Somatostatin Receptor PET Imaging in Diffuse Pancreatic Neuroendocrine Tumor

Somatostatin receptor imaging findings of pancreatic neuroendocrine tumor with diffuse involvement of the pancreas are rarely reported. We present somatostatin receptor PET imaging findings in 3 cases of diffuse pancreatic neuroendocrine tumor. One case showed diffuse swelling and diffusely intense activity of the pancreas with multiple metastases in the peripancreatic lymph nodes and liver. The other 2 cases showed diffusely intense activity of the pancreas without metastasis. The pancreatic tumor extended into the duodenum in all the 3 cases. Familiarity with this rare pattern of radiotracer uptake in pancreatic neuroendocrine tumor may be helpful for the diagnosis.

Automated summary

Somatostatin receptor PET imaging findings in 3 cases of diffuse pancreatic neuroendocrine tumor are presented. One case showed diffuse swelling and diffusely intense activity of the pancreas with multiple metastases. The other 2 cases showed diffusely intense activity of the pancreas without metastasis. The pancreatic tumor extended into the duodenum in all 3 cases. Familiarity with this rare pattern of radiotracer uptake may aid in diagnosis of pancreatic neuroendocrine tumor.