☆ 4.7 Article

Harnessing bacteria for tumor therapy: Current advances and challenges

CHINESE CHEMICAL LETTERS (2024)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Pharmacology & Pharmacy

Salmonella-mediated blood-brain barrier penetration, tumor homing and tumor microenvironment regulation for enhanced chemo/bacterial glioma therapy

Ze Mi et al.

Summary: Chemotherapy is a crucial adjuvant therapy for glioma, however, its efficacy is limited by the barriers of blood-brain barrier (BBB) and blood-tumor barrier (BTB), as well as the intrinsic resistance of glioma cells. In this study, a bacteria-based drug delivery strategy was developed to overcome these limitations and achieve targeted glioma therapy. The bacteria selectively colonized the hypoxic tumor region and modulated the tumor microenvironment, enabling the delivery of doxorubicin-loaded bacterial outer membrane vesicles (OMVs/DOX) through neutrophil migration. The OMVs/DOX were selectively recognized by neutrophils, leading to enhanced tumor accumulation and increased efficacy of doxorubicin. The bacteria also silenced the P-glycoprotein expression on tumor cells, resulting in complete tumor eradication and improved survival. The bacteria were subsequently cleared by doxorubicin's antibacterial activity, minimizing the risk of infection and ensuring excellent compatibility.

ACTA PHARMACEUTICA SINICA B (2023)

添加到收藏夹

Article Chemistry, Multidisciplinary

Engineered Bacteria for Enhanced Radiotherapy against Breast Carcinoma

Pei Pan et al.

Summary: In this study, an integrated nanosystem composed of engineered bacteria and nanoparticles was developed for sensitizing radiotherapy. The system could target tumor sites and release a radiosensitizer, enhancing the effectiveness of radiotherapy.

ACS NANO (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Applying nanotechnology to boost cancer immunotherapy by promoting immunogenic cell death

Lvqin Fu et al.

Summary: Tumor immunogenic cell death (ICD) is a death mode of tumor cells that can enhance tumor immune responses. The application of nanotechnology can improve drug delivery and enhance the efficacy of immunotherapy.

CHINESE CHEMICAL LETTERS (2022)

添加到收藏夹

Article Nanoscience & Nanotechnology

Bacteria-Mediated Intracellular Click Reaction for Drug Enrichment and Selective Apoptosis of Drug-Resistant Tumor Cells

Zhiqiang Gao et al.

Summary: This study reports the enrichment of therapeutic drugs in tumor cells through intracellular click reaction with functionalized bacteria. Functionalized biocarriers, constructed by combining positively charged oligo(phenylene-vinylene)-alkyne with E. coli, can retain and enrich drug molecules inside drug-resistant tumor cells, providing a solution to overcome drug efflux and selectively induce apoptosis.

ACS APPLIED MATERIALS & INTERFACES (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Macrophage-targeted nanomedicine for chronic diseases immunotherapy

Yuejia Song et al.

Summary: This review summarizes the recent progress of macrophage-targeted nanomedicine for chronic diseases immunotherapy. The origin, polarization, and biological functions of macrophages are introduced. The disorder of macrophages in different chronic diseases is reviewed, and the pathological contributions of macrophages in representative diseases are discussed in detail. Strategies to regulate macrophages for disease immunotherapy, with a focus on bio-functional nanomaterials, are summarized. Methods for macrophage-targeting delivery nanosystems are discussed. Finally, the potential clinical translation and the development of novel macrophage-targeting nanomedicine for precise, effective, and biosafe therapy are speculated.

CHINESE CHEMICAL LETTERS (2022)

添加到收藏夹

Article Oncology

Recent advances in microbial toxin-related strategies to combat cancer

Prabodh Chander Sharma et al.

Summary: Microbial toxins have the potential to be a promising option for the treatment and management of cancer. They act on various biological targets and affect multiple cellular processes in cancer cells, including protein synthesis, cell growth, and cell cycle. These toxins are naturally derived and come from a variety of microbial species.

SEMINARS IN CANCER BIOLOGY (2022)

添加到收藏夹

Article Immunology

Timing of meningococcal vaccination with 4CMenB (Bexsero®) in children with invasive meningococcal group B (MenB) disease in England

Shamez N. Ladhani et al.

Summary: This study assessed the timeliness of vaccination in children with confirmed MenB disease after the implementation of 4CMenB vaccine. The results showed that a proportion of infants and toddlers did not receive the scheduled vaccine before developing MenB disease. Modifying the vaccination schedule to provide earlier protection could be beneficial.

VACCINE (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Ultrasound-controllable engineered bacteria for cancer immunotherapy

Mohamad H. Abedi et al.

Summary: Synthetic biology has enabled the design of strategies for bacteria-based cancer immunotherapy. This study developed ultrasound-activatable therapeutic bacteria that express anti-CTLA-4 and anti-PD-L1 nanobodies, successfully suppressing tumor growth in a clinically relevant cancer model.

NATURE COMMUNICATIONS (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Strategies to enhance drug delivery to solid tumors by harnessing the EPR effects and alternative targeting mechanisms

Yixuan Zi et al.

Summary: The article provides an overview of approaches for evaluating the Enhanced Permeability and Retention (EPR) effect in human tumors and discusses strategies for utilizing the EPR effect in cancer treatment. The article also highlights recent developments in alternative tumor-targeted delivery mechanisms and introduces preclinical models that better reflect human tumors. Additionally, the article suggests more rational applications of the EPR effect in other diseases and fields.

ADVANCED DRUG DELIVERY REVIEWS (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Smart drug delivery systems for precise cancer therapy

Xiaoyou Wang et al.

Summary: Nano-drug delivery systems play an important role in cancer treatment, but the balance between improved anticancer efficacy and reduced toxicity to normal tissues remains a challenge. Smart stimuli-responsive delivery strategies offer opportunities for advanced tumor specificity and controlled release behavior. The development of nanotechnology, material sciences, and biomedical sciences has enabled the creation of diverse and versatile smart drug delivery systems.

ACTA PHARMACEUTICA SINICA B (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Recent advances in photothermal and RNA interfering synergistic therapy

Kun Li et al.

Summary: Photothermal therapy (PTT) is a new treatment technique that has attracted worldwide attention in cancer treatment due to its excellent absorption ability, easy regulation, and biodegradability. The synergistic therapy of photothermal and RNA interfering (RNAi) has recently become a hot research topic, showing potential in enhancing the therapeutic effect against tumors.

CHINESE CHEMICAL LETTERS (2021)

添加到收藏夹

Article Engineering, Biomedical

Bacterial-based cancer therapy: An emerging toolbox for targeted drug/gene delivery

Dewu Lin et al.

Summary: Bacteria are increasingly being considered for targeted tumor therapy due to their intrinsic tumor tropism and ability to rapidly colonize in the favorable TME. Compared to other nano-strategies, tumor-targeting bacteria are largely unaffected by the tumor cells and microenvironment. Integration of live bacteria with anti-cancer drugs and nanomaterials can enhance targeted delivery and accumulation in tumors.

BIOMATERIALS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

The Use of Alternative Strategies for Enhanced Nanoparticle Delivery to Solid Tumors

Mukaddes Izci et al.

Summary: Research has shown that despite efforts to utilize the EPR effect for enhanced delivery of nanomaterials to solid tumors, the results are still poor. Furthermore, some studies question the role of the EPR effect, suggesting that nanomaterials may enter tumors through active mechanisms rather than through endothelial gaps.

CHEMICAL REVIEWS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition

Jing Gao et al.

Summary: This study highlights the combination of PD-L1 knockdown and CDK4/6 inhibition as a strategy to promote intratumoral infiltration of CTLs, trigger immune response, and efficiently suppress tumor growth.

CHINESE CHEMICAL LETTERS (2021)

添加到收藏夹

Article Engineering, Environmental

Exosome derived from mesenchymal stem cells mediates hypoxia-specific BMP2 gene delivery and enhances bone regeneration

Zhuo Liang et al.

Summary: A novel gene delivery vector was developed using a layer-by-layer self-assembly method with PEI and Exos derived from MSCs, which exhibited high transfection efficiency and low cytotoxicity to MSCs. Additionally, a hypoxia-specific expression plasmid combining hypoxia promoter RTP801 and miR877 sponge significantly increased BMP2 expression in hypoxic conditions and promoted neoangiogenesis, providing a potential method to enhance bone repair in tissue engineering.

CHEMICAL ENGINEERING JOURNAL (2021)

添加到收藏夹

Review Oncology

Gut microbiota influence tumor development and Alter interactions with the human immune system

Yanshan Ge et al.

Summary: Recent scientific advances have shown the complex relationship between the gut microbiome and cancer. Changes in gut microbiota composition can lead to immune dysregulation, promoting chronic inflammation and tumor development. Gut microorganisms and their metabolites can affect inflammation and tumorigenesis in specific organs through various axes of interaction.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Trojan Horse Salmonella Enabling Tumor Homing of Silver Nanoparticles via Neutrophil Infiltration for Synergistic Tumor Therapy and Enhanced Biosafety

Ze Mi et al.

Summary: Researchers enhanced the efficacy and biosafety of Salmonella by using silver nanoparticles, enabling tumor-targeting AgNPs to exert multiple functions in the tumor and ultimately eliminate the tumor with high biosafety.

NANO LETTERS (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Fighting Cancer with Bacteria and Their Toxins

Dragan Trivanovic et al.

Summary: Bacteria and their toxins show potential in cancer therapy, but also have limitations. Proteomics plays a crucial role in studying bacterial toxins, contributing to the development of anticancer drugs based on bacterial toxins. Bacterial extracellular vesicles, as a new application in immunotherapy, are an area of growing interest.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity

Xinzhou Wang et al.

Summary: Probiotics are beneficial microorganisms that colonize the human intestines and can change gut flora composition, which in turn enhances host immunity. By regulating gut microbiome with probiotics, it is an effective way to improve human immunity and quality of life.

MOLECULES (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Metabolic modulation of tumours with engineered bacteria for immunotherapy

Fernando P. Canale et al.

Summary: Engineered bacteria were developed to convert ammonia to l-arginine in tumors, increasing intratumoral l-arginine concentrations, T cell infiltration, and synergistic effects with PD-L1 blocking antibodies in tumor clearance. These results indicate that microbial therapies can enhance immunotherapy efficacy by modulating the tumor microenvironment.

NATURE (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Redox-responsive micelles integrating catalytic nanomedicine and selective chemotherapy for effective tumor treatment

Ronghua Jin et al.

Summary: The study successfully fabricated a multi-functional micelle for tumor-selective chemotherapy and drug resistance inhibition, leading to effective tumor treatment.

CHINESE CHEMICAL LETTERS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

The progress and perspective of strategies to improve tumor penetration of nanomedicines

Jiang Hu et al.

Summary: This article discusses the importance of tumor penetration, analyzes the barriers to tumor penetration, and discusses strategies such as modulating the tumor microenvironment to enhance tumor penetration.

CHINESE CHEMICAL LETTERS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Photoelectric Bacteria Enhance the In Situ Production of Tetrodotoxin for Antitumor Therapy

Xia-Nan Wang et al.

Summary: The study introduced an optically controlled material-assisted microbial system that enhances the synthesis of antitumor drugs at tumor sites by biosynthesizing gold nanoparticles on bacterial surface. This system has the potential to provide a promising antitumor therapy strategy with improved drug synthesis efficiency in situ.

NANO LETTERS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Polarization of Tumor-Associated Macrophages by Nanoparticle-Loaded Escherichia coli Combined with Immunogenic Cell Death for Cancer Immunotherapy

Baicheng Wei et al.

Summary: A new cancer treatment strategy has been developed, where tumor-associated macrophage polarization therapy combined with ICD induced by low-dose chemotherapy drugs can significantly enhance the efficacy of immunotherapy.

NANO LETTERS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella

Qiubin Lin et al.

Summary: Cancer metastasis is a major cause of cancer-related deaths, and there is an urgent need for more clinically effective metastasis-targeting agents. The authors demonstrate in multiple mouse models of cancer that Salmonella YB1 inhibits metastasis through a mechanism dependent on IFN-gamma and NK cells.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Emerging strategies in developing multifunctional nanomaterials for cancer nanotheranostics

Melgious Jin Yan Ang et al.

Summary: The review focuses on recent developments of advanced nanomaterials and nanotheranostics in cancer treatment, particularly in the areas of stimulus-responsive nanomaterials and nanocarriers targeting the tumor microenvironment. The review also discusses the potential cytotoxicity and future prospects of next-generation nanomaterials for clinical implementation.

ADVANCED DRUG DELIVERY REVIEWS (2021)

添加到收藏夹

Review Oncology

Nanomaterials for cancer therapy: current progress and perspectives

Zhe Cheng et al.

Summary: Nanomaterials play an important role in cancer therapy by targeting cancer cells, tumor microenvironment, and the immune system. However, despite an increasing number of studies, the approval of nano-drugs has not significantly increased, requiring further research to improve clinical translation efficiency.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth

Thuy Phan et al.

CANCER GENE THERAPY (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Metal-organic framework-based nanomaterials for biomedical applications

Shu Zhang et al.

CHINESE CHEMICAL LETTERS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Photosynthetic Tumor Oxygenation by Photosensitizer-Containing Cyanobacteria for Enhanced Photodynamic Therapy

Minfeng Huo et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Review Oncology

A review of cancer immunotherapy toxicity

Lucy Boyce Kennedy et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2020)

添加到收藏夹

Review Oncology

Targeted cancer immunotherapy with genetically engineered oncolytic Salmonella typhimurium

Yanxia Guo et al.

CANCER LETTERS (2020)

添加到收藏夹

Editorial Material Oncology

Targeting hypoxia in tumor: a new promising therapeutic strategy

Maria Carla Bosco et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)

添加到收藏夹

Article Cell Biology

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice R. Gurbatri et al.

SCIENCE TRANSLATIONAL MEDICINE (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy

Min Li et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Article Oncology

Salmonella Breaks Tumor Immune Tolerance by Downregulating Tumor Programmed Death-Ligand 1 Expression

Man-Chin Chen et al.

CANCERS (2020)

添加到收藏夹

Article Oncology

Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocells

Sharon M. Sagnella et al.

CANCER CELL (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity

Daniel S. Leventhal et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Inhibition of Tumor Progression through the Coupling of Bacterial Respiration with Tumor Metabolism

Qi-Wen Chen et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Review Immunology

Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies

Lijie Zhai et al.

FRONTIERS IN IMMUNOLOGY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

A reanalysis of nanoparticle tumor delivery using classical pharmacokinetic metrics

Lauren S. L. Price et al.

SCIENCE ADVANCES (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Extracellular vesicles for tumor targeting delivery based on five features principle

Tuying Yong et al.

JOURNAL OF CONTROLLED RELEASE (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

A tunablel-arabinose-inducible expression plasmid for the acetic acid bacterium Gluconobacter oxydans

Philipp Moritz Fricke et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Metabolic labeling of glycerophospholipids via clickable analogs derivatized at the lipid headgroup

Christelle F. Ancajas et al.

CHEMISTRY AND PHYSICS OF LIPIDS (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Recent advances in targeted nanomedicine as promising antitumor therapeutics

Siddhanth Hejmady et al.

DRUG DISCOVERY TODAY (2020)

添加到收藏夹

Article Microbiology

Development of a Plasmid Shuttle Vector System for Genetic Manipulation of Chlamydia psittaci

Kensuke Shima et al.

MSPHERE (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer

Xuan Yi et al.

SCIENCE ADVANCES (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Enhancement of tumour penetration by nanomedicines through strategies based on transport processes and barriers

Huang Yang et al.

JOURNAL OF CONTROLLED RELEASE (2020)

添加到收藏夹

Article Multidisciplinary Sciences

The synergistic tumor growth-inhibitory effect of probiotic Lactobacillus on transgenic mouse model of pancreatic cancer treated with gemcitabine

Shan-Ming Chen et al.

SCIENTIFIC REPORTS (2020)

添加到收藏夹

Review Medicine, Research & Experimental

Obligate and facultative anaerobic bacteria in targeted cancer therapy: Current strategies and clinical applications

Mateusz Drozdz et al.

LIFE SCIENCES (2020)

添加到收藏夹

Review Oncology

The Crosstalk Between Tumor-Associated Macrophages (TAMs) and Tumor Cells and the Corresponding Targeted Therapy

Zhe Ge et al.

FRONTIERS IN ONCOLOGY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Drug-internalized bacterial swimmers for magnetically manipulable tumor-targeted drug delivery

Zhichu Xiang et al.

NANOSCALE (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Zirconium metal-organic framework nanocrystal as microwave sensitizer for enhancement of tumor therapy

Yuanwen Zou et al.

CHINESE CHEMICAL LETTERS (2019)

添加到收藏夹

Article Engineering, Biomedical

Nanophotosensitizer-engineered Salmonella bacteria with hypoxia targeting and photothermal-assisted mutual bioaccumulation for solid tumor therapy

Fuming Chen et al.

BIOMATERIALS (2019)

添加到收藏夹

Review Oncology

Genetically engineered Salmonella Typhimurium: Recent advances in cancer therapy

Kang Liang et al.

CANCER LETTERS (2019)

添加到收藏夹

Article Biology

A switch in surface polymer biogenesis triggers growth-phase-dependent and antibiotic-induced bacteriolysis

Josue Flores-Kim et al.

ELIFE (2019)

添加到收藏夹

Review Oncology

Turning the Tide Against Regulatory T Cells

SeongJun Han et al.

FRONTIERS IN ONCOLOGY (2019)

添加到收藏夹

Article Chemistry, Physical

Photosensitizer-Bacteria Biohybrids Promote Photodynamic Cancer Cell Ablation and Intracellular Protein Delivery

Min Wu et al.

CHEMISTRY OF MATERIALS (2019)

添加到收藏夹

Review Oncology

Gut microbiota and cancer: How gut microbiota modulates activity, efficacy and toxicity of antitumoral therapy

Stefania Gori et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2019)

添加到收藏夹

Article Medicine, Research & Experimental

Probiotic supplementation attenuates the aggressiveness of chemically induced colorectal tumor in rats

Sandra Cristina Genaro et al.

LIFE SCIENCES (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Engineered nanomedicines with enhanced tumor penetration

Jianxun Ding et al.

NANO TODAY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nanoscale Bacteria-Enabled Autonomous Drug Delivery System (NanoBEADS) Enhances Intratumoral Transport of Nanomedicine

SeungBeum Suh et al.

ADVANCED SCIENCE (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors

Bertrand Routy et al.

SCIENCE (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bacteria-Driven Hypoxia Targeting for Combined Biotherapy and Photothermal Therapy

Wenfei Chen et al.

ACS NANO (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Quantifying the Ligand-Coated Nanoparticle Delivery to Cancer Cells in Solid Tumors

Qin Dai et al.

ACS NANO (2018)

添加到收藏夹

Article Medicine, General & Internal

Salmonella Overcomes Drug Resistance in Tumor through P-glycoprotein Downregulation

Chih-Jen Yang et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2018)

添加到收藏夹

Review Cell Biology

Macrophage plasticity, polarization, and function in health and disease

Abbas Shapouri-Moghaddam et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bacteria-Mediated Tumor Therapy Utilizing Photothermally-Controlled TNF-alpha Expression via Oral Administration

Jin-Xuan Fan et al.

NANO LETTERS (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Dual-targeted nanomedicines for enhanced tumor treatment

Yaqin Zhu et al.

NANO TODAY (2018)

添加到收藏夹

Article Multidisciplinary Sciences

The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients

Vyara Matson et al.

SCIENCE (2018)

添加到收藏夹

Article Multidisciplinary Sciences

Optically-controlled bacterial metabolite for cancer therapy

Di-Wei Zheng et al.

NATURE COMMUNICATIONS (2018)

添加到收藏夹

Article Microbiology

Bacterial Therapy of Cancer: Promises, Limitations, and Insights for Future Directions

M. Gabriela Kramer et al.

FRONTIERS IN MICROBIOLOGY (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Highly biocompatible BSA-MnO2 nanoparticles as an efficient near-infrared photothermal agent for cancer therapy

Yuzhen Wang et al.

CHINESE CHEMICAL LETTERS (2018)

添加到收藏夹

Review Oncology

Tumour-targeting bacteria engineered to fight cancer

Shibin Zhou et al.

NATURE REVIEWS CANCER (2018)

添加到收藏夹

Article Oncology

Application of genetically engineered Salmonella typhimurium for interferon-gamma-induced therapy against melanoma

Wonsuck Yoon et al.

EUROPEAN JOURNAL OF CANCER (2017)

添加到收藏夹

Article Medicine, General & Internal

The inhibition of indoleamine 2, 3-dioxygenase 1 by connexin 43

Han-Chen Lin et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2017)

添加到收藏夹

Article Microbiology

Outer Membrane Permeability of Cyanobacterium Synechocystis sp Strain PCC 6803: Studies of Passive Diffusion of Small Organic Nutrients Reveal the Absence of Classical Porins and Intrinsically Low Permeability

Hikaru Kowata et al.

JOURNAL OF BACTERIOLOGY (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Doxorubicin-conjugated Escherichia coli Nissle 1917 swimmers to achieve tumor targeting and responsive drug release

Songzhi Xie et al.

JOURNAL OF CONTROLLED RELEASE (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Autonomous bacterial nanoswimmers target cancer

Nour Zoaby et al.

JOURNAL OF CONTROLLED RELEASE (2017)

添加到收藏夹

Article Nanoscience & Nanotechnology

Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

Jingwei Xue et al.

NATURE NANOTECHNOLOGY (2017)

添加到收藏夹

Article Cell Biology

Two-step enhanced cancer immunotherapy with engineered Salmonella typhimurium secreting heterologous flagellin

Jin Hai Zheng et al.

SCIENCE TRANSLATIONAL MEDICINE (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Bacterial outer membrane vesicles suppress tumor by interferon-γ- mediated antitumor response

Oh Youn Kim et al.

NATURE COMMUNICATIONS (2017)

添加到收藏夹

Article Medicine, Research & Experimental

Modulation of Salmonella Tumor-Colonization and Intratumoral Anti-angiogenesis by Triptolide and Its Mechanism

Jianxiang Chen et al.

THERANOSTICS (2017)

添加到收藏夹

Review Engineering, Biomedical

Nanomaterials for cancer immunotherapy

Wantong Song et al.

BIOMATERIALS (2017)

添加到收藏夹

Review Radiology, Nuclear Medicine & Medical Imaging

Salmonella-Mediated Cancer Therapy: Roles and Potential

Vu Hong Nguyen et al.

NUCLEAR MEDICINE AND MOLECULAR IMAGING (2017)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Chemically modified surface functional groups of Alcaligenes sp S-XJ-1 to enhance its demulsifying capability

Yuyan Zhang et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2017)

添加到收藏夹

Article Oncology

Salmonella overcomes tumor immune tolerance by inhibition of tumor indoleamine 2, 3-dioxygenase 1 expression

Yu-Diao Kuan et al.

ONCOTARGET (2016)

添加到收藏夹

Review Chemistry, Multidisciplinary

Cu-Catalyzed Click Reaction in Carbohydrate Chemistry

Vinod K. Tiwari et al.

CHEMICAL REVIEWS (2016)

添加到收藏夹

Article Chemistry, Medicinal

Evaluation of the Intestinal Colonizing Potential and Immunomodulating Capacity of Lactobacilli Microspheres

Karyn I. Cotta et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Salmonella typhimurium-induced M1 macrophage polarization is dependent on the bacterial O antigen

Fengling Luo et al.

WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins

Sylwia D. Tyrkalska et al.

NATURE COMMUNICATIONS (2016)

添加到收藏夹

Article Multidisciplinary Sciences

A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours

Regino Mercado-Lubo et al.

NATURE COMMUNICATIONS (2016)

添加到收藏夹

Article Oncology

Salmonella inhibits tumor angiogenesis by downregulation of vascular endothelial growth factor

Dom-Gene Tu et al.

ONCOTARGET (2016)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Angiogenic inhibitors delivered by the type III secretion system of tumor-targeting Salmonella typhimurium safely shrink tumors in mice

Lei Shi et al.

AMB EXPRESS (2016)

添加到收藏夹

Article Microbiology

Use of Ensure® nutrition shakes as an alternative formulation method for live recombinant Attenuated Salmonella Typhi vaccines

Karen E. Brenneman et al.

BMC MICROBIOLOGY (2015)

添加到收藏夹

Review Biology

Plasticity of neutrophils reveals modulatory capacity

S. M. Perobelli et al.

BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Trg-deficient Salmonella colonize quiescent tumor regions by exclusively penetrating or proliferating

Miaomin Zhang et al.

JOURNAL OF CONTROLLED RELEASE (2015)

添加到收藏夹

Review Immunology

How bacterial pathogens colonize their hosts and invade deeper tissues

David Ribet et al.

MICROBES AND INFECTION (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Engineering Nanoparticle-Coated Bacteria as Oral DNA Vaccines for Cancer Immunotherapy

Qinglian Hu et al.

NANO LETTERS (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

Ayelet Sivan et al.

SCIENCE (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

Connexin 43 Suppresses Tumor Angiogenesis by Down-Regulation of Vascular Endothelial Growth Factor via Hypoxic-Induced Factor-1α

Wei-Kuang Wang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Improved cytotoxic effects of Salmonella-producing cytosine deaminase in tumour cells

Beatriz Mesa-Pereira et al.

MICROBIAL BIOTECHNOLOGY (2015)

添加到收藏夹

Review Immunology

Immune modulation by bacterial outer membrane vesicles

Maria Kaparakis-Liaskos et al.

NATURE REVIEWS IMMUNOLOGY (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

Salmonella induce autophagy in melanoma by the downregulation of AKT/mTOR pathway

C-H Lee et al.

GENE THERAPY (2014)

添加到收藏夹

Editorial Material Oncology

Attenuated Listeria monocytogenes reprograms M2-polarized tumor-associated macrophages in ovarian cancer leading to iNOS-mediated tumor cell lysis

Patrick H. Lizotte et al.

ONCOIMMUNOLOGY (2014)

添加到收藏夹

Article Hematology

Salmonella engineered to express CD20-targeting antibodies and a drug-converting enzyme can eradicate human lymphomas

Paul E. Massa et al.

BLOOD (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Nontoxic radioactive Listeriaat is a highly effective therapy against metastatic pancreatic cancer

Wilber Quispe-Tintaya et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

添加到收藏夹

Article Immunology

Intratumoral injection of attenuated Salmonella vaccine can induce tumor microenvironmental shift from immune suppressive to immunogenic

Eun-Hye Hong et al.

VACCINE (2013)

添加到收藏夹

Review Immunology

Cross presentation of antigen by dendritic cells: mechanisms and implications for immunotherapy

Patty Sachamitr et al.

EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2012)

添加到收藏夹

Article Cell Biology

Motility is critical for effective distribution and accumulation of bacteria in tumor tissue

Bhushan J. Toley et al.

INTEGRATIVE BIOLOGY (2012)

添加到收藏夹

Article Biotechnology & Applied Microbiology

In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis

S. Ganai et al.

CANCER GENE THERAPY (2011)

添加到收藏夹

Article Cell Biology

Bacteria-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity

Fabiana Saccheri et al.

SCIENCE TRANSLATIONAL MEDICINE (2010)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Synergistic antitumor efficacy of suicide/ePNP gene and 6-methylpurine 2'-deoxyriboside via Salmonella against murine tumors

W. Fu et al.

CANCER GENE THERAPY (2008)

添加到收藏夹

Article Oncology

Containment of tumor-colonizing bacteria by host neutrophils

Kathrin Westphal et al.

CANCER RESEARCH (2008)

添加到收藏夹

Article Oncology

Suicide gene/prodrug therapy using salmonella-mediated delivery of Escherichia coli purine nucleoside phosphorylase gene and 6-methoxypurine 2′-deoxyriboside in murine mammary carcinoma 4T1 model

Wei Fu et al.

CANCER SCIENCE (2008)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Applications of photosynthetic bacteria for medical fields

K Sasaki et al.

JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2005)

添加到收藏夹

Article Immunology

Activation of murine dendritic cells and macrophages induced by Salmonella enterica serovar Typhimurium

RS Kalupahana et al.

IMMUNOLOGY (2005)

添加到收藏夹

Review Pharmacology & Pharmacy

Controlling the kinetics of transgene expression by plasmid design

NS Yew

ADVANCED DRUG DELIVERY REVIEWS (2005)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.