期刊
CLINICAL TRANSPLANTATION
卷 37, 期 4, 页码 -出版社
WILEY
DOI: 10.1111/ctr.14932
关键词
acuity circles policy; high-population states; LT
This study evaluated the impact of the acuity circles policy on liver transplant volumes. The results showed a significant increase in liver transplants for patients with MELD scores >= 29 and shorter wait times. Additionally, it was found that transplant centers in high-population states increased their transplant volume, while centers in nonhigh-population states utilized a higher proportion of marginal and circulatory death donors.
BackgroundThe allocation system for livers used the acuity circles (AC) beginning in 2020. In this study, we sought to evaluate the effect of the AC policy on center transplant volumes, from geographic and center practice perspectives. MethodsUsing the US national registry data between 2018 and 2022, adult liver transplantations (LTs) were separated into two eras: before AC and after AC. ResultsThe number of LT for Model for End-Stage Liver Disease (MELD) scores >= 29 have significantly increased by 10%, and waitlist times for those patients have been significantly shorter after AC. These benefits were not found in patients with MELD scores <29. The geographic distribution of transplant centers reveals that the majority of centers which increased their transplant volume (18 out of 25 centers) are located in high-population states while there are seven transplant centers in nonhigh-population states. The centers in the nonhigh-population states utilized more marginal donation after brain death (DBD) and donation after circulatory death (DCD) donors by 27% and 155%, respectively. MELD scores were significantly lower in the nonhigh-population states compared with those in the high-population states (p < .01). ConclusionAC improved the LT access for patients with MELD scores >= 29, which benefited the high-population states. However, aggressive center practices to utilize marginal DBD and DCD donors were able to increase transplant volume and lower median allocation MELD scores.
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