Molecular Biology

The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism

C Jackson et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2005)

Article Biochemistry & Molecular Biology

Dinuclear macrocyclic polyamine zinc(II) complexes: Syntheses, characterization and their interaction with plasmid DNA

QX Xiang et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

A new heterobinuclear FeIIICuII complex with a single terminal FeIII-O(phenolate) bond.: Relevance to purple acid phosphatases and nucleases

M Lanznaster et al.

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

RNA hydrolysis and inhibition of translation by a Co(III)-cyclen complex

JB Delehanty et al.

Article Chemistry, Multidisciplinary

Solvent deuterium isotope effects on phosphodiester cleavage catalyzed by an extraordinarily active Zn(II) complex

MY Yang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Article Chemistry, Multidisciplinary

Guanidinium groups act as general-acid catalysts in phosphoryl transfer reactions: A two-proton inventory on a model system

AM Piatek et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

Article Chemistry, Organic

Mononuclear Co(III)-complex promoted phosphate diester hydrolysis: dependence of reactivity on the leaving group

M Padovani et al.

JOURNAL OF PHYSICAL ORGANIC CHEMISTRY (2004)

Article Chemistry, Inorganic & Nuclear

The ligand effect on the hydrolytic reactivity of Zn(II) complexes toward phosphate diesters

L Bonfá et al.

INORGANIC CHEMISTRY (2003)

Article Chemistry, Organic

Glycine-alanine conjugated macrocyclic lanthanide ion complexes as artificial ribonucleases

T Gunnlaugsson et al.

TETRAHEDRON LETTERS (2002)

Article Chemistry, Medicinal

Hydrolysis of linear DNA duplex catalyzed by Co(III) complex of cyclen attached to polystyrene

CS Jeung et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)

Article Biochemistry & Molecular Biology

Concerning two-metal cooperativity in model phosphate hydrolysis

M Leivers et al.

BIOORGANIC CHEMISTRY (2001)

Article Chemistry, Medicinal

Hydrolysis of plasmid DNA catalyzed by Co(III) complex of cyclen attached to polystyrene

CS Jeung et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)

Article Chemistry, Multidisciplinary

A new type of potent inhibitors of HIV-1 TAR RNA-Tat peptide binding by zinc(II)-macrocyclic tetraamine complexes

E Kikuta et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)

Article Biochemistry & Molecular Biology

Covalent joining of the subunits of a homodimeric type II restriction endonuclease:: Single-chain PvuII endonuclease

A Simoncsits et al.

JOURNAL OF MOLECULAR BIOLOGY (2001)

Article Biochemistry & Molecular Biology

The 1.9 Å crystal structure of the as isolated rubrerythrin from Desulfovibrio vulgaris:: some surprising results

LC Sieker et al.

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2000)

Article Chemistry, Inorganic & Nuclear

Reactivity of μ-hydroxodizinc(II) centers in enzymatic catalysis through model studies

NV Kaminskaia et al.

INORGANIC CHEMISTRY (2000)

Article Biochemistry & Molecular Biology

A revised mechanism for the alkaline phosphatase reaction involving three metal ions

B Stec et al.

JOURNAL OF MOLECULAR BIOLOGY (2000)

Article Nutrition & Dietetics

Function and mechanism of zinc metalloenzymes

KA McCall et al.

JOURNAL OF NUTRITION (2000)

Article Biochemistry & Molecular Biology

Oligonucleotide conjugates of Eu(III) tetraazamacrocycles with pendent alcohol and amide groups promote sequence-specific RNA cleavage

LY Huang et al.

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2000)

Article Chemistry, Inorganic & Nuclear

Thermodynamic and structural properties of Gd3+ complexes with functionalized macrocyclic ligands based upon 1,4,7,10-tetraazacyclododecane

A Bianchi et al.

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS (2000)