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Chemical reprogramming takes the fast lane

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CELL STEM CELL
卷 30, 期 4, 页码 335-337

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CELL PRESS
DOI: 10.1016/j.stem.2023.03.001

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Small molecule-induced cell fate transitions have low efficiency and slow kinetics. An optimized chemical reprogramming approach enables the rapid and robust conversion of somatic cells to pluripotent stem cells, providing exciting opportunities to study and manipulate human cell identity.
Small molecule-induced cell fate transitions are characterized by low efficiency and slow kinetics. An opti-mized chemical reprogramming approach now facilitates the robust and rapid conversion of somatic cells to pluripotent stem cells, unlocking exciting avenues to study and manipulate human cell identity.

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