期刊
CHEMISTRY OF HETEROCYCLIC COMPOUNDS
卷 59, 期 1-2, 页码 101-104出版社
SPRINGER
DOI: 10.1007/s10593-023-03168-0
关键词
imides; nitroacetic esters; oxazinones; condensation
A simple procedure was developed to synthesize 2H-pyrido[3,4-c][1,2]benzoxazine-2,4(3H)-diones from o-fluorophenyl-substituted 6-oxo-6H-1,2-oxazine-3-carboxylates using primary amines. The reaction followed a previously described mechanism for the formation of 3-(hydroxyimino)pyridine-2,6-diones, followed by intramolecular nucleophilic substitution to form the 1,2-oxazine ring.
A simple procedure was developed for the synthesis of 2H-pyrido[3,4-c][1,2]benzoxazine-2,4(3H)-diones by the treatment of o-fluorophenyl-substituted 6-oxo-6H-1,2-oxazine-3-carboxylates with primary amines. The reaction proceeded according to the mechanism previously described for the formation of 3-(hydroxyimino)pyridine-2,6-diones followed by intramolecular nucleophilic substitution involving the hydroxyimino group to form the 1,2-oxazine ring.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据