4.6 Article

From Three- to Six-Membered Heterocycles Bearing a Quaternary Stereocenter: an Asymmetric Organocatalytic Approach

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Chemistry, Organic

Progress in (Thio)urea- and Squaramide-Based Bronsted Base Catalysts with Multiple H-Bond Donors

Silvia Vera et al.

Summary: Thiourea- and squaramide-based bifunctional base catalysts have become a powerful tool for enantioselective transformations in asymmetric catalysis. Recent developments have focused on incorporating additional H-bond donor sites into the catalyst structure, resulting in more active and selective catalysts. This review presents the pioneering ideas and recent contributions to the field, organized according to the nature of the additional H-bond donor functionality, and discusses the advantages, limitations, and prospects of these new multifunctional catalysts.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2023)

Review Biochemistry & Molecular Biology

Recent advances in the biosynthesis strategies of nitrogen heterocyclic natural products

Bo Gao et al.

Summary: Nitrogen heterocyclic natural products (NHNPs), consisting of compounds with nitrogen heterocyclic skeletons, exhibit various bioactivities and find wide applications in medicines, pesticides, and food additives. Despite the low content of NHNPs in native organisms, biotechnology offers new options for their production.

NATURAL PRODUCT REPORTS (2022)

Review Chemistry, Organic

Visible light photocatalysis in the synthesis of pharmaceutically relevant heterocyclic scaffolds

Vishal Srivastava et al.

Summary: Visible light and photoredox catalysis have become powerful and long-lasting tools in organic synthesis, with significant impact on the functionalization and synthesis of heterocyclic compounds of medicinal importance.

ORGANIC CHEMISTRY FRONTIERS (2022)

Article Chemistry, Multidisciplinary

syn-Selective Epoxidation of Chiral Terminal Allylic Alcohols with a Titanium Salalen Catalyst and Hydrogen Peroxide

Fabian Severin et al.

Summary: In this study, we report a highly syn-selective epoxidation method for terminal allylic alcohols using a titanium salalen complex catalyst at room temperature and aqueous hydrogen peroxide as oxidant. The results demonstrate that enantiopure terminal allylic alcohols can be efficiently converted to epoxy alcohols with high yields and excellent syn-diastereoselectivity. This method shows great synthetic potential and is demonstrated by the gram-scale preparation of a tetrahydrofuran building block with three stereocenters.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Review Biotechnology & Applied Microbiology

Biological activity of oxadiazole and thiadiazole derivatives

Upare Abhay Atmaram et al.

Summary: This review focuses on the pharmacological properties and structural modifications of the 5-membered heterocycles oxadiazole and thiadiazole, with a particular emphasis on the anti-tubercular and anticancer activities. These heterocycles exhibit important bioisosterism and can serve as replacements in drug design.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2022)

Article Chemistry, Medicinal

Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity

Preshendren Govender et al.

Summary: The study found that new spiropyrimidinetriones (SPTs) compounds have high inhibitory potency against drug-resistant Mycobacterium tuberculosis and may have potential therapeutic value for drug-resistant tuberculosis. These compounds exert antimicrobial effects by stabilizing double-cleaved DNA of the DNA gyrase and show high selectivity against drug-resistant tuberculosis bacteria.

JOURNAL OF MEDICINAL CHEMISTRY (2022)

Review Chemistry, Multidisciplinary

Epoxides: Small Rings to Play with under Asymmetric Organocatalysis

Sara Meninno et al.

Summary: Optically pure epoxides are valuable products and key intermediates, useful in various fields such as pharmaceuticals, agrochemicals, natural product synthesis, and materials science. The predictable ring-opening process allows for selective installation of functional groups at desired carbon atoms. Asymmetric organocatalysis has provided a convenient tool for the preparation and elaboration of these compounds.

ACS ORGANIC & INORGANIC AU (2022)

Review Biochemistry & Molecular Biology

Marine natural products

Anthony R. Carroll et al.

Summary: This review summarizes the literature on marine natural products (MNPs) published in 2020, covering a wide range of compounds isolated from various marine organisms. The focus is on new compounds discovered in 2020, including their biological activities, source organisms, and country of origin. The review also includes a meta analysis of bioactivity data for new MNPs reported in the past five years.

NATURAL PRODUCT REPORTS (2022)

Article Multidisciplinary Sciences

Quaternary-centre-guided synthesis of complex polycyclic terpenes

Pengfei Hu et al.

NATURE (2019)

Review Chemistry, Multidisciplinary

Advances in One-Pot Synthesis through Borrowing Hydrogen Catalysis

Avelino Corma et al.

CHEMICAL REVIEWS (2018)

Review Chemistry, Multidisciplinary

New development in the enantioselective synthesis of spiro compounds

Aishun Ding et al.

CHEMICAL SOCIETY REVIEWS (2018)

Article Chemistry, Organic

Diastereoselective Radical Couplings Enable the Asymmetric Synthesis of anti--Amino--hydroxy Carboxylic Acid Derivatives

Denisa Hidasova et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2018)

Article Multidisciplinary Sciences

Ketamine blocks bursting in the lateral habenula to rapidly relieve depression

Yan Yang et al.

NATURE (2018)

Review Chemistry, Multidisciplinary

Catalytic Asymmetric Synthesis of Butenolides and Butyrolactones

Bin Mao et al.

CHEMICAL REVIEWS (2017)

Review Chemistry, Multidisciplinary

Asymmetric cycloaddition reactions catalysed by diarylprolinol silyl ethers

Lydia Klier et al.

CHEMICAL SOCIETY REVIEWS (2017)

Review Chemistry, Multidisciplinary

Synthetic Strategies toward Natural Products Containing Contiguous Stereogenic Quaternary Carbon Atoms

Martin Bueschleb et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Review Chemistry, Medicinal

Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry

Minghao Feng et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2016)

Article Chemistry, Multidisciplinary

Pot economy and one-pot synthesis

Yujiro Hayashi

CHEMICAL SCIENCE (2016)

Review Chemistry, Organic

Total syntheses of natural products containing spirocarbocycles

Laura K. Smith et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2015)

Article Chemistry, Inorganic & Nuclear

Applications of Sharp less asymmetric epoxidation in total synthesis

Majid M. Heravi et al.

TETRAHEDRON-ASYMMETRY (2015)

Article Chemistry, Organic

Iron(II)-Catalyzed Asymmetric Epoxidation of Trisubstituted alpha,beta-Unsaturated Esters

Lan Luo et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2014)

Article Chemistry, Medicinal

A New Avenue toward Androgen Receptor Pan-antagonists: C2 Sterically Hindered Substitution of Hydroxy-propanamides

Andrea Guerrini et al.

JOURNAL OF MEDICINAL CHEMISTRY (2014)

Review Multidisciplinary Sciences

Catalytic enantioselective synthesis of quaternary carbon stereocentres

Kyle W. Quasdorf et al.

NATURE (2014)

Article Behavioral Sciences

R(-)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine

Ji-chun Zhang et al.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2014)

Letter Neurosciences

The R-Stereoisomer of Ketamine as an Alternative for Ketamine for Treatment-resistant Major Depression

Kenji Hashimoto

CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE (2014)

Article Chemistry, Multidisciplinary

Asymmetric organocatalysis mediated by α,α-L-diaryl prolinols: recent advances

Sara Meninno et al.

CHEMICAL COMMUNICATIONS (2013)

Review Agronomy

Heterocyclic chemistry in crop protection

Clemens Lamberth

PEST MANAGEMENT SCIENCE (2013)

Article Chemistry, Applied

On the Mechanism of Asymmetric Epoxidation of Enones Catalyzed by α,α-L-Diarylprolinols: A Theoretical Insight

Amedeo Capobianco et al.

ADVANCED SYNTHESIS & CATALYSIS (2012)

Review Chemistry, Multidisciplinary

Synthetic Routes to Chiral Nonracemic and Racemic Dihydro- And Tetrahydrothiophenes

Simonetta Benetti et al.

CHEMICAL REVIEWS (2012)

Article Chemistry, Multidisciplinary

Enantioselective synthesis of all-carbon quaternary stereogenic centers in acyclic systems

Jaya Prakash Das et al.

CHEMICAL COMMUNICATIONS (2011)

Review Chemistry, Multidisciplinary

From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

Santos Fustero et al.

CHEMICAL REVIEWS (2011)

Article Multidisciplinary Sciences

Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections

Paul A. Clemons et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Chemistry, Multidisciplinary

Recent developments on chiral P,S-type ligands and their applications in asymmetric catalysis

Fuk Loi Lam et al.

CHEMICAL COMMUNICATIONS (2010)

Article Chemistry, Multidisciplinary

Catalytic Asymmetric Epoxidation of α-Branched Enals

Olga Lifchits et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Review Chemistry, Multidisciplinary

Organocatalytic cascade reactions as a new tool in total synthesis

Christoph Grondal et al.

NATURE CHEMISTRY (2010)

Review Chemistry, Multidisciplinary

Asymmetric organocatalysis by chiral Bronsted bases: implications and applications

Claudio Palomo et al.

CHEMICAL SOCIETY REVIEWS (2009)

Article Chemistry, Multidisciplinary

An Organocatalytic Asymmetric Tandem Reaction for the Construction of Bicyclic Skeletons

Chun-Li Cao et al.

CHEMISTRY-A EUROPEAN JOURNAL (2009)

Article Chemistry, Medicinal

Aminoimidazoles as Potent and Selective Human β-Secretase (BACE1) Inhibitors

Michael S. Malamas et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Article Chemistry, Medicinal

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

Frank Lovering et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Review Chemistry, Organic

Organocatalytic Formation of Quaternary Stereocenters

Marco Bella et al.

SYNTHESIS-STUTTGART (2009)

Review Chemistry, Multidisciplinary

Asymmetric catalysis with bifunctional cinchona alkaloid-based urea and thiourea organocatalysts

Stephen J. Connon

CHEMICAL COMMUNICATIONS (2008)

Article Chemistry, Multidisciplinary

Controlling the formation of 1 out of 64 stereoisomers using organocatalysis

Soren Bertelsen et al.

CHEMICAL COMMUNICATIONS (2008)

Review Chemistry, Multidisciplinary

Small-molecule H-bond donors in asymmetric catalysis

Abigail G. Doyle et al.

CHEMICAL REVIEWS (2007)

Review Chemistry, Multidisciplinary

Stronger bronsted acids

Takahiko Akiyama

CHEMICAL REVIEWS (2007)

Article Chemistry, Organic

Enantioselective organocatalytic double Michael addition reactions

Hao Li et al.

ORGANIC LETTERS (2007)

Review Chemistry, Multidisciplinary

Recent advances in asymmetric phase-transfer catalysis

Takashi Ooi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Article Chemistry, Multidisciplinary

Asymmetric epoxidation of terminal alkenes with hydrogen peroxide catalyzed by pentafluorophenyl PtII complexes

Marco Colladon et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Review Medicine, Research & Experimental

Hyperforin:: More than an antidepressant bioactive compound?

Miguel A. Medina et al.

LIFE SCIENCES (2006)

Review Chemistry, Organic

Cyclic oxonitriles: Synergistic juxtaposition of ketone and nitrile functionalities

FF Fleming et al.

SYNTHESIS-STUTTGART (2006)

Review Chemistry, Organic

Catalytic enantioselective construction of all-carbon quaternary stereocenters

BM Trost et al.

SYNTHESIS-STUTTGART (2006)

Article Chemistry, Multidisciplinary

Catalytic asymmetric epoxidation of α,β-unsaturated esters using an yttrium-biphenyidiol complex

H Kakei et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Review Chemistry, Multidisciplinary

Advances in homogeneous and heterogeneous catalytic asymmetric epoxidation

QH Xia et al.

CHEMICAL REVIEWS (2005)

Review Chemistry, Multidisciplinary

Chromium- and manganese-salen promoted epoxidation of alkenes

EM McGarrigle et al.

CHEMICAL REVIEWS (2005)

Review Chemistry, Organic

Asymmetric organocatalysis

J Seayad et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2005)

Article Chemistry, Multidisciplinary

Enantioselective Michael reaction of malonates to nitroolefins catalyzed by bifunctional organocatalysts

T Okino et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)

Review Chemistry, Multidisciplinary

Enantioselective synthesis of paraconic acids

RB Chhor et al.

CHEMISTRY-A EUROPEAN JOURNAL (2003)

Article Chemistry, Organic

Total synthesis of luminacin D

JB Shotwell et al.

ORGANIC LETTERS (2002)

Article Chemistry, Multidisciplinary

Highly enantioselective epoxidation of α,β-unsaturated esters by chiral dioxirane

XY Wu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

Review Chemistry, Multidisciplinary

Design of folded peptides

J Venkatraman et al.

CHEMICAL REVIEWS (2001)

Article Chemistry, Organic

Enantioselective epoxidation of terminal olefins by chiral dioxirane

HQ Tian et al.

ORGANIC LETTERS (2001)