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Gene expression analysis of rheumatoid arthritis synovial lining regions by cDNA microarray combined with laser microdissection: up-regulation of inflammation-associated STAT1, IRF1, CXCL9, CXCL10, and CCL5
S. Yoshida et al.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2012)
Maraviroc, a chemokine receptor-5 antagonist, fails to demonstrate efficacy in the treatment of patients with rheumatoid arthritis in a randomized, double-blind placebo-controlled trial
Dona L. Fleishaker et al.
ARTHRITIS RESEARCH & THERAPY (2012)
Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4
Dong Hyun Sohn et al.
ARTHRITIS RESEARCH & THERAPY (2012)
Bone Loss in Rheumatoid Arthritis: Systemic, Periarticular, and Focal
Chad Deal
CURRENT RHEUMATOLOGY REPORTS (2012)
Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
Kirk R. Henne et al.
DRUG METABOLISM AND DISPOSITION (2012)
A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial)
Pierre Quartier et al.
ANNALS OF THE RHEUMATIC DISEASES (2011)
The Assessment of SpondyloArthritis international Society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general
M. Rudwaleit et al.
ANNALS OF THE RHEUMATIC DISEASES (2011)
Coexpression of Chemokine Receptors CCR5, CXCR3, and CCR4 and Ligands for P- and E-Selectin on T Lymphocytes of Patients With Juvenile Idiopathic Arthritis
Andrew C. Issekutz et al.
ARTHRITIS AND RHEUMATISM (2011)
Identification of CXCL13 as a Marker for Rheumatoid Arthritis Outcome Using an In Silico Model of the Rheumatic Joint
Cees M. Meeuwisse et al.
ARTHRITIS AND RHEUMATISM (2011)
Synovial Fibroblast Hyperplasia in Rheumatoid Arthritis Clinicopathologic Correlations and Partial Reversal by Anti-Tumor Necrosis Factor Therapy
Elena Izquierdo et al.
ARTHRITIS AND RHEUMATISM (2011)
Local Expression of Interleukin-27 Ameliorates Collagen-Induced Arthritis
Sarah R. Pickens et al.
ARTHRITIS AND RHEUMATISM (2011)
III. Identification of novel CXCR3 chemokine receptor antagonists with a pyrazinyl-piperazinyl-piperidine scaffold
Seong Heon Kim et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3
Sofie Struyf et al.
BLOOD (2011)
How I treat hemophagocytic lymphohistiocytosis
Michael B. Jordan et al.
BLOOD (2011)
Chemokines as mediators of tumor angiogenesis and neovascularization
Ellen C. Keeley et al.
EXPERIMENTAL CELL RESEARCH (2011)
Effect of posttranslational processing on the in vitro and in vivo activity of chemokines
Anneleen Mortier et al.
EXPERIMENTAL CELL RESEARCH (2011)
Expression and agonist responsiveness of CXCR3 variants in human T lymphocytes
Anna Korniejewska et al.
IMMUNOLOGY (2011)
Inflammatory Musculoskeletal Disease: Identification and Assessment
PHILIP J. MEASE
JOURNAL OF RHEUMATOLOGY (2011)
Juvenile idiopathic arthritis
Berent Prakken et al.
LANCET (2011)
Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions
Elizabeth D. Mellins et al.
NATURE REVIEWS RHEUMATOLOGY (2011)
Potential role and mechanism of IFN-gamma inducible protein-10 on receptor activator of nuclear factor kappa-B ligand (RANKL) expression in rheumatoid arthritis
Eun Young Lee et al.
ARTHRITIS RESEARCH & THERAPY (2011)
Overcoming hurdles in developing successful drugs targeting chemokine receptors
Thomas J. Schall et al.
NATURE REVIEWS IMMUNOLOGY (2011)
TWEAK and its receptor Fn14 in the synovium of patients with rheumatoid arthritis compared to psoriatic arthritis and its response to tumour necrosis factor blockade
A. W. R. van Kuijk et al.
ANNALS OF THE RHEUMATIC DISEASES (2010)
Deficiency of CXCR2, but Not Other Chemokine Receptors, Attenuates Autoantibody-Mediated Arthritis in a Murine Model
Jonathan P. Jacobs et al.
ARTHRITIS AND RHEUMATISM (2010)
Synovial Tissue-Infiltrating Natural Killer Cells in Osteoarthritis and Periprosthetic Inflammation
Ryan S. Huss et al.
ARTHRITIS AND RHEUMATISM (2010)
Up-Regulation of Cytokines and Chemokines Predates the Onset of Rheumatoid Arthritis
Heidi Kokkonen et al.
ARTHRITIS AND RHEUMATISM (2010)
Biologic Predictors of Extension of Oligoarticular Juvenile Idiopathic Arthritis as Determined From Synovial Fluid Cellular Composition and Gene Expression
Patricia J. Hunter et al.
ARTHRITIS AND RHEUMATISM (2010)
Pathogenic Role of CXCR7 in Rheumatoid Arthritis
Kaori Watanabe et al.
ARTHRITIS AND RHEUMATISM (2010)
The Role of Synovial Macrophages and Macrophage-Produced Mediators in Driving Inflammatory and Destructive Responses in Osteoarthritis
Jan Bondeson et al.
ARTHRITIS AND RHEUMATISM (2010)
Discovery of a novel series of CXCR3 antagonists
Stefano Crosignani et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis
P. H. Schafer et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Synovial fluid cells in juvenile arthritis: evidence of selective T cell migration to inflamed tissue
E. D. SILVERMAN et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
Gene modulation and immunoregulatory roles of Interferonγ
Banishree Saha et al.
CYTOKINE (2010)
A Randomized, Placebo-Controlled Trial of MDX-1100, an Anti-IP-10 Antibody, for Moderately to Severely Active Ulcerative Colitis
Lloyd Mayer et al.
GASTROENTEROLOGY (2010)
Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis
Beatrix Bartok et al.
IMMUNOLOGICAL REVIEWS (2010)
Characterization of the Chemokine CXCL11-Heparin Interaction Suggests Two Different Affinities for Glycosaminoglycans
India C. Severin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4
Dianhua Jiang et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
CXCL 9 and CXCL 10 as Sensitive Markers of Disease Activity in Patients with Rheumatoid Arthritis
Woon Pang Kuan et al.
JOURNAL OF RHEUMATOLOGY (2010)
Chemokine profile of synovial fluid from normal, osteoarthritis and rheumatoid arthritis patients: CCL25, CXCL10 and XCL1 recruit human subchondral mesenchymal progenitor cells
M. Endres et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
CXCL10 Can Inhibit Endothelial Cell Proliferation Independently of CXCR3
Gabriele S. V. Campanella et al.
PLOS ONE (2010)
Etanercept treatment reduces the serum levels of interleukin-15 and interferon-gamma inducible protein-10 in patients with rheumatoid arthritis
Tetsuya Ichikawa et al.
RHEUMATOLOGY INTERNATIONAL (2010)
Defective Phosphorylation of Interleukin-18 Receptor β Causes Impaired Natural Killer Cell Function in Systemic-Onset Juvenile Idiopathic Arthritis
Wilco de Jager et al.
ARTHRITIS AND RHEUMATISM (2009)
Systemic JIA: new developments in the understanding of the pathophysiology and therapy
Sebastiaan J. Vastert et al.
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2009)
Optimization of a series of quinazolinone-derived antagonists of CXCR3
Jiwen Liu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Imidazo-pyrazine derivatives as potent CXCR3 antagonists
Xiaohui Du et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
The chemokine receptor antagonist, TAK-779, decreased experimental autoimmune encephalomyelitis by reducing inflammatory cell migration into the central nervous system, without affecting T cell function
Jia Ni et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
CXCL10 Impairs β Cell Function and Viability in Diabetes through TLR4 Signaling
Fabienne T. Schulthess et al.
CELL METABOLISM (2009)
Neutralization of IFNγ defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice
Jana Pachlopnik Schmid et al.
EMBO MOLECULAR MEDICINE (2009)
Essential Involvement of Cross-Talk Between IFN-γ and TNF-α in CXCL10 Production in Human THP-1 Monocytes
Xu-Feng Qi et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
CXCR3 Mediates Renal Th1 and Th17 Immune Response in Murine Lupus Nephritis
Oliver M. Steinmetz et al.
JOURNAL OF IMMUNOLOGY (2009)
Role of Double-Stranded RNA Pattern Recognition Receptors in Rhinovirus-Induced Airway Epithelial Cell Responses
Qiong Wang et al.
JOURNAL OF IMMUNOLOGY (2009)
Elucidation of Binding Sites of Dual Antagonists in the Human Chemokine Receptors CCR2 and CCR5
Spencer E. Hall et al.
MOLECULAR PHARMACOLOGY (2009)
The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity
Monika Pruenster et al.
NATURE IMMUNOLOGY (2009)
Chemokine Receptor Blockade With a Synthetic Nonpeptide Compound Attenuates Cardiac Allograft Vasculopathy
Sam Bastani et al.
TRANSPLANTATION (2009)
Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis
Anna Corcione et al.
ARTHRITIS RESEARCH & THERAPY (2009)
Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis
Toshihiro Nanki et al.
ARTHRITIS RESEARCH & THERAPY (2009)
Reliability of tumor markers, chemokines, and metastasis-related molecules in serum
Faina Linkov et al.
EUROPEAN CYTOKINE NETWORK (2009)
Duffy antigen receptor for chemokines and CXCL5 are essential for the recruitment of neutrophils in a multicellular model of rheumatoid arthritis synovium
Emily Smith et al.
ARTHRITIS AND RHEUMATISM (2008)
The arthritis severity locus Cia5d is a novel genetic regulator of the invasive properties of synovial fibroblasts
Teresina Laragione et al.
ARTHRITIS AND RHEUMATISM (2008)
Reciprocal cross-talk between RANKL and interferon-γ-inducible protein 10 is responsible for bone-erosive experimental arthritis
Han Bok Kwak et al.
ARTHRITIS AND RHEUMATISM (2008)
The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis
Marco Gattorno et al.
ARTHRITIS AND RHEUMATISM (2008)
High values of alpha (CXCL10) and beta (CCL2) circulating chemokines in patients with psoriatic arthritis, in presence or absence of autoimmune thyroiditis
Alessandro Antonelli et al.
AUTOIMMUNITY (2008)
Discovery of small molecule benzimidazole antagonists of the chemokine receptor CXCR3
Martin E. Hayes et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation
Tamara Loos et al.
BLOOD (2008)
Towards small-molecule CXCR3 ligands with clinical potential
Maikel Wijtmans et al.
CHEMMEDCHEM (2008)
Stromal cell-derived factors 1α and 1β, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8
Katerina Ajami et al.
FEBS LETTERS (2008)
Infiltrated Neutrophils Acquire Novel Chemokine Receptor Expression and Chemokine Responsiveness in Chronic Inflammatory Lung Diseases
Dominik Hart et al.
JOURNAL OF IMMUNOLOGY (2008)
CXCL9 and CXCL10 expression are critical for control of genital herpes simplex virus type 2 infection through mobilization of HSV-specific CTL and NK cells to the nervous system
Manoj Thapa et al.
JOURNAL OF IMMUNOLOGY (2008)
CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3
Anja Mueller et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Regulation of chemokine activity by posttranslational modification
Anneleen Mortier et al.
PHARMACOLOGY & THERAPEUTICS (2008)
Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria
Gabriele S. V. Campanella et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cia5d regulates a new fibroblast-like synoviocyte invasion-associated gene expression signature
Teresina Laragione et al.
ARTHRITIS RESEARCH & THERAPY (2008)
Development of CXCR3 antagonists. Part 2: Identification of 2-amino(4-piperidinyl)azoles as potent CXCR3 antagonists
Robert J. Watson et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Blockade of chemokine receptor CXCR3 inhibits T cell recruitment to inflamed joints and decreases the severity of adjuvant arthritis
Karkada Mohan et al.
JOURNAL OF IMMUNOLOGY (2007)
Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome
Ndate Fall et al.
ARTHRITIS AND RHEUMATISM (2007)
Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7
Frederic Sierro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Synovial angiostatic non-ELR CXC chemokines in inflammatory arthritides: does CXCL4 designate chronicity of synovitis?
Hakan Erdem et al.
RHEUMATOLOGY INTERNATIONAL (2007)
Proteolytic processing of CXCL11 by CD13/aminopeptidase N impairs CXCR3 and CXCR7 binding and signaling and reduces lymphocyte and endothelial cell migration
Paul Proost et al.
BLOOD (2007)
Discovery and optimization of a series of quinazolinone-derived antagonists of CXCR3
Michael Johnson et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Specific gene expression profiles in systemic juvenile idiopathic arthritis
Emma Mary Ogilvie et al.
ARTHRITIS AND RHEUMATISM (2007)
Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti-citrulline autoreactivity is associated with up regulation of proinflammatory cytokines
Wolfgang Hueber et al.
ANNALS OF THE RHEUMATIC DISEASES (2007)
Chemokine and chemokine receptor analysis reveals elevated interferon-inducible protein-10 (IP)-10/CXCL10 levels and increased number of CCR5+ and CXCR3+ CD4 T cells in synovial fluid of patients with enthesitis-related arthritis (ERA)
A. Aggarwal et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2007)
Blood and synovial fluid cytokine signatures in patients with juvenile idiopathic arthritis: a cross-sectional study
Wilco de Jager et al.
ANNALS OF THE RHEUMATIC DISEASES (2007)
Inhibition of Gαi2 activation by Gαi3 in CXCR3-mediated signaling
Brian D. Thompson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor α-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis
Jack Bleesing et al.
ARTHRITIS AND RHEUMATISM (2007)
Lymphoid neogenesis in juvenile idiopathic arthritis correlates with ANA positivity and plasma cells infiltration
A. Gregorio et al.
RHEUMATOLOGY (2007)
Identification and structure-activity relationships of 1-aryl-3-piperidin-4-yl-urea derivatives as CXCR3 receptor antagonists
Daniel R. Allen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis
Reuben Gobezie et al.
ARTHRITIS RESEARCH & THERAPY (2007)
A novel CCR5/CXCR3 antagonist protects intestinal ischemia/reperfusion injury
T. Akahori et al.
TRANSPLANTATION PROCEEDINGS (2006)
Oligomerization of CXCL10 is necessary for endothelial cell presentation and in vivo activity
Gabriele S. V. Campanella et al.
JOURNAL OF IMMUNOLOGY (2006)
Identification of CXCR3 receptor agonists in combinatorial small-molecule libraries
Ilana L. Stroke et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Heparin displaces interferon-γ-inducible chemokines (IP-10, I-TAC, and Mig) sequestered in the vasculature and inhibits the transendothelial migration and arterial recruitment of T cells
Hooman Ranjbaran et al.
CIRCULATION (2006)
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development
Jennifer M. Burns et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
TLR ligands and cytokines induce CXCR3 ligands in endothelial cells: enhanced CXCL9 in autoimmune arthritis
Tamara Loos et al.
LABORATORY INVESTIGATION (2006)
A multicenter study of patients with adult-onset Still's disease compared with systemic juvenile idiopathic arthritis
Salih Pay et al.
CLINICAL RHEUMATOLOGY (2006)
Dengue virus induces expression of CXC chemokine ligand 10/IFN-γ-inducible protein 10, which competitively inhibits viral binding to cell surface heparan sulfate
Jia-Perng Chen et al.
JOURNAL OF IMMUNOLOGY (2006)
Antagonism of CXCR3 inhibits lung metastasis in a murine model of metastatic breast cancer
Tonya C. Walser et al.
CANCER RESEARCH (2006)
Preferential type 1 chemokine receptors and cytokine production of CD28- T cells in ankylosing spondylitis
C Duftner et al.
ANNALS OF THE RHEUMATIC DISEASES (2006)
Paediatric rheumatology - A global perspective
S Sawhney et al.
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2006)
CD56(bright)CD16(-) NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation
C Ottaviani et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
The chemokines CXCL9 and CXCL10 promote a protective immune response but do not contribute to cardiac inflammation following infection with Trypanosoma cruzi
JL Hardison et al.
INFECTION AND IMMUNITY (2006)
Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+T cells
Daniel S. Pharoah et al.
ARTHRITIS RESEARCH & THERAPY (2006)
Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathies
Paul Proost et al.
ARTHRITIS RESEARCH & THERAPY (2006)
Matrix metalloproteinases: Role in arthritis
PS Burrage et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2006)
CXC chemokines in angiogenesis
RM Strieter et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2005)
Synergy in cytokine and chemokine networks amplifies the inflammatory response
M Gouwy et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2005)
TAK-652 inhibits CCR5-mediated human immunodeficiency virus type 1 infection in vitro and has favorable pharmacokinetics in humans
M Baba et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Pathogenic role of the CXCL16-CXCR6 pathway in rheumatoid arthritis
T Nanki et al.
ARTHRITIS AND RHEUMATISM (2005)
TNF inhibition rapidly down-regulates multiple proinflammatory pathways in psoriasis plaques
AB Gottlieb et al.
JOURNAL OF IMMUNOLOGY (2005)
The simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis
H Tokuyama et al.
INTERNATIONAL IMMUNOLOGY (2005)
Accumulation of plasma cells expressing CXCR3 in the synovial sublining regions of early rheumatoid arthritis in association with production of Mig/CXCL9 by synovial fibroblasts
T Tsubaki et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2005)
The production of CXCR3-agonistic chemokines by synovial fibroblasts from patients with rheumatoid arthritis
A Ueno et al.
RHEUMATOLOGY INTERNATIONAL (2005)
Synthesis and structure-activity relationship of 3-phenyl-3H-quinazolin-4-one derivatives as CXCR3 chemokine receptor antagonists
S Storelli et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist
CE Heise et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
V Pascual et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis
I Tchetverikov et al.
ANNALS OF THE RHEUMATIC DISEASES (2005)
Macrophage activation syndrome:: characteristic findings on liver biopsy illustrating the key role of activated, IFN-γ-producing lymphocytes and IL-6- and TNF-α-producing macrophages
AD Billiau et al.
BLOOD (2005)
Increase of peripheral CXCR3 positive T lymphocytes upon treatment of RA patients with TNF-α inhibitors
D Aeberli et al.
RHEUMATOLOGY (2005)
Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5
C Schmutz et al.
ARTHRITIS RESEARCH & THERAPY (2005)
CXCR3/CXCL10 expression in the synovium of children with juvenile idiopathic arthritis
G Martini et al.
ARTHRITIS RESEARCH & THERAPY (2005)
Phenotypic and functional characterisation of CCR7(+) and CCR7(-) CD4(+) memory T cells homing to the joints in juvenile idiopathic arthritis
M Gattorno et al.
ARTHRITIS RESEARCH & THERAPY (2005)
Chemokine control of lymphocyte trafficking: a general overview
JV Stein et al.
IMMUNOLOGY (2005)
Furin is a chemokine-modifying enzyme -: In vitro and in vivo processing of CXCL10 generates a C-terminally truncated chemokine retaining full activity
PJ Hensbergen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Lymphadenopathy in adult-onset Still's disease mimicking peripheral T-cell lymphoma
M Soy et al.
CLINICAL RHEUMATOLOGY (2004)
Chemokines: multiple levels of leukocyte migration control
B Moser et al.
TRENDS IN IMMUNOLOGY (2004)
Spectrum of lymph node pathology in adult onset Still's disease; analysis of 12 patients with one follow up biopsy
YK Jeon et al.
JOURNAL OF CLINICAL PATHOLOGY (2004)
Predominance of Th1 cytokine in peripheral blood and pathological tissues of patients with active untreated adult onset Still's disease
DY Chen et al.
ANNALS OF THE RHEUMATIC DISEASES (2004)
I-TAC/CXCL11 is a natural antagonist for CCR5
V Petkovic et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
The human Duffy antigen binds selected inflammatory but not homeostatic chemokines
L Gardner et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Characterization and recruitment of plasmacytoid dendritic cells in synovial fluid and tissue of patients with chronic inflammatory arthritis
R Lande et al.
JOURNAL OF IMMUNOLOGY (2004)
An animal model of hemophagocytic lymphohistiocytosis (HLH):: CD8+ T cells and interferon gamma are essential for the disorder
MB Jordan et al.
BLOOD (2004)
Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands
N Kohrgruber et al.
JOURNAL OF IMMUNOLOGY (2004)
CC and CXC chemokine receptors mediate migration, proliferation, and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients
R García-Vicuña et al.
ARTHRITIS AND RHEUMATISM (2004)
Identification and partial characterization of a variant of human CXCR3 generated by posttranscriptional exon skipping
JE Ehlert et al.
JOURNAL OF IMMUNOLOGY (2004)
The inflammatory side of human chondrocytes unveiled by antibody microarrays
F De Ceuninck et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Synergistic induction of CXCL9 and CXCL11 by Toll-like receptor ligands and interferon-γ in fibroblasts correlates with elevated levels of CXCR3 ligands in septic arthritis synovial fluids
P Proost et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Among CXCR3 chemokines, IFN-γ-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-γ (CXCL9) imprints a pattern for the subsequent development of autoimmune disease
U Christen et al.
JOURNAL OF IMMUNOLOGY (2003)
A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind inflammatory, but not lymphoid, chemokines and is dispensable for lymphocyte homing under physiological conditions
M Kashiwazaki et al.
INTERNATIONAL IMMUNOLOGY (2003)
CXCR3-mediated chernotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase
MJ Smit et al.
BLOOD (2003)
Increased serum levels of interferon-γ-inducible protein 10 and monokine induced by gamma interferon in patients with haemophagocytic lymphohistiocytosis
H Takada et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2003)
CCR3 functional responses are regulated by both CXCR3 and its ligands CXCL9, CXCL10 and CXCL11
G Xanthou et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4
L Lasagni et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation
JH Xie et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2003)
Evolving concepts of rheumatoid arthritis
GS Firestein
NATURE (2003)
Chemokine/chemokine receptor nomenclature
K Bacon et al.
CYTOKINE (2003)
High CXCR3 expression in synovial mast cells associated with CXCL9 and CXCL10 expression in inflammatory synovial tissues of patients with rheumatoid arthritis
P Ruschpler et al.
ARTHRITIS RESEARCH & THERAPY (2003)
A novel mechanism for the regulation of IFN-gamma inducible protein-10 expression in rheumatoid arthritis
R Hanaoka et al.
ARTHRITIS RESEARCH & THERAPY (2003)
An association between the acute phase response and patterns of antigen induced T cell proliferation in juvenile idiopathic arthritis
APB Black et al.
ARTHRITIS RESEARCH & THERAPY (2003)
Microbial Toll-like receptor ligands differentially regulate CXCL10/IP-10 expression in fibroblasts and mononuclear leukocytes in synergy with IFN-gamma and provide a mechanism for enhanced synovial chemokine levels in septic arthritis
P Proost et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Human osteoblasts express functional CXC chemokine receptors 3 and 5: Activation by their ligands, CXCL10 and CXCL13, significantly induces alkaline phosphatase and beta-N-acetylhexosaminidase release
G Lisignoli et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2003)
Long-term follow-up of 246 adults with juvenile idiopathic arthritis: functional outcome
JC Packham et al.
RHEUMATOLOGY (2002)
Targeting the function of IFN-γ-inducible protein 10 suppresses ongoing adjuvant arthritis
I Salomon et al.
JOURNAL OF IMMUNOLOGY (2002)
Long-term outcome in patients with juvenile idiopathic arthritis
K Minden et al.
ARTHRITIS AND RHEUMATISM (2002)
A subset of natural killer cells is greatly expanded within inflamed joints
N Dalbeth et al.
ARTHRITIS AND RHEUMATISM (2002)
Expression of the Duffy antigen/receptor for chemokines (DARC) by the inflamed synovial endothelium
AM Patterson et al.
JOURNAL OF PATHOLOGY (2002)
Reduction of cytokine-induced expression and activity of MMP-1 and MMP-13 by mechanical strain in MH7A rheumatoid synovial cells
HB Sun et al.
MATRIX BIOLOGY (2002)
IFN-γ-Inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking
JH Dufour et al.
JOURNAL OF IMMUNOLOGY (2002)
Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies
Y Chicheportiche et al.
ARTHRITIS RESEARCH (2002)
CXCR3 internalization following T cell-endothelial cell contact:: Preferential role of IFN-Inducible T cell α chemoattractant (CXCL11)
A Sauty et al.
JOURNAL OF IMMUNOLOGY (2001)
Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties
P Proost et al.
BLOOD (2001)
A functional IFN-γ-inducible protein-10/CXCL10-specific receptor expressed by epithelial and endothelial cells that is neither CXCR3 nor glycosaminoglycan
K Soejima et al.
JOURNAL OF IMMUNOLOGY (2001)
Macrophage activation syndrome: a potentially fatal complication of rheumatic disorders
S Sawhney et al.
ARCHIVES OF DISEASE IN CHILDHOOD (2001)
Secretion of gelatinases and activation of gelatinase A (MMP-2) by human rheumatoid synovial fibroblasts
H Smolian et al.
BIOLOGICAL CHEMISTRY (2001)
Processing of natural and recombinant CXCR3-targeting chemokines and implications for biological activity
PJ Hensbergen et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2001)
High-resolution mapping of the human 4q21 and the mouse 5E3 SCYB chemokine cluster by fiber-fluorescence in situ hybridization
M Erdel et al.
IMMUNOGENETICS (2001)
Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family
AM Lambeir et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Cutting edge:: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity
AM Cole et al.
JOURNAL OF IMMUNOLOGY (2001)
Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire
JJ Campbell et al.
JOURNAL OF IMMUNOLOGY (2001)
Signal transduction by the chemokine receptor CXCR3 - Activation of Ras/ERK, Src, and phosphatidylinositol 3-kinase/Akt controls cell migration and proliferation in human vascular pericytes
A Bonacchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Potential role of the chemokine receptors CXCR3, CCR4, and the integrin αEβ7 in the pathogenesis of psoriasis vulgaris
JB Rottman et al.
LABORATORY INVESTIGATION (2001)
CXCR3 chemokine receptor distribution in normal and inflamed tissues:: Expression on activated lymphocytes, endothelial cells, and dendritic cells
MA García-López et al.
LABORATORY INVESTIGATION (2001)
The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3
P Loetscher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Interferon-inducible protein 10, monokine induced by interferon gamma, and interferon-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) αβ+CD8+ single-positive T cells, TCRγδ+ T cells, and natural killer-type cells in human thymus
P Romagnani et al.
BLOOD (2001)
CXCR3 and CCR5 ligands in rheumatoid arthritis synovium
DD Patel et al.
CLINICAL IMMUNOLOGY (2001)
Lymphoid chemokine B cell-attracting chemokine-1 (CXCL13) is expressed in germinal center of ectopic lymphoid follicles within the synovium of chronic arthritis patients
KR Shi et al.
JOURNAL OF IMMUNOLOGY (2001)
Up-regulation of macrophage inflammatory protein-3α/CCL20 and CC chemokine receptor 6 in psoriasis
B Homey et al.
JOURNAL OF IMMUNOLOGY (2000)
Mig, GROα and RANTES messenger RNA expression in lining layer, infiltrates and different leucocyte populations of synovial tissue from patients with rheumatoid arthritis, psoriatic arthritis and osteoarthritis
A König et al.
VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY (2000)
Juvenile chronic arthritis into adulthood: a long-term follow-up study
M Zak et al.
RHEUMATOLOGY (2000)